Quantitative, microscopical, computer-aided diagnosis of endometrial hyperplasia or carcinoma in individual patients.

abstract：:A rapidly fatal bladder tumour which had the features of a rhabdoid tumour was studied by sequential biopsies and at autopsy. This is the first rhabdoid tumour recorded at this site and the first in which there was co-existent transitional cell carcinoma. The possibility that rhabdoid tumour is histogenetically hetero...

journal_title：Histopathology

authors： Harris M,Eyden BP,Joglekar VM

更新日期：1987-10-01 00:00:00

abstract：AIMS:To evaluate the immunoexpression of cyclin A1 in pT1 urothelial carcinomas of the bladder (UC) from a cohort of patients treated by transurethral resection of the bladder (TURB), to determine its value in predicting tumour recurrence, tumour progression, or systemic metastases. METHODS AND RESULTS:Five tissue mic...

journal_title：Histopathology

authors： Munari E,Chaux A,Maldonado L,Compérat E,Varinot J,Bivalacqua TJ,Hoque MO,Netto GJ

更新日期：2015-01-01 00:00:00

abstract：AIMS:To discern the differences in expression profiling of two histological subtypes of colorectal carcinoma (CRC) arising from the serrated route (serrated adenocarcinoma (SAC) and CRC showing histological and molecular features of a high level of microsatellite instability (hmMSI-H) both sharing common features (fema...

journal_title：Histopathology

authors： García-Solano J,Turpin-Sevilla MDC,García-García F,Carbonell-Muñoz R,Torres-Moreno D,Conesa A,Conesa-Zamora P

更新日期：2019-10-01 00:00:00

abstract：:HLA-DR expression was examined in 50 consecutive primary cutaneous malignant melanomas with a Breslow depth greater than 2 mm using two well-characterized monoclonal antibodies which detect fixation-resistant epitopes. In 31 of these cases (62%) a subpopulation of tumour cells was reactive, although there was consider...

journal_title：Histopathology

authors： Colloby PS,West KP,Fletcher A

更新日期：1992-05-01 00:00:00

abstract：AIMS:In T cells, protein kinase C (PKC) theta plays a major role in T-cell receptor (TCR)-mediated activation of a novel nuclear factor (NF)-kappaB pathway that involves phosphorylation of p65 at serine 536 (Pp65(Ser536)). Bcl-10 acts along the same pathway downstream of PKC theta to activate NF-kappaB. The aim was to ...

journal_title：Histopathology

authors： Briones J,Moga E,Espinosa I,Vergara C,Alvarez E,Villa J,Bordes R,Delgado J,Prat J,Sierra J

更新日期：2009-03-01 00:00:00

abstract：:Fifteen cases of non-Hodgkin's lymphoma of the anterior mediastinum are reported. In the first group of four, fresh tissue was available and immunohistochemical studies demonstrated their B-cell origin, with monotypic immunoglobulin production in two. Only fixed tissue was available in the second group of 11 patients....

journal_title：Histopathology

authors： Addis BJ,Isaacson PG

更新日期：1986-04-01 00:00:00

abstract：:We report an example of what we believe to be an adenocarcinoma of the appendix testis. This very rare neoplasm arose in a patient on long term treatment with oestrogens which may be implicated as an aetiological factor. ...

journal_title：Histopathology

authors： Kernohan NM,Coutts AG,Best PV

更新日期：1990-08-01 00:00:00

abstract：:The detailed documentation of ocular pathology has become an important component in the autopsy investigation of suspected cases of non-accidental injury in infants and young children. Careful histological examination of retinal haemorrhages is of critical importance, but there remains debate about the significance of...

journal_title：Histopathology

authors： Gilliland MG,Luthert P

更新日期：2003-12-01 00:00:00

abstract：AIMS:Eleven cases of cutaneous perineurioma were studied to further characterize the histological features of this entity. METHODS AND RESULTS:The histological and immunocytochemical features of 11 cases of cutaneous perineurioma were studied and detailed by two pathologists. Clinical data were obtained from the refer...

journal_title：Histopathology

authors： Robson AM,Calonje E

更新日期：2000-10-01 00:00:00

abstract：AIMS:Diversion colitis (DC) is a localized, relatively benign, iatrogenic condition which occurs in almost 100% of diverted colonic segments in patients who undergo ileostomy/colostomy for various reasons. The aim of this study was to establish histological features of DC in children. METHODS AND RESULTS:Twenty-three ...

journal_title：Histopathology

authors： Vujanić GM,Dojcinov SD

更新日期：2000-01-01 00:00:00

abstract：AIMS:Small cell (neuroendocrine) carcinoma of the urinary bladder is clinically more aggressive than urothelial (transitional cell) carcinoma. We have investigated the immunohistochemical markers most useful in diagnosing small cell carcinoma in bladder. METHODS AND RESULTS:We evaluated the expression of chromogranin ...

journal_title：Histopathology

authors： Iczkowski KA,Shanks JH,Allsbrook WC,Lopez-Beltran A,Pantazis CG,Collins TR,Wetherington RW,Bostwick DG

更新日期：1999-08-01 00:00:00

abstract：:Apoptotic bodies were investigated ultrastructurally in 10 cases of squamous cell carcinoma taken from buccal mucosa, tongue and larynx. Epithelial cells undergoing mitosis were found to show premature formation of nuclear membranes around various aggregates of chromosomal material giving the appearance of micronuclei...

journal_title：Histopathology

authors： el-Labban NG,Osorio-Herrera E

更新日期：1986-09-01 00:00:00

abstract：AIM:Alveolar capillary dysplasia (ACD) is a rare disorder, typically presenting with persistent pulmonary hypertension of the newborn. The aim was to characterise further the histological features of patients suspected of having ACD and to correlate histopathological features with outcome. METHODS AND RESULTS:Three pa...

journal_title：Histopathology

authors： Melly L,Sebire NJ,Malone M,Nicholson AG

更新日期：2008-10-01 00:00:00

abstract：AIMS:The study was undertaken to demonstrate wild-type p53 in normal paraffin-embedded tissues using two widely used antibodies, DO7 and 1801 and two different antigen retrieval buffer systems. METHODS AND RESULTS:Formalin-fixed paraffin-embedded normal tissue samples were obtained from the archives of the John Radcli...

journal_title：Histopathology

authors： Pillai G,Roberts H,Gatter K,Pezzella F

更新日期：2003-01-01 00:00:00

abstract：:Eight cases of myelosarcoma without acute leukaemia at time of diagnosis were reviewed and biopsies were immunostained using antibodies reacting with myeloid/monocytic markers. Initial tumour location included lymph nodes, paranasal sinuses, nasopharyngeal and/or orbital regions and other extranodal locations. Three c...

journal_title：Histopathology

authors： Furebring-Fredén M,Martinsson U,Sundström C

更新日期：1990-03-01 00:00:00

abstract：:While the histological grade of a renal cell carcinoma is of prognostic significance there is poor concordance amongst pathologists in the use of these grading systems. Many grading systems have been described, but none has achieved widespread acceptance. The objective of this study was to assess the degree of interob...

journal_title：Histopathology

authors： Lanigan D,Conroy R,Barry-Walsh C,Loftus B,Royston D,Leader M

更新日期：1994-05-01 00:00:00

abstract：AIMS:To assess KIT receptor tyrosine kinase and stem cell factor (SCF, KIT ligand) expression in tumour microvessel endothelial cells. METHODS AND RESULTS:KIT and SCF expression were studied in 248 human tumours consisting of 15 different histological types using immunohistochemistry and in situ hybridization for KIT ...

journal_title：Histopathology

authors： Sihto H,Tynninen O,Halonen M,Puputti M,Karjalainen-Lindsberg ML,Kukko H,Joensuu H

更新日期：2009-11-01 00:00:00

abstract：AIMS:To test the effectiveness of a teaching resource (a decision tree with diagnostic criteria based on published literature) in improving the proficiency of Gleason grading of prostatic cancer by general pathologists. METHODS:A decision tree with diagnostic criteria was developed by a panel of urological pathologist...

journal_title：Histopathology

authors： Griffiths DF,Melia J,McWilliam LJ,Ball RY,Grigor K,Harnden P,Jarmulowicz M,Montironi R,Moseley R,Waller M,Moss S,Parkinson MC

更新日期：2006-05-01 00:00:00

abstract：:One hundred and two cases of poorly differentiated adenocarcinoma were obtained from 71 surgical and 31 biopsy specimens of the stomach. These tumours produced both intracellular and extracellular mucins, which were demonstrated to be neutral mucins, N-acetyl sialomucins, sulphomucins and O-acetyl sialomucins. The maj...

journal_title：Histopathology

authors： Huang CB,Li WC,Xu J,Zhang YC

更新日期：1988-05-01 00:00:00

abstract：:Granular cell tumours rarely involve the lower respiratory tract. We report eight cases surgically resected at our institution. There were four females and four males, aged between 18 to 56 years (mean 40). One tumour associated with a peripheral lung adenocarcinoma was asymptomatic. The other lesions presented with o...

journal_title：Histopathology

authors： Thomas de Montpréville V,Dulmet EM

更新日期：1995-09-01 00:00:00

abstract：AIMS:Sixty new cases of human dirofilariasis due to Dirofilaria repens, occurring in Italy between 1990 and 1999, are presented. This is the most extensive case study of this zoonosis reported worldwide by a single study group. The aim is to utilize this large experience to characterize the different histopathological ...

journal_title：Histopathology

authors： Pampiglione S,Rivasi F,Angeli G,Boldorini R,Incensati RM,Pastormerlo M,Pavesi M,Ramponi A

更新日期：2001-04-01 00:00:00

abstract：AIMS:Metastatic melanoma involving the epidermis and/or upper dermis may show significant histological overlap with primary cutaneous melanoma, especially the nodular subtype. Proper histopathological classification is crucial to appropriate staging and management, but is often challenging. The aim of this study was to...

journal_title：Histopathology

authors： Skala SL,Arps DP,Zhao L,Cha KB,Wang M,Harms PW,Andea AA,Fullen DR,Chan MP

更新日期：2018-02-01 00:00:00

abstract：:Two cases of pedunculated hepatocellular carcinoma are reported. One of these was known to have been present for 5 years. Both patients are alive 1 and 2 years after surgery though the former has developed a solitary bone metastasis. The literature on 30 previously published cases is reviewed and it is concluded that,...

journal_title：Histopathology

authors： Anthony PP,James K

更新日期：1987-04-01 00:00:00

abstract：AIMS:Perineural invasion (PNI) by prostatic adenocarcinoma is debated as a prognostic parameter. This study investigates the prognostic predictive value of PNI in a series of patients with locally advanced prostate cancer treated with radiotherapy and androgen deprivation using 10 years outcome data from the TROG 03.04...

journal_title：Histopathology

authors： Delahunt B,Murray JD,Steigler A,Atkinson C,Christie D,Duchesne G,Egevad L,Joseph D,Matthews J,Oldmeadow C,Samaratunga H,Spry NA,Srigley JR,Hondermarck H,Denham JW

更新日期：2020-08-01 00:00:00

abstract：AIMS:The cadherin-catenin complex is known to play a critical role in maintenance of cell adhesion. Additionally beta-catenin (beta-ct) can also take part in signal transduction and nuclear beta-ct expression could be correlated with poor prognosis in several malignancies. Since, in gastric cancer, this role of beta-ct...

journal_title：Histopathology

authors： Grabsch H,Takeno S,Noguchi T,Hommel G,Gabbert HE,Mueller W

更新日期：2001-08-01 00:00:00

abstract：:Pulmonary typical carcinoid tumours are generally easy to diagnose with their uniform cells, carcinoid growth pattern and lack of mitoses. However, nuclear pleomorphism, which is common in other neuroendocrine tumours, is not emphasized in pulmonary carcinoid tumours. Three cases of typical carcinoid tumours, because ...

journal_title：Histopathology

authors： Sheppard MN

更新日期：1997-05-01 00:00:00

abstract：:In this study breast tissue that contained ultrastructural dense core granules has been examined from 24 patients. The possible neuroendocrine characteristics of the granules were studied using the uranaffin reaction and an ultrastructural argyrophil stain. The tissue included 15 breast carcinomas and nine benign samp...

journal_title：Histopathology

authors： Hopkinson HE,Battersby S,Anderson TJ

更新日期：1987-11-01 00:00:00

abstract：AIM:Although the World Health Organization (WHO) histological criteria distinguishing benign from atypical and malignant meningioma are clear, discerning benign from atypical meningioma is still somewhat difficult, leading to interobserver diagnostic variability. Osteopontin (OPN) and cortactin play important roles in ...

journal_title：Histopathology

authors： Lin CK,Tsai WC,Lin YC,Hueng DY

更新日期：2012-01-01 00:00:00

abstract：AIMS:There is evidence that four or five gastric cancer biopsies are required for accurate HER2 interpretation. However, the number of biopsies that need to be taken to reach this number of viable cancer biopsies is without evidence. This study aimed to address this gap by assessing the number of biopsies required to g...

journal_title：Histopathology

authors： Kaye P,Lindsay D,Madhusudan S,Vohra R,Catton J,Platt C,Ragunath K

更新日期：2019-05-01 00:00:00

abstract：:Anaplastic choroid plexus carcinoma is a tumour with a predilection for the posterior fossa of infants and can be difficult to distinguish histologically from medulloblastoma without the aid of immunocytochemistry using a panel of antibodies. Of a series of 17 choroid plexus carcinomas (five of which were classed as m...

journal_title：Histopathology

authors： Newbould MJ,Kelsey AM,Arango JC,Ironside JW,Birch J

更新日期：1995-02-01 00:00:00