Cutaneous heterotopic meningeal nodules.

abstract：:Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular pathology of thyroid tumours originating from follicular cells has greatly advanced in the past several years. Common molecular alterations, such as BRAF p.V600E, RAS point mutations, and fusion oncogenes (RET-PTC being the prototypical...

journal_title：Histopathology

authors： Acquaviva G,Visani M,Repaci A,Rhoden KJ,de Biase D,Pession A,Giovanni T

更新日期：2018-01-01 00:00:00

abstract：AIMS:Collagenous spherulosis (CS) is a rare lesion which is an incidental finding in breast and salivary glands. It is characterized by fibrillar spherules exhibiting an intrinsic radiating or concentric pattern which are surrounded by myoepithelial cells. This entity can be misdiagnosed as adenoid cystic carcinoma and...

journal_title：Histopathology

authors： Treilleux I,Godeneche J,Duvillard P,Clement-Chassagne C,Suignard Y,Bailly C

更新日期：1999-09-01 00:00:00

abstract：AIMS:The study was undertaken to demonstrate wild-type p53 in normal paraffin-embedded tissues using two widely used antibodies, DO7 and 1801 and two different antigen retrieval buffer systems. METHODS AND RESULTS:Formalin-fixed paraffin-embedded normal tissue samples were obtained from the archives of the John Radcli...

journal_title：Histopathology

authors： Pillai G,Roberts H,Gatter K,Pezzella F

更新日期：2003-01-01 00:00:00

abstract：AIMS:Tumour necrosis factor (TNF)-alpha induces death or cell proliferation by activation of nuclear factor (NF)-kappaB, also activated by interleukin (IL)-1 alpha. The aim was to investigate upstream and downstream components of NIK transduction pathway in normal (NP), benign prostatic hyperplasia (BPH), prostatic int...

journal_title：Histopathology

authors： Nuñez C,Cansino JR,Bethencourt F,Pérez-Utrilla M,Fraile B,Martínez-Onsurbe P,Olmedilla G,Paniagua R,Royuela M

更新日期：2008-08-01 00:00:00

abstract：AIMS:To establish the prevalence of CD44 protein expression in a large surgical series of Barrett's adenocarcinoma and associated preneoplastic lesions and to correlate this expression with clinicopathological data and prognosis. METHODS AND RESULTS:CD44H and variants (V4/V5, V6) expression was detected by immunohisto...

journal_title：Histopathology

authors： Lagorce-Pages C,Paraf F,Dubois S,Belghiti J,Fléjou JF

更新日期：1998-01-01 00:00:00

abstract：:Granular cell tumours rarely involve the lower respiratory tract. We report eight cases surgically resected at our institution. There were four females and four males, aged between 18 to 56 years (mean 40). One tumour associated with a peripheral lung adenocarcinoma was asymptomatic. The other lesions presented with o...

journal_title：Histopathology

authors： Thomas de Montpréville V,Dulmet EM

更新日期：1995-09-01 00:00:00

abstract：AIMS:We evaluated polymerase chain reaction (PCR) amplification of specific immunoglobulin heavy chain (IgH) gene rearrangements as a means of demonstrating monoclonality during follow-up of conservatively treated gastric MALT lymphoma, and compared the reproducibility of PCR on sequential frozen and paraffin-embedded ...

journal_title：Histopathology

authors： Aiello A,Giardini R,Tondini C,Balzarotti M,Diss T,Peng H,Delia D,Pilotti S

更新日期：1999-04-01 00:00:00

abstract：:Pulmonary typical carcinoid tumours are generally easy to diagnose with their uniform cells, carcinoid growth pattern and lack of mitoses. However, nuclear pleomorphism, which is common in other neuroendocrine tumours, is not emphasized in pulmonary carcinoid tumours. Three cases of typical carcinoid tumours, because ...

journal_title：Histopathology

authors： Sheppard MN

更新日期：1997-05-01 00:00:00

abstract：:Twenty-nine cases of non-Hodgkin's lymphoma of low-grade malignancy in a European population were investigated for the presence of bcl-2 and bcl-1 gene rearrangement. The cases were classified according to the Kiel classification. It was shown that bcl-2 gene rearrangements were exclusively confined to centroblastic-c...

journal_title：Histopathology

authors： Ott MM,Müller-Hermelink HK,Schmitt B,Feller AC

更新日期：1991-08-01 00:00:00

abstract：AIMS:Pathological or neuroprotective mechanisms in the brain in severe malaria may arise from microvascular obstruction with malaria-parasitized erythrocytes. This study aimed to investigate the role of hypoxia and induction of the vascular endothelial growth factor (VEGF) pathway in the neuropathophysiology of severe ...

journal_title：Histopathology

authors： Medana IM,Day NP,Roberts R,Sachanonta N,Turley H,Pongponratn E,Hien TT,White NJ,Turner GD

更新日期：2010-08-01 00:00:00

abstract：AIMS:Some experimental evidence suggests that in lung cancer, development, progression and an increased proliferation rate can be linked to apoptosis-related factors. In this study we evaluated the possible role of p53 and Bcl-2 gene family members as prognostic factors for non-small-cell lung cancer. METHODS AND RESU...

journal_title：Histopathology

authors： Groeger AM,Esposito V,De Luca A,Cassandro R,Tonini G,Ambrogi V,Baldi F,Goldfarb R,Mineo TC,Baldi A,Wolner E

更新日期：2004-01-01 00:00:00

abstract：AIMS:Programmed death ligand 1 (PD-L1) immunohistochemistry has become a mandatory diagnostic test in the treatment of lung cancer. Several research initiatives have started to harmonise the five PD-L1 immunohistochemistry assays that have been used in clinical trials. Here, we report data on interlaboratory and intera...

journal_title：Histopathology

authors： Scheel AH,Baenfer G,Baretton G,Dietel M,Diezko R,Henkel T,Heukamp LC,Jasani B,Jöhrens K,Kirchner T,Lasitschka F,Petersen I,Reu S,Schildhaus HU,Schirmacher P,Schwamborn K,Sommer U,Stoss O,Tiemann M,Warth A,Weichert

更新日期：2018-02-01 00:00:00

abstract：AIMS:The 2009 International Society of Urological Pathology consensus conference recommended reporting the extent of extraprostatic extension (EPE) for the prediction of outcome in prostate cancer. Our aim was to stratify EPE into prognostic groups. METHODS AND RESULTS:We reviewed 1051 radical prostatectomy (RP) speci...

journal_title：Histopathology

authors： Danneman D,Wiklund F,Wiklund NP,Egevad L

更新日期：2013-10-01 00:00:00

abstract：AIMS:p16, a tumour suppressor gene located at 9p21 chromosome and involved in cell cycle regulation, is often inactivated in lung carcinoma. Inactivation is also supported by the loss of p16 protein, a strong inhibitor of cyclin-dependent kinase (CDK) 4 and 6. The aim of this study was to examine alterations of p16 bot...

journal_title：Histopathology

authors： Dessy E,Rossi E,Berenzi A,Tironi A,Benetti A,Grigolato P

更新日期：2008-03-01 00:00:00

abstract：AIMS:The diagnosis of epithelioid haemangioendothelioma (EHE) is usually straightforward, based on characteristic histological features. However, it is sometimes difficult to differentiate EHE from a variety of other tumours with epithelioid morphology. The WW domain-containing transcription regulator 1-calmodulin-bind...

journal_title：Histopathology

authors： Shibuya R,Matsuyama A,Shiba E,Harada H,Yabuki K,Hisaoka M

更新日期：2015-12-01 00:00:00

abstract：AIMS:Atypical polypoid adenomyoma (APAM) is an uncommon uterine lesion composed of complex endometrioid glands with frequent squamous morular metaplasia and fibromuscular stroma. On endometrial curettage, biopsy, or polypectomy specimens, the admixture of endometrioid glands and smooth muscle raises the differential di...

journal_title：Histopathology

authors： Worrell HI,Sciallis AP,Skala SL

更新日期：2021-01-18 00:00:00

abstract：AIMS:Hepatocellular adenoma is an uncommon liver neoplasm and the studies of HCA subtypes have been primarily limited to France, United States and Japan. We aimed to describe the clinicopathologic features of hepatocellular adenoma subtypes in Turkey. METHODS AND RESULTS:The resection specimens of 59 cases diagnosed a...

journal_title：Histopathology

authors： Deniz K,Umetsu SE,Ferrell L,Yılmaz F,Güllüoğlu M,Sağol Ö,Bülbül Doğusoy G,Kırımlıoğlu H,Turhan N,Doran F,Kepil N,Çelikel ÇA,Nart D,Özgüven BY,Ceyran B,Karadağ N,Kır G,Erden E,Yılmaz G,Akyol G

更新日期：2021-01-06 00:00:00

abstract：AIMS:In skull base chordoma, c-MET expression has been reported to correlate with younger patient age and favourable prognosis; however, it also contributes to tumour invasiveness, especially in recurrent lesions, suggesting variable roles for c-MET according to clinical status. The aim of this study was to investigate...

journal_title：Histopathology

authors： Naka T,Boltze C,Samii A,Samii M,Herold C,Ostertag H,Iwamoto Y,Oda Y,Tsuneyoshi M,Kuester D,Roessner A

更新日期：2009-04-01 00:00:00

abstract：AIMS:Rare gastric lesions composed of a combined proliferation of chief and oxyntic cells have been variably called adenocarcinoma of fundic gland type and oxyntic gland polyp/adenoma. Herein, we present a series of cases that show a morphological spectrum of chief and oxyntic cell proliferations. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Chan K,Brown IS,Kyle T,Lauwers GY,Kumarasinghe MP

更新日期：2016-05-01 00:00:00

abstract：AIMS:To study relationships between the number of pseudomelanosis coli cells and that of colonic enteric neurons and interstitial cells of Cajal, which are significantly reduced compared with controls in severely constipated patients. Pseudomelanosis coli is frequent in patients using anthraquinone laxatives. It is not...

journal_title：Histopathology

authors： Villanacci V,Bassotti G,Cathomas G,Maurer CA,Di Fabio F,Fisogni S,Cadei M,Mazzocchi A,Salerni B

更新日期：2006-08-01 00:00:00

abstract：AIMS:Colorectal adenocarcinoma with enteroblastic differentiation (CAED) is a rare malignancy, and its clinicopathological characteristics have not yet been fully elucidated. This study aimed to elucidate the clinicopathological features of CAED through immunostaining of enteroblastic lineage markers alpha-fetoprotein ...

journal_title：Histopathology

authors： Murakami T,Yao T,Yatagai N,Yamashiro Y,Saito T,Sakamoto N,Nagahara A

更新日期：2020-01-01 00:00:00

abstract：:Two patients are described in each of whom metastatic prostatic carcinoma presented as a tumour of the parotid gland. In one, primary prostate cancer had been diagnosed three years prior to the appearance of what was believed clinically to be an unrelated salivary lesion. In the other a neck swelling was the first ind...

journal_title：Histopathology

authors： Simpson RH,Skálová A

更新日期：1997-01-01 00:00:00

abstract：:We have investigated the immunohistochemical expression of p53 protein in 96 cases of non-Hodgkin's lymphoma using a panel of five antibodies. Positive neoplastic cells were found in 30 (31.2%) cases, which could be divided into two groups according to their patterns of reactivity with the different antibodies; i.e. t...

journal_title：Histopathology

authors： Pezzella F,Morrison H,Jones M,Gatter KC,Lane D,Harris AL,Mason DY

更新日期：1993-01-01 00:00:00

abstract：:Adenomatous hyperplasia, defined as a sizable parenchymal nodule in cirrhosis, was examined morphologically. Ninety-seven nodules of adenomatous hyperplasia were obtained from 47 cirrhotic livers and were divided into 'ordinary' (44 nodules) and 'atypical' (53 nodules) types. The former consisted of hepatocytes simila...

journal_title：Histopathology

authors： Nakanuma Y,Terada T,Terasaki S,Ueda K,Nonomura A,Kawahara E,Matsui O

更新日期：1990-07-01 00:00:00

abstract：:Review of the histological sections of the tumours of 889 patients from the files of the SIOP Nephroblastoma trials and studies has revealed 23 cases with a distinctive growth pattern. Due to the similarity of the histological structures with the architecture of adenofibroma (fibroadenoma) of the ovary we have called ...

journal_title：Histopathology

authors： Delemarre JF,Sandstedt B,Tournade MF

更新日期：1984-01-01 00:00:00

abstract：:The monoclonal antibody NCRC-11, which has epithelial membrane antigen (EMA)-like immunoreactivity, was used to identify intracytoplasmic lumina in a series of 105 adenocarcinomas from various sites and in 283 breast carcinomas; 55% of the non-breast carcinomas and all breast carcinomas except one of spindle cell type...

journal_title：Histopathology

authors： Quincey C,Raitt N,Bell J,Ellis IO

更新日期：1991-07-01 00:00:00

abstract：AIMS:Macrophage colony-stimulating factor (M-CSF) binds to colony-stimulating factor-1 receptor (CSF-1R) and stimulates proliferation and differentiation of monocytes, macrophages and their bone marrow progenitors. M-CSF, CSF-1R, the macrophage marker CD68, and the pan T-lymphocyte marker CD3 are increased in many huma...

journal_title：Histopathology

authors： Richardsen E,Uglehus RD,Due J,Busch C,Busund LT

更新日期：2008-07-01 00:00:00

abstract：:One hundred and two cases of poorly differentiated adenocarcinoma were obtained from 71 surgical and 31 biopsy specimens of the stomach. These tumours produced both intracellular and extracellular mucins, which were demonstrated to be neutral mucins, N-acetyl sialomucins, sulphomucins and O-acetyl sialomucins. The maj...

journal_title：Histopathology

authors： Huang CB,Li WC,Xu J,Zhang YC

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:E-cadherin is a cell adhesion molecule that is expressed in normal breast tissue and is often considered useful as a phenotypic marker in breast cancer diagnosis, with absence of its expression frequently observed in tumours of lobular subtype. However, the clinicopathological and prognostic value of E-cadhe...

journal_title：Histopathology

authors： Rakha EA,Abd El Rehim D,Pinder SE,Lewis SA,Ellis IO

更新日期：2005-06-01 00:00:00

abstract：AIMS:Telepathology uses digitised image transfer to allow off-site reporting of histopathology slides. This technology could facilitate the centralisation of pathology services, which may improve their quality and cost-effectiveness. The benefits may be most apparent in frozen section reporting, in which turnaround tim...

journal_title：Histopathology

authors： French JMR,Betney DT,Abah U,Bhatt N,Internullo E,Casali G,Batchelor TJP,West DG

更新日期：2019-05-01 00:00:00