Amyloidosis.

abstract：:The detailed documentation of ocular pathology has become an important component in the autopsy investigation of suspected cases of non-accidental injury in infants and young children. Careful histological examination of retinal haemorrhages is of critical importance, but there remains debate about the significance of...

journal_title：Histopathology

authors： Gilliland MG,Luthert P

更新日期：2003-12-01 00:00:00

abstract：AIMS:Y-box binding protein-1 (YB-1) is known to modulate gene transcription and protein translation, as well as cellular response to drug treatment. The aim of this study is to correlate YB-1 protein expression levels with clinicopathological parameters in intestinal-type gastric cancer tissue samples (as categorized b...

journal_title：Histopathology

authors： Guo T,Yu Y,Yip GW,Baeg GH,Thike AA,Lim TK,Tan PH,Matsumoto K,Bay BH

更新日期：2015-03-01 00:00:00

abstract：AIMS:Intraosseous jaw cysts with a solely orthokeratinized lining epithelium have been suggested to differ from the typical odontogenic keratocysts (OKC) by exhibiting a less aggressive behaviour. We report 15 cases of such cyst type under the term of 'orthokeratinized odontogenic cyst (OOC)' and compared their clinica...

journal_title：Histopathology

authors： Li TJ,Kitano M,Chen XM,Itoh T,Kawashima K,Sugihara K,Nozoe E,Mimura T

更新日期：1998-03-01 00:00:00

abstract：:In view of the critical role of dendritic cells in immune mediated skin diseases, we have investigated the membrane antigen patterns and ultrastructure of cutaneous dendritic cells in eight patients with chronic discoid lupus erythematosus and five with subacute cutaneous lupus erythematosus. In the lesional epidermis...

journal_title：Histopathology

authors： Mori M,Pimpinelli N,Romagnoli P,Bernacchi E,Fabbri P,Giannotti B

更新日期：1994-04-01 00:00:00

abstract：:In this study breast tissue that contained ultrastructural dense core granules has been examined from 24 patients. The possible neuroendocrine characteristics of the granules were studied using the uranaffin reaction and an ultrastructural argyrophil stain. The tissue included 15 breast carcinomas and nine benign samp...

journal_title：Histopathology

authors： Hopkinson HE,Battersby S,Anderson TJ

更新日期：1987-11-01 00:00:00

abstract：:One hundred and twenty-six radial scars and complex sclerosing lesions from 91 women were examined to determine the incidence of and the clinical and pathological factors associated with the development of carcinoma and atypical hyperplasia within them. There was a clear relationship between the presence of carcinoma ...

journal_title：Histopathology

authors： Sloane JP,Mayers MM

更新日期：1993-09-01 00:00:00

abstract：AIMS:To investigate platelet-derived growth factor receptor (PDGFR)alpha and PDGFRbeta expression and a mutational analysis of PDGFRalpha (exons 11, 12, 17 and 18) and PDGFRbeta (exon 12) genes in endometrial stromal sarcomas (ESS). Gastrointestinal stromal tumours (GISTs), which have somatic mutations of the transmemb...

journal_title：Histopathology

authors： Liegl B,Gülly C,Reich O,Nogales FF,Beham A,Regauer S

更新日期：2007-03-01 00:00:00

abstract：AIMS:Immune check-point inhibitors are known to cause immune-mediated adverse liver injury, but our knowledge is mainly based on cases treated with ipilimumab or nivolumab. METHODS AND RESULTS:Clinicopathological features of 10 patients with hepatobiliary adverse reactions caused by second-generation drugs, pembrolizu...

journal_title：Histopathology

authors： Zen Y,Chen YY,Jeng YM,Tsai HW,Yeh MM

更新日期：2020-02-01 00:00:00

abstract：:The International Collaboration on Cancer Reporting (ICCR) is a not-for-profit organisation sponsored by the Royal Colleges of Pathologists of Australasia and the United Kingdom, the College of American Pathologists, the Canadian Association of Pathologists in association with the Canadian Partnership Against Cancer, ...

journal_title：Histopathology

authors： Shanks JH,Srigley JR,Brimo F,Comperat E,Delahunt B,Koch M,Lopez-Beltran A,Reuter VE,Samaratunga H,Tsuzuki T,van der Kwast T,Varma M,Grignon D

更新日期：2019-10-01 00:00:00

abstract：:We report a case of oesophageal carcinosarcoma with prominent rhabdomyoblastic differentiation. Immunohistochemically, the rhabdomyblasts were mainly reactive to vimentin, cytokeratin, desmin, muscle-specific actin, myosin, and myoglobin, and were surrounded by laminin and type IV collagen-positive basement membranes....

journal_title：Histopathology

authors： Guarino M,Reale D,Micoli G,Forloni B

更新日期：1993-05-01 00:00:00

abstract：AIMS:The Notch signalling pathway is involved in normal development as well as tumorigenesis. However, it is unclear whether Notch activation is related to diverse clinicopathological factors in papillary thyroid carcinoma (PTC). METHODS AND RESULTS:We examined the relationship between clinicopathological factors and ...

journal_title：Histopathology

authors： Jung CW,Kong JS,Seol H,Park S,Koh JS,Lee SS,Kim MJ,Choi IJ,Myung JK

更新日期：2017-01-01 00:00:00

abstract：:The recognition of recurrent genetic alterations in specific tumour types has provided the basis for the reclassification of certain soft tissue neoplasms, and molecular analysis of patient material has the potential to provide both diagnostic and prognostic information. In this review, we evaluate the role of molecul...

journal_title：Histopathology

authors： Pfeifer JD,Hill DA,O'Sullivan MJ,Dehner LP

更新日期：2000-12-01 00:00:00

abstract：:Nine cases of Mullerian adenosarcoma of the uterine body, first defined in 1974 by Clement & Scully, are described. The tumour usually occurs in elderly women and appears macroscopically as a polypoid mass filling the uterine cavity. Histologically these neoplasms are characterized by having a benign epithelial compon...

journal_title：Histopathology

authors： Fox H,Harilal KR,Youell A

更新日期：1979-05-01 00:00:00

abstract：AIMS:Nitric oxide (NO), produced by inducible NO synthase (iNOS), has been suggested to cause oxidative stress, leading to 8-hydroxydeoxyguanosine (8-OHdG) accumulation and subsequent transversion mutation of DNA. The aim was to evaluate iNOS expression and the status of oxidative stress in nasopharyngeal carcinoma (NP...

journal_title：Histopathology

authors： Segawa Y,Oda Y,Yamamoto H,Uryu H,Shiratsuchi H,Hirakawa N,Tomita K,Yamamoto T,Oda S,Yamada T,Komune S,Tsuneyoshi M

更新日期：2008-01-01 00:00:00

abstract：AIMS:To assess the immunophenotypic changes associated with epithelial-mesenchymal transition (EMT) in endocervical adenocarcinoma, and correlate the findings with tumour morphology including growth pattern. METHODS AND RESULTS:Twenty-seven endocervical adenocarcinomas were studied using a panel of immunohistochemical...

journal_title：Histopathology

authors： Stewart CJ,Crook ML,Little L,Louwen K

更新日期：2011-04-01 00:00:00

abstract：AIMS:To evaluate whether there is a correlation between the subcellular localization of maspin and the histological, molecular and biological features of pulmonary adenocarcinoma, particularly addressing the hypothesis that the tumour inhibitor properties of maspin may be linked to a nuclear, compared with a combined n...

journal_title：Histopathology

authors： Frey A,Soubani AO,Adam AK,Sheng S,Pass HI,Lonardo F

更新日期：2009-04-01 00:00:00

abstract：AIMS:Tissue microarray (TMA) is an efficient technique for analysis of molecular markers. Prospectively collected samples have been reported to give excellent concordance between TMA data and corresponding whole-sections. The aim was to evaluate the usefulness of TMA in a population-based cohort of 213 women with ducta...

journal_title：Histopathology

authors： Wärnberg F,Amini RM,Goldman M,Jirström K

更新日期：2008-12-01 00:00:00

abstract：AIMS:Malignant odontogenic tumours (MOTs) are rare neoplasms occurring primarily within the jaw. The objective of this study was to determine the incidence, demographics and clinicopathological features of the MOTs from two institutions. METHODS AND RESULTS:The records of the Department of Oral Pathology, Faculty of D...

journal_title：Histopathology

authors： Chaisuparat R,Sawangarun W,Scheper MA

更新日期：2012-07-01 00:00:00

abstract：:Chronic inflammatory cells are a recognized component of atherosclerotic plaques at all stages of development. As adhesion molecules play a fundamental role in inflammatory processes, we have carried out an immunohistochemical investigation of the distribution of endothelial leucocyte adhesion molecule-1 (ELAM-1)*, in...

journal_title：Histopathology

authors： Wood KM,Cadogan MD,Ramshaw AL,Parums DV

更新日期：1993-05-01 00:00:00

abstract：AIMS:To evaluate the relationship between phenotypic expression and tumour progression as represented by macroscopic features, submucosal invasion and lymph node metastasis in early differentiated gastric adenocarcinoma. METHODS:One hundred and fifty-five cases of early gastric differentiated adenocarcinoma without an...

journal_title：Histopathology

authors： Nakamura T,Yao T,Kabashima A,Nishiyama K,Maehara Y,Tsuneyoshi M

更新日期：2005-10-01 00:00:00

abstract：AIMS:Cyclin D1 overexpression was examined in early gastric carcinomas and precursor lesions with the following aims; (1) to assess the chronology of cyclin D1 overexpression in various stages of gastric carcinogenesis, (2) to correlate cyclin D1 overexpression with the Lauren type, the grade of differentiation and the...

journal_title：Histopathology

authors： Blok P,Craanen ME,van Diest PJ,Dekker W,Tytgat GN

更新日期：2000-02-01 00:00:00

abstract：:Many classification schemes have been proposed for ductal carcinoma in situ. Architectural heterogeneity is widely recognized. Cytonuclear grade appears to have greater prognostic significance than architectural pattern. This study assesses heterogeneity using a classification based on cytological grade and compares t...

journal_title：Histopathology

authors： Harrison M,Coyne JD,Gorey T,Dervan PA

更新日期：1996-05-01 00:00:00

abstract：AIMS:Perineural invasion (PNI) by prostatic adenocarcinoma is debated as a prognostic parameter. This study investigates the prognostic predictive value of PNI in a series of patients with locally advanced prostate cancer treated with radiotherapy and androgen deprivation using 10 years outcome data from the TROG 03.04...

journal_title：Histopathology

authors： Delahunt B,Murray JD,Steigler A,Atkinson C,Christie D,Duchesne G,Egevad L,Joseph D,Matthews J,Oldmeadow C,Samaratunga H,Spry NA,Srigley JR,Hondermarck H,Denham JW

更新日期：2020-08-01 00:00:00

abstract：:Prolongation of ovarian epithelial cancer survival depends on early detection or improved responses to chemotherapy. Gains in either have been modest at best. Understanding the diverse pathogenesis of this disease is critical to early intervention or prevention. This review addresses six important variables, including...

journal_title：Histopathology

authors： Jarboe EA,Folkins AK,Drapkin R,Ince TA,Agoston ES,Crum CP

更新日期：2008-08-01 00:00:00

abstract：:The benign 'Triton' tumour is a neural tumour with benign rhabdomyomatous differentiation: it must be distinguished from the better known malignant counterpart. We describe the first case outside the peripheral soft tissues and the first to be studied ultrastructurally. It also represents the second lesion identified ...

journal_title：Histopathology

authors： Azzopardi JG,Eusebi V,Tison V,Betts CM

更新日期：1983-07-01 00:00:00

abstract：AIMS:The clinical significance of common histological parameters in acute interstitial nephritis (AIN) is uncertain. We aimed to evaluate the utility of histology in predicting clinical outcomes in patients with AIN. METHODS AND RESULTS:Adult renal biopsies yielding a diagnosis of AIN between 2000 and 2015 were re-exa...

journal_title：Histopathology

authors： Rankin AJ,Cannon E,Gillis K,Crosby J,Mark PB,Geddes CC,Fox JG,Mackinnon B,McQuarrie EP,Kipgen D

更新日期：2020-04-01 00:00:00

abstract：AIMS:Pulmonary chondromas, which are rare cartilaginous neoplasms that often arise in the setting of Carney triad, are morphologically similar to pulmonary hamartomas, which are much more common. There is evidence that succinate dehydrogenase (SDH) deficiency drives neoplasia in patients with Carney triad, and SDHB imm...

journal_title：Histopathology

authors： Chatzopoulos K,Fritchie KJ,Aubry MC,Carney JA,Folpe AL,Boland JM

更新日期：2019-12-01 00:00:00

abstract：AIMS:Angiogenesis is an important factor in tumour growth and metastasis. Vascular endothelial growth factor receptor 2 (VEGFR-2) or KDR plays a crucial role in angiogenesis. The aim of this study was to raise and characterize antibodies against phosphorylated KDR which could be used for studies on human tissues to ass...

journal_title：Histopathology

authors： Stewart M,Turley H,Cook N,Pezzella F,Pillai G,Ogilvie D,Cartlidge S,Paterson D,Copley C,Kendrew J,Barnes C,Harris AL,Gatter KC

更新日期：2003-07-01 00:00:00

abstract：:Gonadoblastoma is defined as a neoplasm containing nests of germ cells and cells resembling Sertoli cells or granulosa cells. Gonadoblastomas arise almost exclusively in dysgenetic gonads. They are associated with an increased risk of developing germ cell tumours. Testicular germ cell tumours in adults are preceded by...

journal_title：Histopathology

authors： Jørgensen N,Müller J,Jaubert F,Clausen OP,Skakkebaek NE

更新日期：1997-02-01 00:00:00

abstract：:The use of drugs for recreational purposes is widespread. The drugs used can be divided into groups including stimulants (cocaine, amphetamines, etc.), opiates and opioids (heroin, oxycodone, methadone, fentanyl, etc.), sedatives (benzodiazepines and related substances) and miscellaneous drugs, including ketamine and ...

journal_title：Histopathology

authors： Milroy CM,Parai JL

更新日期：2011-10-01 00:00:00