Proliferation and apoptosis in primary gastric B-cell non-Hodgkin's lymphoma.

abstract：:Expression of the epidermal growth factor receptor (EGFR) was studied in cryosections from human thyroid tissues. Normal tissue (4 cases), nodular goitre (12), toxic goitre (9), adenoma (9), follicular carcinoma (1), papillary carcinoma (7) and poorly differentiated carcinoma (1) were used for immunohistochemistry. No...

journal_title：Histopathology

authors： Westermark K,Lundqvist M,Wallin G,Dahlman T,Hacker GW,Heldin NE,Grimelius L

更新日期：1996-03-01 00:00:00

abstract：AIMS:Telomerase is reactivated in most cancers and there is accumulating evidence that this is a driver event in malignant melanoma (MM). Thus, our aim was to evaluate if in-situ hybridization (ISH)-based quantification of telomerase RNA (hTR) could be used to distinguish MM from naevi, and if there was a correlation w...

journal_title：Histopathology

authors： Vagner J,Steiniche T,Stougaard M

更新日期：2015-04-01 00:00:00

abstract：:In reviewing a large series of soft tissue tumours, seven cases of benign plexiform schwannoma have been retrieved. These were solitary lesions, not associated with von Recklinghausen's neurofibromatosis, which arose in the dermis or subcutaneous tissue, predominantly in young adults. None has recurred. While the schw...

journal_title：Histopathology

authors： Fletcher CD,Davies SE

更新日期：1986-09-01 00:00:00

abstract：:We reviewed 45 pulmonary B-cell non-Hodgkin's lymphomas to determine whether their morphology and immunohistochemical features were those of lymphomas arising from mucosa-associated lymphoid tissue (MALT), as described in other sites. The polymerase chain reaction was used to provide further information on clonality. ...

journal_title：Histopathology

authors： Nicholson AG,Wotherspoon AC,Diss TC,Butcher DN,Sheppard MN,Isaacson PG,Corrin B

更新日期：1995-05-01 00:00:00

abstract：AIMS:More than 50% of neuroblastomas (NBs) present with haematogenous and/or lymphatic metastasis; however, little is known about the clinicopathological significance in NBs of the key lymphangiogenesis growth factors vascular endothelial growth factor (VEGF)-C and VEGF-D and the receptor VEGFR-3. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Ramani P,Nash R,Radevsky L,Patel A,Luckett M,Rogers C

更新日期：2012-12-01 00:00:00

abstract：AIMS:To characterise the mutational profiles of poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) and to identify markers with potential diagnostic, prognostic and therapeutic significance. METHODS AND RESULTS:Targeted next-generation sequencing with a panel of 18 thyroid carcinoma-...

journal_title：Histopathology

authors： Duan H,Li Y,Hu P,Gao J,Ying J,Xu W,Zhao D,Wang Z,Ye J,Lizaso A,He Y,Wu H,Liang Z

更新日期：2019-12-01 00:00:00

abstract：AIMS:To validate the use of the silver-enhanced in situ hybridization (SISH) technique in assessing HER2 status of breast carcinoma in excision biopsy specimens, and to assess its reliability in determining HER2 status in core biopsy specimens. METHODS AND RESULTS:Routinely processed paraffin sections of 65 excised br...

journal_title：Histopathology

authors： Shousha S,Peston D,Amo-Takyi B,Morgan M,Jasani B

更新日期：2009-01-01 00:00:00

abstract：AIMS:Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) is a downstream effector of Ras signalling, and is overexpressed in several types of human malignancy. However, its role in gastric cancer remains unclear. The aim of this study was to investigate the prognostic significance of G3BP1 in gastric can...

journal_title：Histopathology

authors： Min L,Ruan Y,Shen Z,Jia D,Wang X,Zhao J,Sun Y,Gu J

更新日期：2015-11-01 00:00:00

abstract：AIMS:Tumour necrosis factor (TNF)-alpha induces death or cell proliferation by activation of nuclear factor (NF)-kappaB, also activated by interleukin (IL)-1 alpha. The aim was to investigate upstream and downstream components of NIK transduction pathway in normal (NP), benign prostatic hyperplasia (BPH), prostatic int...

journal_title：Histopathology

authors： Nuñez C,Cansino JR,Bethencourt F,Pérez-Utrilla M,Fraile B,Martínez-Onsurbe P,Olmedilla G,Paniagua R,Royuela M

更新日期：2008-08-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：AIMS:In oesophageal adenocarcinoma, detection rates of venous invasion using haematoxylin and eosin (H&E) and elastic stains have not been compared. The aims of this study were to investigate whether or not elastic stains facilitate the detection of venous invasion, and to determine the prognostic significance of venou...

journal_title：Histopathology

authors： Castonguay MC,Li-Chang HH,Driman DK

更新日期：2014-04-01 00:00:00

abstract：AIMS:Previous karyotyping and fluorescence in situ hybridization analysis of metanephric adenomas (MAs) has yielded controversial data. The aim of this study was to detect small genomic alterations, if any, specific to MAs by applying high-resolution oligoarrays. METHODS AND RESULTS:DNA extracted from paraffin blocks ...

journal_title：Histopathology

authors： Szponar A,Yusenko MV,Kovacs G

更新日期：2010-01-01 00:00:00

abstract：AIMS:To investigate whether localization of beta-catenin is helpful in differentiating primary ovarian mucinous carcinoma and colorectal adenocarcinoma metastatic to the ovary. Extra-ovarian cancers which metastasize to the ovaries, especially from colorectal adenocarcinoma, frequently mimic primary ovarian carcinomas,...

journal_title：Histopathology

authors： Chou YY,Jeng YM,Kao HL,Chen T,Mao TL,Lin MC

更新日期：2003-08-01 00:00:00

abstract：:The benign 'Triton' tumour is a neural tumour with benign rhabdomyomatous differentiation: it must be distinguished from the better known malignant counterpart. We describe the first case outside the peripheral soft tissues and the first to be studied ultrastructurally. It also represents the second lesion identified ...

journal_title：Histopathology

authors： Azzopardi JG,Eusebi V,Tison V,Betts CM

更新日期：1983-07-01 00:00:00

abstract：AIM:Primary cutaneous neuroendocrine carcinoma, or Merkel cell carcinoma (MCC), cannot be distinguished morphologically from small-cell neuroendocrine carcinomas (SmCC) from other sites. Immunohistochemistry is required to confirm cutaneous origin, and is also used for detection of sentinel lymph node (SLN) metastases ...

journal_title：Histopathology

authors： Stanoszek LM,Chan MP,Palanisamy N,Carskadon S,Siddiqui J,Patel RM,Harms KL,Lowe L,Fullen DR,Harms PW

更新日期：2019-02-01 00:00:00

abstract：AIMS:Small cell (neuroendocrine) carcinoma of the urinary bladder is clinically more aggressive than urothelial (transitional cell) carcinoma. We have investigated the immunohistochemical markers most useful in diagnosing small cell carcinoma in bladder. METHODS AND RESULTS:We evaluated the expression of chromogranin ...

journal_title：Histopathology

authors： Iczkowski KA,Shanks JH,Allsbrook WC,Lopez-Beltran A,Pantazis CG,Collins TR,Wetherington RW,Bostwick DG

更新日期：1999-08-01 00:00:00

abstract：AIMS:Restrictive allograft syndrome (RAS) and idiopathic pleuroparenchymal fibroelastosis (IPPFE) are two different diseases reported to share the same histology. RAS relates to chronic allograft dysfunction in lung transplantation, with IPPFE being a rare condition in native lungs. Our aim is to compare their histolog...

journal_title：Histopathology

authors： Montero MA,Osadolor T,Khiroya R,Salcedo MT,Robertus JL,Rice A,Nicholson AG,Roman A,Monforte V

更新日期：2017-06-01 00:00:00

abstract：:The generic term aggressive B-cell lymphoma includes a variety of entities, each with particular diagnostic and therapeutic issues. To define these entities better and to help confront such issues, a workshop was organized by the European Association of Haematopathology (EAHP) and the Society of Haematology during the...

journal_title：Histopathology

authors： Leoncini L,Delsol G,Gascoyne RD,Harris NL,Pileri SA,Piris MA,Stein H

更新日期：2005-03-01 00:00:00

abstract：AIMS:Conflicting data on c-erbB-2 overexpression in gastric carcinomas can be found in the literature with regard to overall prevalence, prognostic significance and the histological type according to Lauren. The majority of these studies have focused on advanced gastric carcinomas whereas data on c-erbB-2 overexpressio...

journal_title：Histopathology

authors： Blok P,Craanen ME,Dekker W,Offerhaus GJ,Tytgat GN

更新日期：1998-04-01 00:00:00

abstract：:Elastosis, a previously unreported feature, was found to be common in granular cell tumours. Twenty-four of 28 consecutive granular cell tumours were shown to display elastosis. The elastosis was found in three main sites: adventitial, interstitial and septal. Elastosis is statistically associated with the fibrosis pr...

journal_title：Histopathology

authors： McMahon JN,Rigby HS,Davies JD

更新日期：1990-01-01 00:00:00

abstract：:This study demonstrates the presence of three antigens in glandular metaplasia occurring in patients with cholecystitis and cholelithiasis: specifically carcinoembryonic antigen (CEA), large intestinal mucin antigen (LIMA) and small intestinal mucin antigen (SIMA). These antigens could not be detected in normal gall b...

journal_title：Histopathology

authors： De Boer WG,Ma J,Rees JW,Nayman J

更新日期：1981-05-01 00:00:00

abstract：AIMS:Class III beta-tubulin (TUBB3) reduces microtubule stability and confers resistance to microtubule-stabilizing taxanes, including paclitaxel and docetaxel. Pancreatic ductal adenocarcinomas show limited responsiveness to taxanes, but little is known of the underlying mechanisms. The aim of this study was to examin...

journal_title：Histopathology

authors： Lee KM,Cao D,Itami A,Pour PM,Hruban RH,Maitra A,Ouellette MM

更新日期：2007-10-01 00:00:00

abstract：:Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

journal_title：Histopathology

authors： Browne RM,Rippin JW

更新日期：1984-11-01 00:00:00

abstract：:Nephropathy remains a major cause of morbidity and mortality in diabetes mellitus and increasing numbers of patients require dialysis maintenance therapy. Diagnostic criteria of diabetic nephropathy are well established, but the relationship between the morphological changes of glomerular basement membrane thickening ...

journal_title：Histopathology

authors： Morley AR

更新日期：1988-04-01 00:00:00

abstract：AIMS:SOX11 is known as an essential transcription factor for regulating neurogenesis. Recently, SOX11 has been suggested to be a diagnostic marker and oncogene because of its significant expression in mantle cell lymphoma (MCL). However, SOX11 expression in other tumour types has not yet been extensively studied. METH...

journal_title：Histopathology

authors： Xu S,Dong Y,Huo Z,Yu L,Xue J,Wang G,Duan Y

更新日期：2019-02-01 00:00:00

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：:An example of a cutaneous ciliated cyst in the buttock of a 42 year old woman is reported. The histological and immunohistochemical features of the cyst are presented: comparisons with fallopian tube are made and this rare lesion is discussed. ...

journal_title：Histopathology

authors： al-Nafussi AI,Carder P

更新日期：1990-06-01 00:00:00

abstract：:A Sertoli-Leydig cell tumour of testis presented some diagnostic difficulties. The tumour cells showed strong expression of S-100 antigen. Preliminary study of non-neoplastic testis suggests that Leydig cells and, to a lesser extent, Sertoli cells express S-100 antigen; its localization may be of value in the diagnosi...

journal_title：Histopathology

authors： McLaren K,Thomson D

更新日期：1989-12-01 00:00:00

abstract：AIMS:SOX2 is a key regulatory gene in embryonic stem cells. Although it has been implicated in cancer progression, its role in breast carcinoma is poorly understood. MATERIALS AND METHODS:Fifty-seven ductal carcinomas in situ (DCIS), 552 invasive breast carcinomas and 107 corresponding metastatic lymph nodes were eval...

journal_title：Histopathology

authors： Huang YH,Luo MH,Ni YB,Tsang JY,Chan SK,Lui PC,Yu AM,Tan PH,Tse GM

更新日期：2014-03-01 00:00:00

abstract：:Gonadoblastoma is defined as a neoplasm containing nests of germ cells and cells resembling Sertoli cells or granulosa cells. Gonadoblastomas arise almost exclusively in dysgenetic gonads. They are associated with an increased risk of developing germ cell tumours. Testicular germ cell tumours in adults are preceded by...

journal_title：Histopathology

authors： Jørgensen N,Müller J,Jaubert F,Clausen OP,Skakkebaek NE

更新日期：1997-02-01 00:00:00