Abstract:
:Apoptotic bodies were investigated ultrastructurally in 10 cases of squamous cell carcinoma taken from buccal mucosa, tongue and larynx. Epithelial cells undergoing mitosis were found to show premature formation of nuclear membranes around various aggregates of chromosomal material giving the appearance of micronuclei. These cells were also shown to exhibit changes in their cytoplasm different from those seen in normally dividing epithelial cells. The changes seen in both the nuclei and cytoplasm of these cells were similar to those observed in cells undergoing apoptosis. It is suggested from this study that some apoptotic bodies, especially those of epithelial cell origin, may result from degeneration affecting cells in abnormal mitosis.
journal_name
Histopathologyjournal_title
Histopathologyauthors
el-Labban NG,Osorio-Herrera Edoi
10.1111/j.1365-2559.1986.tb02590.xsubject
Has Abstractpub_date
1986-09-01 00:00:00pages
921-31issue
9eissn
0309-0167issn
1365-2559journal_volume
10pub_type
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