Cyclin A1 expression predicts progression in pT1 urothelial carcinoma of bladder: a tissue microarray study of 149 patients treated by transurethral resection.

abstract：AIMS:Pathology specimens often contain important margins that must be identified from gross examination of specimens through to microscopic examination. Commonly, unique colours of tissue-marking dye (TMD) are applied to each margin, which facilitates both macroscopic and microscopic identification. Various techniques ...

journal_title：Histopathology

authors： Williams AS,Dakin Haché K

更新日期：2014-05-01 00:00:00

abstract：:The use of drugs for recreational purposes is widespread. The drugs used can be divided into groups including stimulants (cocaine, amphetamines, etc.), opiates and opioids (heroin, oxycodone, methadone, fentanyl, etc.), sedatives (benzodiazepines and related substances) and miscellaneous drugs, including ketamine and ...

journal_title：Histopathology

authors： Milroy CM,Parai JL

更新日期：2011-10-01 00:00:00

abstract：:There are many significant differences, but also considerable overlap between the quantitative histopathological features of mild and marked atypical endometrial hyperplasias and well and moderately differentiated carcinomas, thus preventing its application to individual patient care. To try to overcome this problem, ...

journal_title：Histopathology

authors： Baak JP,Kurver PH,Overdiep SH,Delemarre JF,Boon ME,Lindeman J,Diegenbach PC

更新日期：1981-11-01 00:00:00

abstract：AIMS:Genome-wide next-generation sequencing has revealed several driver mutations and has allowed the establishment of a molecular taxonomy of gastric cancer. However, there are few detailed studies on the mutational spectrum of poorly cohesive gastric carcinoma. Thus, this study aim to investigate its mutation profile...

journal_title：Histopathology

authors： Kwon CH,Kim YK,Lee S,Kim A,Park HJ,Choi Y,Won YJ,Park DY,Lauwers GY

更新日期：2018-03-01 00:00:00

abstract：AIMS:Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland carcinomas. Epidermal growth factor receptor (EGFR) signalling pathway gene mutations are important in predicting a patient's prognosis, selecting molecularly targeted drugs and estimating the efficacy of a molecular therapy. However, their si...

journal_title：Histopathology

authors： Morita M,Murase T,Okumura Y,Ueda K,Sakamoto Y,Masaki A,Kawakita D,Tada Y,Nibu KI,Shibuya Y,Inagaki H

更新日期：2020-06-01 00:00:00

abstract：:The aim of this study was to document the patterns of cytoplasmic Ig heavy and light chain expression in reactive lymphoid tissue, using single and double immunoenzymatic labelling techniques. This investigation was undertaken, firstly, to provide information on whether the normal counterparts of high grade lymphoma c...

journal_title：Histopathology

authors： Morris HB,Mason DY,Stein H,Lennert K

更新日期：1983-11-01 00:00:00

abstract：:Lobular carcinoma in situ and atypical lobular hyperplasia were first described over 50 years ago. Despite this long incubation period, the biological nature of the lesions remains controversial. They are generally regarded as 'risk indicators' of invasive cancer rather than true precursor lesions. When first describe...

journal_title：Histopathology

authors： Lishman SC,Lakhani SR

更新日期：1999-09-01 00:00:00

abstract：AIMS:Recent analyses have suggested that Hodgkin's or Reed-Sternberg (HRS) cells in most cases of classic Hodgkin's disease are derived from germinal centre B-cells. However, there is controversy over which B-cell antigens are expressed in HRS cells. METHODS AND RESULTS:We studied 51 cases of classic Hodgkin's disease...

journal_title：Histopathology

authors： Watanabe K,Yamashita Y,Nakayama A,Hasegawa Y,Kojima H,Nagasawa T,Mori N

更新日期：2000-04-01 00:00:00

abstract：AIMS:To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic liposarcoma. Pleomorphic liposarcoma is a very rare variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts showing peculiar epithelial-like features that can be confu...

journal_title：Histopathology

authors： De Cecco L,Gariboldi M,Reid JF,Lagonigro MS,Tamborini E,Albertini V,Staurengo S,Pilotti S,Pierotti MA

更新日期：2005-03-01 00:00:00

abstract：AIMS:The third edition of the World Health Organization (WHO) classification of lung tumours has been published and is expected to become the standard nomenclature. The aim of this study was to assess the usability and prognostic significance of the WHO classification in comparison with other recent classifications. M...

journal_title：Histopathology

authors： Aida S,Shimazaki H,Sato K,Sato M,Deguchi H,Ozeki Y,Tamai S

更新日期：2004-11-01 00:00:00

abstract：:This study demonstrates the presence of three antigens in glandular metaplasia occurring in patients with cholecystitis and cholelithiasis: specifically carcinoembryonic antigen (CEA), large intestinal mucin antigen (LIMA) and small intestinal mucin antigen (SIMA). These antigens could not be detected in normal gall b...

journal_title：Histopathology

authors： De Boer WG,Ma J,Rees JW,Nayman J

更新日期：1981-05-01 00:00:00

abstract：AIMS:Neuropilin-2 is a coreceptor for vascular endothelial growth factor family members. Blockade of neuropilin-2 is able to suppress lymphogenous metastasis in preclinical models. The aim of this study was to validate a protocol for the evaluation of neuropilin-2 protein expression in situ, by comparison with in-situ ...

journal_title：Histopathology

authors： Jubb AM,Sa SM,Ratti N,Strickland LA,Schmidt M,Callahan CA,Koeppen H

更新日期：2012-09-01 00:00:00

abstract：AIMS:To characterize the clinicopathological features and biological potential of a group of soft tissue lesions with morphology intermediate between intramuscular myxoma and low-grade myxofibrosarcoma. METHODS AND RESULTS:Thirty-eight lesions in 37 patients were retrieved from the authors' consultation files. Clinica...

journal_title：Histopathology

authors： van Roggen JF,McMenamin ME,Fletcher CD

更新日期：2001-09-01 00:00:00

abstract：:Ultrastructural appearances of a small intestinal inflammatory fibroid polyp are reported. There is a vascular scaffolding, with interstices which contain regular and fibrous long-spacing type collagen, condensed lamellar basement membrane fibroblasts, basophils, some eosinophils and histiocytes. In addition other cel...

journal_title：Histopathology

authors： Williams RM

更新日期：1981-03-01 00:00:00

abstract：:The aim of this study is to provide a long-term follow-up of patients with tubular carcinoma and to investigate whether the separation of the mixed type of tubular carcinoma, tubular component more than 75%, from invasive ductal carcinoma with a major tubular component (ductal carcinoma MTC), tubular component 50 to 7...

journal_title：Histopathology

authors： Carstens PH,Greenberg RA,Francis D,Lyon H

更新日期：1985-03-01 00:00:00

abstract：AIMS:In skull base chordoma, c-MET expression has been reported to correlate with younger patient age and favourable prognosis; however, it also contributes to tumour invasiveness, especially in recurrent lesions, suggesting variable roles for c-MET according to clinical status. The aim of this study was to investigate...

journal_title：Histopathology

authors： Naka T,Boltze C,Samii A,Samii M,Herold C,Ostertag H,Iwamoto Y,Oda Y,Tsuneyoshi M,Kuester D,Roessner A

更新日期：2009-04-01 00:00:00

abstract：AIMS:To evaluate whether there is a correlation between the subcellular localization of maspin and the histological, molecular and biological features of pulmonary adenocarcinoma, particularly addressing the hypothesis that the tumour inhibitor properties of maspin may be linked to a nuclear, compared with a combined n...

journal_title：Histopathology

authors： Frey A,Soubani AO,Adam AK,Sheng S,Pass HI,Lonardo F

更新日期：2009-04-01 00:00:00

abstract：AIMS:This study aimed to assess the feasibility of using virtual slides to create 3D histopathological reconstructions to aid in the study of the biology of DCIS. METHODS:Four μm thick serial sections of formalin fixed paraffin embedded tissue from three cases were cut and mounted onto glass slides, stained with haema...

journal_title：Histopathology

authors： Booth ME,Treanor D,Roberts N,Magee DR,Speirs V,Hanby AM

更新日期：2015-06-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：AIMS:A variety of histological variants of thymic carcinoid tumour have been described. A rare case of pigmented spindle cell carcinoid tumour of the thymus is documented and compared with the reported cases of thymic pigmented carcinoid tumour in the literature, with a discussion of the differential diagnosis of spind...

journal_title：Histopathology

authors： Kuo TT

更新日期：2002-02-01 00:00:00

abstract：AIMS:We tried to improve the evaluation of E-cadherin immunostaining in paraffin sections, to distinguish the less aggressive variants of ductal infiltrating breast cancer from other variants. METHODS AND RESULTS:The method graded the membrane staining and estimated the fraction of area of cancer tissue stained at the...

journal_title：Histopathology

authors： Elzagheid A,Kuopio T,Ilmen M,Collan Y

更新日期：2002-08-01 00:00:00

abstract：:Chromosomal rearrangements resulting in the fusion of coding parts from two genes or in the exchange of regulatory sequences are present in approximately 20% of all human neoplasms. More than 1000 such gene fusions have now been described, with close to 100 of them in soft tissue tumours. Although little is still know...

journal_title：Histopathology

authors： Mertens F,Tayebwa J

更新日期：2014-01-01 00:00:00

abstract：AIMS:Pyruvate kinase M2 (PKM2) and lactate dehydrogenase 5 (LDH5) are two metabolic and oncogenic markers of cancer. In this study, we sought to investigate their expression patterns and prognostic value in tongue squamous cell carcinoma (TSCC). METHODS AND RESULTS:The expression and subcellular localization of PKM2 a...

journal_title：Histopathology

authors： Yuan C,Li Z,Wang Y,Qi B,Zhang W,Ye J,Wu H,Jiang H,Song LN,Yang J,Cheng J

更新日期：2014-11-01 00:00:00

abstract：:Biopsy and autopsy material from the urinary bladder was studied using PAS and PAS-D techniques to identify glycogen and neutral mucins, the alcian blue/high iron diamine method to distinguish sialo- and sulphamucins and the PB/KOH/PAS technique to localize O-acylated sialomucins. All of 10 examples of normal urotheli...

journal_title：Histopathology

authors： Newbould M,McWilliam LJ

更新日期：1990-09-01 00:00:00

abstract：:Two cases of atypical juvenile polyposis are described in males of 9 months and 25 years-of-age. The first was associated with congenital megacolon and presented as juvenile polyps with features suggesting mild dysplasia. In the second case six histological lesions are found: I hyperplastic polyps; 2 juvenile polyps; ...

journal_title：Histopathology

authors： Grigioni WF,Alampi G,Martinelli G,Piccaluga A

更新日期：1981-07-01 00:00:00

abstract：:A series of 115 consecutive, non-ulcerous, dyspeptic patients were examined for Helicobacter pylori (H. pylori) colonization in the gastric antral and/or body mucosa using Giemsa staining. Findings were correlated with the presence and degree of activity of superficial gastritis, deep gastritis, atrophic gastritis and...

journal_title：Histopathology

authors： Rugge M,Di Mario F,Cassaro M,Baffa R,Farinati F,Rubio J Jr,Ninfo V

更新日期：1993-01-01 00:00:00

abstract：AIMS:Although many immunohistochemical (IHC) cancer biomarkers have been identified, very few have translated into routine clinical practice, primarily because of technical and observational inconsistencies between studies. However, despite the obvious need to address such variability, very few studies have done so. M...

journal_title：Histopathology

authors： Lawrie CH,Ballabio E,Soilleux E,Sington J,Hatton CS,Dirnhofer S,Tzankov A

更新日期：2012-07-01 00:00:00

abstract：AIMS:To survey current European practices in handling and reporting of radical prostatectomy (RP) specimens. METHODS AND RESULTS:A European Network of Uropathology (ENUP) was organized for the dissemination of information, survey studies and research collaborations. Contact data of uropathologists were collected from ...

journal_title：Histopathology

authors： Egevad L,Algaba F,Berney DM,Boccon-Gibod L,Griffiths DF,Lopez-Beltran A,Mikuz G,Varma M,Montironi R,European Network of Uropathology.

更新日期：2008-09-01 00:00:00

abstract：:The clinical and pathological features of six cases of a hitherto undescribed lesion of the breast are reported for which the term 'microglandular adenosis' has been proposed. This is characterized by a proliferation of small uniform glands lined by epithelial cells without apparent myoepithelial cells and with usuall...

journal_title：Histopathology

authors： Clement PB,Azzopardi JG

更新日期：1983-03-01 00:00:00

abstract：AIMS:To document the clinical, light microscopic, immunohistochemical and ultrastructural features of four cases of extra-orbital giant cell angiofibromas. METHODS AND RESULTS:Sections of formalin-fixed paraffin-embedded specimens were studied by haematoxylin and eosin, reticulin and immunohistochemical stains. Electr...

journal_title：Histopathology

authors： Thomas R,Banerjee SS,Eyden BP,Shanks JH,Bisset DL,Hunt R,Byers RJ,Oogarah P,Harris M

更新日期：2001-10-01 00:00:00