CAMTA1 is a useful immunohistochemical marker for diagnosing epithelioid haemangioendothelioma.

abstract：AIMS:We present three distinctive uterine tumours which exhibited immature smooth muscle differentiation mimicking smooth muscle cells of the fetal uterus. METHODS AND RESULTS:The patients were 45, 46 and 49 years old, and all of them had simple hysterectomies. Grossly, all tumours were present in the uterine body, an...

journal_title：Histopathology

authors： Watanabe K,Ogura G,Suzuki T

更新日期：2003-04-01 00:00:00

abstract：AIM:Special AT-rich sequence-binding protein 1 (SATB1) is a cell type-specific matrix attachment region binding protein, functioning as a global genome organizer. This study aims to investigate the expression pattern and the prognostic value of SATB1 in colorectal cancer. METHODS AND RESULTS:Prospectively collected da...

journal_title：Histopathology

authors： Al-Sohaily S,Henderson C,Selinger C,Pangon L,Segelov E,Kohonen-Corish MR,Warusavitarne J

更新日期：2014-08-01 00:00:00

abstract：AIMS:To investigate the immunohistochemical expression of KDR/flk-1 in a series of 114 urothelial bladder carcinomas in relation to clinicopathological parameters, Ki67, p53 and Bcl-2 protein expression and patient survival. KDR/flk-1 is a high-affinity tyrosine kinase receptor for vascular endothelial growth factor (V...

journal_title：Histopathology

authors： Gakiopoulou-Givalou H,Nakopoulou L,Panayotopoulou EG,Zervas A,Mavrommatis J,Giannopoulos A

更新日期：2003-09-01 00:00:00

abstract：:Six cases of polymorphous low-grade adenocarcinoma (terminal duct adenocarcinoma) of the minor salivary glands are presented. In all but one there was a history of a painless intra-oral mass of fairly long duration. The histopathological appearances were characterized by cytological uniformity in a variety of morpholo...

journal_title：Histopathology

authors： Simpson RH,Clarke TJ,Sarsfield PT,Gluckman PG,Babajews AV

更新日期：1991-08-01 00:00:00

abstract：:Biopsy and autopsy material from the urinary bladder was studied using PAS and PAS-D techniques to identify glycogen and neutral mucins, the alcian blue/high iron diamine method to distinguish sialo- and sulphamucins and the PB/KOH/PAS technique to localize O-acylated sialomucins. All of 10 examples of normal urotheli...

journal_title：Histopathology

authors： Newbould M,McWilliam LJ

更新日期：1990-09-01 00:00:00

abstract：:Increasingly more coherent data on the molecular characteristics of benign breast lesions and breast cancer precursors have led to the delineation of new multistep pathways of breast cancer progression through genotypic-phenotypic correlations. It has become apparent that oestrogen receptor (ER)-positive and -negative...

journal_title：Histopathology

authors： Lopez-Garcia MA,Geyer FC,Lacroix-Triki M,Marchió C,Reis-Filho JS

更新日期：2010-08-01 00:00:00

abstract：AIMS:Clear cell chondrosarcomas are known to occasionally contain areas of low-grade conventional chondrosarcoma; however, the opposite phenomenon has not yet been described. We identified five cases of conventional chondrosarcoma alongside clear cell chondrosarcoma. Here, we report on their clinicopathological and mol...

journal_title：Histopathology

authors： Lam SW,van Langevelde K,Suurmeijer AJH,Cleven AHG,Bovée JVMG

更新日期：2019-12-01 00:00:00

abstract：:Prostatic carcinoma (PCa) is a significant cause of cancer morbidity and mortality worldwide. Accurate staging is critical for prognosis assessment and treatment planning for PCa. Despite the large volume of clinical activity and research, the challenge to define the most appropriate and clinically relevant staging sy...

journal_title：Histopathology

authors： Cheng L,Montironi R,Bostwick DG,Lopez-Beltran A,Berney DM

更新日期：2012-01-01 00:00:00

abstract：AIMS:To investigate the expression and the prognostic role of glycoprotein Tenascin-C (Tn-C) in primary melanoma of the skin. METHODS AND RESULTS:The immunohistochemical expression of Tn-C was studied in 98 primary melanomas and related to inflammation, invasion, and patient outcome. Patients were followed up for dise...

journal_title：Histopathology

authors： Ilmonen S,Jahkola T,Turunen JP,Muhonen T,Asko-Seljavaara S

更新日期：2004-10-01 00:00:00

abstract：:Health care is a high-risk industry, with most documented adverse incidents being associated with 'human factors' including cognitive and social skills termed 'non-technical skills'. Non-technical skills complement the diagnostic and specialist skills and professional attributes required by medical practitioners, incl...

journal_title：Histopathology

authors： Johnston PW,Fioratou E,Flin R

更新日期：2011-09-01 00:00:00

abstract：:The use of drugs for recreational purposes is widespread. The drugs used can be divided into groups including stimulants (cocaine, amphetamines, etc.), opiates and opioids (heroin, oxycodone, methadone, fentanyl, etc.), sedatives (benzodiazepines and related substances) and miscellaneous drugs, including ketamine and ...

journal_title：Histopathology

authors： Milroy CM,Parai JL

更新日期：2011-10-01 00:00:00

abstract：:Clinicopathological and immunohistological features of three cases of large cell lymphoma of bone are reported. On histological grounds, all the cases were diagnosed as histiocytic lymphomas (Rappaport) or primary centroblastic lymphomas, polymorphic subtype (Kiel). On immunophenotyping, malignant cells strongly react...

journal_title：Histopathology

authors： Falini B,Binazzi R,Pileri S,Mori A,Bertoni F,Canino S,Fagioli M,Minelli O,Ciani C,Pellicioli P

更新日期：1988-02-01 00:00:00

abstract：AIMS:To clarify the lineage-specific carcinogenesis of gland-forming gastric neoplasms, by characterizing mucin phenotypes and proliferation patterns immunohistochemically using monoclonal antibodies against MUC2, MUC5AC, MUC6, CD10 and Ki67. METHODS AND RESULTS:We analysed 49 gland-forming intramucosal neoplasms, inc...

journal_title：Histopathology

authors： Nishimura R,Mukaisho K,Yamamoto H,Sonoda A,Andoh A,Fujiyama Y,Hattori T,Sugihara H

更新日期：2013-11-01 00:00:00

abstract：AIMS:Because of the clinical difficulty in identifying the early stages of human immunodeficiency virus (HIV) infection, the histopathologist often has to consider the diagnosis of HIV in tissue samples from patients with no previous suspicion of HIV infection. The aim was to investigate the practicality and utility of...

journal_title：Histopathology

authors： Moonim MT,Alarcon L,Freeman J,Mahadeva U,van der Walt JD,Lucas SB

更新日期：2010-03-01 00:00:00

abstract：AIMS:To look for FOXL2 mutation in rare ovarian epithelial lesions showing stromal components with morphological features of adult granulosa cell tumour (AGCT). METHODS AND RESULTS:We report the 402C→G FOXL2 mutation status in five epithelial ovarian lesions in women aged 45-77 years showing stromal proliferations tha...

journal_title：Histopathology

authors： Singh N,Gilks CB,Huntsman DG,Smith JH,Coutts M,Ganesan R,McCluggage WG

更新日期：2014-04-01 00:00:00

abstract：:The CD30 antigen is a characteristic phenotypic feature of Sternberg-Reed and Hodgkin cells and is also found in a subset of large cell non-Hodgkin's lymphomas. The finding of CD30 positive cells in some centroblastic/centrocytic (cb/cc) follicular lymphomas prompted us to characterize the presence and distribution of...

journal_title：Histopathology

authors： Piris M,Gatter KC,Mason DY

更新日期：1991-01-01 00:00:00

abstract：AIMS:The blastic variant of mantle cell lymphoma (MCL-BV) may develop through histological transformation of mantle cell lymphoma (MCL). However, the clonal link between the tumour cells of MCL and transformed MCL-BV has not been established at the genetic level. To investigate this link longitudinal molecular genetic ...

journal_title：Histopathology

authors： László T,Matolcsy A

更新日期：1999-10-01 00:00:00

abstract：AIMS:Despite increasing interest in the recently established immunoglobulin 4-related disease (IgG4-RD), its pathogenesis and aetiology remain largely unclear. Characteristic histopathological features are one of the key elements of diagnosis, including 'storiform' fibrosis, obliterative phlebitis, increased lymphoplas...

journal_title：Histopathology

authors： Nowak V,Agaimy A,Kristiansen G,Gütgemann I

更新日期：2020-01-01 00:00:00

abstract：:A study was made of the cells forming the crescents in human crescentic glomerulonephritis. The investigation was performed using a panel of antibodies with immunoperoxidase techniques in formalin fixed, paraffin embedded renal biopsy material. Some of the cells of glomerular crescents were found to contain cytokerati...

journal_title：Histopathology

authors： Harrison DJ,MacDonald MK

更新日期：1986-09-01 00:00:00

abstract：AIMS:Fibroadenomas (FAs) and phyllodes tumours (PTs) are fibroepithelial tumours. Mutations in MED12 exon 2 have been reported in FAs. This study investigated the MED12 mutations in a spectrum of fibroepithelial tumours. METHODS AND RESULTS:Using direct sequencing, we analysed MED12 exon 2 mutations on 121 samples, in...

journal_title：Histopathology

authors： Lien HC,Huang CS,Yang YW,Jeng YM

更新日期：2016-02-01 00:00:00

abstract：:The inflammatory infiltrate has been characterized in 10 cases of ovarian dysgerminoma using a panel of antisera to T-cells, B-cells and macrophages. The expression of Class II major histocompatibility complex (MHC) antigens and the distribution of interferons alpha and gamma were also examined. T-lymphocytes were pre...

journal_title：Histopathology

authors： Stewart CJ,Farquharson MA,Foulis AK

更新日期：1992-06-01 00:00:00

abstract：:The morphology, phenotype, genotype and clinical behaviour of four cases of mantle cell lymphoma (centrocytic lymphoma) presenting primarily in mucosa (two gastric, one in large bowel and one tonsillar) are reviewed. Their relationship with the broader group of mantle cell and mucosa-associated lymphoid tissue (MALT) ...

journal_title：Histopathology

authors： Fraga M,Lloret E,Sanchez-Verde L,Orradre JL,Campo E,Bosch F,Piris MA

更新日期：1995-05-01 00:00:00

abstract：:To identify histological preneoplastic lesions and early neoplastic foci, a histological and immunohistochemical study has been conducted on a series of 18 cases with the rare association of multiple intraductal papillomas and in situ breast carcinoma. The pathological and clinical data of these cases have been collat...

journal_title：Histopathology

authors： Papotti M,Gugliotta P,Ghiringhello B,Bussolati G

更新日期：1984-11-01 00:00:00

abstract：AIMS:Pulmonary chondromas, which are rare cartilaginous neoplasms that often arise in the setting of Carney triad, are morphologically similar to pulmonary hamartomas, which are much more common. There is evidence that succinate dehydrogenase (SDH) deficiency drives neoplasia in patients with Carney triad, and SDHB imm...

journal_title：Histopathology

authors： Chatzopoulos K,Fritchie KJ,Aubry MC,Carney JA,Folpe AL,Boland JM

更新日期：2019-12-01 00:00:00

abstract：AIM:Combined hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) (cHCC-CC) is a rare biphasic liver cancer. Recent studies have demonstrated that cHCC-CC originates from hepatic progenitor cells (HPCs). Spalt-like transcription factor 4 (SALL4) is a marker for a progenitor subclass of HCC with an aggressive phen...

journal_title：Histopathology

authors： Tanaka Y,Aishima S,Kohashi K,Okumura Y,Wang H,Hida T,Kotoh K,Shirabe K,Maehara Y,Takayanagi R,Oda Y

更新日期：2016-04-01 00:00:00

abstract：:Cancer biomarkers provide an opportunity to diagnose tumours earlier and with greater accuracy. They can also identify those patients most at risk of disease recurrence and predict which tumours will respond to different therapeutic approaches. Such biomarkers will be especially useful in the diagnosis and management ...

journal_title：Histopathology

authors： Proctor I,Stoeber K,Williams GH

更新日期：2010-07-01 00:00:00

abstract：:Some antigenic determinants can be preserved in tissues after plastic embedding. In the present study liver tissue was fixed with glutaraldehyde or paraformaldehyde, dehydrated with ethanol and toluene and embedded in araldite which was then polymerized at 37 degrees C. Immunofluorescence was performed on semi-thin se...

journal_title：Histopathology

authors： Scotto J

更新日期：1977-09-01 00:00:00

abstract：AIMS:bcl-2-associated transcription factor 1 (BCLAF1) is a nuclear protein that binds to bcl-related proteins and can induce apoptosis and autophagy. The aim of this study was to investigate the expression of BCLAF1 in a series of rectal cancers following neoadjuvant therapy. METHODS AND RESULTS:Immunohistochemistry w...

journal_title：Histopathology

authors： Brown GT,Cash B,Alnabulsi A,Samuel LM,Murray GI

更新日期：2016-03-01 00:00:00

abstract：:Problems in the interpretation and diagnosis of intraepithelial lesions of the uterine cervix include interobserver differences in respect of grading, uncertainty as to the significance of human papillomavirus infection and debate about the current terminology. The role of human papillomaviruses in cervical intra-epit...

journal_title：Histopathology

authors： Fox H,Buckley CH

更新日期：1990-07-01 00:00:00

abstract：:Aneuploidy is an important prognostic factor in many cancers. Chromosome 1 abnormalities are present in most breast carcinomas. These may be part of a non-specific increase in DNA (aneuploid status) or represent a restricted chromosomal abnormality. In 16 breast carcinomas we compared chromosome 1 aneusomy with ploidy...

journal_title：Histopathology

authors： Harrison MM,Magee HM,O'Loughlin JF,Gorey TF,Coyne JD,Dervan PA

更新日期：1997-03-01 00:00:00