Counts of S-100 positive epidermal dendritic cells in Kveim test skin biopsies.

Abstract:

:S-100 positive epidermal dendritic cells were counted in skin biopsies from 48 Kveim tests and four known foreign-body reactions. Counts in histologically positive Kveim biopsies (mean 11.3 per 200 basal cells) were significantly higher than in either negative biopsies (5.1; P less than 0.001) or foreign-body reactions (4.7; P less than 0.05). A similar difference was found, irrespective of the histological appearances, between biopsies from patients diagnosed clinically as having sarcoidosis (10.5) and those in which another diagnosis had been made (4.1; P less than 0.001). In biopsies from patients with sarcoidosis 70% had a positive Kveim test, 70% had a raised epidermal dendritic cell count and one or the other was positive in 90%. All cases in which both the Kveim test was positive and the dendritic cell count was raised had a final clinical diagnosis of sarcoidosis. Counts of S-100 positive epidermal dendritic cells are useful in differentiating positive reactions to Kveim suspension from non-specific reactions to foreign material and increase the diagnostic confidence of the Kveim test.

journal_name

Histopathology

journal_title

Histopathology

authors

Shaw PA,Fletcher A

doi

10.1111/j.1365-2559.1991.tb01457.x

subject

Has Abstract

pub_date

1991-02-01 00:00:00

pages

149-53

issue

2

eissn

0309-0167

issn

1365-2559

journal_volume

18

pub_type

杂志文章
  • The role of Helicobacter pylori in primary gastric MALT lymphoma.

    abstract:AIMS:Helicobacter pylori has been claimed to be an important aetiological factor which raises the risk of mucosa-associated tissue lymphoid (MALT) lymphoma. However, some studies on gastric MALT lymphoma revealed a low rate of H. pylori infection suggesting that not all gastric lymphomas are related to H. pylori infect...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.1999.00597.x

    authors: Bouzourene H,Haefliger T,Delacretaz F,Saraga E

    更新日期:1999-02-01 00:00:00

  • Mantle cell lymphoma: a clinicopathological study of 55 cases.

    abstract::A recently described unifying proposal for mantle cell lymphoma has led to the formulation of strict diagnostic criteria based on morphology, immunology and molecular data to define this specific entity. Previous studies were often based on broader definitions such as centrocytic lymphoma, intermediately differentiate...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1995.tb00615.x

    authors: Pittaluga S,Wlodarska I,Stul MS,Thomas J,Verhoef G,Cassiman JJ,Van den Berghe H,de Wolf-Peeters C

    更新日期:1995-01-01 00:00:00

  • Granular cell tumours of the lower respiratory tract.

    abstract::Granular cell tumours rarely involve the lower respiratory tract. We report eight cases surgically resected at our institution. There were four females and four males, aged between 18 to 56 years (mean 40). One tumour associated with a peripheral lung adenocarcinoma was asymptomatic. The other lesions presented with o...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1995.tb00218.x

    authors: Thomas de Montpréville V,Dulmet EM

    更新日期:1995-09-01 00:00:00

  • What is the significance of muciphages in colorectal biopsies? Muciphages and other mucosal accumulations in the colorectal mucosa.

    abstract::Muciphages (mucin-containing macrophages), first described in 1966 by Azzopardi & Evans, are a common feature of biopsies of large intestinal mucosa, even in the absence of other abnormalities such as active inflammation or evidence of chronic inflammatory bowel disease. Should they be mentioned in diagnostic reports?...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2000.0954b.x

    authors: Shepherd NA

    更新日期:2000-06-01 00:00:00

  • Current diagnostic strategies for undifferentiated tumours of the nasal cavities and paranasal sinuses.

    abstract::Several malignant tumours occurring in the sinonasal tract may present with an undifferentiated morphology. Overall, these lesions pose significant diagnostic difficulties for the surgical pathologist, especially in limited biopsy material, but their correct classification is becoming increasingly important for an app...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2559.2011.03813.x

    authors: Franchi A,Palomba A,Cardesa A

    更新日期:2011-12-01 00:00:00

  • Histological changes in the genital tract in transsexual women following androgen therapy.

    abstract::Thirty-two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1986.tb02520.x

    authors: Miller N,Bédard YC,Cooter NB,Shaul DL

    更新日期:1986-07-01 00:00:00

  • Differentiation of ovarian mucinous carcinoma and metastatic colorectal adenocarcinoma by immunostaining with beta-catenin.

    abstract:AIMS:To investigate whether localization of beta-catenin is helpful in differentiating primary ovarian mucinous carcinoma and colorectal adenocarcinoma metastatic to the ovary. Extra-ovarian cancers which metastasize to the ovaries, especially from colorectal adenocarcinoma, frequently mimic primary ovarian carcinomas,...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2003.01687.x

    authors: Chou YY,Jeng YM,Kao HL,Chen T,Mao TL,Lin MC

    更新日期:2003-08-01 00:00:00

  • Massive arterial haemorrhage from the lower gastrointestinal tract.

    abstract::We have studied the clinical, radiological and pathological features of three patients with recurrent massive lower gastrointestinal arterial haemorrhage. Case 1 was an example of Dieulafoy's vascular malformation within the proximal ascending colon in a 46-year-old woman. Cases 2 and 3 were men aged 81 and 83 years w...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1996.tb01395.x

    authors: Bateman AC,Beer TW,Bass PS,Odurny A,Gallagher PJ

    更新日期:1996-09-01 00:00:00

  • The extracellular matrix in pigmented skin lesions: an immunohistochemical study.

    abstract::In recent years the interaction between tumour cells and the surrounding extracellular matrix in the process of tumour development, invasion and metastasis has been a focus of interest. We studied frozen sections of nine naevocellular naevi (junctional, compound and intradermal), 40 dysplastic naevi, six pagetoid in s...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1994.tb01268.x

    authors: Van Duinen CM,Fleuren GJ,Bruijn JA

    更新日期:1994-01-01 00:00:00

  • Multidrug resistance-associated protein (MRP1) gene is strongly expressed in gastric carcinomas. Analysis by immunohistochemistry and real-time quantitative RT-PCR.

    abstract:AIMS:To assess MRP1 protein and MRP1 mRNA levels in gastric carcinomas and in non-neoplastic mucosa remote from the tumours. MRP1 gene expression may play a role in the complex pattern of chemoresistance present in gastric carcinomas. METHODS AND RESULTS:A total of 57 carcinomas and respective gastric tissues were inc...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2005.02100.x

    authors: Lacueva J,Perez-Ramos M,Soto JL,Oliver I,Andrada E,Medrano J,Perez-Vazquez T,Arroyo A,Carrato A,Ferragut JA,Calpena R

    更新日期:2005-04-01 00:00:00

  • Restrictive allograft syndrome and idiopathic pleuroparenchymal fibroelastosis: do they really have the same histology?

    abstract:AIMS:Restrictive allograft syndrome (RAS) and idiopathic pleuroparenchymal fibroelastosis (IPPFE) are two different diseases reported to share the same histology. RAS relates to chronic allograft dysfunction in lung transplantation, with IPPFE being a rare condition in native lungs. Our aim is to compare their histolog...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.13171

    authors: Montero MA,Osadolor T,Khiroya R,Salcedo MT,Robertus JL,Rice A,Nicholson AG,Roman A,Monforte V

    更新日期:2017-06-01 00:00:00

  • Pathological evaluation of the staging axillary lymph nodes for breast cancer: a national survey in the United Kingdom.

    abstract:AIMS:The handling and examination of sentinel lymph nodes (SLNs) to detect metastasis is critical in the assessment of early breast cancer patients. This survey investigates the variation in practise followed by pathology units across the United Kingdom in the staging evaluation of axillary lymph nodes (ALNs). METHODS...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12440

    authors: Verma R,Sundara Rajan S,Verghese ET,Horgan K,Hanby AM,Lane S

    更新日期:2014-11-01 00:00:00

  • Cutaneous heterotopic meningeal nodules.

    abstract::The clinical, light microscopic and immunohistochemical features of six cutaneous heterotopic meningeal nodules (primary, or type I, cutaneous meningiomas) are described. These are rare lesions of the scalp and back which generally present at birth or in childhood. They appear as small subcutaneous fibrous nodules, wi...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1990.tb01547.x

    authors: Theaker JM,Fletcher CD,Tudway AJ

    更新日期:1990-05-01 00:00:00

  • Hep Par 1 and selected antibodies in the immunohistological distinction of hepatocellular carcinoma from cholangiocarcinoma, combined tumours and metastatic carcinoma.

    abstract:AIMS:To examine the usefulness of Hep Par 1 together with selected antibodies in the separation of hepatocellular carcinoma (HCC) from cholangiocarcinoma (CC), combined tumours (HCC-CC) and metastatic carcinoma. METHODS AND RESULTS:Antibodies to Hep Par 1, CK19, CK20 and factor XIIIa were applied to 32 HCCs, 27 CCs, f...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.1998.00522.x

    authors: Leong AS,Sormunen RT,Tsui WM,Liew CT

    更新日期:1998-10-01 00:00:00

  • Low grade gastric B-cell lymphoma of mucosa associated lymphoid tissue in immunocompromised patients.

    abstract::An increased incidence of non-Hodgkin's lymphoma is seen in patients with immunodeficiency from any cause. The majority of these are high grade B-cell lymphoma and most are associated with the Epstein-Barr virus (EBV). In post-transplant lymphoma/lymphoproliferative disorders the tumour may regress following reduction...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.1996.292338.x

    authors: Wotherspoon AC,Diss TC,Pan L,Singh N,Whelan J,Isaacson PG

    更新日期:1996-02-01 00:00:00

  • Pulmonary adenocarcinoma with a micropapillary pattern: a clinicopathological, immunophenotypic and molecular analysis.

    abstract:AIMS:To investigate the clinicopathological and molecular characteristics, immunohistochemical profile and prognosis of pulmonary adenocarcinoma with a micropapillary pattern (MPPAC). METHODS AND RESULTS:Eight hundred and eighty-six pulmonary adenocarcinomas were divided into two groups: micropapillary pattern (MPP)-p...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2011.04050.x

    authors: Zhang J,Liang Z,Gao J,Luo Y,Liu T

    更新日期:2011-12-01 00:00:00

  • Diffuse large B-cell lymphoma showing an interfollicular pattern of proliferation: a study of the Osaka Lymphoma Study Group.

    abstract:AIMS:Diffuse large B-cell lymphoma (DLBCL) usually proliferates effacing lymph follicles. In occasional cases, tumour cells show an interfollicular pattern of proliferation preserving lymph follicles. The aim was to analyse clinicopathological findings in DLBCL showing an interfollicular pattern of proliferation to det...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2008.03018.x

    authors: Yamauchi A,Ikeda J,Nakamichi I,Kohara M,Fukuhara S,Hino M,Kanakura Y,Ogawa H,Sugiyama H,Kanamaru A,Aozasa K,Osaka Lymphoma Study Group.

    更新日期:2008-05-01 00:00:00

  • Primary leiomyosarcoma of bone.

    abstract::Four cases of primary leiomyosarcoma of bone are presented. The histology of this rare tumour has been studied with a panel of monoclonal antibodies to the intermediate filaments desmin and vimentin, and to other markers including smooth muscle actin, myosin, alpha 1-antitrypsin, alpha 1-antichymotrypsin, lysozyme, S-...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2559.1991.tb00031.x

    authors: Young MP,Freemont AJ

    更新日期:1991-09-01 00:00:00

  • Autofluorescent granular cells in odontogenic cysts.

    abstract::Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1984.tb02412.x

    authors: Browne RM,Rippin JW

    更新日期:1984-11-01 00:00:00

  • Immunohistochemical heterogeneity of macrophage subpopulations in human lymphoid tissues.

    abstract::The mononuclear phagocytic system is composed of cells which display a marked immunohistological heterogeneity. In the present study we have investigated the immunohistochemical and enzymatic features of macrophages and accessory cells present in human lymph nodes and spleen and, as control tissues, in thymus, liver, ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1987.tb01843.x

    authors: Baroni CD,Vitolo D,Remotti D,Biondi A,Pezzella F,Ruco LP,Uccini S

    更新日期:1987-10-01 00:00:00

  • Small cell carcinoma of urinary bladder is differentiated from urothelial carcinoma by chromogranin expression, absence of CD44 variant 6 expression, a unique pattern of cytokeratin expression, and more intense gamma-enolase expression.

    abstract:AIMS:Small cell (neuroendocrine) carcinoma of the urinary bladder is clinically more aggressive than urothelial (transitional cell) carcinoma. We have investigated the immunohistochemical markers most useful in diagnosing small cell carcinoma in bladder. METHODS AND RESULTS:We evaluated the expression of chromogranin ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.1999.00715.x

    authors: Iczkowski KA,Shanks JH,Allsbrook WC,Lopez-Beltran A,Pantazis CG,Collins TR,Wetherington RW,Bostwick DG

    更新日期:1999-08-01 00:00:00

  • Diversion colitis in children: an iatrogenic appendix vermiformis?

    abstract:AIMS:Diversion colitis (DC) is a localized, relatively benign, iatrogenic condition which occurs in almost 100% of diverted colonic segments in patients who undergo ileostomy/colostomy for various reasons. The aim of this study was to establish histological features of DC in children. METHODS AND RESULTS:Twenty-three ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2000.00803.x

    authors: Vujanić GM,Dojcinov SD

    更新日期:2000-01-01 00:00:00

  • Molecular pathology of bone tumours: diagnostic implications.

    abstract::Alongside histomorphology and immunohistochemistry, molecular pathology is now established as one of the cornerstones in the tissue diagnosis of bone tumours. We describe the principal molecular pathological techniques employed, and each of the bone tumour entities where their identified characteristic molecular patho...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/his.12275

    authors: Puls F,Niblett AJ,Mangham DC

    更新日期:2014-03-01 00:00:00

  • Blastic transformation of mantle cell lymphoma: genetic evidence for a clonal link between the two stages of the tumour.

    abstract:AIMS:The blastic variant of mantle cell lymphoma (MCL-BV) may develop through histological transformation of mantle cell lymphoma (MCL). However, the clonal link between the tumour cells of MCL and transformed MCL-BV has not been established at the genetic level. To investigate this link longitudinal molecular genetic ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.1999.00745.x

    authors: László T,Matolcsy A

    更新日期:1999-10-01 00:00:00

  • Expression of the extracellular matrix protein periostin in liver tumours and bile duct carcinomas.

    abstract:AIMS:To study the relevance of periostin, known to be involved in epithelial-mesenchymal transition (EMT), in hepatocellular and bile duct cancer. METHODS AND RESULTS:Immunohistochemical periostin expression was semiquantitatively analysed in normal liver tissue (n = 20), hepatocellular carcinoma (HCC; n = 91), liver-...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2010.03527.x

    authors: Riener MO,Fritzsche FR,Soll C,Pestalozzi BC,Probst-Hensch N,Clavien PA,Jochum W,Soltermann A,Moch H,Kristiansen G

    更新日期:2010-04-01 00:00:00

  • Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival.

    abstract:AIMS:To evaluate whether there is a correlation between the subcellular localization of maspin and the histological, molecular and biological features of pulmonary adenocarcinoma, particularly addressing the hypothesis that the tumour inhibitor properties of maspin may be linked to a nuclear, compared with a combined n...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2009.03260.x

    authors: Frey A,Soubani AO,Adam AK,Sheng S,Pass HI,Lonardo F

    更新日期:2009-04-01 00:00:00

  • Na+/H+ exchanger regulatory factor 1 expression levels in blood and tissue predict breast tumour clinical behaviour.

    abstract:AIMS:Several studies have demonstrated that Na(+) /H(+) exchanger regulatory factor 1 (NHERF1) protein, which is overexpressed and heterogeneously distributed in different stages of breast cancer, could be used as a tumour marker for prognosis in molecular detection strategies. We observed that tumour-infiltrated lymph...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2011.03844.x

    authors: Bellizzi A,Mangia A,Malfettone A,Cardone RA,Simone G,Reshkin SJ,Paradiso A

    更新日期:2011-06-01 00:00:00

  • Gene expression profile identifies a rare epithelioid variant case of pleomorphic liposarcoma carrying FUS-CHOP transcript.

    abstract:AIMS:To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic liposarcoma. Pleomorphic liposarcoma is a very rare variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts showing peculiar epithelial-like features that can be confu...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2005.02064.x

    authors: De Cecco L,Gariboldi M,Reid JF,Lagonigro MS,Tamborini E,Albertini V,Staurengo S,Pilotti S,Pierotti MA

    更新日期:2005-03-01 00:00:00

  • Specific histological abnormalities are more likely in biopsies of endoscopically normal large bowel after the age of 60 years.

    abstract:AIMS:Colonic and rectal biopsies, often taken from an endoscopically normal large bowel, form a significant proportion of the histopathology workload. The aim of this study was to determine diagnostic yield from mucosal biopsies in patients with normal colonoscopy or sigmoidoscopy, and whether or not diarrhoea is predi...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2012.04317.x

    authors: O'Mahony OH,Burgoyne M,Going JJ

    更新日期:2012-12-01 00:00:00

  • Mucin profiles in the mucosa adjacent to large bowel non-adenocarcinoma neoplasias.

    abstract::Morphological features and mucin secretion patterns were investigated in the colonic mucosa adjacent to or overlying mesenchymal or primary epithelial neoplasias, other than adenomas and adenocarcinomas. The material included 15 cases of non-adenocarcinoma tumours examined during 1978-1981. Increased sialomucins and m...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1984.tb02396.x

    authors: Lapertosa G,Fulcheri E,Acquarone M,Filipe MI

    更新日期:1984-09-01 00:00:00