Early apocrine change in hyperplastic cystic disease.

abstract：AIMS:Pulmonary Langerhans cell histiocytosis (PLCH) is an idiopathic cigarette smoking-related disorder of the lung. Molecular changes in cellular or fibrotic stages of PLCH have not been investigated. We studied the prevalence of extracellular signal-regulated kinase (ERK) pathway mutations in different PLCH stages an...

journal_title：Histopathology

authors： Kamionek M,Ahmadi Moghaddam P,Sakhdari A,Kovach AE,Welch M,Meng X,Dresser K,Tomaszewicz K,Cosar EF,Mark EJ,Fraire AE,Hutchinson L

更新日期：2016-09-01 00:00:00

abstract：:The CD30 antigen is a characteristic phenotypic feature of Sternberg-Reed and Hodgkin cells and is also found in a subset of large cell non-Hodgkin's lymphomas. The finding of CD30 positive cells in some centroblastic/centrocytic (cb/cc) follicular lymphomas prompted us to characterize the presence and distribution of...

journal_title：Histopathology

authors： Piris M,Gatter KC,Mason DY

更新日期：1991-01-01 00:00:00

abstract：AIMS:Colorectal adenocarcinoma with enteroblastic differentiation (CAED) is a rare malignancy, and its clinicopathological characteristics have not yet been fully elucidated. This study aimed to elucidate the clinicopathological features of CAED through immunostaining of enteroblastic lineage markers alpha-fetoprotein ...

journal_title：Histopathology

authors： Murakami T,Yao T,Yatagai N,Yamashiro Y,Saito T,Sakamoto N,Nagahara A

更新日期：2020-01-01 00:00:00

abstract：AIMS:In T cells, protein kinase C (PKC) theta plays a major role in T-cell receptor (TCR)-mediated activation of a novel nuclear factor (NF)-kappaB pathway that involves phosphorylation of p65 at serine 536 (Pp65(Ser536)). Bcl-10 acts along the same pathway downstream of PKC theta to activate NF-kappaB. The aim was to ...

journal_title：Histopathology

authors： Briones J,Moga E,Espinosa I,Vergara C,Alvarez E,Villa J,Bordes R,Delgado J,Prat J,Sierra J

更新日期：2009-03-01 00:00:00

abstract：AIMS:Colorectal carcinoma (CRC) with micropapillary (MP) features has only been described recently and is still being characterized. METHODS AND RESULTS:We reviewed the clinicopathological and molecular features of 42 CRC with MP features. Twenty-nine cases were also evaluated for immunohistochemical evidence of epith...

journal_title：Histopathology

authors： Gonzalez RS,Huh WJ,Cates JM,Washington K,Beauchamp RD,Coffey RJ,Shi C

更新日期：2017-01-01 00:00:00

abstract：AIMS:To examine the natural history of columnar-lined oesophagus with routinely diagnosed low-grade dysplasia and ascertain the risk of oesophageal adenocarcinoma development. METHODS AND RESULTS:A multicentre retrospective cohort study of 283 patients with low-grade dysplasia. Follow-up data were obtained from examin...

journal_title：Histopathology

authors： Gatenby P,Ramus J,Caygill C,Shepherd N,Winslet M,Watson A

更新日期：2009-06-01 00:00:00

abstract：:To elucidate the role of cell turnover in primary gastric B-cell non-Hodgkin's lymphomas we studied tissue samples of 72 patients-26 small cell (25 MALT lymphomas) and 46 large cell (31 MALT lymphomas). Proliferation indices and apoptotic indices were measured by Mib-1 expression and terminal deoxynucleotidyltransfera...

journal_title：Histopathology

authors： Gisbertz IA,Schouten HC,Bot FJ,Arends JW

更新日期：1997-02-01 00:00:00

abstract：AIMS:  To review the histopathological features of cervical LNs, and to clarify the changes in extracervical LNs, in acute Kawasaki disease (KD). METHODS AND RESULTS:  The samples were obtained from 33 patients with acute-phase KD. We divided the LNs into those in the neck (n = 23) and those located elsewhere (n = 26)...

journal_title：Histopathology

authors： Yokouchi Y,Oharaseki T,Harada M,Ihara F,Naoe S,Takahashi K

更新日期：2013-02-01 00:00:00

abstract：:The detailed documentation of ocular pathology has become an important component in the autopsy investigation of suspected cases of non-accidental injury in infants and young children. Careful histological examination of retinal haemorrhages is of critical importance, but there remains debate about the significance of...

journal_title：Histopathology

authors： Gilliland MG,Luthert P

更新日期：2003-12-01 00:00:00

abstract：:The immunohistochemistry of the cell population of the human spleen was studied. As controls, a strictly defined group of five specimens were used. This study stresses the need for the utmost care in this selection procedure. Using enzyme- and immuno-histochemistry the lymphocyte subpopulations were studied as to thei...

journal_title：Histopathology

authors： van Krieken JH,te Velde J

更新日期：1986-03-01 00:00:00

abstract：:Upper gastrointestinal endoscopic examination of 40 patients on immunosuppressive therapy after successful kidney transplantation revealed a duodenal ulcer in four cases and duodenal erosions in six. Between four and six biopsies were collected from the antral and the fundal mucosa in each case and from the duodenal m...

journal_title：Histopathology

authors： Franzin G,Musola R,Mencarelli R

更新日期：1982-07-01 00:00:00

abstract：AIMS:Ossification is found occasionally in dedifferentiated liposarcoma (DDLPS). The aims of this study were to elucidate whether the formed bone tissue is usually produced by tumour cells or by reactive non-neoplastic cells, and to reveal the clinicopathological characteristics of DDLPS with ossification. METHODS AND...

journal_title：Histopathology

authors： Yamashita K,Kohashi K,Yamada Y,Ishii T,Nishida Y,Urakawa H,Ito I,Takahashi M,Inoue T,Ito M,Ohara Y,Oda Y,Toyokuni S

更新日期：2018-04-01 00:00:00

abstract：AIM:To determine the extent of clonal outgrowth in the lymphocytic tissue infiltrate of lichen sclerosus (LS). The presence of T cells with a monoclonally rearranged T-cell receptor gamma-gene (TCRgamma) has been described in up to 50% of biopsies of vulvar and penile LS. MATERIAL AND RESULTS:We analysed 33 foreskin s...

journal_title：Histopathology

authors： Regauer S,Beham-Schmid C

更新日期：2006-05-01 00:00:00

abstract：:Forty cases of the distinctive but poorly recognized aneurysmal variant of cutaneous fibrous histiocytoma are described. These tumours presented most commonly in middle-age adults, with a slight predilection for females. Anatomical distribution was wide with most cases occurring in the lower limb/limb girdle (50%), up...

journal_title：Histopathology

authors： Calonje E,Fletcher CD

更新日期：1995-04-01 00:00:00

abstract：AIMS:Adenoid cystic carcinoma (AdCC) of the salivary glands shows heterogeneous behaviour, with metastasis as a key indicator of poor prognosis. Metallothionein (MT) expression has been associated with poor prognosis of diverse neoplasms. We evaluated prognostic factors for AdCC and the role played by MT, focusing on m...

journal_title：Histopathology

authors： Brazão-Silva MT,Cardoso SV,de Faria PR,Dias FL,Lima RA,Eisenberg AL,Nascimento MF,Loyola AM

更新日期：2013-12-01 00:00:00

abstract：:A total of 118 biopsies from 20 different types of benign, malignant and reactive vascular proliferations were examined for the expression of the CD30 antigen using the monoclonal antibodies BerH2 and HRS4 on paraffin-embedded sections. The results were compared with those obtained using an antibody directed against t...

journal_title：Histopathology

authors： Rudolph P,Lappe T,Schmidt D

更新日期：1993-08-01 00:00:00

abstract：AIMS:Cystic lesions derived from the synovial and ligamentous structures of the spine have varied histological appearances. Not uncommonly, there is discrepancy between the clinicoradiological diagnosis and histology. Therefore, we sought to characterise the histological features of tissue submitted as 'synovial cysts'...

journal_title：Histopathology

authors： Chebib I,Chang CY,Schwab JH,Kerr DA,Deshpande V,Nielsen GP

更新日期：2018-05-01 00:00:00

abstract：AIMS:We have previously shown that hypertrophic scar tissue from burn patients contains abnormally high amounts of the proteoglycans versican and biglycan and reduced amounts of decorin, in comparison with normal dermis or mature scar. The lack of decorin may account for the poor organization of collagen fibrils in the...

journal_title：Histopathology

authors： Sayani K,Dodd CM,Nedelec B,Shen YJ,Ghahary A,Tredget EE,Scott PG

更新日期：2000-03-01 00:00:00

abstract：AIMS:Calretinin, a calcium-binding protein, is expressed primarily in certain subtypes of neurons. It has also been reported to be present in mesotheliomas and other tumours. The aim was to determine the expression of calretinin in selected odontogenic neoplasms. METHODS AND RESULTS:Immunohistochemistry for calretinin...

journal_title：Histopathology

authors： Alaeddini M,Etemad-Moghadam S,Baghaii F

更新日期：2008-02-01 00:00:00

abstract：AIMS:To analyse the possible activation of distinct molecular pathways in mucosa-associated lymphoid tissue (MALT) lymphoma, we determined the prevalence of trisomies 3, 12, 18 in MALT lymphomas from different organs, as well as the prevalence of translocations of the MALT1 gene in a subset of primary breast MALT lymph...

journal_title：Histopathology

authors： João C,Farinha P,da Silva MG,Martins C,Crespo M,Cabeçadas J

更新日期：2007-01-01 00:00:00

abstract：AIMS:  Follicular lymphoma (FL) is associated with bone marrow (BM) involvement in approximately 40-70% of cases. Previous studies have suggested that the immune-microenvironment of FL plays an important role in the clinical behaviour of the disease. To investigate the role of the microenvironment in BM involvement of ...

journal_title：Histopathology

authors： Rajnai H,Bödör C,Balogh Z,Gagyi E,Csomor J,Krenács T,Tóth E,Matolcsy A

更新日期：2012-05-01 00:00:00

abstract：:We report three cases of an unusual primary carcinoma of the liver composed of small cells. The patients were adult males (56 to 89 years) who presented with jaundice, weight loss and abdominal discomfort. Surgery was attempted in one case. Clinical evolution was rapid, with death ensuing between 1 and 5 months after ...

journal_title：Histopathology

authors： Zanconati F,Falconieri G,Lamovec J,Zidar A

更新日期：1996-11-01 00:00:00

abstract：:Morphometric methods were applied to predict the clinical course of individual patients with breast cancer. Measurement of tumour diameter, assessment of mitotic and cellular indices, and quantitative microscopy of nuclear features were assessed together with nuclear features and histological grades. Of the tumours fr...

journal_title：Histopathology

authors： Baak JP,Kurver PH,De Snoo-Niewlaat AJ,De Graef S,Makkink B,Boon ME

更新日期：1982-05-01 00:00:00

abstract：AIMS:To compare the morphological and immunohistochemical characteristics of oestrogen receptor (ER)-negative and ER-positive ductal carcinoma in situ (DCIS) of the breast, in an attempt to establish more objective criteria for the classification of DCIS. METHODS AND RESULTS:Sections of 64 cases of in-situ carcinoma o...

journal_title：Histopathology

authors： Baqai T,Shousha S

更新日期：2003-05-01 00:00:00

abstract：AIMS:Biliary intraductal tubular neoplasms that are non-mucinous and negative for mucin 5AC (MUC5AC) are called intraductal tubulopapillary neoplasms (ITPNs). Intraductal tubular neoplasms with mucinous cytoplasm and MUC5AC positivity also occur and their nature remains unclear, although some pathologists may classify ...

journal_title：Histopathology

authors： Akita M,Hong SM,Sung YN,Kim MJ,Ajiki T,Fukumoto T,Itoh T,Zen Y

更新日期：2020-06-01 00:00:00

abstract：AIMS:BCOR gene alteration is a genetic signature of rare subsets of sarcomas. Most BCOR-associated sarcomas thus far reported are in the pediatric population, except for uterine sarcomas. We studied seven cases of BCOR-associated non-uterine sarcomas in adult patients. METHODS AND RESULTS:The patients were four men an...

journal_title：Histopathology

authors： Yoshida A,Arai Y,Hama N,Chikuta H,Bando Y,Nakano S,Kobayashi E,Shibahara J,Fukuhara H,Komiyama M,Watanabe SI,Tamura K,Kawai A,Shibata T

更新日期：2020-03-01 00:00:00

abstract：AIMS:Biphenotypic sinonasal sarcoma (SNS) is a locally aggressive tumour that occurs in the sinonasal region. PAX3-MAML3 has recently been identified as a recurrent fusion gene event in this entity; however, a subset of tumours harbour alternative PAX3 rearrangement without the involvement of MAML3. In this study we so...

journal_title：Histopathology

authors： Fritchie KJ,Jin L,Wang X,Graham RP,Torbenson MS,Lewis JE,Rivera M,Garcia JJ,Schembri-Wismayer DJ,Westendorf JJ,Chou MM,Dong J,Oliveira AM

更新日期：2016-12-01 00:00:00

abstract：:One hundred and two cases of poorly differentiated adenocarcinoma were obtained from 71 surgical and 31 biopsy specimens of the stomach. These tumours produced both intracellular and extracellular mucins, which were demonstrated to be neutral mucins, N-acetyl sialomucins, sulphomucins and O-acetyl sialomucins. The maj...

journal_title：Histopathology

authors： Huang CB,Li WC,Xu J,Zhang YC

更新日期：1988-05-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：:A mapping study of cystectomy specimens in three cases of pure squamous cell carcinoma and 28 cases with transitional cell carcinoma with squamous differentiation is described, with an emphasis on the histogenesis of pure squamous cell carcinoma. Two of the three cases of pure squamous cell carcinoma had extensive ben...

journal_title：Histopathology

authors： Sakamoto N,Tsuneyoshi M,Enjoji M

更新日期：1992-08-01 00:00:00