Diagnostic utility of BAP1 and EZH2 expression in malignant mesothelioma.

abstract：AIMS:Tumour necrosis factor (TNF)-alpha induces death or cell proliferation by activation of nuclear factor (NF)-kappaB, also activated by interleukin (IL)-1 alpha. The aim was to investigate upstream and downstream components of NIK transduction pathway in normal (NP), benign prostatic hyperplasia (BPH), prostatic int...

journal_title：Histopathology

authors： Nuñez C,Cansino JR,Bethencourt F,Pérez-Utrilla M,Fraile B,Martínez-Onsurbe P,Olmedilla G,Paniagua R,Royuela M

更新日期：2008-08-01 00:00:00

abstract：AIMS:  Poorly differentiated thyroid carcinomas (PDTC) are an ongoing diagnostic challenge. Although the Turin consensus criteria for PDTC excluded consideration of oncocytic tumours, the World Health Organization (WHO) classification does recognise an oncocytic variant of conventional PDTC. The aims of this study were...

journal_title：Histopathology

authors： Dettmer M,Schmitt A,Steinert H,Moch H,Komminoth P,Perren A

更新日期：2012-06-01 00:00:00

abstract：AIMS:Mucinous tubular and spindle cell carcinoma (MTSC) of the kidney is a distinct entity characterized by bland tightly packed elongated tubules and spindle cells with low nucleolar grade in a basophilic mucinous stroma. Several case studies have reported MTSC with high-grade features and have brought into question w...

journal_title：Histopathology

authors： Sadimin ET,Chen YB,Wang L,Argani P,Epstein JI

更新日期：2017-11-01 00:00:00

abstract：:A series of 115 consecutive, non-ulcerous, dyspeptic patients were examined for Helicobacter pylori (H. pylori) colonization in the gastric antral and/or body mucosa using Giemsa staining. Findings were correlated with the presence and degree of activity of superficial gastritis, deep gastritis, atrophic gastritis and...

journal_title：Histopathology

authors： Rugge M,Di Mario F,Cassaro M,Baffa R,Farinati F,Rubio J Jr,Ninfo V

更新日期：1993-01-01 00:00:00

abstract：AIMS:The clinical outcome of patients with locally advanced rectal cancer who undergo neoadjuvant chemoradiotherapy (CRT) is influenced by the tumour response to treatment, which is reflected by tumour regression grade and post-treatment (y) TNM stage. Little is known about the prognostic value of pretreatment histopat...

journal_title：Histopathology

authors： Reggiani Bonetti L,Lionti S,Domati F,Pagliani G,Mattioli E,Barresi V

更新日期：2017-09-01 00:00:00

abstract：AIMS:Pulmonary chondromas, which are rare cartilaginous neoplasms that often arise in the setting of Carney triad, are morphologically similar to pulmonary hamartomas, which are much more common. There is evidence that succinate dehydrogenase (SDH) deficiency drives neoplasia in patients with Carney triad, and SDHB imm...

journal_title：Histopathology

authors： Chatzopoulos K,Fritchie KJ,Aubry MC,Carney JA,Folpe AL,Boland JM

更新日期：2019-12-01 00:00:00

abstract：AIMS:To undertake a clinicopathological study of diffuse serosal neoplasms of epithelial histogenesis which clinically and pathologically mimic malignant pleural mesothelioma. METHODS AND RESULTS:Over a 10-year (1990-2000) study period 53 carcinomas mimicking diffuse pleural mesothelioma ('pseudomesotheliomatous' carc...

journal_title：Histopathology

authors： Attanoos RL,Gibbs AR

更新日期：2003-11-01 00:00:00

abstract：:A Sertoli-Leydig cell tumour of testis presented some diagnostic difficulties. The tumour cells showed strong expression of S-100 antigen. Preliminary study of non-neoplastic testis suggests that Leydig cells and, to a lesser extent, Sertoli cells express S-100 antigen; its localization may be of value in the diagnosi...

journal_title：Histopathology

authors： McLaren K,Thomson D

更新日期：1989-12-01 00:00:00

abstract：AIMS:Fos-related antigen 1 (Fra-1) is a member of the activator protein 1 (AP-1) transcription factor family. Our objective was to evaluate the role of Fra-1 expression in breast carcinoma progression and prognosis. METHODS AND RESULTS:Fra-1 expression was investigated by immunohistochemistry in two tissue microarrays...

journal_title：Histopathology

authors： Logullo AF,Stiepcich MM,Osório CA,Nonogaki S,Pasini FS,Rocha RM,Soares FA,Brentani MM

更新日期：2011-03-01 00:00:00

abstract：:Morphometric methods were applied to predict the clinical course of individual patients with breast cancer. Measurement of tumour diameter, assessment of mitotic and cellular indices, and quantitative microscopy of nuclear features were assessed together with nuclear features and histological grades. Of the tumours fr...

journal_title：Histopathology

authors： Baak JP,Kurver PH,De Snoo-Niewlaat AJ,De Graef S,Makkink B,Boon ME

更新日期：1982-05-01 00:00:00

abstract：AIMS:To ascertain the prognostic relevance of micropapillary carcinoma, a specific type of breast tumour. METHODS AND RESULTS:We interrogated the clinical records of a series of 49 pure micropapillary carcinoma patients and 13 487 invasive ductal carcinoma patients, diagnosed and treated consecutively in our instituti...

journal_title：Histopathology

authors： Vingiani A,Maisonneuve P,Dell'orto P,Farante G,Rotmensz N,Lissidini G,Del Castillo A,Renne G,Luini A,Colleoni M,Viale G,Pruneri G

更新日期：2013-08-01 00:00:00

abstract：:Human T-cell leukaemia/lymphoma virus type 1 (HTLV-1), a causative virus of adult T-cell leukaemia/lymphoma (ATLL), is known to be transmitted by breast-feeding. Using a monoclonal antibody HML-1 which labels human intestinal intra-epithelial T lymphocytes, we have immunohistochemically examined ATLL tissues in order ...

journal_title：Histopathology

authors： Kitajima S,Tokunaga M,Goto M,Sato E,Utsunomiya A,Ohtsuka M,Hanada S,Arima T

更新日期：1994-09-01 00:00:00

abstract：:A study was made of the cells forming the crescents in human crescentic glomerulonephritis. The investigation was performed using a panel of antibodies with immunoperoxidase techniques in formalin fixed, paraffin embedded renal biopsy material. Some of the cells of glomerular crescents were found to contain cytokerati...

journal_title：Histopathology

authors： Harrison DJ,MacDonald MK

更新日期：1986-09-01 00:00:00

abstract：AIMS:Alterations in the expression of several long non-coding RNAs (lncRNAs) have been found in primary nasopharyngeal carcinoma (NPC). However, the effect of lncRNA expression on primary NPC as well as the molecular mechanism of lncRNA remains vague. This study was to identify differentially expressed lncRNAs involved...

journal_title：Histopathology

authors： Yang QQ,Deng YF

更新日期：2015-06-01 00:00:00

abstract：AIMS:Perineural invasion (PNI) by prostatic adenocarcinoma is debated as a prognostic parameter. This study investigates the prognostic predictive value of PNI in a series of patients with locally advanced prostate cancer treated with radiotherapy and androgen deprivation using 10 years outcome data from the TROG 03.04...

journal_title：Histopathology

authors： Delahunt B,Murray JD,Steigler A,Atkinson C,Christie D,Duchesne G,Egevad L,Joseph D,Matthews J,Oldmeadow C,Samaratunga H,Spry NA,Srigley JR,Hondermarck H,Denham JW

更新日期：2020-08-01 00:00:00

abstract：AIMS:Trichoblastic carcinomas (malignant trichoblastomas) are rare and poorly documented neoplasms characterized by malignant transformation of a pre-existing benign trichoblastoma and subdivided histologically into low- and high-grade tumours. While morphologically low-grade trichoblastic carcinomas show an indolent b...

journal_title：Histopathology

authors： Mehta A,Davey J,Wiedemeyer K,Brenn T

更新日期：2021-01-03 00:00:00

abstract：AIMS:Lung cancer patients within the pN0 category have a significantly different outcome. The aim of this study was to develop a mathematical model to assist in predicting the prognosis of pN0 lung squamous cell carcinoma (SCC). METHODS AND RESULTS:Twenty-three proteins were examined by immunohistochemical (IHC) analy...

journal_title：Histopathology

authors： Liu Y,Lin D,Xiao T,Ma Y,Hu Z,Zheng H,Zheng S,Liu Y,Li M,Li L,Cao Y,Guo S,Han N,Di X,Zhang K,Cheng S,Gao Y

更新日期：2011-11-01 00:00:00

abstract：AIMS:In addition to predominant granulocytic proliferation, bone marrow morphology in Philadelphia chromosome positive (Ph1+) CML is characterized by atypical dwarf or microforms of megakaryocytes. However, following therapy with interferon-alpha 2b (IFN), these micromegakaryocytes occur less frequently. The purpose of...

journal_title：Histopathology

authors： Thiele J,Schmitz B,Gross H,Kvasnicka HM,Niederle N,Leder LD,Fischer R

更新日期：1997-09-01 00:00:00

abstract：AIMS:p53 immunostaining in Barrett's oesophagus (BO) has been shown to be predictive of progression, but data regarding its generalizability to routine practice are lacking. This study compared the reliability of p53 and dysplasia interpretation and grading. METHODS AND RESULTS:Seventy-two cases encompassing the full ...

journal_title：Histopathology

authors： Kaye PV,Ilyas M,Soomro I,Haider SA,Atwal G,Menon S,Gill S,Richards C,Harrison R,West K,Ragunath K

更新日期：2016-09-01 00:00:00

abstract：:In the course of running two clinical trials between 1966 and 1985, data became available for 1315 patients, 713 in the first trial and 602 patients in the second trial, which has allowed comparison between histological findings in laryngeal and hypopharyngeal carcinoma, the observed survival and the tumour-free rates...

journal_title：Histopathology

authors： Wiernik G,Millard PR,Haybittle JL

更新日期：1991-11-01 00:00:00

abstract：:Delta hepatitis (HDV) infection can only occur in the presence of hepatitis B (HBV) infection, as HDV requires a coat of HBV surface antigen (HBsAg) for assembly of complete virus. A number of studies have examined the variation of HBV markers in serum and liver during establishment of HDV infection, but none has syst...

journal_title：Histopathology

authors： Ryley NG,Heryet AR,Goldin R,Monjardino J,Saldanha J,Fleming KA

更新日期：1992-04-01 00:00:00

abstract：:We have reviewed 60 liver specimens from 47 patients with the diagnosis of incomplete septal cirrhosis observed between 1968 and 1987. In reaching this diagnosis evaluation of the following histological features appeared to be helpful: parenchymal nodularity, thin incomplete septa, hypoplastic portal tracts, increased...

journal_title：Histopathology

authors： Sciot R,Staessen D,Van Damme B,Van Steenbergen W,Fevery J,De Groote J,Desmet VJ

更新日期：1988-12-01 00:00:00

abstract：:In reviewing a large series of soft tissue tumours, seven cases of benign plexiform schwannoma have been retrieved. These were solitary lesions, not associated with von Recklinghausen's neurofibromatosis, which arose in the dermis or subcutaneous tissue, predominantly in young adults. None has recurred. While the schw...

journal_title：Histopathology

authors： Fletcher CD,Davies SE

更新日期：1986-09-01 00:00:00

abstract：:Gonadoblastoma is defined as a neoplasm containing nests of germ cells and cells resembling Sertoli cells or granulosa cells. Gonadoblastomas arise almost exclusively in dysgenetic gonads. They are associated with an increased risk of developing germ cell tumours. Testicular germ cell tumours in adults are preceded by...

journal_title：Histopathology

authors： Jørgensen N,Müller J,Jaubert F,Clausen OP,Skakkebaek NE

更新日期：1997-02-01 00:00:00

abstract：AIMS:A systematic review of published reports that have evaluated the ability of immunohistochemistry and argyrophil nucleolar organizing region (AgNOR) staining to distinguish between benign and malignant pleural disease. METHODS:Nineteen relevant papers published during the period 1979-2005 were identified. Individu...

journal_title：Histopathology

authors： King J,Thatcher N,Pickering C,Hasleton P

更新日期：2006-12-01 00:00:00

abstract：:We investigated the expression of androgen receptor (AR) protein in transitional cell carcinoma of human urinary bladder in paraffin-embedded sections of tumours obtained from nine patients with urinary bladder cancer treated by radical cystectomy. In addition, immunoblotting of AR was also performed on selected sampl...

journal_title：Histopathology

authors： Zhuang YH,Bläuer M,Tammela T,Tuohimaa P

更新日期：1997-06-01 00:00:00

abstract：:Upper gastrointestinal endoscopic examination of 40 patients on immunosuppressive therapy after successful kidney transplantation revealed a duodenal ulcer in four cases and duodenal erosions in six. Between four and six biopsies were collected from the antral and the fundal mucosa in each case and from the duodenal m...

journal_title：Histopathology

authors： Franzin G,Musola R,Mencarelli R

更新日期：1982-07-01 00:00:00

abstract：AIMS:Rheumatoid arthritis (RA) and pigmented villonodular synovitis (PVNS) are aggressive diseases with progressive joint destruction. The present study aims to define cell cycle phases, polyploidy and the immunophenotype of proliferating synovial cells in both diseases. METHODS AND RESULTS:Synovial tissues from patie...

journal_title：Histopathology

authors： Berger I,Weckauf H,Helmchen B,Ehemann V,Penzel R,Fink B,Bernd L,Autschbach F

更新日期：2005-05-01 00:00:00

abstract：AIMS:Comedo carcinoma is generally regarded as the subtype of ductal carcinoma in situ (DCIS) most likely to progress to invasive carcinoma. Increased angiogenesis could be associated with an enhanced risk of progression and might therefore be a marker of poor prognosis, as can be demonstrated for invasive breast tumou...

journal_title：Histopathology

authors： Vogl G,Dietze O,Hauser-Kronberger C

更新日期：2005-12-01 00:00:00

abstract：AIMS:To investigate expression of nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) as a diagnostic tool to improve grading of dysplasia in Barrett's oesophagus patients. METHODS AND RESULTS:Immunostaining was analysed on a total of 192 biopsy samples of 22 Barrett's patients with no dysplasia...

journal_title：Histopathology

authors： van de Winkel A,van Zoest KP,van Dekken H,Moons LM,Kuipers EJ,van der Laan LJ

更新日期：2011-01-01 00:00:00