Pleuroparenchymal fibroelastosis and non-specific interstitial pneumonia: frequent pulmonary sequelae of haematopoietic stem cell transplantation.

abstract：AIMS:The presence of micrometastases in the sentinel lymph node (SLN) is an important prognostic parameter for melanoma patients. The aim was to determine the prognostic relevance of histopathological characteristics of micrometastases in the SLN, which has not been adequately addressed thus far. METHODS AND RESULTS:I...

journal_title：Histopathology

authors： Satzger I,Völker B,Al Ghazal M,Meier A,Kapp A,Gutzmer R

更新日期：2007-05-01 00:00:00

abstract：AIMS:To investigate the role of BNIP3, a 19-kDa interacting protein of the Bcl-2 family, alongside Bcl-2 in follicular lymphoma in comparison with reactive lymphoid hyperplasia. The results were compared with those from p53 and caspase-3 (apoptotic markers) and Ki67 (proliferation marker). METHODS AND RESULTS:Immunohi...

journal_title：Histopathology

authors： Sington J,Giatromanolaki A,Campo L,Turley H,Pezzella F,Gatter KC

更新日期：2007-04-01 00:00:00

abstract：:Chromosomal rearrangements resulting in the fusion of coding parts from two genes or in the exchange of regulatory sequences are present in approximately 20% of all human neoplasms. More than 1000 such gene fusions have now been described, with close to 100 of them in soft tissue tumours. Although little is still know...

journal_title：Histopathology

authors： Mertens F,Tayebwa J

更新日期：2014-01-01 00:00:00

abstract：AIMS:Follicular lymphoma (FL) in situ is defined as strongly bcl-2-positive B cells in germinal centres of morphologically inconspicuous lymph nodes. The prevalence and biological and clinical significance of this lesion are still not clear. Therefore we aimed at the detection of the prevalence of this phenomenon in an...

journal_title：Histopathology

authors： Henopp T,Quintanilla-Martínez L,Fend F,Adam P

更新日期：2011-07-01 00:00:00

abstract：AIMS:The clinicopathological distinctiveness of nodal cytotoxic molecule (CM)-positive Epstein-Barr virus (EBV)-associated peripheral T cell lymphoma (PTCL) remains to be clarified. We investigated 26 patients with this lymphoma compared to nodal CM(+) EBV(-) PTCL (n = 39) and extranasal natural killer/T cell lymphoma ...

journal_title：Histopathology

authors： Kato S,Takahashi E,Asano N,Tanaka T,Megahed N,Kinoshita T,Nakamura S

更新日期：2012-08-01 00:00:00

abstract：AIMS:Pseudosarcomatous myofibroblastic proliferations (PSMPs) of the urinary bladder are diagnostically challenging. Diagnostic difficulties are mainly due to frequent cytokeratin expression, variable ALK expression and worrisome morphological features suggestive of malignancy. Conversely, sarcomatoid urothelial carcin...

journal_title：Histopathology

authors： Bertz S,Stöhr R,Gaisa NT,Wullich B,Hartmann A,Agaimy A

更新日期：2020-12-01 00:00:00

abstract：:The histopathological classification of ovarian surface epithelial carcinomas (referred to hereafter as 'ovarian carcinoma') has shifted over the past 10 years to reflect more clearly our understanding of molecular events during carcinogenesis. Ovarian carcinoma is no longer viewed as a single entity but as multiple d...

journal_title：Histopathology

authors： Gurung A,Hung T,Morin J,Gilks CB

更新日期：2013-01-01 00:00:00

abstract：:This review intends to update current knowledge regarding molecular cytogenetics in melanocytic tumours with a focus on cutaneous melanocytic lesions. Advantages and limitations of diverse, already established methods, such as (fluorescence) in situ hybridization and mutation analysis, to detect these cytogenetic alte...

journal_title：Histopathology

authors： Blokx WA,van Dijk MC,Ruiter DJ

更新日期：2010-01-01 00:00:00

abstract：AIMS:Adenoid cystic carcinoma (AdCC) of the salivary glands shows heterogeneous behaviour, with metastasis as a key indicator of poor prognosis. Metallothionein (MT) expression has been associated with poor prognosis of diverse neoplasms. We evaluated prognostic factors for AdCC and the role played by MT, focusing on m...

journal_title：Histopathology

authors： Brazão-Silva MT,Cardoso SV,de Faria PR,Dias FL,Lima RA,Eisenberg AL,Nascimento MF,Loyola AM

更新日期：2013-12-01 00:00:00

abstract：AIMS:To investigate the clinicopathological and molecular characteristics, immunohistochemical profile and prognosis of pulmonary adenocarcinoma with a micropapillary pattern (MPPAC). METHODS AND RESULTS:Eight hundred and eighty-six pulmonary adenocarcinomas were divided into two groups: micropapillary pattern (MPP)-p...

journal_title：Histopathology

authors： Zhang J,Liang Z,Gao J,Luo Y,Liu T

更新日期：2011-12-01 00:00:00

abstract：:A review of 76 endomyocardial biopsies and 54 autopsies of patients with dilated cardiomyopathy (DCM) revealed features of hypertrophy and degenerative changes associated with long-standing hypertrophy. Long-term survivors had significantly heavier heart weights. Short-term survivors had heavier than normal right vent...

journal_title：Histopathology

authors： Rose AG,Beck W

更新日期：1985-04-01 00:00:00

abstract：:Twenty-nine cases of non-Hodgkin's lymphoma of low-grade malignancy in a European population were investigated for the presence of bcl-2 and bcl-1 gene rearrangement. The cases were classified according to the Kiel classification. It was shown that bcl-2 gene rearrangements were exclusively confined to centroblastic-c...

journal_title：Histopathology

authors： Ott MM,Müller-Hermelink HK,Schmitt B,Feller AC

更新日期：1991-08-01 00:00:00

abstract：AIMS:To study the relevance of periostin, known to be involved in epithelial-mesenchymal transition (EMT), in hepatocellular and bile duct cancer. METHODS AND RESULTS:Immunohistochemical periostin expression was semiquantitatively analysed in normal liver tissue (n = 20), hepatocellular carcinoma (HCC; n = 91), liver-...

journal_title：Histopathology

authors： Riener MO,Fritzsche FR,Soll C,Pestalozzi BC,Probst-Hensch N,Clavien PA,Jochum W,Soltermann A,Moch H,Kristiansen G

更新日期：2010-04-01 00:00:00

abstract：:Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are derived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis i...

journal_title：Histopathology

authors： Tan SY,Pepys MB

更新日期：1994-11-01 00:00:00

abstract：AIMS:Helicobacter pylori has been claimed to be an important aetiological factor which raises the risk of mucosa-associated tissue lymphoid (MALT) lymphoma. However, some studies on gastric MALT lymphoma revealed a low rate of H. pylori infection suggesting that not all gastric lymphomas are related to H. pylori infect...

journal_title：Histopathology

authors： Bouzourene H,Haefliger T,Delacretaz F,Saraga E

更新日期：1999-02-01 00:00:00

abstract：:Three cases are reported in which an initial diagnosis of the plasma cell variant of Castleman's disease was made, but in which a second lymph node biopsy within a year showed evidence of Hodgkin's disease. Review of the initial biopsy indicated that atypical CD15 and CD30 positive cells were present in the initial bi...

journal_title：Histopathology

authors： Maheswaran PR,Ramsay AD,Norton AJ,Roche WR

更新日期：1991-03-01 00:00:00

abstract：AIMS:To investigate the protein expressions of breast cancer 1 (BRCA1) and 2 (BRCA2) in prostatectomy specimens of localized prostate cancer (PC) patients, along with their associations with cancer characteristics and prognosis. METHODS AND RESULTS:Immunohistochemistry for BRCA1 and BRCA2 was performed on tissue micro...

journal_title：Histopathology

authors： Kim SH,Park WS,Yun SI,Joo J,Joung JY,Seo HK,Chung J,Lee GK,Lee KH

更新日期：2016-04-01 00:00:00

abstract：AIMS:We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF). METHODS AND RESULTS:A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial in...

journal_title：Histopathology

authors： Serrano R,Martínez MA,Andrés A,Morales JM,Samartin R

更新日期：1998-08-01 00:00:00

abstract：:The morphology, phenotype, genotype and clinical behaviour of four cases of mantle cell lymphoma (centrocytic lymphoma) presenting primarily in mucosa (two gastric, one in large bowel and one tonsillar) are reviewed. Their relationship with the broader group of mantle cell and mucosa-associated lymphoid tissue (MALT) ...

journal_title：Histopathology

authors： Fraga M,Lloret E,Sanchez-Verde L,Orradre JL,Campo E,Bosch F,Piris MA

更新日期：1995-05-01 00:00:00

abstract：AIMS:Pulmonary artery (PA) dissection is a rare event which usually occurs in patients with underlying pulmonary hypertension. We describe two patients who developed PA dissection without pre-existing pulmonary hypertension and present an extensive review of the literature. METHODS AND RESULTS:In the first patient (a ...

journal_title：Histopathology

authors： Inayama Y,Nakatani Y,Kitamura H

更新日期：2001-05-01 00:00:00

abstract：AIMS:Rare gastric lesions composed of a combined proliferation of chief and oxyntic cells have been variably called adenocarcinoma of fundic gland type and oxyntic gland polyp/adenoma. Herein, we present a series of cases that show a morphological spectrum of chief and oxyntic cell proliferations. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Chan K,Brown IS,Kyle T,Lauwers GY,Kumarasinghe MP

更新日期：2016-05-01 00:00:00

abstract：:An example of a cutaneous ciliated cyst in the buttock of a 42 year old woman is reported. The histological and immunohistochemical features of the cyst are presented: comparisons with fallopian tube are made and this rare lesion is discussed. ...

journal_title：Histopathology

authors： al-Nafussi AI,Carder P

更新日期：1990-06-01 00:00:00

abstract：:Two cases of papillary and cystic neoplasm of the pancreas (PCN) occurring in 17 and 21 year old women are reported with ultrastructural and immunohistochemical findings. A review of the English literature shows that although potentially malignant, PCN, which occurs mainly in young women, is amenable to surgical cure....

journal_title：Histopathology

authors： Learmonth GM,Price SK,Visser AE,Emms M

更新日期：1985-01-01 00:00:00

abstract：AIMS:Five cases of a characteristic low-grade thymic epithelial tumour are described that we suggest calling metaplastic carcinoma of the thymus. METHODS AND RESULTS:The patients' ages ranged from 44 to 71 (mean 56.2) years. Four of the patients were male. Three of five tumours showed invasion into mediastinal fat or ...

journal_title：Histopathology

authors： Yoneda S,Marx A,Heimann S,Shirakusa T,Kikuchi M,Müller-Hermelink HK

更新日期：1999-07-01 00:00:00

abstract：AIMS:To study the pathogenesis of tumoral calcinosis (TC), we investigated 111 cases registered in Zaire over 30 years. METHODS AND RESULTS:The patients were 108 black Africans and three Caucasians between 3 and 74 years of age (mean, 37.7; median, 39). The gender was known in 33 males and 46 females; in 79 the gender...

journal_title：Histopathology

authors： Pakasa NM,Kalengayi RM

更新日期：1997-07-01 00:00:00

abstract：AIMS:Tumour necrosis factor (TNF)-alpha induces death or cell proliferation by activation of nuclear factor (NF)-kappaB, also activated by interleukin (IL)-1 alpha. The aim was to investigate upstream and downstream components of NIK transduction pathway in normal (NP), benign prostatic hyperplasia (BPH), prostatic int...

journal_title：Histopathology

authors： Nuñez C,Cansino JR,Bethencourt F,Pérez-Utrilla M,Fraile B,Martínez-Onsurbe P,Olmedilla G,Paniagua R,Royuela M

更新日期：2008-08-01 00:00:00

abstract：AIMS:  Poorly differentiated thyroid carcinomas (PDTC) are an ongoing diagnostic challenge. Although the Turin consensus criteria for PDTC excluded consideration of oncocytic tumours, the World Health Organization (WHO) classification does recognise an oncocytic variant of conventional PDTC. The aims of this study were...

journal_title：Histopathology

authors： Dettmer M,Schmitt A,Steinert H,Moch H,Komminoth P,Perren A

更新日期：2012-06-01 00:00:00

abstract：AIMS:To estimate the likelihood of the upgrade for atypical ductal hyperplasia (ADH) diagnosed on a core needle biopsy of a mammographically detected lesion. METHODS AND RESULTS:A total of 203 consecutive ADH cases diagnosed on core biopsy in mammographically detected lesions and having subsequent surgical excision we...

journal_title：Histopathology

authors： Khoury T,Chen X,Wang D,Kumar P,Qin M,Liu S,Turner B

更新日期：2015-07-01 00:00:00

abstract：AIMS:We sought to delineate and describe three cases of a distinctive mesenchymal neoplasm of the vulva showing adipocytic differentiation and affecting young patients. METHODS AND RESULTS:In three patients between 13 and 38 years of age, the vulvar tumours had well-circumscribed borders and ranged in size from 35 to ...

journal_title：Histopathology

authors： Lae ME,Pereira PF,Keeney GL,Nascimento AG

更新日期：2002-06-01 00:00:00

abstract：:High levels of bcl-2 protein have been found in a wide variety of human cancers. Since p53 gene inactivation occurs in over half of human cancers, it is possible that loss of p53-mediated repression of bcl-2 gene expression accounts, at least in part, for the frequent abnormalities in bcl-2 protein production seen in ...

journal_title：Histopathology

authors： Harn HJ,Ho LI,Liu CA,Liu GC,Lin FG,Lin JJ,Chang JY,Lee WH

更新日期：1996-04-01 00:00:00