Evaluation of a new grading system for laryngeal squamous intraepithelial lesions--a proposed unified classification.

abstract：AIMS:Adenoid cystic carcinoma (AdCC) of the salivary glands shows heterogeneous behaviour, with metastasis as a key indicator of poor prognosis. Metallothionein (MT) expression has been associated with poor prognosis of diverse neoplasms. We evaluated prognostic factors for AdCC and the role played by MT, focusing on m...

journal_title：Histopathology

authors： Brazão-Silva MT,Cardoso SV,de Faria PR,Dias FL,Lima RA,Eisenberg AL,Nascimento MF,Loyola AM

更新日期：2013-12-01 00:00:00

abstract：:A series of 115 consecutive, non-ulcerous, dyspeptic patients were examined for Helicobacter pylori (H. pylori) colonization in the gastric antral and/or body mucosa using Giemsa staining. Findings were correlated with the presence and degree of activity of superficial gastritis, deep gastritis, atrophic gastritis and...

journal_title：Histopathology

authors： Rugge M,Di Mario F,Cassaro M,Baffa R,Farinati F,Rubio J Jr,Ninfo V

更新日期：1993-01-01 00:00:00

abstract：:Delta hepatitis (HDV) infection can only occur in the presence of hepatitis B (HBV) infection, as HDV requires a coat of HBV surface antigen (HBsAg) for assembly of complete virus. A number of studies have examined the variation of HBV markers in serum and liver during establishment of HDV infection, but none has syst...

journal_title：Histopathology

authors： Ryley NG,Heryet AR,Goldin R,Monjardino J,Saldanha J,Fleming KA

更新日期：1992-04-01 00:00:00

abstract：AIMS:To evaluate the relationship between phenotypic expression and tumour progression as represented by macroscopic features, submucosal invasion and lymph node metastasis in early differentiated gastric adenocarcinoma. METHODS:One hundred and fifty-five cases of early gastric differentiated adenocarcinoma without an...

journal_title：Histopathology

authors： Nakamura T,Yao T,Kabashima A,Nishiyama K,Maehara Y,Tsuneyoshi M

更新日期：2005-10-01 00:00:00

abstract：:The numbers of IgA, IgM and IgG-containing cells were studied by means of an indirect immunoperoxidase technique and morphometry in liver biopsies of patients with primary biliary cirrhosis and chronic hepatitis, in whom serum immunoglobulin concentrations were also determined. In patients with primary biliary cirrhos...

journal_title：Histopathology

authors： Van Spreeuwel JP,Van Gorp LH,Nadorp JH,Janssens AR,Lindeman J,Meijer CJ

更新日期：1984-07-01 00:00:00

abstract：AIMS:Spermatocytic seminoma is a rare germ cell derived tumour of the testis that occurs mainly in older men. We analysed the expression of recently discovered markers for germ cell differentiation and the mitosis-meiosis transition in order to define the antigen profile for diagnostic purposes and to clarify the biolo...

journal_title：Histopathology

authors： Rajpert-De Meyts E,Jacobsen GK,Bartkova J,Aubry F,Samson M,Bartek J,Skakkebaek NE

更新日期：2003-03-01 00:00:00

abstract：:Ultrastructural appearances of a small intestinal inflammatory fibroid polyp are reported. There is a vascular scaffolding, with interstices which contain regular and fibrous long-spacing type collagen, condensed lamellar basement membrane fibroblasts, basophils, some eosinophils and histiocytes. In addition other cel...

journal_title：Histopathology

authors： Williams RM

更新日期：1981-03-01 00:00:00

abstract：:The treatment of cancer has changed dramatically over the last decade, driven by increased understanding of the cancer genome, immune landscape, molecular alterations and aberrant pathways that drive cancer progression. Advances in molecular biology have led to the development of targeted agents, including monoclonal ...

journal_title：Histopathology

authors： Crusz SM,Miller RE

更新日期：2020-01-01 00:00:00

abstract：AIMS:To study whether coexpression of the two hypoxia-related proteins hypoxia-inducible factor (HIF)-1α and glucose transporter (GLUT)-1 has prognostic relevance in oral squamous cell carcinomas (OSCCs). METHODS AND RESULTS:Eighty-two OSCC samples were analysed for expression levels of HIF-1α and GLUT-1 by immunohist...

journal_title：Histopathology

authors： Eckert AW,Lautner MH,Schütze A,Taubert H,Schubert J,Bilkenroth U

更新日期：2011-06-01 00:00:00

abstract：AIMS:Pathological or neuroprotective mechanisms in the brain in severe malaria may arise from microvascular obstruction with malaria-parasitized erythrocytes. This study aimed to investigate the role of hypoxia and induction of the vascular endothelial growth factor (VEGF) pathway in the neuropathophysiology of severe ...

journal_title：Histopathology

authors： Medana IM,Day NP,Roberts R,Sachanonta N,Turley H,Pongponratn E,Hien TT,White NJ,Turner GD

更新日期：2010-08-01 00:00:00

abstract：AIMS:To determine the expression of matrix metalloproteinases (MMPs)-2, -7 and -9 and beta-catenin in uterine serous carcinoma (USC) and endometrioid endometrial carcinoma (EEC) and to investigate any difference in expression between EEC and USC which might explain the mechanism of invasion and aggressive behaviour of ...

journal_title：Histopathology

authors： Monaghan H,MacWhinnie N,Williams AR

更新日期：2007-02-01 00:00:00

abstract：AIMS:SMAD4 acts as a tumour suppressor, and the loss of SMAD4 is associated with poor prognosis in colorectal cancer (CRC) patients. Although next-generation sequencing (NGS) enabled us to detect numerous genetic alterations in a single assay, the clinical significance of SMAD4 alteration detected with NGS has not been...

journal_title：Histopathology

authors： Oyanagi H,Shimada Y,Nagahashi M,Ichikawa H,Tajima Y,Abe K,Nakano M,Kameyama H,Takii Y,Kawasaki T,Homma KI,Ling Y,Okuda S,Takabe K,Wakai T

更新日期：2019-05-01 00:00:00

abstract：AIMS:Monocarboxylate transporters (MCTs) have been considered promising targets for cancer therapy, since they facilitate lactate efflux in glycolytic tumours. However, their role in solid tumours is still poorly understood. Thus, the present work aimed to contribute to understanding the involvement of MCT1 and MCT4 in...

journal_title：Histopathology

authors： Pinheiro C,Albergaria A,Paredes J,Sousa B,Dufloth R,Vieira D,Schmitt F,Baltazar F

更新日期：2010-06-01 00:00:00

abstract：AIMS:HER2 testing of invasive breast cancer by in-situ hybridization guides therapy decisions. Probing HER2 and centromere of chromosome 17 (cen17) simultaneously is supposed to reveal both a potential HER2 gene amplification and polysomy 17. However, a considerable number of breast cancer patients with quasi polysomy ...

journal_title：Histopathology

authors： Holzschuh MA,Czyz Z,Hauke S,Inwald EC,Polzer B,Brockhoff G

更新日期：2017-10-01 00:00:00

abstract：AIMS:We report the clinicopathological and immunohistochemical characteristics of 12 cases of a recently recognized entity, oncocytic papillary thyroid carcinoma (PC) with lymphoid stroma (Warthin-like tumour). METHODS AND RESULTS:The cases were retrieved from the surgical pathology files of our departments. There wer...

journal_title：Histopathology

authors： Ludvíková M,Ryska A,Korabecná M,Rydlová M,Michal M

更新日期：2001-07-01 00:00:00

abstract：:The relationship between proliferating cell nuclear antigen (PCNA) expression and various clinicopathological indices (age, sex, tumour location, histological type and grade and treatment) and post-operative survival were studied in patients with central nervous system gliomas using univariate and multivariate analysi...

journal_title：Histopathology

authors： Korkolopoulou P,Christodoulou P,Lekka-Katsouli I,Kouzelis K,Papanikolaou A,Panayotides I,Mariatos P,Thomas-Tsagli E,Crocker J

更新日期：1994-10-01 00:00:00

abstract：:Granulomatous prostatitis may result from tuberculosis and fungal infection and has been described following prostatic surgery. In most cases, however, the aetiology is unknown, although it may be due to a reaction to extravasated or altered prostatic secretions. We have investigated cells (macrophages, lymphocytes), ...

journal_title：Histopathology

authors： Dhundee J,Maciver AG

更新日期：1991-05-01 00:00:00

abstract：:A malignant rhabdoid tumour of the bladder is reported from a girl aged 6. Detailed immunohistochemical and ultrastructural investigations provide evidence which suggests a histiocytic origin for this controversial neoplasm. ...

journal_title：Histopathology

authors： Carter RL,McCarthy KP,al-Sam SZ,Monaghan P,Agrawal M,McElwain TJ

更新日期：1989-02-01 00:00:00

abstract：AIMS:BCOR-CCNB3 sarcoma is a genetically defined undifferentiated malignancy with Ewing sarcoma (ES)-like round cells, and preferentially affects the bones of male adolescents. Sarcomas harbouring BCOR-CCNB3 rarely arise from soft tissues; therefore, we aimed to report four cases to expand the clinicopathological spect...

journal_title：Histopathology

authors： Li WS,Liao IC,Wen MC,Lan HH,Yu SC,Huang HY

更新日期：2016-11-01 00:00:00

abstract：AIMS:Early recognition and accurate diagnosis underpins melanoma survival. Identifying early melanomas arising in association with pre-existing lesions is often challenging. Clinically suspicious foci, however small, must be identified and examined histologically. This study assessed the accuracy of punch biopsy 'scori...

journal_title：Histopathology

authors： Grogan J,Cooper CL,Dodds TJ,Guitera P,Menzies SW,Scolyer RA

更新日期：2018-01-01 00:00:00

abstract：:Two cases of pedunculated hepatocellular carcinoma are reported. One of these was known to have been present for 5 years. Both patients are alive 1 and 2 years after surgery though the former has developed a solitary bone metastasis. The literature on 30 previously published cases is reviewed and it is concluded that,...

journal_title：Histopathology

authors： Anthony PP,James K

更新日期：1987-04-01 00:00:00

abstract：AIMS:Rheumatoid arthritis (RA) and pigmented villonodular synovitis (PVNS) are aggressive diseases with progressive joint destruction. The present study aims to define cell cycle phases, polyploidy and the immunophenotype of proliferating synovial cells in both diseases. METHODS AND RESULTS:Synovial tissues from patie...

journal_title：Histopathology

authors： Berger I,Weckauf H,Helmchen B,Ehemann V,Penzel R,Fink B,Bernd L,Autschbach F

更新日期：2005-05-01 00:00:00

abstract：AIMS:To examine the usefulness of Hep Par 1 together with selected antibodies in the separation of hepatocellular carcinoma (HCC) from cholangiocarcinoma (CC), combined tumours (HCC-CC) and metastatic carcinoma. METHODS AND RESULTS:Antibodies to Hep Par 1, CK19, CK20 and factor XIIIa were applied to 32 HCCs, 27 CCs, f...

journal_title：Histopathology

authors： Leong AS,Sormunen RT,Tsui WM,Liew CT

更新日期：1998-10-01 00:00:00

abstract：AIMS:To investigate the clinicopathological and molecular features of primary effusion lymphoma (PEL) in Taiwan and the association with human immunodeficiency virus (HIV), human herpesvirus 8 (HHV8) and Epstein-Barr virus (EBV). METHODS AND RESULTS:We investigated retrospectively 26 cases with a median age of 76.5. O...

journal_title：Histopathology

authors： Chen BJ,Wang RC,Ho CH,Yuan CT,Huang WT,Yang SF,Hsieh PP,Yung YC,Lin SY,Hsu CF,Su YZ,Kuo CC,Chuang SS

更新日期：2018-05-01 00:00:00

abstract：AIMS:Telepathology uses digitised image transfer to allow off-site reporting of histopathology slides. This technology could facilitate the centralisation of pathology services, which may improve their quality and cost-effectiveness. The benefits may be most apparent in frozen section reporting, in which turnaround tim...

journal_title：Histopathology

authors： French JMR,Betney DT,Abah U,Bhatt N,Internullo E,Casali G,Batchelor TJP,West DG

更新日期：2019-05-01 00:00:00

abstract：:The so-called sclerosing haemangioma of the lung is an uncommon tumour with predilection for Chinese women. Twenty-five cases showed a predominantly solid/cellular pattern in three, a haemorrhagic/angiomatoid pattern in three, a papillary pattern in one, a sclerotic pattern in one, and in seventeen, a mixed pattern wa...

journal_title：Histopathology

authors： Leong AS,Chan KW,Seneviratne HS

更新日期：1995-08-01 00:00:00

abstract：AIMS:Previous karyotyping and fluorescence in situ hybridization analysis of metanephric adenomas (MAs) has yielded controversial data. The aim of this study was to detect small genomic alterations, if any, specific to MAs by applying high-resolution oligoarrays. METHODS AND RESULTS:DNA extracted from paraffin blocks ...

journal_title：Histopathology

authors： Szponar A,Yusenko MV,Kovacs G

更新日期：2010-01-01 00:00:00

abstract：:Some antigenic determinants can be preserved in tissues after plastic embedding. In the present study liver tissue was fixed with glutaraldehyde or paraformaldehyde, dehydrated with ethanol and toluene and embedded in araldite which was then polymerized at 37 degrees C. Immunofluorescence was performed on semi-thin se...

journal_title：Histopathology

authors： Scotto J

更新日期：1977-09-01 00:00:00

abstract：AIMS:NUT carcinoma, a rare aggressive tumor driven by NUTM1 rearrangements, often involves the lung/mediastinum and shows squamous differentiation. We encountered an index patient with a thoracic NUT carcinoma diagnosed by molecular testing, demonstrating extensive pleural involvement and diffuse TTF-1 expressions init...

journal_title：Histopathology

authors： Hung YP,Chen AL,Taylor MS,Huynh TG,Kem M,Selig MK,Nielsen GP,Lennerz JK,Azzoli CG,Dagogo-Jack I,Kradin RL,Mino-Kenudson M

更新日期：2020-11-24 00:00:00

abstract：AIM:Primary cutaneous neuroendocrine carcinoma, or Merkel cell carcinoma (MCC), cannot be distinguished morphologically from small-cell neuroendocrine carcinomas (SmCC) from other sites. Immunohistochemistry is required to confirm cutaneous origin, and is also used for detection of sentinel lymph node (SLN) metastases ...

journal_title：Histopathology

authors： Stanoszek LM,Chan MP,Palanisamy N,Carskadon S,Siddiqui J,Patel RM,Harms KL,Lowe L,Fullen DR,Harms PW

更新日期：2019-02-01 00:00:00