Hodgkin's disease presenting with the histological features of Castleman's disease.

Abstract:

:Three cases are reported in which an initial diagnosis of the plasma cell variant of Castleman's disease was made, but in which a second lymph node biopsy within a year showed evidence of Hodgkin's disease. Review of the initial biopsy indicated that atypical CD15 and CD30 positive cells were present in the initial biopsy. This illustrates the difficulty in making the diagnosis of Castleman's disease and suggests that the lymphoid reaction to the presence of Hodgkin's disease may result in similar histological appearances. The need for re-evaluation of the diagnosis of Castleman's disease in the face of persistent or recurrent disease is stressed.

journal_name

Histopathology

journal_title

Histopathology

authors

Maheswaran PR,Ramsay AD,Norton AJ,Roche WR

doi

10.1111/j.1365-2559.1991.tb00833.x

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

249-53

issue

3

eissn

0309-0167

issn

1365-2559

journal_volume

18

pub_type

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