Myelosarcoma without acute leukaemia: immunohistochemical and clinico-pathologic characterization of eight cases.

abstract：:A recently developed and validated histochemical method--immunogold-streptavidin enhancement--was used to determine oestrogen receptor content in paraffin sections of breast cancers. The selection of the best cut-off point to define oestrogen receptor status as rich or poor was made on the basis of survival data, usin...

journal_title：Histopathology

authors： Cowen PN,Teasdale J,Jackson P,Reid BJ

更新日期：1990-10-01 00:00:00

abstract：AIMS:Rare gastric lesions composed of a combined proliferation of chief and oxyntic cells have been variably called adenocarcinoma of fundic gland type and oxyntic gland polyp/adenoma. Herein, we present a series of cases that show a morphological spectrum of chief and oxyntic cell proliferations. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Chan K,Brown IS,Kyle T,Lauwers GY,Kumarasinghe MP

更新日期：2016-05-01 00:00:00

abstract：AIM:To train and individually validate a group of breast pathologists in specialty-specific digital primary diagnosis by using a novel protocol endorsed by the Royal College of Pathologists' new guideline for digital pathology. The protocol allows early exposure to live digital reporting, in a risk-mitigated environmen...

journal_title：Histopathology

authors： Williams BJ,Hanby A,Millican-Slater R,Nijhawan A,Verghese E,Treanor D

更新日期：2018-03-01 00:00:00

abstract：AIMS:To examine 13 cases of mesothelioma with metastases and compare these with 29 biopsy samples of patients without metastases. Metastatic disease was defined as tumour in which tumour appeared in a different cavity/tissue of the body and which showed no direct spread. Consequently, mediastinal nodal and parenchymal ...

journal_title：Histopathology

authors： Lumb PD,Suvarna SK

更新日期：2004-04-01 00:00:00

abstract：:Two series of cutaneous malignant melanoma (CMM), one from a low incidence area (the Oxford Region) and one from a high incidence area (Western Australia), were compared by one pathologist using the same histological criteria. The findings included similarities in the distributions of histogenetic type of CMM, predomi...

journal_title：Histopathology

authors： Heenan PJ,Holman CD

更新日期：1982-11-01 00:00:00

abstract：AIMS:To assess the immunophenotypic changes associated with epithelial-mesenchymal transition (EMT) in endocervical adenocarcinoma, and correlate the findings with tumour morphology including growth pattern. METHODS AND RESULTS:Twenty-seven endocervical adenocarcinomas were studied using a panel of immunohistochemical...

journal_title：Histopathology

authors： Stewart CJ,Crook ML,Little L,Louwen K

更新日期：2011-04-01 00:00:00

abstract：AIMS:Biphenotypic sinonasal sarcoma (SNS) is a locally aggressive tumour that occurs in the sinonasal region. PAX3-MAML3 has recently been identified as a recurrent fusion gene event in this entity; however, a subset of tumours harbour alternative PAX3 rearrangement without the involvement of MAML3. In this study we so...

journal_title：Histopathology

authors： Fritchie KJ,Jin L,Wang X,Graham RP,Torbenson MS,Lewis JE,Rivera M,Garcia JJ,Schembri-Wismayer DJ,Westendorf JJ,Chou MM,Dong J,Oliveira AM

更新日期：2016-12-01 00:00:00

abstract：AIMS:Hepatocellular adenoma is an uncommon liver neoplasm and the studies of HCA subtypes have been primarily limited to France, United States and Japan. We aimed to describe the clinicopathologic features of hepatocellular adenoma subtypes in Turkey. METHODS AND RESULTS:The resection specimens of 59 cases diagnosed a...

journal_title：Histopathology

authors： Deniz K,Umetsu SE,Ferrell L,Yılmaz F,Güllüoğlu M,Sağol Ö,Bülbül Doğusoy G,Kırımlıoğlu H,Turhan N,Doran F,Kepil N,Çelikel ÇA,Nart D,Özgüven BY,Ceyran B,Karadağ N,Kır G,Erden E,Yılmaz G,Akyol G

更新日期：2021-01-06 00:00:00

abstract：:Aberrant crypt foci (ACF) have been identified in the methylene-blue stained mucosa of the human colon. Some lines of evidence suggest that ACF may be precursors of colon cancer. The objective of the present study was to establish morphological criteria able to define and classify ACF in histological sections. Twenty-...

journal_title：Histopathology

authors： Di Gregorio C,Losi L,Fante R,Modica S,Ghidoni M,Pedroni M,Tamassia MG,Gafà L,Ponz de Leon M,Roncucci L

更新日期：1997-04-01 00:00:00

abstract：AIMS:Histological grade is one of the most important prognostic factors in breast carcinomas, but poorly differentiated neoplasms still have quite heterogeneous biological behaviour, since they can be genetically classified as basal-like, HER2+ or even luminal. The aim was to analyse the frequency of oestrogen receptor...

journal_title：Histopathology

authors： Fernandes RC,Bevilacqua JL,Soares IC,Siqueira SA,Pires L,Hegg R,Carvalho FM

更新日期：2009-09-01 00:00:00

abstract：:The published literature is awash with examples of new tissue biomarkers promising to predict responses to therapy in breast cancer patients. However, few, if any, of these progress from the laboratory to the clinic. In this review we discuss some of the reasons for this, illustrating our discussion with a selection o...

journal_title：Histopathology

authors： Faratian D,Bartlett J

更新日期：2008-01-01 00:00:00

abstract：AIMS:Eleven cases of cutaneous perineurioma were studied to further characterize the histological features of this entity. METHODS AND RESULTS:The histological and immunocytochemical features of 11 cases of cutaneous perineurioma were studied and detailed by two pathologists. Clinical data were obtained from the refer...

journal_title：Histopathology

authors： Robson AM,Calonje E

更新日期：2000-10-01 00:00:00

abstract：AIM:We describe the unusual association of fallopian tubal prolapse and herpetic infection, an occurrence not previously reported to our knowledge. METHODS AND RESULTS:A 37-year-old woman presented with a small polypoid mass of the vaginal vault, 3 months after abdominal hysterectomy and abdominoplasty. The vaginal ma...

journal_title：Histopathology

authors： Lefrancq T,Orain I,Michalak S,Hourseau M,Fetissof F

更新日期：1999-06-01 00:00:00

abstract：AIMS:Mesenchyme forkhead 1 (FoxC2) is an epithelial-mesenchymal transition (EMT)-inducing factor. Previous studies have demonstrated that FoxC2 binds directly to the promoter region of p120-catenin (p120ctn). The aim of this study was to investigate the clinical significance of FoxC2 expression and the inter-relationsh...

journal_title：Histopathology

authors： Zhu JL,Song YX,Wang ZN,Gao P,Wang MX,Dong YL,Xing CZ,Xu HM

更新日期：2013-06-01 00:00:00

abstract：AIMS:Colonic and rectal biopsies, often taken from an endoscopically normal large bowel, form a significant proportion of the histopathology workload. The aim of this study was to determine diagnostic yield from mucosal biopsies in patients with normal colonoscopy or sigmoidoscopy, and whether or not diarrhoea is predi...

journal_title：Histopathology

authors： O'Mahony OH,Burgoyne M,Going JJ

更新日期：2012-12-01 00:00:00

abstract：AIMS:Although delayed hypopituitarism is a common complication of conventional radiotherapy of sellar tumours, histological changes that may account for it have been rarely reported. To elucidate the changes, hypofunctional pituitary glands following irradiation were studied. METHODS AND RESULTS:Two pituitary glands o...

journal_title：Histopathology

authors： Nishioka H,Ito H,Haraoka J,Hirano A

更新日期：2001-06-01 00:00:00

abstract：:Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

journal_title：Histopathology

authors： Browne RM,Rippin JW

更新日期：1984-11-01 00:00:00

abstract：:Three cases are reported in which an initial diagnosis of the plasma cell variant of Castleman's disease was made, but in which a second lymph node biopsy within a year showed evidence of Hodgkin's disease. Review of the initial biopsy indicated that atypical CD15 and CD30 positive cells were present in the initial bi...

journal_title：Histopathology

authors： Maheswaran PR,Ramsay AD,Norton AJ,Roche WR

更新日期：1991-03-01 00:00:00

abstract：:Increasingly more coherent data on the molecular characteristics of benign breast lesions and breast cancer precursors have led to the delineation of new multistep pathways of breast cancer progression through genotypic-phenotypic correlations. It has become apparent that oestrogen receptor (ER)-positive and -negative...

journal_title：Histopathology

authors： Lopez-Garcia MA,Geyer FC,Lacroix-Triki M,Marchió C,Reis-Filho JS

更新日期：2010-08-01 00:00:00

abstract：AIMS:There is controversy regarding the use of adjuvant therapy in patients with Dukes' B colorectal cancer (CRC). New markers, identifying high-risk Dukes' B patients, are needed. Here, we examine the utility of Raf kinase inhibitor protein (RKIP) as such a marker and promoter methylation as a mechanism of RKIP down-r...

journal_title：Histopathology

authors： Doyle B,Hagan S,Al-Mulla F,Scott L,Harden S,Paul J,Mulcahy H,Murray GI,Sheahan K,O'Sullivan J,Kolch W

更新日期：2013-02-01 00:00:00

abstract：:One hundred and twenty-six radial scars and complex sclerosing lesions from 91 women were examined to determine the incidence of and the clinical and pathological factors associated with the development of carcinoma and atypical hyperplasia within them. There was a clear relationship between the presence of carcinoma ...

journal_title：Histopathology

authors： Sloane JP,Mayers MM

更新日期：1993-09-01 00:00:00

abstract：:A review of 1818 patients with cutaneous malignant melanoma revealed that for both patients with localized disease (clinical stage I) and those with regional lymph node metastases at first presentation (clinical stage II), ulceration of the primary lesion was a poor prognostic sign. Although ulcerated lesions tended t...

journal_title：Histopathology

authors： McGovern VJ,Shaw HM,Milton GW,McCarthy WH

更新日期：1982-07-01 00:00:00

abstract：AIMS:Residual cancer morphology in radical prostatectomies (RPs) after neoadjuvant hormone therapy includes inconspicuous cytology, and treated tumour cells can be difficult to identify in lymph nodes. The aim of this study was to evaluate the role of immunohistochemistry (IHC) in identifying occult lymph node metastas...

journal_title：Histopathology

authors： Kehr E,Masry P,Lis R,Loda M,Taplin ME,Hirsch MS

更新日期：2016-01-01 00:00:00

abstract：AIMS:The diagnosis of polymorphous low-grade adenocarcinoma (PLGA) remains difficult for general pathologists, particularly in cases of small biopsy samples. We aimed to characterize the histopathological spectrum and immunohistochemical aspects by using an accessible immunohistochemical panel of cytoskeletal proteins ...

journal_title：Histopathology

authors： Sedassari BT,Dos Santos HT,Pigatti FM,Martins Mussi MC,Tobouti PL,Altemani A,Sousa S

更新日期：2016-06-01 00:00:00

abstract：AIMS:The majority of patients with Down syndrome (DS), trisomy 21, have morphologically abnormal thymuses and present with intrinsic immunological abnormalities affecting mainly the cellular immune response. The aim of this study was to examine whether the expression of functionally important molecules is altered in th...

journal_title：Histopathology

authors： Tomaru U,Tsuji T,Kiuchi S,Ishizu A,Suzuki A,Otsuka N,Ito T,Ikeda H,Fukasawa Y,Kasahara M

更新日期：2015-08-01 00:00:00

abstract：:Advances in modern chemotherapy and targeted treatments have resulted in lengthened survival in a variety of tumour types in the last decade. Increasingly in the 21st century, postchemotherapy resections are considered as a possible mode of treatment. Due to their exquisite chemosensitivity, resection of postchemother...

journal_title：Histopathology

authors： Berney DM,Lu YJ,Shamash J,Idrees M

更新日期：2017-01-01 00:00:00

abstract：:The histopathological classification of ovarian surface epithelial carcinomas (referred to hereafter as 'ovarian carcinoma') has shifted over the past 10 years to reflect more clearly our understanding of molecular events during carcinogenesis. Ovarian carcinoma is no longer viewed as a single entity but as multiple d...

journal_title：Histopathology

authors： Gurung A,Hung T,Morin J,Gilks CB

更新日期：2013-01-01 00:00:00

abstract：:Thirty-two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries ...

journal_title：Histopathology

authors： Miller N,Bédard YC,Cooter NB,Shaul DL

更新日期：1986-07-01 00:00:00

abstract：AIMS:To analyse expression and distribution of vascular endothelial growth factor (VEGF-C1), podocalyxin and synaptopodin within renal tissue in nephrotic syndrome glomerulopathies in children. METHODS AND RESULTS:Renal biopsies performed at the time and in the manner recommended by the World Health Organization. The ...

journal_title：Histopathology

authors： Ostalska-Nowicka D,Zachwieja J,Nowicki M,Kaczmarek E,Siwinska A,Witt M

更新日期：2005-02-01 00:00:00

abstract：:To our knowledge, the in situ phase of small cell lung carcinoma (SCLC) has not been reported previously although in situ/pre-invasive lesions are commonly observed in murine models. We report a patient diagnosed with SCLC presenting mostly as carcinoma in situ after photodynamic therapy (PDT) under the diagnosis of b...

journal_title：Histopathology

authors： Ota M,Nakatani Y,Nakajima T,Hiroshima K,Motoi N,Yoshino I,Ikeda JI

更新日期：2020-11-30 00:00:00