Prognostication of invasive ductal breast cancer by quantification of E-cadherin immunostaining: the methodology and clinical relevance.

abstract：:A villous adenoma of the duodenum was studied histologically and histochemically by semi-thin sections using glycol-methacrylate as embedding medium. All the four epithelial cell types which are present in normal duodenal mucosa (absorptive columnar, goblet, Paneth, endocrine) were found in the tumour, as well as undi...

journal_title：Histopathology

authors： Mingazzini PL,Malchiodi Albedi F,Blandamura V

更新日期：1982-03-01 00:00:00

abstract：AIMS:Calcific aortic stenosis is a progressive disease characterized by massive fibrosis andmineralization of the valve leaflets. The aim of this study was to determine whether the onset of native calcific aortic stenosis is associated primarily with matrix remodelling events, and particularly with elastin degradation....

journal_title：Histopathology

authors： Perrotta I,Russo E,Camastra C,Filice G,Di Mizio G,Colosimo F,Ricci P,Tripepi S,Amorosi A,Triumbari F,Donato G

更新日期：2011-09-01 00:00:00

abstract：AIMS:To examine the expression of the Bcl-2 family of proteins (Bcl-2, Bcl-x, Bcl-xL and Bax) in classical Hodgkin's lymphoma (cHL) and to correlate the expression of these proteins with proliferation, apoptosis and the presence of Epstein-Barr virus (EBV). METHODS AND RESULTS:Expression of the Bcl-2 family of protein...

journal_title：Histopathology

authors： Kim LH,Nadarajah VS,Peh SC,Poppema S

更新日期：2004-03-01 00:00:00

abstract：AIMS:Ectomesenchymal chondromyxoid tumour (ECT) is a rare, benign intraoral neoplasm showing a predilection for the anterior dorsum of the tongue. The World Health Organization includes ECT in the pathological spectrum of soft tissue myoepithelioma. EWS RNA-binding protein 1 gene (EWSR1) rearrangement is found in 45% o...

journal_title：Histopathology

authors： Argyris PP,Bilodeau EA,Yancoskie AE,Trochesset D,Pambuccian SE,Wetzel SL,Shah SS,Edelman M,Freedman P,Dolan M,Koutlas IG

更新日期：2016-10-01 00:00:00

abstract：:A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein-Barr virus (EBV)-associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV-DNA in tumour tissue. The findings in this...

journal_title：Histopathology

authors： Huang DP,Ng HK,Ho YH,Chan KM

更新日期：1988-11-01 00:00:00

abstract：:Calcitonin is a hypocalcaemia producing hormone and is secreted by C-cells of the thyroid. The current study was undertaken on a hypothesis that C-cell hyperplasia may develop in the secondary hyperparathyroidism of chronic renal failure in response to sustained hypercalcaemia. With an immunoperoxidase staining method...

journal_title：Histopathology

authors： Tomita T,Millard DM

更新日期：1992-11-01 00:00:00

abstract：:Many classification schemes have been proposed for ductal carcinoma in situ. Architectural heterogeneity is widely recognized. Cytonuclear grade appears to have greater prognostic significance than architectural pattern. This study assesses heterogeneity using a classification based on cytological grade and compares t...

journal_title：Histopathology

authors： Harrison M,Coyne JD,Gorey T,Dervan PA

更新日期：1996-05-01 00:00:00

abstract：AIMS:Congenital haemangiomas (CHs) can be subdivided into different subtypes [rapidly involuting CHs (RICHs), non-involuting CHs (NICHs), and partially involuting CHs (PICHs)]. During the first few days of life, RICHs may be associated with transient but sometimes marked thrombocytopenia. We sought to assess the histol...

journal_title：Histopathology

authors： El Zein S,Boccara O,Soupre V,Vieira AF,Bodemer C,Coulomb A,Wassef M,Fraitag S

更新日期：2020-08-01 00:00:00

abstract：AIMS:Class III beta-tubulin (TUBB3) reduces microtubule stability and confers resistance to microtubule-stabilizing taxanes, including paclitaxel and docetaxel. Pancreatic ductal adenocarcinomas show limited responsiveness to taxanes, but little is known of the underlying mechanisms. The aim of this study was to examin...

journal_title：Histopathology

authors： Lee KM,Cao D,Itami A,Pour PM,Hruban RH,Maitra A,Ouellette MM

更新日期：2007-10-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：AIMS:To survey current European practices in handling and reporting of radical prostatectomy (RP) specimens. METHODS AND RESULTS:A European Network of Uropathology (ENUP) was organized for the dissemination of information, survey studies and research collaborations. Contact data of uropathologists were collected from ...

journal_title：Histopathology

authors： Egevad L,Algaba F,Berney DM,Boccon-Gibod L,Griffiths DF,Lopez-Beltran A,Mikuz G,Varma M,Montironi R,European Network of Uropathology.

更新日期：2008-09-01 00:00:00

abstract：AIMS:Polymorphous low-grade adenocarcinoma (PLGA) is the second most common type of malignant neoplasm in minor salivary glands. Its origin in major salivary glands is considered exceedingly rare. Herein, we present three cases of de novo PLGA arising in major salivary glands. METHODS AND RESULTS:Three cases of PLGA w...

journal_title：Histopathology

authors： Nagao T,Gaffey TA,Kay PA,Minato H,Serizawa H,Lewis JE

更新日期：2004-02-01 00:00:00

abstract：INTRODUCTION:We describe cytologic and immunohistologic findings in virus transport medium on cases under investigation of SARS-CoV-2 infection. METHODS:Cytologic findings in cases under investigation of SARS-CoV-2 infection from one hundred consecutive nasopharyngeal swab were reviewed. Immunohistochemistry and SARSC...

journal_title：Histopathology

authors： Parada D,Peña KB,Gumà J,Guilarte C,Riu F

更新日期：2020-09-24 00:00:00

abstract：AIMS:Nitric oxide (NO), produced by inducible NO synthase (iNOS), has been suggested to cause oxidative stress, leading to 8-hydroxydeoxyguanosine (8-OHdG) accumulation and subsequent transversion mutation of DNA. The aim was to evaluate iNOS expression and the status of oxidative stress in nasopharyngeal carcinoma (NP...

journal_title：Histopathology

authors： Segawa Y,Oda Y,Yamamoto H,Uryu H,Shiratsuchi H,Hirakawa N,Tomita K,Yamamoto T,Oda S,Yamada T,Komune S,Tsuneyoshi M

更新日期：2008-01-01 00:00:00

abstract：:Lobular carcinoma in situ and atypical lobular hyperplasia were first described over 50 years ago. Despite this long incubation period, the biological nature of the lesions remains controversial. They are generally regarded as 'risk indicators' of invasive cancer rather than true precursor lesions. When first describe...

journal_title：Histopathology

authors： Lishman SC,Lakhani SR

更新日期：1999-09-01 00:00:00

abstract：AIMS:To investigate whether an antibody against an intracellular epitope can detect CD19 in routine biopsy specimens and thus to document in detail its expression in human lymphomas. METHOD AND RESULTS:A polyclonal antibody to the C terminus of CD19 was used to immunostain paraffin-embedded samples of normal and neopl...

journal_title：Histopathology

authors： Masir N,Marafioti T,Jones M,Natkunam Y,Rüdiger T,Hansmann ML,Mason DY

更新日期：2006-02-01 00:00:00

abstract：AIMS:To test the effectiveness of a teaching resource (a decision tree with diagnostic criteria based on published literature) in improving the proficiency of Gleason grading of prostatic cancer by general pathologists. METHODS:A decision tree with diagnostic criteria was developed by a panel of urological pathologist...

journal_title：Histopathology

authors： Griffiths DF,Melia J,McWilliam LJ,Ball RY,Grigor K,Harnden P,Jarmulowicz M,Montironi R,Moseley R,Waller M,Moss S,Parkinson MC

更新日期：2006-05-01 00:00:00

abstract：:Pancreatic acinar metaplasia of the gastric mucosa is a newly recognized entity. Its physiological relevance and association with other pathological conditions in the stomach remain to be elucidated. We studied by immunohistochemistry the expression of growth markers in the gastric mucosa in biopsies from 15 patients ...

journal_title：Histopathology

authors： Stachura J,Konturek J,Urbańczyk K,Bogdal J,Domschke W

更新日期：1995-12-01 00:00:00

abstract：AIMS:To investigate the prognostic significance of chromosomal alterations in colorectal cancer patients. Histopathological tumour classification is still considered to be the gold standard for the characterization of solid tumours. However, it is well known that such established parameters do not satisfactorily predic...

journal_title：Histopathology

authors： Knösel T,Schlüns K,Stein U,Schwabe H,Schlag PM,Dietel M,Petersen I

更新日期：2003-10-01 00:00:00

abstract：:Ten cases of malignant lymphoma of the colon and rectum complicating chronic inflammatory bowel disease are presented. Seven patients had chronic ulcerative colitis with a history varying from 6 to 20 years. There was extensive colitis in six of these patients and left-sided colitis in one. All seven lymphomas showed ...

journal_title：Histopathology

authors： Shepherd NA,Hall PA,Williams GT,Codling BW,Jones EL,Levison DA,Morson BC

更新日期：1989-10-01 00:00:00

abstract：AIMS:p16, a tumour suppressor gene located at 9p21 chromosome and involved in cell cycle regulation, is often inactivated in lung carcinoma. Inactivation is also supported by the loss of p16 protein, a strong inhibitor of cyclin-dependent kinase (CDK) 4 and 6. The aim of this study was to examine alterations of p16 bot...

journal_title：Histopathology

authors： Dessy E,Rossi E,Berenzi A,Tironi A,Benetti A,Grigolato P

更新日期：2008-03-01 00:00:00

abstract：:The syndrome of postmastectomy lymphangiosarcoma (LAS) has been universally accepted since it was first outlined by Stewart & Treves (1948), except for a small number of authors who concluded that the neoplasms arising in the chronic lymphoedematous arms were in fact due to retrograde spread from the original breast c...

journal_title：Histopathology

authors： Schafler K,McKenzie CG,Salm R

更新日期：1979-03-01 00:00:00

abstract：AIMS:Residual cancer morphology in radical prostatectomies (RPs) after neoadjuvant hormone therapy includes inconspicuous cytology, and treated tumour cells can be difficult to identify in lymph nodes. The aim of this study was to evaluate the role of immunohistochemistry (IHC) in identifying occult lymph node metastas...

journal_title：Histopathology

authors： Kehr E,Masry P,Lis R,Loda M,Taplin ME,Hirsch MS

更新日期：2016-01-01 00:00:00

abstract：AIM:To determine the extent of clonal outgrowth in the lymphocytic tissue infiltrate of lichen sclerosus (LS). The presence of T cells with a monoclonally rearranged T-cell receptor gamma-gene (TCRgamma) has been described in up to 50% of biopsies of vulvar and penile LS. MATERIAL AND RESULTS:We analysed 33 foreskin s...

journal_title：Histopathology

authors： Regauer S,Beham-Schmid C

更新日期：2006-05-01 00:00:00

abstract：AIMS:We investigated a group of oral mucosal lesions with characteristic hyperorthokeratotic foci, which we termed orthokeratotic dysplasia (OKD), to determine if it could be identified as a distinct histopathological entity. METHODS AND RESULTS:We screened 282 surgical specimens from 200 patients with oral leucoplaki...

journal_title：Histopathology

authors： Kobayashi T,Maruyama S,Abé T,Cheng J,Takagi R,Saito C,Saku T

更新日期：2012-11-01 00:00:00

abstract：AIMS:Comedo carcinoma is generally regarded as the subtype of ductal carcinoma in situ (DCIS) most likely to progress to invasive carcinoma. Increased angiogenesis could be associated with an enhanced risk of progression and might therefore be a marker of poor prognosis, as can be demonstrated for invasive breast tumou...

journal_title：Histopathology

authors： Vogl G,Dietze O,Hauser-Kronberger C

更新日期：2005-12-01 00:00:00

abstract：AIMS:Pulmonary adenosquamous carcinoma (ASC) is more aggressive than adenocarcinoma (AC) and squamous cell carcinoma (SCC). The genetic features and biomarkers of ASC are not well known. Here, we attempted to identify potential therapeutic markers for ASC. METHODS AND RESULTS:Surgically resected ASC samples from 65 pa...

journal_title：Histopathology

authors： Watanabe Y,Shiraishi K,Takahashi F,Yoshida A,Suzuki K,Asamura H,Takeuchi M,Furuta K,Tsuta K

更新日期：2015-06-01 00:00:00

abstract：AIMS:Malignant odontogenic tumours (MOTs) are rare neoplasms occurring primarily within the jaw. The objective of this study was to determine the incidence, demographics and clinicopathological features of the MOTs from two institutions. METHODS AND RESULTS:The records of the Department of Oral Pathology, Faculty of D...

journal_title：Histopathology

authors： Chaisuparat R,Sawangarun W,Scheper MA

更新日期：2012-07-01 00:00:00

abstract：:The new World Health Organization (WHO) classification of soft tissue tumours was published in early 2013, almost 11 years after the previous edition. While the number of newly recognized entities included for the first time is fewer than that in 2002, there have instead been substantial steps forward in molecular gen...

journal_title：Histopathology

authors： Fletcher CD

更新日期：2014-01-01 00:00:00

abstract：AIMS:Malignant pleural mesothelioma (MPM) is a rare malignancy with a dismal prognosis. While the epithelioid type is associated with a more favourable outcome, additional factors are needed to further stratify prognosis and to identify patients who can benefit from multimodal treatment. As epithelioid MPM shows remark...

journal_title：Histopathology

authors： Bilecz A,Stockhammer P,Theegarten D,Kern I,Jakopovic M,Samarzija M,Klikovits T,Hoda MA,Döme B,Oberndorfer F,Muellauer L,Fillinger J,Kovács I,Pirker C,Schuler M,Plönes T,Aigner C,Klepetko W,Berger W,Brcic L,Laszlo

更新日期：2020-07-01 00:00:00