Abstract:
:Therapeutic use of oestrogens by males with carcinoma of the prostate leads to testicular atrophy with markedly reduced spermatogenesis after only 21 d (Oshima et al. 1974). Treatment for over a year results in paucity of germ cells, vacuolation of Sertoli cells and reduction in Leydig cells (Lu & Steinberger 1978, Smith & Urry 1985). There is, apparently, no information on the histology of the human testis after more than 1 year oestrogen therapy. We here report changes in testes from five transsexuals treated for periods of up to 5.5 years.
journal_name
Histopathologyjournal_title
Histopathologyauthors
Venizelos ID,Paradinas FJdoi
10.1111/j.1365-2559.1988.tb01961.xsubject
Has Abstractpub_date
1988-04-01 00:00:00pages
451-4issue
4eissn
0309-0167issn
1365-2559journal_volume
12pub_type
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