Three-dimensional reconstruction of ductal carcinoma in situ with virtual slides.

abstract：AIMS:The study was undertaken to demonstrate wild-type p53 in normal paraffin-embedded tissues using two widely used antibodies, DO7 and 1801 and two different antigen retrieval buffer systems. METHODS AND RESULTS:Formalin-fixed paraffin-embedded normal tissue samples were obtained from the archives of the John Radcli...

journal_title：Histopathology

authors： Pillai G,Roberts H,Gatter K,Pezzella F

更新日期：2003-01-01 00:00:00

abstract：AIM:We describe the unusual association of fallopian tubal prolapse and herpetic infection, an occurrence not previously reported to our knowledge. METHODS AND RESULTS:A 37-year-old woman presented with a small polypoid mass of the vaginal vault, 3 months after abdominal hysterectomy and abdominoplasty. The vaginal ma...

journal_title：Histopathology

authors： Lefrancq T,Orain I,Michalak S,Hourseau M,Fetissof F

更新日期：1999-06-01 00:00:00

abstract：AIMS:There is increasing evidence of Gleason score (GS) drift in prostatic core biopsies during the last two decades. The ProtecT study is a randomized controlled study and provides an excellent cohort to study the effect of time, prostate-specific antigen (PSA) level, perineural invasion, tumour length and age on GS. ...

journal_title：Histopathology

authors： Oxley J,Simpkin A,Goepel J,Varma M,Griffiths D,Grigor K,Mayer N,Warren A,Deshmukh N,Bhattarai S,Dormer J,Hounsome L,Adamczyk LA,Metcalfe C,Lane JA,Davis M,Donovan JL,Neal DE,Hamdy FC,Robinson MC,ProtecT Study Grou

更新日期：2015-02-01 00:00:00

abstract：AIMS:Histological grade is one of the most important prognostic factors in breast carcinomas, but poorly differentiated neoplasms still have quite heterogeneous biological behaviour, since they can be genetically classified as basal-like, HER2+ or even luminal. The aim was to analyse the frequency of oestrogen receptor...

journal_title：Histopathology

authors： Fernandes RC,Bevilacqua JL,Soares IC,Siqueira SA,Pires L,Hegg R,Carvalho FM

更新日期：2009-09-01 00:00:00

abstract：:The post-transplant lymphoproliferative disorders represent a spectrum of life-threatening, generally Epstein-Barr virus-associated lymphoid proliferations which occur in the setting of exogenous immunosuppression following organ transplantation. Histopathological, phenotypic, genotypic and Epstein-Barr virus studies ...

journal_title：Histopathology

authors： Swerdlow SH

更新日期：1992-05-01 00:00:00

abstract：AIMS:Pulmonary artery (PA) dissection is a rare event which usually occurs in patients with underlying pulmonary hypertension. We describe two patients who developed PA dissection without pre-existing pulmonary hypertension and present an extensive review of the literature. METHODS AND RESULTS:In the first patient (a ...

journal_title：Histopathology

authors： Inayama Y,Nakatani Y,Kitamura H

更新日期：2001-05-01 00:00:00

abstract：:The aim of this study was to document the patterns of cytoplasmic Ig heavy and light chain expression in reactive lymphoid tissue, using single and double immunoenzymatic labelling techniques. This investigation was undertaken, firstly, to provide information on whether the normal counterparts of high grade lymphoma c...

journal_title：Histopathology

authors： Morris HB,Mason DY,Stein H,Lennert K

更新日期：1983-11-01 00:00:00

abstract：:Some antigenic determinants can be preserved in tissues after plastic embedding. In the present study liver tissue was fixed with glutaraldehyde or paraformaldehyde, dehydrated with ethanol and toluene and embedded in araldite which was then polymerized at 37 degrees C. Immunofluorescence was performed on semi-thin se...

journal_title：Histopathology

authors： Scotto J

更新日期：1977-09-01 00:00:00

abstract：AIMS:Despite increasing interest in the recently established immunoglobulin 4-related disease (IgG4-RD), its pathogenesis and aetiology remain largely unclear. Characteristic histopathological features are one of the key elements of diagnosis, including 'storiform' fibrosis, obliterative phlebitis, increased lymphoplas...

journal_title：Histopathology

authors： Nowak V,Agaimy A,Kristiansen G,Gütgemann I

更新日期：2020-01-01 00:00:00

abstract：:Alongside histomorphology and immunohistochemistry, molecular pathology is now established as one of the cornerstones in the tissue diagnosis of bone tumours. We describe the principal molecular pathological techniques employed, and each of the bone tumour entities where their identified characteristic molecular patho...

journal_title：Histopathology

authors： Puls F,Niblett AJ,Mangham DC

更新日期：2014-03-01 00:00:00

abstract：AIMS:Whilst parenchymal changes in pulmonary sequestrations are well described, there are comparatively little data on associated vascular changes and their extent. The aim of this study was to retrospectively review morphological changes within sequestrations, concentrating on vascular changes and associations with cl...

journal_title：Histopathology

authors： Desai S,Dusmet M,Ladas G,Pomplun S,Padley SP,Griffin N,Badreddine J,Goldstraw P,Nicholson AG

更新日期：2010-07-01 00:00:00

abstract：AIMS:We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF). METHODS AND RESULTS:A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial in...

journal_title：Histopathology

authors： Serrano R,Martínez MA,Andrés A,Morales JM,Samartin R

更新日期：1998-08-01 00:00:00

abstract：:Identical adolescent Negro twins presented with multiple bilateral breast adenomata. There were three pure tubular adenomata, one mixed tubular and fibroadenoma, four glandular fibroadenomata and one typical intracanalicular fibroadenoma. Tubular adenomata are exceedingly rare and this report adds a further three to t...

journal_title：Histopathology

authors： Morris JA,Kelly JF

更新日期：1982-09-01 00:00:00

abstract：:Germ cell tumours may imitate various structures of the developing embryo and foetus. Certain structures have, however, very rarely or never been observed in these tumours. Thus the presence of hepatic tissue in testicular germ cell tumours has not been reported. In a series of 37 non-seminomatous testicular tumours s...

journal_title：Histopathology

authors： Jacobsen GK,Jacobsen M

更新日期：1983-07-01 00:00:00

abstract：:The aim of this study was to examine the immunohistochemical expression of p53 and bcl-2 in Kaposi's sarcoma and relate this with proliferation index (as measured by MIB-1 staining) and clinicopathological subtypes. Twenty formalin-fixed, paraffin-embedded cases of Kaposi's sarcoma were stained with commercially avail...

journal_title：Histopathology

authors： Dada MA,Chetty R,Biddolph SC,Schneider JW,Gatter KC

更新日期：1996-08-01 00:00:00

abstract：AIMS:Alterations in the expression of several long non-coding RNAs (lncRNAs) have been found in primary nasopharyngeal carcinoma (NPC). However, the effect of lncRNA expression on primary NPC as well as the molecular mechanism of lncRNA remains vague. This study was to identify differentially expressed lncRNAs involved...

journal_title：Histopathology

authors： Yang QQ,Deng YF

更新日期：2015-06-01 00:00:00

abstract：AIMS:To test the effectiveness of a teaching resource (a decision tree with diagnostic criteria based on published literature) in improving the proficiency of Gleason grading of prostatic cancer by general pathologists. METHODS:A decision tree with diagnostic criteria was developed by a panel of urological pathologist...

journal_title：Histopathology

authors： Griffiths DF,Melia J,McWilliam LJ,Ball RY,Grigor K,Harnden P,Jarmulowicz M,Montironi R,Moseley R,Waller M,Moss S,Parkinson MC

更新日期：2006-05-01 00:00:00

abstract：AIMS:HER2 testing of invasive breast cancer by in-situ hybridization guides therapy decisions. Probing HER2 and centromere of chromosome 17 (cen17) simultaneously is supposed to reveal both a potential HER2 gene amplification and polysomy 17. However, a considerable number of breast cancer patients with quasi polysomy ...

journal_title：Histopathology

authors： Holzschuh MA,Czyz Z,Hauke S,Inwald EC,Polzer B,Brockhoff G

更新日期：2017-10-01 00:00:00

abstract：:A retrospective histopathological study was undertaken to determine the prevalence of mucin filled ducts and their associated mucinous proliferation in 962 breast cancers and 335 benign lesions. A total of 38 (3%) cases with mucin filled ducts was identified and 27 (2%) of these showed mucin extravasation into the adj...

journal_title：Histopathology

authors： Chinyama CN,Davies JD

更新日期：1996-12-01 00:00:00

abstract：:Anaplastic choroid plexus carcinoma is a tumour with a predilection for the posterior fossa of infants and can be difficult to distinguish histologically from medulloblastoma without the aid of immunocytochemistry using a panel of antibodies. Of a series of 17 choroid plexus carcinomas (five of which were classed as m...

journal_title：Histopathology

authors： Newbould MJ,Kelsey AM,Arango JC,Ironside JW,Birch J

更新日期：1995-02-01 00:00:00

abstract：:An increased incidence of non-Hodgkin's lymphoma is seen in patients with immunodeficiency from any cause. The majority of these are high grade B-cell lymphoma and most are associated with the Epstein-Barr virus (EBV). In post-transplant lymphoma/lymphoproliferative disorders the tumour may regress following reduction...

journal_title：Histopathology

authors： Wotherspoon AC,Diss TC,Pan L,Singh N,Whelan J,Isaacson PG

更新日期：1996-02-01 00:00:00

abstract：:A variety of cytomorphological features, architectural patterns and stromal changes may be observed in malignant melanomas. Hence, melanomas may mimic carcinomas, sarcomas, benign stromal tumours, lymphomas, plasmacytomas and germ cell tumours. Melanomas may be composed of large pleomorphic cells, small cells, spindle...

journal_title：Histopathology

authors： Banerjee SS,Harris M

更新日期：2000-05-01 00:00:00

abstract：:Fifteen cases of non-Hodgkin's lymphoma of the anterior mediastinum are reported. In the first group of four, fresh tissue was available and immunohistochemical studies demonstrated their B-cell origin, with monotypic immunoglobulin production in two. Only fixed tissue was available in the second group of 11 patients....

journal_title：Histopathology

authors： Addis BJ,Isaacson PG

更新日期：1986-04-01 00:00:00

abstract：AIM:Primary cutaneous neuroendocrine carcinoma, or Merkel cell carcinoma (MCC), cannot be distinguished morphologically from small-cell neuroendocrine carcinomas (SmCC) from other sites. Immunohistochemistry is required to confirm cutaneous origin, and is also used for detection of sentinel lymph node (SLN) metastases ...

journal_title：Histopathology

authors： Stanoszek LM,Chan MP,Palanisamy N,Carskadon S,Siddiqui J,Patel RM,Harms KL,Lowe L,Fullen DR,Harms PW

更新日期：2019-02-01 00:00:00

abstract：AIMS:An increased risk of adenocarcinoma of the oesophagus has been demonstrated in patients with long segments of Barrett's mucosa. The risk of cancer associated with short segments of metaplasia of the oesophagogastric junction is not known. METHODS AND RESULTS:We report a case of early adenocarcinoma of the oesopha...

journal_title：Histopathology

authors： Santacroce CM,Fléjou JF

更新日期：1997-07-01 00:00:00

abstract：:In the course of running two clinical trials between 1966 and 1985, data became available for 1315 patients, 713 in the first trial and 602 patients in the second trial, which has allowed comparison between histological findings in laryngeal and hypopharyngeal carcinoma, the observed survival and the tumour-free rates...

journal_title：Histopathology

authors： Wiernik G,Millard PR,Haybittle JL

更新日期：1991-11-01 00:00:00

abstract：:In recent years the interaction between tumour cells and the surrounding extracellular matrix in the process of tumour development, invasion and metastasis has been a focus of interest. We studied frozen sections of nine naevocellular naevi (junctional, compound and intradermal), 40 dysplastic naevi, six pagetoid in s...

journal_title：Histopathology

authors： Van Duinen CM,Fleuren GJ,Bruijn JA

更新日期：1994-01-01 00:00:00

abstract：:Chromosomal rearrangements resulting in the fusion of coding parts from two genes or in the exchange of regulatory sequences are present in approximately 20% of all human neoplasms. More than 1000 such gene fusions have now been described, with close to 100 of them in soft tissue tumours. Although little is still know...

journal_title：Histopathology

authors： Mertens F,Tayebwa J

更新日期：2014-01-01 00:00:00

abstract：:A study was made of the cells forming the crescents in human crescentic glomerulonephritis. The investigation was performed using a panel of antibodies with immunoperoxidase techniques in formalin fixed, paraffin embedded renal biopsy material. Some of the cells of glomerular crescents were found to contain cytokerati...

journal_title：Histopathology

authors： Harrison DJ,MacDonald MK

更新日期：1986-09-01 00:00:00

abstract：AIMS:Mesenchyme forkhead 1 (FoxC2) is an epithelial-mesenchymal transition (EMT)-inducing factor. Previous studies have demonstrated that FoxC2 binds directly to the promoter region of p120-catenin (p120ctn). The aim of this study was to investigate the clinical significance of FoxC2 expression and the inter-relationsh...

journal_title：Histopathology

authors： Zhu JL,Song YX,Wang ZN,Gao P,Wang MX,Dong YL,Xing CZ,Xu HM

更新日期：2013-06-01 00:00:00