Pulmonary microinvasive small cell carcinoma with extensive in situ component identified after photodynamic therapy for 'squamous cell carcinoma in situ': A case report.

abstract：:High levels of bcl-2 protein have been found in a wide variety of human cancers. Since p53 gene inactivation occurs in over half of human cancers, it is possible that loss of p53-mediated repression of bcl-2 gene expression accounts, at least in part, for the frequent abnormalities in bcl-2 protein production seen in ...

journal_title：Histopathology

authors： Harn HJ,Ho LI,Liu CA,Liu GC,Lin FG,Lin JJ,Chang JY,Lee WH

更新日期：1996-04-01 00:00:00

abstract：:An immunocytochemical and cytophotometrical analysis of 30 renal cell carcinomas was carried out in order to investigate the expression of cytokeratin and vimentin in relation to the ploidy and mitotic index. Thirty renal cell carcinomas were studied using monoclonal antibodies CAM 5.2 and anti-vimentin in a biotin-st...

journal_title：Histopathology

authors： Dierick AM,Praet M,Roels H,Verbeeck P,Robyns C,Oosterlinck W

更新日期：1991-04-01 00:00:00

abstract：AIMS:To discern the differences in expression profiling of two histological subtypes of colorectal carcinoma (CRC) arising from the serrated route (serrated adenocarcinoma (SAC) and CRC showing histological and molecular features of a high level of microsatellite instability (hmMSI-H) both sharing common features (fema...

journal_title：Histopathology

authors： García-Solano J,Turpin-Sevilla MDC,García-García F,Carbonell-Muñoz R,Torres-Moreno D,Conesa A,Conesa-Zamora P

更新日期：2019-10-01 00:00:00

abstract：AIMS:To characterize the clinicopathological features and biological potential of a group of soft tissue lesions with morphology intermediate between intramuscular myxoma and low-grade myxofibrosarcoma. METHODS AND RESULTS:Thirty-eight lesions in 37 patients were retrieved from the authors' consultation files. Clinica...

journal_title：Histopathology

authors： van Roggen JF,McMenamin ME,Fletcher CD

更新日期：2001-09-01 00:00:00

abstract：AIMS:Most primary gastrointestinal lymphomas are of B-cell origin and T-cell origin is very rare. Recent studies have suggested that human T-cell lymphotrophic virus type 1 (HTLV-1) may be involved in the development of primary gastric T-cell lymphoma. We analysed 31 patients with primary gastric T-cell lymphoma in sou...

journal_title：Histopathology

authors： Hatano B,Ohshima K,Katoh A,Kanda M,Kawasaki C,Tsuchiya T,Shimazaki K,Haraoka S,Sugihara M,Suzumiya J,Kikuchi M

更新日期：2002-11-01 00:00:00

abstract：AIMS:Hodgkin lymphoma treatments are largely based on the generation of reactive oxygen species, but increased expression of antioxidant enzymes may contribute to chemoresistance. The aims of this study were: to define the extent and prognostic value of oxidative stress marker and antioxidant enzyme expression in Hodgk...

journal_title：Histopathology

authors： Bur H,Haapasaari KM,Turpeenniemi-Hujanen T,Kuittinen O,Auvinen P,Marin K,Koivunen P,Sormunen R,Soini Y,Karihtala P

更新日期：2014-09-01 00:00:00

abstract：:An immunohistochemical study of non-small cell lung carcinoma using PC10, a monoclonal antibody against PCNA, was performed on tissues routinely processed with formalin fixation and paraffin embedding. The PCNA labelling index and mitotic index were determined from sections of these tissues. Tumours showed a high mean...

journal_title：Histopathology

authors： Theunissen PH,Leers MP,Bollen EC

更新日期：1992-03-01 00:00:00

abstract：AIMS:To characterise the mutational profiles of poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) and to identify markers with potential diagnostic, prognostic and therapeutic significance. METHODS AND RESULTS:Targeted next-generation sequencing with a panel of 18 thyroid carcinoma-...

journal_title：Histopathology

authors： Duan H,Li Y,Hu P,Gao J,Ying J,Xu W,Zhao D,Wang Z,Ye J,Lizaso A,He Y,Wu H,Liang Z

更新日期：2019-12-01 00:00:00

abstract：:The ultrastructure of stromal mononuclear cells and giant cells were studied in two cases of central giant cell granuloma of the jaws. The majority of stromal cells superficially resembled fibroblasts, but also contained intracytoplasmic myofilaments with electron dense bodies similar to smooth muscle cells. These cel...

journal_title：Histopathology

authors： El-Labban NG,Lee KW

更新日期：1983-11-01 00:00:00

abstract：AIMS:Telomerase is reactivated in most cancers and there is accumulating evidence that this is a driver event in malignant melanoma (MM). Thus, our aim was to evaluate if in-situ hybridization (ISH)-based quantification of telomerase RNA (hTR) could be used to distinguish MM from naevi, and if there was a correlation w...

journal_title：Histopathology

authors： Vagner J,Steiniche T,Stougaard M

更新日期：2015-04-01 00:00:00

abstract：:We present a 27-year-old woman with non-systemic diffuse lymphangiomatosis of spleen and liver. The tumour consisted of capillary and cavernous lymphatic vessels located in abundant fibrous tissue. The vascular endothelium showed immunoreactivity for factor VIII-related antigen. A basal lamina could be demonstrated im...

journal_title：Histopathology

authors： Schmid C,Beham A,Uranüs S,Melzer G,Auböck L,Seewann HL,Klimpfinger M

更新日期：1991-05-01 00:00:00

abstract：:A male infant was diagnosed as having diabetes mellitus 1 d after birth and died on the third day. Histological examination of the pancreas showed small and inconspicuous islets of Langerhans that were completely devoid of insulin-secreting cells. There was no evidence of insulitis. ...

journal_title：Histopathology

authors： Wong KC,Tse K,Chan JK

更新日期：1988-05-01 00:00:00

abstract：:The clinical and pathological features of three adnexal tumours of probable Wolffian origin are reported. One case was an incidental finding in a patient who died from ovarian carcinoma; in the other two cases the patients presented with lower abdominal pain. The three tumours were well-circumscribed, solid masses ari...

journal_title：Histopathology

authors： Rahilly MA,Williams AR,Krausz T,al Nafussi A

更新日期：1995-01-01 00:00:00

abstract：:Signet ring cell differentiation in adenocarcinoma of the prostate is uncommon. In a review of 200 cases of prostatic carcinoma, we identified five cases with this change, all in moderately to poorly differentiated prostatic carcinomas. The signet ring cells in prostatic carcinoma contain an intracytoplasmic lumen, sh...

journal_title：Histopathology

authors： Guerin D,Hasan N,Keen CE

更新日期：1993-04-01 00:00:00

abstract：AIMS:We aimed to define the clinicopathological characteristics of 29 primary sinonasal diffuse large B cell lymphoma (DLBCLsn ) in a series of 240 cases of DLBCL not otherwise specified [DLBCLall (NOS) ], including DLBCLsn training set (n = 11) and validation set (n = 18), and DLBCLnon-sn (n = 211). METHODS AND RESUL...

journal_title：Histopathology

authors： Carreras J,Kikuti YY,Beà S,Miyaoka M,Hiraiwa S,Ikoma H,Nagao R,Tomita S,Martin-Garcia D,Salaverria I,Sato A,Ichiki A,Roncador G,Garcia JF,Ando K,Campo E,Nakamura N

更新日期：2017-03-01 00:00:00

abstract：:The expression of cytokeratin intermediate filaments by a tumour has been accepted as evidence of an epithelial origin. Although there have been anecdotal reports of cytokeratin expression within tissues and neoplasms of non-epithelial origin, particularly muscle, there have been no comprehensive studies of its freque...

journal_title：Histopathology

authors： Brown DC,Theaker JM,Banks PM,Gatter KC,Mason DY

更新日期：1987-05-01 00:00:00

abstract：AIMS:To verify the applicability, reproducibility and predictive value of a proposed unified classification (amended Ljubljana classification) for laryngeal squamous intraepithelial lesions (SILs). METHODS AND RESULTS:Six internationally recognized experts and three pathologists from Ljubljana contributed to this stud...

journal_title：Histopathology

authors： Gale N,Blagus R,El-Mofty SK,Helliwell T,Prasad ML,Sandison A,Volavšek M,Wenig BM,Zidar N,Cardesa A

更新日期：2014-10-01 00:00:00

abstract：:One hundred cases of routinely fixed and processed non-Hodgkin's lymphoma from Nigeria were immunostained with a small panel of monoclonal antibodies against B-, T- and macrophage antigens. The aims of the study were to assess the suitability of stored material from a country like Nigeria for immunohistochemical exami...

journal_title：Histopathology

authors： Thomas JO,Rafindadi A,Heryet A,Jones M,Gatter KC,Mason DY

更新日期：1991-06-01 00:00:00

abstract：:Recently, great interest has been shown in the histological identification of small cell tumours of childhood--nephroblastoma (Wilms' tumour), neuroblastoma, rhabdomyosarcoma and Ewing's sarcoma--using immunohistochemical methods. However, several antigens operationally specific for leucocyte typing in blood and marro...

journal_title：Histopathology

authors： Pilkington GR,Pallesen G

更新日期：1989-04-01 00:00:00

abstract：AIMS:Rheumatoid arthritis (RA) and pigmented villonodular synovitis (PVNS) are aggressive diseases with progressive joint destruction. The present study aims to define cell cycle phases, polyploidy and the immunophenotype of proliferating synovial cells in both diseases. METHODS AND RESULTS:Synovial tissues from patie...

journal_title：Histopathology

authors： Berger I,Weckauf H,Helmchen B,Ehemann V,Penzel R,Fink B,Bernd L,Autschbach F

更新日期：2005-05-01 00:00:00

abstract：:A procedure for the simultaneous fixation and decalcification of bone biopsies is described. Mild acidic fixatives (such as Bouin's fluid) are effective decalcifying agents when made calcium-free by a continuous circulation through a column of anion-binding ion exchange resin. The procedure has been found relatively f...

journal_title：Histopathology

authors： Bussolati G

更新日期：1978-09-01 00:00:00

abstract：:A cytokeratin immunohistochemical study was performed on 38 liver biopsies from cases of primary biliary cirrhosis, primary sclerosing cholangitis, extrahepatic biliary obstruction or drug-induced liver disease in order to analyse the cytoskeletal changes in detail. On paraffin sections of 27 cases, a variable number ...

journal_title：Histopathology

authors： Van Eyken P,Sciot R,Desmet VJ

更新日期：1989-08-01 00:00:00

abstract：:Fifteen hamartomas of the breast have been studied by dissecting microscopy of thick sections at a depth of 1.0 to 2.5 mm, and by conventional 5 microns deep sections. This combined approach has revealed six distinctive features, three in the parenchymal structure and three in the connective tissue components. Ducts (...

journal_title：Histopathology

authors： Davies JD,Kulka J,Mumford AD,Armstrong JS,Wells CA

更新日期：1994-02-01 00:00:00

abstract：AIMS:Lectins, and especially galectins, appear to be important in malignancy-associated processes. The aim was to analyse comprehensively the presence of galectins in urothelial tumours. METHODS AND RESULTS:Non-cross-reactive antibodies against seven family members from the three subgroups (prototype: galectin-1, -2 a...

journal_title：Histopathology

authors： Langbein S,Brade J,Badawi JK,Hatzinger M,Kaltner H,Lensch M,Specht K,André S,Brinck U,Alken P,Gabius HJ

更新日期：2007-11-01 00:00:00

abstract：AIMS:Although many immunohistochemical (IHC) cancer biomarkers have been identified, very few have translated into routine clinical practice, primarily because of technical and observational inconsistencies between studies. However, despite the obvious need to address such variability, very few studies have done so. M...

journal_title：Histopathology

authors： Lawrie CH,Ballabio E,Soilleux E,Sington J,Hatton CS,Dirnhofer S,Tzankov A

更新日期：2012-07-01 00:00:00

abstract：:The use of percutaneous renal tumour biopsy (RTB) as a diagnostic tool for the histological characterization of renal masses has increased dramatically within the last 30 years. This increased utilization has paralleled advances in imaging techniques and an evolving knowledge of the clinical value of nephron sparing s...

journal_title：Histopathology

authors： Delahunt B,Samaratunga H,Martignoni G,Srigley JR,Evans AJ,Brunelli M

更新日期：2014-09-01 00:00:00

abstract：AIMS:An increased risk of adenocarcinoma of the oesophagus has been demonstrated in patients with long segments of Barrett's mucosa. The risk of cancer associated with short segments of metaplasia of the oesophagogastric junction is not known. METHODS AND RESULTS:We report a case of early adenocarcinoma of the oesopha...

journal_title：Histopathology

authors： Santacroce CM,Fléjou JF

更新日期：1997-07-01 00:00:00

abstract：AIMS:To investigate the protein expressions of breast cancer 1 (BRCA1) and 2 (BRCA2) in prostatectomy specimens of localized prostate cancer (PC) patients, along with their associations with cancer characteristics and prognosis. METHODS AND RESULTS:Immunohistochemistry for BRCA1 and BRCA2 was performed on tissue micro...

journal_title：Histopathology

authors： Kim SH,Park WS,Yun SI,Joo J,Joung JY,Seo HK,Chung J,Lee GK,Lee KH

更新日期：2016-04-01 00:00:00

abstract：AIMS:To survey current European practices in handling and reporting of radical prostatectomy (RP) specimens. METHODS AND RESULTS:A European Network of Uropathology (ENUP) was organized for the dissemination of information, survey studies and research collaborations. Contact data of uropathologists were collected from ...

journal_title：Histopathology

authors： Egevad L,Algaba F,Berney DM,Boccon-Gibod L,Griffiths DF,Lopez-Beltran A,Mikuz G,Varma M,Montironi R,European Network of Uropathology.

更新日期：2008-09-01 00:00:00

abstract：AIMS:To examine the immunohistochemical expression of helicase-like transcription factor (HLTF) in relation to the prognosis of hypopharyngeal (HSCCs) and laryngeal (LSCCs) squamous cell carcinomas, and to characterize the HLTF protein variants expressed in biopsy specimens of head and neck squamous cell carcinoma (HNS...

journal_title：Histopathology

authors： Capouillez A,Debauve G,Decaestecker C,Filleul O,Chevalier D,Mortuaire G,Coppée F,Leroy X,Belayew A,Saussez S

更新日期：2009-07-01 00:00:00