Recent advances in intestinal lymphomas.

Abstract:

:A large variety of lymphoma types may develop as primary intestinal neoplasms in the small intestines or, less often, in the colorectum. Among these are a few entities such as enteropathy-associated T-cell lymphoma or immunoproliferative small intestinal disease that, essentially, do not arise elsewhere than in the gastrointestinal tract. In most instances the primary intestinal lymphomas belong to entities that also occur in lymph nodes or other mucosal sites, and may show some peculiar features. In the case of follicular lymphoma, important differences exist between the classical nodal cases and the intestinal cases, considered as a variant of the disease. It is likely that the local intestinal mucosal microenvironment is a determinant in influencing the pathobiological features of the disease. In this review we will present an update on the clinical, pathological and molecular features of the lymphoid neoplasms that most commonly involve the intestines, incorporating recent developments with respect to their pathobiology and classification. We will emphasize and discuss the major differential diagnostic problems encountered in practice, including the benign reactive or atypical lymphoid hyperplasias, indolent lymphoproliferative disorders of T or natural killer (NK) cells, and Epstein-Barr virus (EBV)-related lymphoproliferations.

journal_name

Histopathology

journal_title

Histopathology

authors

Foukas PG,de Leval L

doi

10.1111/his.12596

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

112-36

issue

1

eissn

0309-0167

issn

1365-2559

journal_volume

66

pub_type

杂志文章,评审
  • Oxidative stress markers and mitochondrial antioxidant enzyme expression are increased in aggressive Hodgkin lymphomas.

    abstract:AIMS:Hodgkin lymphoma treatments are largely based on the generation of reactive oxygen species, but increased expression of antioxidant enzymes may contribute to chemoresistance. The aims of this study were: to define the extent and prognostic value of oxidative stress marker and antioxidant enzyme expression in Hodgk...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12389

    authors: Bur H,Haapasaari KM,Turpeenniemi-Hujanen T,Kuittinen O,Auvinen P,Marin K,Koivunen P,Sormunen R,Soini Y,Karihtala P

    更新日期:2014-09-01 00:00:00

  • Role of Fos-related antigen 1 in the progression and prognosis of ductal breast carcinoma.

    abstract:AIMS:Fos-related antigen 1 (Fra-1) is a member of the activator protein 1 (AP-1) transcription factor family. Our objective was to evaluate the role of Fra-1 expression in breast carcinoma progression and prognosis. METHODS AND RESULTS:Fra-1 expression was investigated by immunohistochemistry in two tissue microarrays...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2011.03785.x

    authors: Logullo AF,Stiepcich MM,Osório CA,Nonogaki S,Pasini FS,Rocha RM,Soares FA,Brentani MM

    更新日期:2011-03-01 00:00:00

  • Histological indicators of prognosis in glioblastomas: retinoblastoma protein expression and oligodendroglial differentiation indicate improved survival.

    abstract:AIM:To assess the potential prognostic significance of a range of molecular and morphological parameters in glioblastomas that can be applied in the setting of a routine diagnostic neuropathology laboratory. METHODS AND RESULTS:A consecutive series of 107 adult glioblastomas were studied. Retinoblastoma and deleted-in...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2004.01887.x

    authors: Hilton DA,Penney M,Pobereskin L,Sanders H,Love S

    更新日期:2004-06-01 00:00:00

  • Bile duct basement membrane thickening in primary sclerosing cholangitis.

    abstract:AIMS:Primary sclerosing cholangitis (PSC) is characterized histologically by portal inflammation, bile duct injury and regeneration and concentric periductal fibrosis. Although seen commonly in our experience, the significance of histological thickening of the bile duct basement membrane on periodic acid Schiff (PAS)-p...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12857

    authors: Colling R,Verrill C,Fryer E,Kartsonaki C,Wang LM,Chapman R,Rajabally N,Fleming K

    更新日期:2016-05-01 00:00:00

  • Spinal melanotic schwannoma: a tumour with poor prognosis.

    abstract:AIM:To clarify the prognosis of melanotic schwannoma. This is a rare tumour which is generally considered as a benign lesion, reported in many cases with a short follow-up only. METHODS AND RESULTS:Five cases of spinal melanotic schwannoma were retrospectively studied. The tumours were examined using standard histolog...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.1999.00786.x

    authors: Vallat-Decouvelaere AV,Wassef M,Lot G,Catala M,Moussalam M,Caruel N,Mikol J

    更新日期:1999-12-01 00:00:00

  • Immunohistochemical demonstration of p24 HTLV III major core protein in different cell types within lymph nodes from patients with lymphadenopathy syndrome (LAS).

    abstract::The p24 protein is the major core protein of LAV/HTLV III which is the putative agent of the lymphadenopathy syndrome. By the use of an anti-p24 monoclonal antibody we have studied the presence of LAV/HTLV III infected cells in 20 lymph nodes obtained from lymphadenopathy syndrome patients: 14 lymph nodes were charact...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1986.tb02456.x

    authors: Baroni CD,Pezzella F,Mirolo M,Ruco LP,Rossi GB

    更新日期:1986-01-01 00:00:00

  • Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival.

    abstract:AIMS:To evaluate whether there is a correlation between the subcellular localization of maspin and the histological, molecular and biological features of pulmonary adenocarcinoma, particularly addressing the hypothesis that the tumour inhibitor properties of maspin may be linked to a nuclear, compared with a combined n...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2009.03260.x

    authors: Frey A,Soubani AO,Adam AK,Sheng S,Pass HI,Lonardo F

    更新日期:2009-04-01 00:00:00

  • Immunocytochemical study of 12E7 in small round-cell tumours of childhood: an assessment of its sensitivity and specificity.

    abstract::12E7 is a monoclonal antibody to the MIC2 gene product and can be applied to formalin-fixed, paraffin-embedded tissue. The diagnostic utility of 12E7 as a marker of Ewing's sarcoma and peripheral neuroectodermal tumour was assessed. Immunocytochemical studies were performed on 120 small round-cell tumours from childre...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1993.tb01243.x

    authors: Ramani P,Rampling D,Link M

    更新日期:1993-12-01 00:00:00

  • MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics.

    abstract:AIMS:Secretory carcinoma (SC) (synonym: mammary analogue secretory carcinoma) is a low-grade salivary gland tumour that occurs in both major and minor salivary glands. SC is known for its wide morphological, architectural and immunohistochemical spectrum, which overlaps with those of several salivary gland neoplasms, i...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.14251

    authors: Taverna C,Baněčková M,Lorenzon M,Palomba A,Franchi A,Skalova A,Agaimy A

    更新日期:2020-09-15 00:00:00

  • Two distinct pathways of carcinogenesis in primary sclerosing cholangitis.

    abstract:AIMS:To identify clinicopathological characteristics of cholangiocarcinoma and premalignant lesions arising in patients with primary sclerosing cholangitis (PSC). METHODS AND RESULTS:This study consisted of 25 patients with PSC and bile duct neoplasia [16 with cholangiocarcinoma and nine with biliary intra-epithelial ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2011.04048.x

    authors: Zen Y,Quaglia A,Heaton N,Rela M,Portmann B

    更新日期:2011-12-01 00:00:00

  • Cerebral ganglioglioma with anaplastic oligodendroglial component.

    abstract::We report an unusual and possibly unique example of cerebral ganglioglioma with an anaplastic oligodendroglial component. The latter was documented on both morphological and immunohistochemical grounds. Immunohistochemically, the anaplastic cells were strongly positive with the monoclonal antibody anti-Leu-7, while th...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1990.tb00765.x

    authors: Allegranza A,Pileri S,Frank G,Ferracini R

    更新日期:1990-11-01 00:00:00

  • Pigmented spindle cell carcinoid tumour of the thymus with ectopic adrenocorticotropic hormone secretion: report of a rare variant and differential diagnosis of mediastinal spindle cell neoplasms.

    abstract:AIMS:A variety of histological variants of thymic carcinoid tumour have been described. A rare case of pigmented spindle cell carcinoid tumour of the thymus is documented and compared with the reported cases of thymic pigmented carcinoid tumour in the literature, with a discussion of the differential diagnosis of spind...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2559.2002.01339.x

    authors: Kuo TT

    更新日期:2002-02-01 00:00:00

  • Diagnostic utility of BAP1 and EZH2 expression in malignant mesothelioma.

    abstract:AIMS:Malignant mesothelioma is a highly aggressive cancer that is usually diagnosed at advanced stages; thus, highly sensitive and specific markers are necessary for its early definitive diagnosis. The aim of this study was to evaluate the diagnostic utility and prognostic significance of BAP1 and EZH2 in malignant mes...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.13123

    authors: Shinozaki-Ushiku A,Ushiku T,Morita S,Anraku M,Nakajima J,Fukayama M

    更新日期:2017-04-01 00:00:00

  • Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes.

    abstract:AIMS:Colorectal cancers deficient in DNA mismatch repair (MMR) are often characterized by the presence of numerous intraepithelial lymphocytes (IELs). These CD8+ T cells selectively express CD103, which is upregulated locally by transforming growth factor (TGF)-beta, and adhere to E-cadherin expressed by mucosal epithe...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2006.02520.x

    authors: Baker K,Chong G,Foulkes WD,Jass JR

    更新日期:2006-10-01 00:00:00

  • Pathological prognostic factors in locally advanced rectal carcinoma after neoadjuvant radiochemotherapy: analysis of 113 cases.

    abstract:AIMS:Neoadjuvant radiochemotherapy (RCT) followed by surgical resection is the treatment for locally advanced mid-rectal or low rectal cancer. The aim of this study was to evaluate postoperative histological prognostic factors in a series of surgical specimens after neoadjuvant RCT. METHODS AND RESULTS:One hundred and...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12432

    authors: Sannier A,Lefèvre JH,Panis Y,Cazals-Hatem D,Bedossa P,Guedj N

    更新日期:2014-11-01 00:00:00

  • Clinicopathological significance of EGFR pathway gene mutations and CRTC1/3-MAML2 fusions in salivary gland mucoepidermoid carcinoma.

    abstract:AIMS:Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland carcinomas. Epidermal growth factor receptor (EGFR) signalling pathway gene mutations are important in predicting a patient's prognosis, selecting molecularly targeted drugs and estimating the efficacy of a molecular therapy. However, their si...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.14100

    authors: Morita M,Murase T,Okumura Y,Ueda K,Sakamoto Y,Masaki A,Kawakita D,Tada Y,Nibu KI,Shibuya Y,Inagaki H

    更新日期:2020-06-01 00:00:00

  • An immunohistological study of granulomatous prostatitis.

    abstract::Granulomatous prostatitis may result from tuberculosis and fungal infection and has been described following prostatic surgery. In most cases, however, the aetiology is unknown, although it may be due to a reaction to extravasated or altered prostatic secretions. We have investigated cells (macrophages, lymphocytes), ...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1991.tb00874.x

    authors: Dhundee J,Maciver AG

    更新日期:1991-05-01 00:00:00

  • Gleason drift in the NIHR ProtecT study.

    abstract:AIMS:There is increasing evidence of Gleason score (GS) drift in prostatic core biopsies during the last two decades. The ProtecT study is a randomized controlled study and provides an excellent cohort to study the effect of time, prostate-specific antigen (PSA) level, perineural invasion, tumour length and age on GS. ...

    journal_title:Histopathology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/his.12549

    authors: Oxley J,Simpkin A,Goepel J,Varma M,Griffiths D,Grigor K,Mayer N,Warren A,Deshmukh N,Bhattarai S,Dormer J,Hounsome L,Adamczyk LA,Metcalfe C,Lane JA,Davis M,Donovan JL,Neal DE,Hamdy FC,Robinson MC,ProtecT Study Grou

    更新日期:2015-02-01 00:00:00

  • DNA content in gallbladder carcinoma: a flow cytometric study of 96 cases.

    abstract::The DNA content in gallbladder carcinoma and its relation to histological and cytological features was studied in 79 primary gallbladder carcinomas and 16 metastases. Abnormal DNA content was observed in 48 (51%) of 95 cases. In primary carcinomas, 44 (55.6%) showed a diploid DNA content, and 35 (44.4%) were aneuploid...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1993.tb00495.x

    authors: Roa I,Araya JC,Shiraishi T,Yatani R,Wistuba I,Villaseca M,De Aretxabala X

    更新日期:1993-11-01 00:00:00

  • Dirofilariasis due to Dirofilaria repens in Italy, an emergent zoonosis: report of 60 new cases.

    abstract:AIMS:Sixty new cases of human dirofilariasis due to Dirofilaria repens, occurring in Italy between 1990 and 1999, are presented. This is the most extensive case study of this zoonosis reported worldwide by a single study group. The aim is to utilize this large experience to characterize the different histopathological ...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2559.2001.01099.x

    authors: Pampiglione S,Rivasi F,Angeli G,Boldorini R,Incensati RM,Pastormerlo M,Pavesi M,Ramponi A

    更新日期:2001-04-01 00:00:00

  • Immunohistochemical characterization of prototypical endometrial clear cell carcinoma--diagnostic utility of HNF-1β and oestrogen receptor.

    abstract:AIMS:The great majority of ovarian clear cell carcinomas have a hepatocyte nuclear factor 1 homeobox B (HNF-1β)-positive and oestrogen receptor (ER)-negative immunoprofile. However, the pattern of HNF-1β and ER immunostaining in clear cell carcinomas of the endometrium and the usefulness of this panel in distinguishing...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12286

    authors: Hoang LN,Han G,McConechy M,Lau S,Chow C,Gilks CB,Huntsman DG,Köbel M,Lee CH

    更新日期:2014-03-01 00:00:00

  • Neuroendocrine cells in cystic mucinous tumours of the ovary.

    abstract::This histogenesis of cystic mucinous ovarian tumours is still controversial. It has been proposed that these neoplasms may arise from metaplastic ovarian surface epithelium. Others have suggested that these tumours represent monophyletic (intestinal) types of teratoma. Against this background we have studied the prese...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1983.tb02252.x

    authors: Louwerens JK,Schaberg A,Bosman FT

    更新日期:1983-05-01 00:00:00

  • TFE3 translocation and protein expression in renal cell carcinoma are correlated with poor prognosis.

    abstract:AIMS:Since Xp11.2 translocation-associated renal cell carcinoma (TRCC) was first recognised, its morphological features and the clinical significance of TFE3 expression, frequency of gene translocation and diagnostic criteria have been the subject of limited studies. The present retrospective analysis aimed to evaluate...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.13700

    authors: Lee HJ,Shin DH,Kim SY,Hwang CS,Lee JH,Park WY,Choi KU,Kim JY,Lee CH,Sol MY,Rha SH,Park SW

    更新日期:2018-11-01 00:00:00

  • Comparative study of soft tissue perineurioma and meningioma using a five-marker immunohistochemical panel.

    abstract:AIMS:Owing to their close embryological relationship, soft tissue perineurioma and meningioma may closely mimic each other, not only histologically but also by immunohistochemistry. We aimed to compare the frequency of perineurial marker expression in these two entities, and to determine whether somatostatin receptor 2...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.12366

    authors: Agaimy A,Buslei R,Coras R,Rubin BP,Mentzel T

    更新日期:2014-07-01 00:00:00

  • Hepatocellular adenomas in the turkish population: reclassification using updated world health organization criteria.

    abstract:AIMS:Hepatocellular adenoma is an uncommon liver neoplasm and the studies of HCA subtypes have been primarily limited to France, United States and Japan. We aimed to describe the clinicopathologic features of hepatocellular adenoma subtypes in Turkey. METHODS AND RESULTS:The resection specimens of 59 cases diagnosed a...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/his.14330

    authors: Deniz K,Umetsu SE,Ferrell L,Yılmaz F,Güllüoğlu M,Sağol Ö,Bülbül Doğusoy G,Kırımlıoğlu H,Turhan N,Doran F,Kepil N,Çelikel ÇA,Nart D,Özgüven BY,Ceyran B,Karadağ N,Kır G,Erden E,Yılmaz G,Akyol G

    更新日期:2021-01-06 00:00:00

  • Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective.

    abstract::Prolongation of ovarian epithelial cancer survival depends on early detection or improved responses to chemotherapy. Gains in either have been modest at best. Understanding the diverse pathogenesis of this disease is critical to early intervention or prevention. This review addresses six important variables, including...

    journal_title:Histopathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2559.2007.02938.x

    authors: Jarboe EA,Folkins AK,Drapkin R,Ince TA,Agoston ES,Crum CP

    更新日期:2008-08-01 00:00:00

  • Inappropriate mucin production in gall bladder metaplasia and neoplasia--an immunohistological study.

    abstract::This study demonstrates the presence of three antigens in glandular metaplasia occurring in patients with cholecystitis and cholelithiasis: specifically carcinoembryonic antigen (CEA), large intestinal mucin antigen (LIMA) and small intestinal mucin antigen (SIMA). These antigens could not be detected in normal gall b...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.1981.tb01788.x

    authors: De Boer WG,Ma J,Rees JW,Nayman J

    更新日期:1981-05-01 00:00:00

  • TNF/IL-1/NIK/NF-kappa B transduction pathway: a comparative study in normal and pathological human prostate (benign hyperplasia and carcinoma).

    abstract:AIMS:Tumour necrosis factor (TNF)-alpha induces death or cell proliferation by activation of nuclear factor (NF)-kappaB, also activated by interleukin (IL)-1 alpha. The aim was to investigate upstream and downstream components of NIK transduction pathway in normal (NP), benign prostatic hyperplasia (BPH), prostatic int...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2008.03092.x

    authors: Nuñez C,Cansino JR,Bethencourt F,Pérez-Utrilla M,Fraile B,Martínez-Onsurbe P,Olmedilla G,Paniagua R,Royuela M

    更新日期:2008-08-01 00:00:00

  • Cytoplasmic expression of survivin is an independent predictor of poor prognosis in patients with salivary gland cancer.

    abstract:AIMS:The expression of the inhibitor of apoptosis protein survivin has been shown to be a significant prognostic indicator in various human cancers. The aim was to assess its expression and prognostic value in salivary gland adenocarcinoma and muco-epidermoid carcinoma. METHODS AND RESULTS:Survivin expression was anal...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2010.03693.x

    authors: Stenner M,Weinell A,Ponert T,Hardt A,Hahn M,Preuss SF,Guntinas-Lichius O,Klussmann JP

    更新日期:2010-11-01 00:00:00

  • Coexpression of hypoxia-inducible factor-1α and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients.

    abstract:AIMS:To study whether coexpression of the two hypoxia-related proteins hypoxia-inducible factor (HIF)-1α and glucose transporter (GLUT)-1 has prognostic relevance in oral squamous cell carcinomas (OSCCs). METHODS AND RESULTS:Eighty-two OSCC samples were analysed for expression levels of HIF-1α and GLUT-1 by immunohist...

    journal_title:Histopathology

    pub_type: 杂志文章

    doi:10.1111/j.1365-2559.2011.03806.x

    authors: Eckert AW,Lautner MH,Schütze A,Taubert H,Schubert J,Bilkenroth U

    更新日期:2011-06-01 00:00:00