Detecting metastatic prostate carcinoma in pelvic lymph nodes following neoadjuvant hormone therapy: the eyes have it!

abstract：:Hyaline eosinophilic globules have so far been described in a restricted variety of tumour types. We have noted their presence in a variety of gynaecological malignancies, in particular mixed Müllerian tumours and other epithelial ovarian tumours. We therefore studied their incidence and distribution in a series of ma...

journal_title：Histopathology

authors： al-Nafussi AI,Hughes DE,Williams AR

更新日期：1993-12-01 00:00:00

abstract：AIMS:Polymorphous low-grade adenocarcinoma (PLGA) is the second most common type of malignant neoplasm in minor salivary glands. Its origin in major salivary glands is considered exceedingly rare. Herein, we present three cases of de novo PLGA arising in major salivary glands. METHODS AND RESULTS:Three cases of PLGA w...

journal_title：Histopathology

authors： Nagao T,Gaffey TA,Kay PA,Minato H,Serizawa H,Lewis JE

更新日期：2004-02-01 00:00:00

abstract：:Signet ring cell differentiation in adenocarcinoma of the prostate is uncommon. In a review of 200 cases of prostatic carcinoma, we identified five cases with this change, all in moderately to poorly differentiated prostatic carcinomas. The signet ring cells in prostatic carcinoma contain an intracytoplasmic lumen, sh...

journal_title：Histopathology

authors： Guerin D,Hasan N,Keen CE

更新日期：1993-04-01 00:00:00

abstract：AIMS:The morphological criteria for identification of intercalated duct lesions (IDLs) of salivary glands have been defined recently. It has been hypothesised that IDL could be a precursor of basal cell adenoma (BCA). BCAs show a variety of histological patterns, and the tubular variant is the one that presents the str...

journal_title：Histopathology

authors： Montalli VA,Martinez E,Tincani A,Martins A,Abreu Mdo C,Neves C,Costa AF,Araújo VC,Altemani A

更新日期：2014-05-01 00:00:00

abstract：AIMS:Gallbladder cancer (GBC) is an aggressive tumour that is usually diagnosed at advanced stages and is characterised by a poor prognosis. Using public data of normal human tissues, we found that mRNA and protein levels of mucin 5B (MUC5B) and carbonic anhydrase 9 (CA9) were highly increased in gallbladder tissues. I...

journal_title：Histopathology

authors： Espinoza JA,Riquelme I,Sagredo EA,Rosa L,García P,Bizama C,Apud-Bell M,Leal P,Weber H,Benavente F,Vargas S,Romero D,Kalergis AM,Roa JC

更新日期：2019-03-01 00:00:00

abstract：AIMS:p53 immunostaining in Barrett's oesophagus (BO) has been shown to be predictive of progression, but data regarding its generalizability to routine practice are lacking. This study compared the reliability of p53 and dysplasia interpretation and grading. METHODS AND RESULTS:Seventy-two cases encompassing the full ...

journal_title：Histopathology

authors： Kaye PV,Ilyas M,Soomro I,Haider SA,Atwal G,Menon S,Gill S,Richards C,Harrison R,West K,Ragunath K

更新日期：2016-09-01 00:00:00

abstract：:Waldeyer ring lymphomas belong to a category of tumours which has not yet been fully defined. Their relation to mucosa-associated lymphoid tissue (MALT) and other extranodal lymphomas remains largely unknown. We performed a clinicopathological retrospective study of 79 patients, and compared them with a series of MALT...

journal_title：Histopathology

authors： Menárguez J,Mollejo M,Carrión R,Oliva H,Bellas C,Forteza J,Martin C,Ruiz-Marcellán C,Morente M,Romagosa V

更新日期：1994-01-01 00:00:00

abstract：AIMS:Chondrosarcoma is primarily a tumour of adulthood and old age. Some studies indicate that survival is worse in paediatric than in adult chondrosarcomas. In view of the rarity of paediatric chondrosarcoma, few large studies are currently available. METHODS AND RESULTS:We evaluated the clinical, radiological and pa...

journal_title：Histopathology

authors： Gambarotti M,Righi A,Picci P,Bertoni F,Manfrini M,Donati DM,Dei Tos AP,Vanel D

更新日期：2016-06-01 00:00:00

abstract：:Extramural venous invasion (EMVI) is a well-known prognostic factor in colorectal cancer (CRC). Vascular invasion within the bowel wall, intramural vascular invasion (IMVI), has received less attention and its incidence and prognostic importance in CRC is not completely known. A systematic literature search was perfor...

journal_title：Histopathology

authors： Knijn N,van Exsel UEM,de Noo ME,Nagtegaal ID

更新日期：2018-04-01 00:00:00

abstract：AIMS:SOX11 is known as an essential transcription factor for regulating neurogenesis. Recently, SOX11 has been suggested to be a diagnostic marker and oncogene because of its significant expression in mantle cell lymphoma (MCL). However, SOX11 expression in other tumour types has not yet been extensively studied. METH...

journal_title：Histopathology

authors： Xu S,Dong Y,Huo Z,Yu L,Xue J,Wang G,Duan Y

更新日期：2019-02-01 00:00:00

abstract：:A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein-Barr virus (EBV)-associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV-DNA in tumour tissue. The findings in this...

journal_title：Histopathology

authors： Huang DP,Ng HK,Ho YH,Chan KM

更新日期：1988-11-01 00:00:00

abstract：:Valve replacement started in 1960, with the surgeon now having a significant variety of prosthetic heart valves from which to choose. These valves are broadly divided into mechanical heart valves (MHV) and bioprosthetic heart valves (BHV). Improvements in the performance and ease of usage of BHV without the need for a...

journal_title：Histopathology

authors： Siddiqui RF,Abraham JR,Butany J

更新日期：2009-08-01 00:00:00

abstract：:Clinicopathological and immunohistological features of three cases of large cell lymphoma of bone are reported. On histological grounds, all the cases were diagnosed as histiocytic lymphomas (Rappaport) or primary centroblastic lymphomas, polymorphic subtype (Kiel). On immunophenotyping, malignant cells strongly react...

journal_title：Histopathology

authors： Falini B,Binazzi R,Pileri S,Mori A,Bertoni F,Canino S,Fagioli M,Minelli O,Ciani C,Pellicioli P

更新日期：1988-02-01 00:00:00

abstract：AIMS:To investigate the expression and the prognostic role of glycoprotein Tenascin-C (Tn-C) in primary melanoma of the skin. METHODS AND RESULTS:The immunohistochemical expression of Tn-C was studied in 98 primary melanomas and related to inflammation, invasion, and patient outcome. Patients were followed up for dise...

journal_title：Histopathology

authors： Ilmonen S,Jahkola T,Turunen JP,Muhonen T,Asko-Seljavaara S

更新日期：2004-10-01 00:00:00

abstract：AIMS:Most primary gastrointestinal lymphomas are of B-cell origin and T-cell origin is very rare. Recent studies have suggested that human T-cell lymphotrophic virus type 1 (HTLV-1) may be involved in the development of primary gastric T-cell lymphoma. We analysed 31 patients with primary gastric T-cell lymphoma in sou...

journal_title：Histopathology

authors： Hatano B,Ohshima K,Katoh A,Kanda M,Kawasaki C,Tsuchiya T,Shimazaki K,Haraoka S,Sugihara M,Suzumiya J,Kikuchi M

更新日期：2002-11-01 00:00:00

abstract：AIMS:Central neurocytoma is a rare central nervous system tumour typically found in the lateral ventricles and at the septum pellucidum. Histologically, it resembles oligodendrogliomas and yet ultrastructurally, it shows neuronal differentiation. Its molecular oncogenesis is not known. The aim of this study was to exam...

journal_title：Histopathology

authors： Tong CY,Ng HK,Pang JC,Hu J,Hui AB,Poon WS

更新日期：2000-08-01 00:00:00

abstract：:Eleven colloid cysts of the third ventricle were investigated by immunohistochemistry using 16 mono- and polyclonal antibodies. Colloid cyst epithelium, choroid plexus epithelium and ependyma showed different immunohistochemical profiles. In particular, antibodies to different cytokeratins and to transthyretin reveale...

journal_title：Histopathology

authors： Kuchelmeister K,Bergmann M

更新日期：1992-07-01 00:00:00

abstract：AIMS:To evaluate concordance, upgrades and downgrades from biopsy to prostatectomy, and associated clincopathological parameters, using the recently proposed Gleason grade groups/International Society of Urologic Pathology (ISUP) grades. METHODS AND RESULTS:We evaluated 2529 patients who underwent biopsy and prostatec...

journal_title：Histopathology

authors： Athanazio D,Gotto G,Shea-Budgell M,Yilmaz A,Trpkov K

更新日期：2017-06-01 00:00:00

abstract：AIMS:Because of the clinical difficulty in identifying the early stages of human immunodeficiency virus (HIV) infection, the histopathologist often has to consider the diagnosis of HIV in tissue samples from patients with no previous suspicion of HIV infection. The aim was to investigate the practicality and utility of...

journal_title：Histopathology

authors： Moonim MT,Alarcon L,Freeman J,Mahadeva U,van der Walt JD,Lucas SB

更新日期：2010-03-01 00:00:00

abstract：AIMS:Three cases with features of so-called 'Warthin-like tumour' of the thyroid (WaLTT) are described, in order to evaluate its relationship with papillary carcinoma (PC). METHODS AND RESULTS:We performed an histological and immunohistochemical study with emphasis on RET/PTC expression. The most striking features are...

journal_title：Histopathology

authors： D'Antonio A,De Chiara A,Santoro M,Chiappetta G,Losito NS

更新日期：2000-06-01 00:00:00

abstract：AIMS:Pulmonary Langerhans cell histiocytosis (PLCH) is an idiopathic cigarette smoking-related disorder of the lung. Molecular changes in cellular or fibrotic stages of PLCH have not been investigated. We studied the prevalence of extracellular signal-regulated kinase (ERK) pathway mutations in different PLCH stages an...

journal_title：Histopathology

authors： Kamionek M,Ahmadi Moghaddam P,Sakhdari A,Kovach AE,Welch M,Meng X,Dresser K,Tomaszewicz K,Cosar EF,Mark EJ,Fraire AE,Hutchinson L

更新日期：2016-09-01 00:00:00

abstract：AIMS:Monocarboxylate transporters (MCTs) have been considered promising targets for cancer therapy, since they facilitate lactate efflux in glycolytic tumours. However, their role in solid tumours is still poorly understood. Thus, the present work aimed to contribute to understanding the involvement of MCT1 and MCT4 in...

journal_title：Histopathology

authors： Pinheiro C,Albergaria A,Paredes J,Sousa B,Dufloth R,Vieira D,Schmitt F,Baltazar F

更新日期：2010-06-01 00:00:00

abstract：AIMS:Maspin, a protein belonging to the serpin superfamily, is the product of a tumour suppressor gene. Tissue distribution studies have shown maspin expression in normal mammary epithelial cells, in the placenta, prostate, thymus, testis, oral cavity, small intestine, skin, and cornea. Maspin is expressed but down-reg...

journal_title：Histopathology

authors： Marioni G,Blandamura S,Giacomelli L,Calgaro N,Segato P,Leo G,Fischetto D,Staffieri A,de Filippis C

更新日期：2005-05-01 00:00:00

abstract：AIMS:In this study, we aimed to investigate the clinicopathological features of CD4+ and/or CD56+ immature haematolymphoid malignancy (iHLM), including blastic plasmacytoid dendritic cell neoplasm (BPDCN). METHODS AND RESULTS:We analysed the clinicopathological features of 46 patients diagnosed consecutively with CD4+...

journal_title：Histopathology

authors： Suzuki Y,Kato S,Kohno K,Satou A,Eladl AE,Asano N,Kono M,Kato Y,Taniwaki M,Akiyama M,Nakamura S

更新日期：2017-12-01 00:00:00

abstract：AIMS:To assess cytokeratin (CK) and thyroid transcription factor (TTF)-1 expression in primary epithelial lung tumours by comparison with non-pulmonary carcinomas and to correlate it with their histological type and grade. METHODS AND RESULTS:Immunohistochemistry using antibodies against CKs 5/6, 7, 19, 20 and TTF-1 w...

journal_title：Histopathology

authors： Jerome Marson V,Mazieres J,Groussard O,Garcia O,Berjaud J,Dahan M,Carles P,Daste G

更新日期：2004-08-01 00:00:00

abstract：AIMS:To assess the outcome of breast papillary lesions diagnosed by ultrasound-guided core needle biopsy (CB) or vacuum-assisted 'mammotome' biopsy (MT), the accuracy of these diagnoses, and whether it is justified not to undertake surgical excision of non-malignant papillary lesions so diagnosed. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Yamaguchi R,Tanaka M,Tse GM,Yamaguchi M,Terasaki H,Hirai Y,Nonaka Y,Morita M,Yokoyama T,Kanomata N,Naito Y,Akiba J,Yano H

更新日期：2015-03-01 00:00:00

abstract：AIMS:Tumour necrosis factor (TNF)-alpha induces death or cell proliferation by activation of nuclear factor (NF)-kappaB, also activated by interleukin (IL)-1 alpha. The aim was to investigate upstream and downstream components of NIK transduction pathway in normal (NP), benign prostatic hyperplasia (BPH), prostatic int...

journal_title：Histopathology

authors： Nuñez C,Cansino JR,Bethencourt F,Pérez-Utrilla M,Fraile B,Martínez-Onsurbe P,Olmedilla G,Paniagua R,Royuela M

更新日期：2008-08-01 00:00:00

abstract：AIMS:There is controversy regarding the use of adjuvant therapy in patients with Dukes' B colorectal cancer (CRC). New markers, identifying high-risk Dukes' B patients, are needed. Here, we examine the utility of Raf kinase inhibitor protein (RKIP) as such a marker and promoter methylation as a mechanism of RKIP down-r...

journal_title：Histopathology

authors： Doyle B,Hagan S,Al-Mulla F,Scott L,Harden S,Paul J,Mulcahy H,Murray GI,Sheahan K,O'Sullivan J,Kolch W

更新日期：2013-02-01 00:00:00

abstract：:Eight cases of myelosarcoma without acute leukaemia at time of diagnosis were reviewed and biopsies were immunostained using antibodies reacting with myeloid/monocytic markers. Initial tumour location included lymph nodes, paranasal sinuses, nasopharyngeal and/or orbital regions and other extranodal locations. Three c...

journal_title：Histopathology

authors： Furebring-Fredén M,Martinsson U,Sundström C

更新日期：1990-03-01 00:00:00

abstract：:Four cases of endocrine neoplasia within fibroadenomas of the breast are described. The tumours are identifiable by light microscopic, silver impregnation and ultrastructural studies. Argyrophilia and the presence of dense-core granules establish the identity of this tumour type. The differential diagnosis from, and p...

journal_title：Histopathology

authors： Eusebi V,Azzopardi JG

更新日期：1980-07-01 00:00:00