Quality aspects of the tissue microarray technique in a population-based cohort with ductal carcinoma in situ of the breast.

abstract：:Of 44 intraoral salivary gland tumours received by the Department of Pathology, Dental Faculty, University of Oslo over the last 20 years, 21 (approx. 48%) were classified as carcinomas. Of these, the adenocarcinomas constituted the largest group, but because some of them bore a certain likeness to adenoid cystic carc...

journal_title：Histopathology

authors： Stene T,Koppang HS

更新日期：1978-01-01 00:00:00

abstract：AIMS:Atypical polypoid adenomyoma (APAM) is an uncommon uterine lesion composed of complex endometrioid glands with frequent squamous morular metaplasia and fibromuscular stroma. On endometrial curettage, biopsy, or polypectomy specimens, the admixture of endometrioid glands and smooth muscle raises the differential di...

journal_title：Histopathology

authors： Worrell HI,Sciallis AP,Skala SL

更新日期：2021-01-18 00:00:00

abstract：:The expression of cytokeratin intermediate filaments by a tumour has been accepted as evidence of an epithelial origin. Although there have been anecdotal reports of cytokeratin expression within tissues and neoplasms of non-epithelial origin, particularly muscle, there have been no comprehensive studies of its freque...

journal_title：Histopathology

authors： Brown DC,Theaker JM,Banks PM,Gatter KC,Mason DY

更新日期：1987-05-01 00:00:00

abstract：:Chromosomal rearrangements resulting in the fusion of coding parts from two genes or in the exchange of regulatory sequences are present in approximately 20% of all human neoplasms. More than 1000 such gene fusions have now been described, with close to 100 of them in soft tissue tumours. Although little is still know...

journal_title：Histopathology

authors： Mertens F,Tayebwa J

更新日期：2014-01-01 00:00:00

abstract：AIM:Combined hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) (cHCC-CC) is a rare biphasic liver cancer. Recent studies have demonstrated that cHCC-CC originates from hepatic progenitor cells (HPCs). Spalt-like transcription factor 4 (SALL4) is a marker for a progenitor subclass of HCC with an aggressive phen...

journal_title：Histopathology

authors： Tanaka Y,Aishima S,Kohashi K,Okumura Y,Wang H,Hida T,Kotoh K,Shirabe K,Maehara Y,Takayanagi R,Oda Y

更新日期：2016-04-01 00:00:00

abstract：AIMS:High levels of autofluorescence in tissue samples can entirely mask specific labellings with fluorophores and thus impair immunofluorescence histochemistry. In pancreatic tissue samples we observed autofluorescence as a common problem often mediated by the fixation and processing procedure. METHODS AND RESULTS:Us...

journal_title：Histopathology

authors： Erben T,Ossig R,Naim HY,Schnekenburger J

更新日期：2016-09-01 00:00:00

abstract：AIMS:Hypoxia-inducible factor-1 (HIF-1) activity is regulated by prolyl hydroxylase (PHD1, PHD2, PHD3) and factor inhibiting HIF-1 (FIH) that target the α subunit of HIF-1 (HIF-1α) for proteosomal degradation. We hypothesised that the elevated HIF-1α level is due in some tumours to epigenetic silencing by DNA hypermeth...

journal_title：Histopathology

authors： Huang KT,Mikeska T,Dobrovic A,Fox SB

更新日期：2010-09-01 00:00:00

abstract：AIMS:To survey current European practices in handling and reporting of radical prostatectomy (RP) specimens. METHODS AND RESULTS:A European Network of Uropathology (ENUP) was organized for the dissemination of information, survey studies and research collaborations. Contact data of uropathologists were collected from ...

journal_title：Histopathology

authors： Egevad L,Algaba F,Berney DM,Boccon-Gibod L,Griffiths DF,Lopez-Beltran A,Mikuz G,Varma M,Montironi R,European Network of Uropathology.

更新日期：2008-09-01 00:00:00

abstract：AIMS:Tumour budding is an adverse prognostic factor in colorectal cancer (CRC). We have investigated the significance of cytoplasmic fragments occurring in the immediate vicinity of tumour budding foci. METHODS AND RESULTS:Seventy-three CRCs with high-grade budding (> 10 budding foci in a x 20 objective field) were cl...

journal_title：Histopathology

authors： Shinto E,Mochizuki H,Ueno H,Matsubara O,Jass JR

更新日期：2005-07-01 00:00:00

abstract：:Two series of cutaneous malignant melanoma (CMM), one from a low incidence area (the Oxford Region) and one from a high incidence area (Western Australia), were compared by one pathologist using the same histological criteria. The findings included similarities in the distributions of histogenetic type of CMM, predomi...

journal_title：Histopathology

authors： Heenan PJ,Holman CD

更新日期：1982-11-01 00:00:00

abstract：AIM:To assess a new HER2 fluorescence in situ hybridization (FISH) test and report on multicentre intrasite and intersite variation. METHODS AND RESULTS:HER2 results were scored from 45 breast cancers in eight laboratories using the Kreatech Poseidon HER2 FISH probe (Kreatech Diagnostics, Amsterdam, the Netherlands). ...

journal_title：Histopathology

authors： Bartlett JM,Campbell FM,Ibrahim M,Thomas J,Wencyk P,Ellis I,Kay E,Connolly Y,O'Grady A,Barnett S,Starczynski J,Cunningham P,Miller K

更新日期：2010-02-01 00:00:00

abstract：AIMS:Regional differences in proliferative activity are commonly seen within breast cancers, but little is known on the extent of intratumoral heterogeneity of Ki67 expression. Our aim was to study the intratumoral heterogeneity of Ki67 expression in early breast cancers and its association with clinicopathological fea...

journal_title：Histopathology

authors： Focke CM,Decker T,van Diest PJ

更新日期：2016-11-01 00:00:00

abstract：AIMS:Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland carcinomas. Epidermal growth factor receptor (EGFR) signalling pathway gene mutations are important in predicting a patient's prognosis, selecting molecularly targeted drugs and estimating the efficacy of a molecular therapy. However, their si...

journal_title：Histopathology

authors： Morita M,Murase T,Okumura Y,Ueda K,Sakamoto Y,Masaki A,Kawakita D,Tada Y,Nibu KI,Shibuya Y,Inagaki H

更新日期：2020-06-01 00:00:00

abstract：AIMS:AP2alpha (TFAP2A) and AP2gamma (TFAP2G) transcription factors have been implicated in the control of proliferation, differentiation and apoptosis of normal breast epithelium and in breast cancer. The aim of this study was to provide a comprehensive analysis of the expression patterns of TFAP2A and TFAP2G in the de...

journal_title：Histopathology

authors： Friedrichs N,Steiner S,Buettner R,Knoepfle G

更新日期：2007-12-01 00:00:00

abstract：:Elastosis, a previously unreported feature, was found to be common in granular cell tumours. Twenty-four of 28 consecutive granular cell tumours were shown to display elastosis. The elastosis was found in three main sites: adventitial, interstitial and septal. Elastosis is statistically associated with the fibrosis pr...

journal_title：Histopathology

authors： McMahon JN,Rigby HS,Davies JD

更新日期：1990-01-01 00:00:00

abstract：:A series of 256 bone marrow biopsy specimens was obtained at different times from a group of patients with acute myeloid leukaemia, chronic granulocytic leukaemia and acute lymphoblastic leukaemia, and was analysed in parallel with peripheral blood smears and bone marrow aspirate samples. In five of these biopsy speci...

journal_title：Histopathology

authors： Islam A,Henderson ES

更新日期：1988-06-01 00:00:00

abstract：AIMS:Multidrug resistance (MDR) is a major obstacle in the treatment of lymphoma. The expression of MDR-1 mRNA and P-glycoprotein (MDR-1/P-gp) has been linked to MDR. We aimed to investigate the expression of MDR-1/P-gp in B-cell lymphoma. METHODS AND RESULTS:Samples at diagnosis and relapse from 10 patients with B-ce...

journal_title：Histopathology

authors： Liu Q,Ohshima K,Kikuchi M

更新日期：2001-03-01 00:00:00

abstract：AIMS:To investigate the clinicopathological and molecular features of primary effusion lymphoma (PEL) in Taiwan and the association with human immunodeficiency virus (HIV), human herpesvirus 8 (HHV8) and Epstein-Barr virus (EBV). METHODS AND RESULTS:We investigated retrospectively 26 cases with a median age of 76.5. O...

journal_title：Histopathology

authors： Chen BJ,Wang RC,Ho CH,Yuan CT,Huang WT,Yang SF,Hsieh PP,Yung YC,Lin SY,Hsu CF,Su YZ,Kuo CC,Chuang SS

更新日期：2018-05-01 00:00:00

abstract：AIMS:In addition to predominant granulocytic proliferation, bone marrow morphology in Philadelphia chromosome positive (Ph1+) CML is characterized by atypical dwarf or microforms of megakaryocytes. However, following therapy with interferon-alpha 2b (IFN), these micromegakaryocytes occur less frequently. The purpose of...

journal_title：Histopathology

authors： Thiele J,Schmitz B,Gross H,Kvasnicka HM,Niederle N,Leder LD,Fischer R

更新日期：1997-09-01 00:00:00

abstract：AIMS: Three histological variants of dysembryoplastic neuroepithelial tumour (DNT) have been described, namely, simple, complex and non-specific. However, the concept of non-specific variants of DNT remains controversial, because they cannot be accurately distinguished by histological findings alone from ordinary gliom...

journal_title：Histopathology

authors： Sung CO,Suh YL,Hong SC

更新日期：2011-08-01 00:00:00

abstract：AIMS:There is increasing evidence of Gleason score (GS) drift in prostatic core biopsies during the last two decades. The ProtecT study is a randomized controlled study and provides an excellent cohort to study the effect of time, prostate-specific antigen (PSA) level, perineural invasion, tumour length and age on GS. ...

journal_title：Histopathology

authors： Oxley J,Simpkin A,Goepel J,Varma M,Griffiths D,Grigor K,Mayer N,Warren A,Deshmukh N,Bhattarai S,Dormer J,Hounsome L,Adamczyk LA,Metcalfe C,Lane JA,Davis M,Donovan JL,Neal DE,Hamdy FC,Robinson MC,ProtecT Study Grou

更新日期：2015-02-01 00:00:00

abstract：:A series of 20 cases of radiation bowel disease (RBD) was studied qualitatively and the arterial changes were studied quantitatively. A control series of 45 cases was studied. In the control cases there were positive correlations between the medial thickness of all vessels studied and the diastolic blood pressure as w...

journal_title：Histopathology

authors： Hasleton PS,Carr N,Schofield PF

更新日期：1985-05-01 00:00:00

abstract：:Granular cell tumours rarely involve the lower respiratory tract. We report eight cases surgically resected at our institution. There were four females and four males, aged between 18 to 56 years (mean 40). One tumour associated with a peripheral lung adenocarcinoma was asymptomatic. The other lesions presented with o...

journal_title：Histopathology

authors： Thomas de Montpréville V,Dulmet EM

更新日期：1995-09-01 00:00:00

abstract：:Eight cases of myelosarcoma without acute leukaemia at time of diagnosis were reviewed and biopsies were immunostained using antibodies reacting with myeloid/monocytic markers. Initial tumour location included lymph nodes, paranasal sinuses, nasopharyngeal and/or orbital regions and other extranodal locations. Three c...

journal_title：Histopathology

authors： Furebring-Fredén M,Martinsson U,Sundström C

更新日期：1990-03-01 00:00:00

abstract：AIM:Alveolar capillary dysplasia (ACD) is a rare disorder, typically presenting with persistent pulmonary hypertension of the newborn. The aim was to characterise further the histological features of patients suspected of having ACD and to correlate histopathological features with outcome. METHODS AND RESULTS:Three pa...

journal_title：Histopathology

authors： Melly L,Sebire NJ,Malone M,Nicholson AG

更新日期：2008-10-01 00:00:00

abstract：:A survey of 69 children presenting with recurrent or persistent haematuria and submitted to percutaneous renal biopsy at this hospital over a 17-year period, was performed to establish the incidence of thin basement membrane nephropathy (TBMN). A diagnosis of primary glomerular disease was established in 44 (IgA nephr...

journal_title：Histopathology

authors： Lang S,Stevenson B,Risdon RA

更新日期：1990-04-01 00:00:00

abstract：AIMS:Maspin, a protein belonging to the serpin superfamily, is the product of a tumour suppressor gene. Tissue distribution studies have shown maspin expression in normal mammary epithelial cells, in the placenta, prostate, thymus, testis, oral cavity, small intestine, skin, and cornea. Maspin is expressed but down-reg...

journal_title：Histopathology

authors： Marioni G,Blandamura S,Giacomelli L,Calgaro N,Segato P,Leo G,Fischetto D,Staffieri A,de Filippis C

更新日期：2005-05-01 00:00:00

abstract：AIMS:Lung cancer patients within the pN0 category have a significantly different outcome. The aim of this study was to develop a mathematical model to assist in predicting the prognosis of pN0 lung squamous cell carcinoma (SCC). METHODS AND RESULTS:Twenty-three proteins were examined by immunohistochemical (IHC) analy...

journal_title：Histopathology

authors： Liu Y,Lin D,Xiao T,Ma Y,Hu Z,Zheng H,Zheng S,Liu Y,Li M,Li L,Cao Y,Guo S,Han N,Di X,Zhang K,Cheng S,Gao Y

更新日期：2011-11-01 00:00:00

abstract：:Nineteen out of 121 consecutive cardiac biopsies from 107 patients were found to contain amyloid deposits on routine Congo red screening. Seventeen were left atrial appendages removed during mitral valvotomy for chronic rheumatic mitral valve disease while the remaining two were right atrial appendages excised during ...

journal_title：Histopathology

authors： Looi LM

更新日期：1981-11-01 00:00:00

abstract：:A review of 76 endomyocardial biopsies and 54 autopsies of patients with dilated cardiomyopathy (DCM) revealed features of hypertrophy and degenerative changes associated with long-standing hypertrophy. Long-term survivors had significantly heavier heart weights. Short-term survivors had heavier than normal right vent...

journal_title：Histopathology

authors： Rose AG,Beck W

更新日期：1985-04-01 00:00:00