Abstract:
AIMS:Intraosseous jaw cysts with a solely orthokeratinized lining epithelium have been suggested to differ from the typical odontogenic keratocysts (OKC) by exhibiting a less aggressive behaviour. We report 15 cases of such cyst type under the term of 'orthokeratinized odontogenic cyst (OOC)' and compared their clinical, histological and immunocytochemical features with that of OKC. METHODS AND RESULTS:The cysts of the present series were all solitary lesions, occurred mostly in young male patients, and showed a predilection for the posterior mandible areas. Follow-up of 14 patients, nine of whom were treated by simple enucleation, revealed no recurrence over a period of 3.5-12 years after surgery. None of the patients had any association with the naevoid basal cell carcinoma syndrome. Furthermore, histological and immunocytochemical comparison between OOC and OKC revealed marked differences in their morphology and epithelial expression. The lining epithelium of OOC lacked the typical features of OKC and appeared to show a lower proliferative activity. CONCLUSION:These findings suggest that OOC is clinicopathologically separate from other types of odontogenic cysts and may thus constitute a distinct clinical entity.
journal_name
Histopathologyjournal_title
Histopathologyauthors
Li TJ,Kitano M,Chen XM,Itoh T,Kawashima K,Sugihara K,Nozoe E,Mimura Tdoi
10.1046/j.1365-2559.1998.00380.xsubject
Has Abstractpub_date
1998-03-01 00:00:00pages
242-51issue
3eissn
0309-0167issn
1365-2559journal_volume
32pub_type
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