Comparative study of soft tissue perineurioma and meningioma using a five-marker immunohistochemical panel.

abstract：AIMS:To examine cytokeratin, epithelial glycoprotein (mucin) and glycoprotein CD10 expression in benign mucinous cystdenomas (MCAs) in comparison with intraductal papillary mucinous adenomas (IPMAs). METHODS AND RESULTS:Thirty MCAs of the pancreas were analysed for immunohistochemical expression of cytokeratin (CK) 7,...

journal_title：Histopathology

authors： Handra-Luca A,Fléjou JF,Rufat P,Corcos O,Belghiti J,Ruszniewski P,Degott C,Bedossa P,Couvelard A

更新日期：2006-06-01 00:00:00

abstract：AIMS:Glypican 3 (GPC3) has been reported to be overexpressed in yolk sac tumour (YST), but the sensitivity has not been compared with alpha-fetoprotein (AFP). YST can form numerous growth patterns and the expression of GPC3 in these patterns has not been studied. The aim was to address these aspects. METHODS AND RESUL...

journal_title：Histopathology

authors： Zynger DL,McCallum JC,Luan C,Chou PM,Yang XJ

更新日期：2010-05-01 00:00:00

abstract：:Three cases are reported in which an initial diagnosis of the plasma cell variant of Castleman's disease was made, but in which a second lymph node biopsy within a year showed evidence of Hodgkin's disease. Review of the initial biopsy indicated that atypical CD15 and CD30 positive cells were present in the initial bi...

journal_title：Histopathology

authors： Maheswaran PR,Ramsay AD,Norton AJ,Roche WR

更新日期：1991-03-01 00:00:00

abstract：AIMS:Metastatic melanoma involving the epidermis and/or upper dermis may show significant histological overlap with primary cutaneous melanoma, especially the nodular subtype. Proper histopathological classification is crucial to appropriate staging and management, but is often challenging. The aim of this study was to...

journal_title：Histopathology

authors： Skala SL,Arps DP,Zhao L,Cha KB,Wang M,Harms PW,Andea AA,Fullen DR,Chan MP

更新日期：2018-02-01 00:00:00

abstract：:Thirty-two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries ...

journal_title：Histopathology

authors： Miller N,Bédard YC,Cooter NB,Shaul DL

更新日期：1986-07-01 00:00:00

abstract：:Lobular carcinoma in situ and atypical lobular hyperplasia were first described over 50 years ago. Despite this long incubation period, the biological nature of the lesions remains controversial. They are generally regarded as 'risk indicators' of invasive cancer rather than true precursor lesions. When first describe...

journal_title：Histopathology

authors： Lishman SC,Lakhani SR

更新日期：1999-09-01 00:00:00

abstract：AIMS:To investigate the prognostic significance of chromosomal alterations in colorectal cancer patients. Histopathological tumour classification is still considered to be the gold standard for the characterization of solid tumours. However, it is well known that such established parameters do not satisfactorily predic...

journal_title：Histopathology

authors： Knösel T,Schlüns K,Stein U,Schwabe H,Schlag PM,Dietel M,Petersen I

更新日期：2003-10-01 00:00:00

abstract：AIM:Combined hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) (cHCC-CC) is a rare biphasic liver cancer. Recent studies have demonstrated that cHCC-CC originates from hepatic progenitor cells (HPCs). Spalt-like transcription factor 4 (SALL4) is a marker for a progenitor subclass of HCC with an aggressive phen...

journal_title：Histopathology

authors： Tanaka Y,Aishima S,Kohashi K,Okumura Y,Wang H,Hida T,Kotoh K,Shirabe K,Maehara Y,Takayanagi R,Oda Y

更新日期：2016-04-01 00:00:00

abstract：:Thirty-two cases of mucoepidermoid carcinoma of the salivary glands were studied in order to characterize the expression of simple mucin-type carbohydrate antigens T, Tn and sialosyl-Tn and to evaluate its implication for tumour histogenesis. Monoclonal antibodies of known specificity were used on formalin-fixed, para...

journal_title：Histopathology

authors： Fonseca I,Costa Rosa J,Félix A,Therkildsen MH,Mandel U,Soares J

更新日期：1994-12-01 00:00:00

abstract：:Adhesion molecules are considered to have an important role in inflammatory reactions. We investigated the kinetics of ICAM-1 expression on keratinocytes and correlated this with the numbers of lymphocytes expressing LFA-1 in the dermis and epidermis of evolving allergic contact dermatitis reactions. In nickel-sensiti...

journal_title：Histopathology

authors： Garioch JJ,Mackie RM,Campbell I,Forsyth A

更新日期：1991-10-01 00:00:00

abstract：AIMS:Focal nodular hyperplasia-like lesions have rarely been described in cirrhotic livers. We describe five cases of such lesions. METHODS AND RESULTS:Between 1998 and 2001, 146 liver transplants were performed at the Royal Free Hospital for cirrhosis of the liver. Nodular lesions identified in the livers removed at ...

journal_title：Histopathology

authors： Quaglia A,Tibballs J,Grasso A,Prasad N,Nozza P,Davies SE,Burroughs AK,Watkinson A,Dhillon AP

更新日期：2003-01-01 00:00:00

abstract：:We report an unusual and possibly unique example of cerebral ganglioglioma with an anaplastic oligodendroglial component. The latter was documented on both morphological and immunohistochemical grounds. Immunohistochemically, the anaplastic cells were strongly positive with the monoclonal antibody anti-Leu-7, while th...

journal_title：Histopathology

authors： Allegranza A,Pileri S,Frank G,Ferracini R

更新日期：1990-11-01 00:00:00

abstract：AIMS:Calcific aortic stenosis is a progressive disease characterized by massive fibrosis andmineralization of the valve leaflets. The aim of this study was to determine whether the onset of native calcific aortic stenosis is associated primarily with matrix remodelling events, and particularly with elastin degradation....

journal_title：Histopathology

authors： Perrotta I,Russo E,Camastra C,Filice G,Di Mizio G,Colosimo F,Ricci P,Tripepi S,Amorosi A,Triumbari F,Donato G

更新日期：2011-09-01 00:00:00

abstract：AIMS:Regional differences in proliferative activity are commonly seen within breast cancers, but little is known on the extent of intratumoral heterogeneity of Ki67 expression. Our aim was to study the intratumoral heterogeneity of Ki67 expression in early breast cancers and its association with clinicopathological fea...

journal_title：Histopathology

authors： Focke CM,Decker T,van Diest PJ

更新日期：2016-11-01 00:00:00

abstract：:The CD30 antigen is a characteristic phenotypic feature of Sternberg-Reed and Hodgkin cells and is also found in a subset of large cell non-Hodgkin's lymphomas. The finding of CD30 positive cells in some centroblastic/centrocytic (cb/cc) follicular lymphomas prompted us to characterize the presence and distribution of...

journal_title：Histopathology

authors： Piris M,Gatter KC,Mason DY

更新日期：1991-01-01 00:00:00

abstract：AIMS:We report a series of five unusual subcutaneous lipomas characterized by prominent stromal sclerosis in a storiform arrangement. METHODS AND RESULTS:All lesions occurred in young male adults (23.0 +/- 9.5 years), three lesions were on the scalp and two on the hands. Clinically, lipoma, chondroma or some form of c...

journal_title：Histopathology

authors： Zelger BG,Zelger B,Steiner H,Rütten A

更新日期：1997-08-01 00:00:00

abstract：:We present a 27-year-old woman with non-systemic diffuse lymphangiomatosis of spleen and liver. The tumour consisted of capillary and cavernous lymphatic vessels located in abundant fibrous tissue. The vascular endothelium showed immunoreactivity for factor VIII-related antigen. A basal lamina could be demonstrated im...

journal_title：Histopathology

authors： Schmid C,Beham A,Uranüs S,Melzer G,Auböck L,Seewann HL,Klimpfinger M

更新日期：1991-05-01 00:00:00

abstract：:An ovarian and rectal carcinoid within the same person is described. The ovarian carcinoid is non-argentaffinic with typical regular granules. The rectal tumour consists of two types of APUD cells, some argentaffinic and diazo-positive, whilst others are non-argyrophilic. These features are mirrored ultrastructurally,...

journal_title：Histopathology

authors： Williams RM

更新日期：1979-01-01 00:00:00

abstract：AIMS:To examine the natural history of columnar-lined oesophagus with routinely diagnosed low-grade dysplasia and ascertain the risk of oesophageal adenocarcinoma development. METHODS AND RESULTS:A multicentre retrospective cohort study of 283 patients with low-grade dysplasia. Follow-up data were obtained from examin...

journal_title：Histopathology

authors： Gatenby P,Ramus J,Caygill C,Shepherd N,Winslet M,Watson A

更新日期：2009-06-01 00:00:00

abstract：:A case is reported of squamous carcinoma of the peri-anal region arising in a giant condyloma. In situ DNA hybridization showed human papillomavirus (HPV) types 6 and 11. These HPV types are commonly demonstrated in ano-genital condylomas but have not previously been reported in association with malignant change at th...

journal_title：Histopathology

authors： Wells M,Robertson S,Lewis F,Dixon MF

更新日期：1988-03-01 00:00:00

abstract：AIMS:In this study, we aimed to investigate the clinicopathological features of CD4+ and/or CD56+ immature haematolymphoid malignancy (iHLM), including blastic plasmacytoid dendritic cell neoplasm (BPDCN). METHODS AND RESULTS:We analysed the clinicopathological features of 46 patients diagnosed consecutively with CD4+...

journal_title：Histopathology

authors： Suzuki Y,Kato S,Kohno K,Satou A,Eladl AE,Asano N,Kono M,Kato Y,Taniwaki M,Akiyama M,Nakamura S

更新日期：2017-12-01 00:00:00

abstract：AIMS:Conflicting data on c-erbB-2 overexpression in gastric carcinomas can be found in the literature with regard to overall prevalence, prognostic significance and the histological type according to Lauren. The majority of these studies have focused on advanced gastric carcinomas whereas data on c-erbB-2 overexpressio...

journal_title：Histopathology

authors： Blok P,Craanen ME,Dekker W,Offerhaus GJ,Tytgat GN

更新日期：1998-04-01 00:00:00

abstract：AIMS:To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes. METHODS AND RESULTS:RAD51 expression identified immunohistochemically was compared between prostatic cancers occ...

journal_title：Histopathology

authors： Mitra A,Jameson C,Barbachano Y,Sanchez L,Kote-Jarai Z,Peock S,Sodha N,Bancroft E,Fletcher A,Cooper C,Easton D,IMPACT Steering Committee and IMPACT and EMBRACE Collaborators.,Eeles R,Foster CS

更新日期：2009-12-01 00:00:00

abstract：AIMS:  To review the histopathological features of cervical LNs, and to clarify the changes in extracervical LNs, in acute Kawasaki disease (KD). METHODS AND RESULTS:  The samples were obtained from 33 patients with acute-phase KD. We divided the LNs into those in the neck (n = 23) and those located elsewhere (n = 26)...

journal_title：Histopathology

authors： Yokouchi Y,Oharaseki T,Harada M,Ihara F,Naoe S,Takahashi K

更新日期：2013-02-01 00:00:00

abstract：AIMS:SOX11 is known as an essential transcription factor for regulating neurogenesis. Recently, SOX11 has been suggested to be a diagnostic marker and oncogene because of its significant expression in mantle cell lymphoma (MCL). However, SOX11 expression in other tumour types has not yet been extensively studied. METH...

journal_title：Histopathology

authors： Xu S,Dong Y,Huo Z,Yu L,Xue J,Wang G,Duan Y

更新日期：2019-02-01 00:00:00

abstract：:A series of 10 sweat-gland carcinomas is reported. The ages of the patients at presentation ranged from 12 to 79 years. Three of the tumours had shown long latent periods with a mass present for up to 20 years. Prognosis proved to be related to the histological subtype. Thus, two papillary syringocystadeno-carcinomas,...

journal_title：Histopathology

authors： Dissanayake RV,Salm R

更新日期：1980-07-01 00:00:00

abstract：AIMS:CD30 immunohistochemistry (IHC) in malignant lymphoma is used for selection of patients in clinical trials using brentuximab vedotin, an antibody drug-conjugate targeting the CD30 molecule. For reliable implementation in daily practice and meaningful selection of patients for clinical trials, information on techni...

journal_title：Histopathology

authors： Koens L,van de Ven PM,Hijmering NJ,Kersten MJ,Diepstra A,Chamuleau M,de Jong D

更新日期：2018-09-01 00:00:00

abstract：AIMS:High levels of autofluorescence in tissue samples can entirely mask specific labellings with fluorophores and thus impair immunofluorescence histochemistry. In pancreatic tissue samples we observed autofluorescence as a common problem often mediated by the fixation and processing procedure. METHODS AND RESULTS:Us...

journal_title：Histopathology

authors： Erben T,Ossig R,Naim HY,Schnekenburger J

更新日期：2016-09-01 00:00:00

abstract：AIMS:Evaluation of angiogenesis by intratumoral vessel profiles can be performed by different methods. The aim of this study was to investigate the prognostic value of estimates obtained by the intratumoral microvessel density (MVD) method and then to compare with corresponding estimates obtained by the Chalkley method...

journal_title：Histopathology

authors： Hansen S,Sørensen FB,Vach W,Grabau DA,Bak M,Rose C

更新日期：2004-05-01 00:00:00

abstract：AIMS:The recent recognition that ovarian carcinoma is composed of five distinct disease entities has served to increase the value of accurate histotyping. Reliable identification of histotypes is essential for the success of studies testing novel therapies, as well as for biomarker discovery research. The aim of this s...

journal_title：Histopathology

authors： Kommoss S,Gilks CB,Kommoss F,Chow C,Hilpert F,du Bois A,Köbel M,Huntsman DG,Anglesio M,Kalloger SE,Pfisterer J

更新日期：2013-11-01 00:00:00