Possible liver cell differentiation in testicular germ cell tumours.

abstract：AIMS:Malignant mesothelioma is a highly aggressive cancer that is usually diagnosed at advanced stages; thus, highly sensitive and specific markers are necessary for its early definitive diagnosis. The aim of this study was to evaluate the diagnostic utility and prognostic significance of BAP1 and EZH2 in malignant mes...

journal_title：Histopathology

authors： Shinozaki-Ushiku A,Ushiku T,Morita S,Anraku M,Nakajima J,Fukayama M

更新日期：2017-04-01 00:00:00

abstract：:We report an example of what we believe to be an adenocarcinoma of the appendix testis. This very rare neoplasm arose in a patient on long term treatment with oestrogens which may be implicated as an aetiological factor. ...

journal_title：Histopathology

authors： Kernohan NM,Coutts AG,Best PV

更新日期：1990-08-01 00:00:00

abstract：AIMS:Perineural invasion (PNI) by prostatic adenocarcinoma is debated as a prognostic parameter. This study investigates the prognostic predictive value of PNI in a series of patients with locally advanced prostate cancer treated with radiotherapy and androgen deprivation using 10 years outcome data from the TROG 03.04...

journal_title：Histopathology

authors： Delahunt B,Murray JD,Steigler A,Atkinson C,Christie D,Duchesne G,Egevad L,Joseph D,Matthews J,Oldmeadow C,Samaratunga H,Spry NA,Srigley JR,Hondermarck H,Denham JW

更新日期：2020-08-01 00:00:00

abstract：:Chronic inflammatory cells are a recognized component of atherosclerotic plaques at all stages of development. As adhesion molecules play a fundamental role in inflammatory processes, we have carried out an immunohistochemical investigation of the distribution of endothelial leucocyte adhesion molecule-1 (ELAM-1)*, in...

journal_title：Histopathology

authors： Wood KM,Cadogan MD,Ramshaw AL,Parums DV

更新日期：1993-05-01 00:00:00

abstract：:The recognition of recurrent genetic alterations in specific tumour types has provided the basis for the reclassification of certain soft tissue neoplasms, and molecular analysis of patient material has the potential to provide both diagnostic and prognostic information. In this review, we evaluate the role of molecul...

journal_title：Histopathology

authors： Pfeifer JD,Hill DA,O'Sullivan MJ,Dehner LP

更新日期：2000-12-01 00:00:00

abstract：:The new World Health Organization (WHO) classification of soft tissue tumours was published in early 2013, almost 11 years after the previous edition. While the number of newly recognized entities included for the first time is fewer than that in 2002, there have instead been substantial steps forward in molecular gen...

journal_title：Histopathology

authors： Fletcher CD

更新日期：2014-01-01 00:00:00

abstract：:Biopsy and autopsy material from the urinary bladder was studied using PAS and PAS-D techniques to identify glycogen and neutral mucins, the alcian blue/high iron diamine method to distinguish sialo- and sulphamucins and the PB/KOH/PAS technique to localize O-acylated sialomucins. All of 10 examples of normal urotheli...

journal_title：Histopathology

authors： Newbould M,McWilliam LJ

更新日期：1990-09-01 00:00:00

abstract：:During the last decade pathology has benefited from the rapid progress of image digitizing technology. The improvement in this technology had led to the creation of slide scanners which are able to produce whole slide images (WSI) which can be explored by image viewers in a way comparable to the conventional microscop...

journal_title：Histopathology

authors： Al-Janabi S,Huisman A,Van Diest PJ

更新日期：2012-07-01 00:00:00

abstract：AIMS:Serum amyloid A is an acute phase reactant that is produced by hepatocytes in response to either inflammatory or neoplastic conditions. Because inflammatory adenomas produce this protein, serum amyloid A immunohistochemistry has been used in the evaluation of hepatocellular neoplasms. However, studies evaluating t...

journal_title：Histopathology

authors： Piotti KC,Yantiss RK,Chen Z,Jessurun J

更新日期：2016-12-01 00:00:00

abstract：AIMS:Helicobacter pylori has been claimed to be an important aetiological factor which raises the risk of mucosa-associated tissue lymphoid (MALT) lymphoma. However, some studies on gastric MALT lymphoma revealed a low rate of H. pylori infection suggesting that not all gastric lymphomas are related to H. pylori infect...

journal_title：Histopathology

authors： Bouzourene H,Haefliger T,Delacretaz F,Saraga E

更新日期：1999-02-01 00:00:00

abstract：:The morphology, phenotype, genotype and clinical behaviour of four cases of mantle cell lymphoma (centrocytic lymphoma) presenting primarily in mucosa (two gastric, one in large bowel and one tonsillar) are reviewed. Their relationship with the broader group of mantle cell and mucosa-associated lymphoid tissue (MALT) ...

journal_title：Histopathology

authors： Fraga M,Lloret E,Sanchez-Verde L,Orradre JL,Campo E,Bosch F,Piris MA

更新日期：1995-05-01 00:00:00

abstract：:We report an unusual and possibly unique example of cerebral ganglioglioma with an anaplastic oligodendroglial component. The latter was documented on both morphological and immunohistochemical grounds. Immunohistochemically, the anaplastic cells were strongly positive with the monoclonal antibody anti-Leu-7, while th...

journal_title：Histopathology

authors： Allegranza A,Pileri S,Frank G,Ferracini R

更新日期：1990-11-01 00:00:00

abstract：:A case is reported of nodular lymphocyte predominant Hodgkin's disease arising 13 years after the removal of a lymph node from the same site which showed marked progressive transformation of germinal centres. The morphological evidence for a histogenetic relationship between the two conditions is presented and discuss...

journal_title：Histopathology

authors： Crossley B,Heryet A,Gatter KC

更新日期：1987-06-01 00:00:00

abstract：:In this study breast tissue that contained ultrastructural dense core granules has been examined from 24 patients. The possible neuroendocrine characteristics of the granules were studied using the uranaffin reaction and an ultrastructural argyrophil stain. The tissue included 15 breast carcinomas and nine benign samp...

journal_title：Histopathology

authors： Hopkinson HE,Battersby S,Anderson TJ

更新日期：1987-11-01 00:00:00

abstract：AIMS:Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in gallbladder tissues. I...

journal_title：Histopathology

authors： Espinoza JA,Riquelme I,Sagredo EA,Rosa L,García P,Bizama C,Apud-Bell M,Leal P,Weber H,Benavente F,Vargas S,Romero D,Kalergis AM,Roa JC

更新日期：2019-03-01 00:00:00

abstract：:Granular cell tumours rarely involve the lower respiratory tract. We report eight cases surgically resected at our institution. There were four females and four males, aged between 18 to 56 years (mean 40). One tumour associated with a peripheral lung adenocarcinoma was asymptomatic. The other lesions presented with o...

journal_title：Histopathology

authors： Thomas de Montpréville V,Dulmet EM

更新日期：1995-09-01 00:00:00

abstract：:Five antibodies, MT1 (CD43), UCHL1 (CD45RO), OPD4, poly-CD3 and beta F1, were assessed for their reactivity with 50 archival cases of T-cell lymphoma in formalin-fixed paraffin-embedded tissue. All cases had been previously characterized as T-cell lymphomas, and the histological types included 14 cases of small cerebr...

journal_title：Histopathology

authors： Cabeçadas JM,Isaacson PG

更新日期：1991-11-01 00:00:00

abstract：AIM:Achalasia is a disease of the oesophagus characterized by increased lower oesophageal sphincter (LOS) tone, absence of LOS relaxation with swallowing and aperistalsis of the body of the oesophagus. The aetiology and pathogenesis of idiopathic achalasia is still controversial. METHODS AND RESULTS:We examined 16 oes...

journal_title：Histopathology

authors： Raymond L,Lach B,Shamji FM

更新日期：1999-11-01 00:00:00

abstract：:Nineteen out of 121 consecutive cardiac biopsies from 107 patients were found to contain amyloid deposits on routine Congo red screening. Seventeen were left atrial appendages removed during mitral valvotomy for chronic rheumatic mitral valve disease while the remaining two were right atrial appendages excised during ...

journal_title：Histopathology

authors： Looi LM

更新日期：1981-11-01 00:00:00

abstract：AIMS:Diffuse large B-cell lymphoma (DLBCL) usually proliferates effacing lymph follicles. In occasional cases, tumour cells show an interfollicular pattern of proliferation preserving lymph follicles. The aim was to analyse clinicopathological findings in DLBCL showing an interfollicular pattern of proliferation to det...

journal_title：Histopathology

authors： Yamauchi A,Ikeda J,Nakamichi I,Kohara M,Fukuhara S,Hino M,Kanakura Y,Ogawa H,Sugiyama H,Kanamaru A,Aozasa K,Osaka Lymphoma Study Group.

更新日期：2008-05-01 00:00:00

abstract：AIMS:Carbonic anhydrase VI (CA6) is present in serous acinar cells of human salivary glands. The aim of this study was to investigate the diagnostic utility of CA6 in differentiating acinic cell carcinoma (AciCC) from its morphological mimic mammary analogue secretory carcinoma (MASC) of the salivary gland. METHODS AN...

journal_title：Histopathology

authors： Hsieh MS,Jeng YM,Jhuang YL,Chou YH,Lin CY

更新日期：2016-04-01 00:00:00

abstract：:The authors present a case of cholestatic jaundice which developed during total parenteral nutrition. The histology of the liver mimicked the picture of large bile duct obstruction. However, there was no duct obstruction and the symptoms regressed after the caloric input was reduced. At postmortem examination, the por...

journal_title：Histopathology

authors： Body JJ,Bleiberg H,Bron D,Maurage H,Bigirimana V,Heimann R

更新日期：1982-11-01 00:00:00

abstract：:The ultrastructure of stromal mononuclear cells and giant cells were studied in two cases of central giant cell granuloma of the jaws. The majority of stromal cells superficially resembled fibroblasts, but also contained intracytoplasmic myofilaments with electron dense bodies similar to smooth muscle cells. These cel...

journal_title：Histopathology

authors： El-Labban NG,Lee KW

更新日期：1983-11-01 00:00:00

abstract：AIMS:Survivin, a newly discovered member of the inhibitor of apoptosis protein family, is suggested to be involved in liver carcinogenesis. The aim was to investigate the clinical significance of survivin expression in resected hepatocellular carcinoma (HCC) and paired adjacent non-tumour tissue. METHODS AND RESULTS:I...

journal_title：Histopathology

authors： Chau GY,Lee AF,Tsay SH,Ke YR,Kao HL,Wong FH,Tsou AP,Chau YP

更新日期：2007-08-01 00:00:00

abstract：AIMS:Tissue microarray (TMA) is an efficient technique for analysis of molecular markers. Prospectively collected samples have been reported to give excellent concordance between TMA data and corresponding whole-sections. The aim was to evaluate the usefulness of TMA in a population-based cohort of 213 women with ducta...

journal_title：Histopathology

authors： Wärnberg F,Amini RM,Goldman M,Jirström K

更新日期：2008-12-01 00:00:00

abstract：:A clinicopathologic study of histiocytosis X in lymph nodes disclosed a special variant: primary eosinophilic granuloma of lymph nodes. This variant involves one or more lymph nodes, but does not infiltrate any other organs. Histologically, the infiltration of lymph nodes by histiocytosis X cells and eosinophils is si...

journal_title：Histopathology

authors： Motoi M,Helbron D,Kaiserling E,Lennert K

更新日期：1980-11-01 00:00:00

abstract：:Urothelial carcinoma of the urinary bladder is a heterogeneous disease with multiple possible treatment modalities and a wide spectrum of clinical outcome. Treatment decisions and prognostic expectations hinge on accurate and precise staging, and the recently published American Joint Committee on Cancer (AJCC) Staging...

journal_title：Histopathology

authors： Magers MJ,Lopez-Beltran A,Montironi R,Williamson SR,Kaimakliotis HZ,Cheng L

更新日期：2019-01-01 00:00:00

abstract：:An immunohistochemical study of non-small cell lung carcinoma using PC10, a monoclonal antibody against PCNA, was performed on tissues routinely processed with formalin fixation and paraffin embedding. The PCNA labelling index and mitotic index were determined from sections of these tissues. Tumours showed a high mean...

journal_title：Histopathology

authors： Theunissen PH,Leers MP,Bollen EC

更新日期：1992-03-01 00:00:00

abstract：AIM:To train and individually validate a group of breast pathologists in specialty-specific digital primary diagnosis by using a novel protocol endorsed by the Royal College of Pathologists' new guideline for digital pathology. The protocol allows early exposure to live digital reporting, in a risk-mitigated environmen...

journal_title：Histopathology

authors： Williams BJ,Hanby A,Millican-Slater R,Nijhawan A,Verghese E,Treanor D

更新日期：2018-03-01 00:00:00

abstract：AIMS:Breast cancer 1 (BRCA1) expression is down-regulated in a significant proportion of non-hereditary breast cancers, in the absence of any mutation. This phenomenon is more pronounced in oestrogen (ER)-negative tumours. Recent studies have suggested that inhibitor of DNA binding 4 (ID4), as well as p53, participate ...

journal_title：Histopathology

authors： Thike AA,Tan PH,Ikeda M,Iqbal J

更新日期：2016-04-01 00:00:00