Non-endothelial KDR/flk-1 expression is associated with increased survival of patients with urothelial bladder carcinomas.

abstract：AIMS:We present the histopathological findings of a series of six cases of a benign uterine smooth muscle tumour with an unusual growth pattern. METHODS AND RESULTS:All cases have the appearances of the recently described dissecting (cotyledonoid) leiomyoma. In addition, three of these lesions demonstrate the features...

journal_title：Histopathology

authors： Jordan LB,Al-Nafussi A,Beattie G

更新日期：2002-03-01 00:00:00

abstract：AIMS:Colorectal adenocarcinoma with enteroblastic differentiation (CAED) is a rare malignancy, and its clinicopathological characteristics have not yet been fully elucidated. This study aimed to elucidate the clinicopathological features of CAED through immunostaining of enteroblastic lineage markers alpha-fetoprotein ...

journal_title：Histopathology

authors： Murakami T,Yao T,Yatagai N,Yamashiro Y,Saito T,Sakamoto N,Nagahara A

更新日期：2020-01-01 00:00:00

abstract：AIMS:We evaluated polymerase chain reaction (PCR) amplification of specific immunoglobulin heavy chain (IgH) gene rearrangements as a means of demonstrating monoclonality during follow-up of conservatively treated gastric MALT lymphoma, and compared the reproducibility of PCR on sequential frozen and paraffin-embedded ...

journal_title：Histopathology

authors： Aiello A,Giardini R,Tondini C,Balzarotti M,Diss T,Peng H,Delia D,Pilotti S

更新日期：1999-04-01 00:00:00

abstract：AIMS:Carbonic anhydrase VI (CA6) is present in serous acinar cells of human salivary glands. The aim of this study was to investigate the diagnostic utility of CA6 in differentiating acinic cell carcinoma (AciCC) from its morphological mimic mammary analogue secretory carcinoma (MASC) of the salivary gland. METHODS AN...

journal_title：Histopathology

authors： Hsieh MS,Jeng YM,Jhuang YL,Chou YH,Lin CY

更新日期：2016-04-01 00:00:00

abstract：:S-100 positive epidermal dendritic cells were counted in skin biopsies from 48 Kveim tests and four known foreign-body reactions. Counts in histologically positive Kveim biopsies (mean 11.3 per 200 basal cells) were significantly higher than in either negative biopsies (5.1; P less than 0.001) or foreign-body reaction...

journal_title：Histopathology

authors： Shaw PA,Fletcher A

更新日期：1991-02-01 00:00:00

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a member of the lipocalin superfamily. Although its overexpression in various cancers has been reported, little is known about its expression and clinical significance in oral squamous cell carcinoma (OSCC). This study aimed to elucidate the clinical significanc...

journal_title：Histopathology

authors： Shinriki S,Jono H,Ueda M,Obayashi K,Nakamura T,Ota K,Ota T,Sueyoshi T,Guo J,Hayashi M,Hiraki A,Nakayama H,Yamashita S,Shinohara M,Ando Y

更新日期：2014-02-01 00:00:00

abstract：AIMS:Pulmonary sequelae, reported as chronic graft-versus-host disease (cGVHD), of haematopoietic stem cell transplantation (HSCT) include constrictive bronchiolitis obliterans (CBO), lymphocytic bronchiolitis (LB), and veno-occlusive disease (VOD); recently, pleuroparenchymal fibroelastosis (PPFE) has also been descri...

journal_title：Histopathology

authors： Takeuchi Y,Miyagawa-Hayashino A,Chen F,Kubo T,Handa T,Date H,Haga H

更新日期：2015-03-01 00:00:00

abstract：:The ultrastructure of stromal mononuclear cells and giant cells were studied in two cases of central giant cell granuloma of the jaws. The majority of stromal cells superficially resembled fibroblasts, but also contained intracytoplasmic myofilaments with electron dense bodies similar to smooth muscle cells. These cel...

journal_title：Histopathology

authors： El-Labban NG,Lee KW

更新日期：1983-11-01 00:00:00

abstract：AIMS:To address whether napsin A is useful for identifying metastatic adenocarcinomas of pulmonary origin. METHODS AND RESULTS:Fifty-four cases of adenocarcinoma that metastasized from the lungs to various sites and 1762 cases of carcinoma from various organs were immunostained for napsin A, TTF-1, CK7, CK20 and CDX2 ...

journal_title：Histopathology

authors： Kim MY,Go H,Koh J,Lee K,Min HS,Kim MA,Jeon YK,Lee HS,Moon KC,Park SY,Kim WH,Chung DH

更新日期：2014-08-01 00:00:00

abstract：:Two cases of tubulovillous adenoma and adjacent colonic mucosa were studied in which intestinal spirochaetosis had heavily colonized the non-neoplastic but not the neoplastic epithelium. Ultrastructural and histochemical studies were performed and we postulate that the reason for this disparity is the normal microvill...

journal_title：Histopathology

authors： Coyne JD,Curry A,Purnell P,Haboubi NY

更新日期：1995-10-01 00:00:00

abstract：AIMS:To evaluate the immunoexpression of cyclin A1 in pT1 urothelial carcinomas of the bladder (UC) from a cohort of patients treated by transurethral resection of the bladder (TURB), to determine its value in predicting tumour recurrence, tumour progression, or systemic metastases. METHODS AND RESULTS:Five tissue mic...

journal_title：Histopathology

authors： Munari E,Chaux A,Maldonado L,Compérat E,Varinot J,Bivalacqua TJ,Hoque MO,Netto GJ

更新日期：2015-01-01 00:00:00

abstract：AIMS:To assess MRP1 protein and MRP1 mRNA levels in gastric carcinomas and in non-neoplastic mucosa remote from the tumours. MRP1 gene expression may play a role in the complex pattern of chemoresistance present in gastric carcinomas. METHODS AND RESULTS:A total of 57 carcinomas and respective gastric tissues were inc...

journal_title：Histopathology

authors： Lacueva J,Perez-Ramos M,Soto JL,Oliver I,Andrada E,Medrano J,Perez-Vazquez T,Arroyo A,Carrato A,Ferragut JA,Calpena R

更新日期：2005-04-01 00:00:00

abstract：AIMS:NTRK gene rearranged sarcomas are emerging as a distinct class of sarcomas of particular importance in the era of targeted therapy. In this study we used Array Comparative Genomic Hybridisation (aCGH) to explore the cytogenetic profile of 6 adult soft tissue sarcomas harbouring NTRK gene fusions. METHODS AND RESU...

journal_title：Histopathology

authors： Vargas AC,Mesbah Ardakani N,Wong DD,Maclean FM,Kattampallil J,Boyle R,Santos L,Gill AJ

更新日期：2020-10-31 00:00:00

abstract：:The authors present a case of cholestatic jaundice which developed during total parenteral nutrition. The histology of the liver mimicked the picture of large bile duct obstruction. However, there was no duct obstruction and the symptoms regressed after the caloric input was reduced. At postmortem examination, the por...

journal_title：Histopathology

authors： Body JJ,Bleiberg H,Bron D,Maurage H,Bigirimana V,Heimann R

更新日期：1982-11-01 00:00:00

abstract：AIMS:Tyrosine kinase receptors Her2/neu and c-Met play an important role in breast cancer development and progression. Our aim was to determine the expression of c-Met, its ligand hepatocyte growth factor/scatter factor (HGF/SF) and Her2/neu in ductal carcinoma in situ (DCIS) lesions of the breast (n = 39) by two diffe...

journal_title：Histopathology

authors： Lindemann K,Resau J,Nährig J,Kort E,Leeser B,Annecke K,Welk A,Schäfer J,Vande Woude GF,Lengyel E,Harbeck N

更新日期：2007-07-01 00:00:00

abstract：AIMS:Helicobacter pylori has been claimed to be an important aetiological factor which raises the risk of mucosa-associated tissue lymphoid (MALT) lymphoma. However, some studies on gastric MALT lymphoma revealed a low rate of H. pylori infection suggesting that not all gastric lymphomas are related to H. pylori infect...

journal_title：Histopathology

authors： Bouzourene H,Haefliger T,Delacretaz F,Saraga E

更新日期：1999-02-01 00:00:00

abstract：AIMS:To investigate expression of nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) as a diagnostic tool to improve grading of dysplasia in Barrett's oesophagus patients. METHODS AND RESULTS:Immunostaining was analysed on a total of 192 biopsy samples of 22 Barrett's patients with no dysplasia...

journal_title：Histopathology

authors： van de Winkel A,van Zoest KP,van Dekken H,Moons LM,Kuipers EJ,van der Laan LJ

更新日期：2011-01-01 00:00:00

abstract：:The use of drugs for recreational purposes is widespread. The drugs used can be divided into groups including stimulants (cocaine, amphetamines, etc.), opiates and opioids (heroin, oxycodone, methadone, fentanyl, etc.), sedatives (benzodiazepines and related substances) and miscellaneous drugs, including ketamine and ...

journal_title：Histopathology

authors： Milroy CM,Parai JL

更新日期：2011-10-01 00:00:00

abstract：:Therapeutic use of oestrogens by males with carcinoma of the prostate leads to testicular atrophy with markedly reduced spermatogenesis after only 21 d (Oshima et al. 1974). Treatment for over a year results in paucity of germ cells, vacuolation of Sertoli cells and reduction in Leydig cells (Lu & Steinberger 1978, Sm...

journal_title：Histopathology

authors： Venizelos ID,Paradinas FJ

更新日期：1988-04-01 00:00:00

abstract：:Two cases of atypical juvenile polyposis are described in males of 9 months and 25 years-of-age. The first was associated with congenital megacolon and presented as juvenile polyps with features suggesting mild dysplasia. In the second case six histological lesions are found: I hyperplastic polyps; 2 juvenile polyps; ...

journal_title：Histopathology

authors： Grigioni WF,Alampi G,Martinelli G,Piccaluga A

更新日期：1981-07-01 00:00:00

abstract：AIMS:The great majority of ovarian clear cell carcinomas have a hepatocyte nuclear factor 1 homeobox B (HNF-1β)-positive and oestrogen receptor (ER)-negative immunoprofile. However, the pattern of HNF-1β and ER immunostaining in clear cell carcinomas of the endometrium and the usefulness of this panel in distinguishing...

journal_title：Histopathology

authors： Hoang LN,Han G,McConechy M,Lau S,Chow C,Gilks CB,Huntsman DG,Köbel M,Lee CH

更新日期：2014-03-01 00:00:00

abstract：AIMS:To investigate the clinicopathological and molecular characteristics, immunohistochemical profile and prognosis of pulmonary adenocarcinoma with a micropapillary pattern (MPPAC). METHODS AND RESULTS:Eight hundred and eighty-six pulmonary adenocarcinomas were divided into two groups: micropapillary pattern (MPP)-p...

journal_title：Histopathology

authors： Zhang J,Liang Z,Gao J,Luo Y,Liu T

更新日期：2011-12-01 00:00:00

abstract：AIMS:This study has compared the tissue expression of the p53 tumour suppressor protein and DNA repair proteins APE1, hMSH2 and ERCC1 in normal, dysplastic and malignant lip epithelium. METHODS AND RESULTS:Morphological analysis and immunohistochemistry were performed on archived specimens of normal lip mucosa (n=15),...

journal_title：Histopathology

authors： Souza LR,Fonseca-Silva T,Pereira CS,Santos EP,Lima LC,Carvalho HA,Gomez RS,Guimarães AL,De Paula AM

更新日期：2011-02-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is an unusual malignancy in that the tumour cells, the Hodgkin and Reed-Sternberg (HRS) cells, are a minor component of the tumour mass, the bulk of which is a mixed cellular infiltrate. There is compelling evidence that HRS cells are clonal B cells that have lost their B cell phenotype. Mature B...

journal_title：Histopathology

authors： Farrell K,Jarrett RF

更新日期：2011-01-01 00:00:00

abstract：AIMS:In T cells, protein kinase C (PKC) theta plays a major role in T-cell receptor (TCR)-mediated activation of a novel nuclear factor (NF)-kappaB pathway that involves phosphorylation of p65 at serine 536 (Pp65(Ser536)). Bcl-10 acts along the same pathway downstream of PKC theta to activate NF-kappaB. The aim was to ...

journal_title：Histopathology

authors： Briones J,Moga E,Espinosa I,Vergara C,Alvarez E,Villa J,Bordes R,Delgado J,Prat J,Sierra J

更新日期：2009-03-01 00:00:00

abstract：AIMS:Tissue microarray (TMA) is an efficient technique for analysis of molecular markers. Prospectively collected samples have been reported to give excellent concordance between TMA data and corresponding whole-sections. The aim was to evaluate the usefulness of TMA in a population-based cohort of 213 women with ducta...

journal_title：Histopathology

authors： Wärnberg F,Amini RM,Goldman M,Jirström K

更新日期：2008-12-01 00:00:00

abstract：:We report a case of oesophageal carcinosarcoma with prominent rhabdomyoblastic differentiation. Immunohistochemically, the rhabdomyblasts were mainly reactive to vimentin, cytokeratin, desmin, muscle-specific actin, myosin, and myoglobin, and were surrounded by laminin and type IV collagen-positive basement membranes....

journal_title：Histopathology

authors： Guarino M,Reale D,Micoli G,Forloni B

更新日期：1993-05-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：:The treatment of cancer has changed dramatically over the last decade, driven by increased understanding of the cancer genome, immune landscape, molecular alterations and aberrant pathways that drive cancer progression. Advances in molecular biology have led to the development of targeted agents, including monoclonal ...

journal_title：Histopathology

authors： Crusz SM,Miller RE

更新日期：2020-01-01 00:00:00

abstract：AIMS:Hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome is caused by germline mutations in the Fumarate hydratase (FH) gene. In young women, the syndrome often presents with symptomatic uterine leiomyomas, leading to myomectomy or hysterectomy. In this study, we aimed to investigate the incidence and muta...

journal_title：Histopathology

authors： Liu C,Dillon J,Beavis AL,Liu Y,Lombardo K,Fader AN,Hung CF,Wu TC,Vang R,Garcia JE,Xing D

更新日期：2020-02-01 00:00:00