Human pancreatic mucinous cystadenoma is characterized by distinct mucin, cytokeratin and CD10 expression compared with intraductal papillary-mucinous adenoma.

abstract：:In recent years the interaction between tumour cells and the surrounding extracellular matrix in the process of tumour development, invasion and metastasis has been a focus of interest. We studied frozen sections of nine naevocellular naevi (junctional, compound and intradermal), 40 dysplastic naevi, six pagetoid in s...

journal_title：Histopathology

authors： Van Duinen CM,Fleuren GJ,Bruijn JA

更新日期：1994-01-01 00:00:00

abstract：:Urothelial carcinoma of the urinary bladder is a heterogeneous disease with multiple possible treatment modalities and a wide spectrum of clinical outcome. Treatment decisions and prognostic expectations hinge on accurate and precise staging, and the recently published American Joint Committee on Cancer (AJCC) Staging...

journal_title：Histopathology

authors： Magers MJ,Lopez-Beltran A,Montironi R,Williamson SR,Kaimakliotis HZ,Cheng L

更新日期：2019-01-01 00:00:00

abstract：AIMS:To study relationships between the number of pseudomelanosis coli cells and that of colonic enteric neurons and interstitial cells of Cajal, which are significantly reduced compared with controls in severely constipated patients. Pseudomelanosis coli is frequent in patients using anthraquinone laxatives. It is not...

journal_title：Histopathology

authors： Villanacci V,Bassotti G,Cathomas G,Maurer CA,Di Fabio F,Fisogni S,Cadei M,Mazzocchi A,Salerni B

更新日期：2006-08-01 00:00:00

abstract：AIMS:We tried to improve the evaluation of E-cadherin immunostaining in paraffin sections, to distinguish the less aggressive variants of ductal infiltrating breast cancer from other variants. METHODS AND RESULTS:The method graded the membrane staining and estimated the fraction of area of cancer tissue stained at the...

journal_title：Histopathology

authors： Elzagheid A,Kuopio T,Ilmen M,Collan Y

更新日期：2002-08-01 00:00:00

abstract：:Primary intrathoracic sarcomas constitute a rare, heterogeneous group of neoplasms that occur in the lung parenchyma, pleura, and mediastinum. Although pathologically diverse, they frequently show similar clinical and radiological features, and accurate histopathological diagnosis is therefore crucial for correct mana...

journal_title：Histopathology

authors： Thway K,Jordan S,Fisher C,Nicholson AG

更新日期：2015-12-01 00:00:00

abstract：AIMS:The 2009 International Society of Urological Pathology consensus conference recommended reporting the extent of extraprostatic extension (EPE) for the prediction of outcome in prostate cancer. Our aim was to stratify EPE into prognostic groups. METHODS AND RESULTS:We reviewed 1051 radical prostatectomy (RP) speci...

journal_title：Histopathology

authors： Danneman D,Wiklund F,Wiklund NP,Egevad L

更新日期：2013-10-01 00:00:00

abstract：:Eleven hepatoblastomas of various subtypes and normal liver tissue were investigated with antibodies against collagen types I-VI, laminin, fibronectin and endothelial and macrophage-associated antigens. Epithelial hepatoblastoma cells, unlike non-neoplastic hepatocytes, exhibited intracellular immunoreactivity for var...

journal_title：Histopathology

authors： Ruck P,Kaiserling E

更新日期：1992-08-01 00:00:00

abstract：AIMS:Malignant transformation of Warthin's tumour (WT) is a rare event. We present two cases of mucoepidermoid carcinoma (MEC) arising in WT in the parotid gland. METHODS AND RESULTS:Two cases of MEC arising in WT, which were found in 185 cases of WT of the parotid gland, were investigated by light and electron micros...

journal_title：Histopathology

authors： Nagao T,Sugano I,Ishida Y,Tajima Y,Furuya N,Kondo Y,Nagao K

更新日期：1998-10-01 00:00:00

abstract：AIMS:Monocarboxylate transporters (MCTs) have been considered promising targets for cancer therapy, since they facilitate lactate efflux in glycolytic tumours. However, their role in solid tumours is still poorly understood. Thus, the present work aimed to contribute to understanding the involvement of MCT1 and MCT4 in...

journal_title：Histopathology

authors： Pinheiro C,Albergaria A,Paredes J,Sousa B,Dufloth R,Vieira D,Schmitt F,Baltazar F

更新日期：2010-06-01 00:00:00

abstract：AIMS:Progressive changes have been reported in lymph nodes in HIV infection, but few accounts describe altered splenic histology at different stages of the disease. Investigation of splenic changes accompanying the progressive CD4+ T-cell depletion that occurs in HIV infection could shed light on normal immunological i...

journal_title：Histopathology

authors： Wilkins BS,Davis Z,Lucas SB,Delsol G,Jones DB

更新日期：2003-02-01 00:00:00

abstract：AIMS:To validate the use of the silver-enhanced in situ hybridization (SISH) technique in assessing HER2 status of breast carcinoma in excision biopsy specimens, and to assess its reliability in determining HER2 status in core biopsy specimens. METHODS AND RESULTS:Routinely processed paraffin sections of 65 excised br...

journal_title：Histopathology

authors： Shousha S,Peston D,Amo-Takyi B,Morgan M,Jasani B

更新日期：2009-01-01 00:00:00

abstract：:Two patients are described in each of whom metastatic prostatic carcinoma presented as a tumour of the parotid gland. In one, primary prostate cancer had been diagnosed three years prior to the appearance of what was believed clinically to be an unrelated salivary lesion. In the other a neck swelling was the first ind...

journal_title：Histopathology

authors： Simpson RH,Skálová A

更新日期：1997-01-01 00:00:00

abstract：AIMS:In skull base chordoma, c-MET expression has been reported to correlate with younger patient age and favourable prognosis; however, it also contributes to tumour invasiveness, especially in recurrent lesions, suggesting variable roles for c-MET according to clinical status. The aim of this study was to investigate...

journal_title：Histopathology

authors： Naka T,Boltze C,Samii A,Samii M,Herold C,Ostertag H,Iwamoto Y,Oda Y,Tsuneyoshi M,Kuester D,Roessner A

更新日期：2009-04-01 00:00:00

abstract：:A case of squamous cell carcinoma of the lung showing extensive spindle transformation is presented. On light microscopy, the tumour showed sheets and fascicles of elongated fusiform cells resulting in a growth pattern which closely resembled a sarcoma. Immunocytochemistry using tissue-specific antibodies against inte...

journal_title：Histopathology

authors： Suster S,Huszar M,Herczeg E

更新日期：1987-08-01 00:00:00

abstract：AIM:Although the World Health Organization (WHO) histological criteria distinguishing benign from atypical and malignant meningioma are clear, discerning benign from atypical meningioma is still somewhat difficult, leading to interobserver diagnostic variability. Osteopontin (OPN) and cortactin play important roles in ...

journal_title：Histopathology

authors： Lin CK,Tsai WC,Lin YC,Hueng DY

更新日期：2012-01-01 00:00:00

abstract：:Germ cell tumours may imitate various structures of the developing embryo and foetus. Certain structures have, however, very rarely or never been observed in these tumours. Thus the presence of hepatic tissue in testicular germ cell tumours has not been reported. In a series of 37 non-seminomatous testicular tumours s...

journal_title：Histopathology

authors： Jacobsen GK,Jacobsen M

更新日期：1983-07-01 00:00:00

abstract：AIMS:BCOR-CCNB3 sarcoma is a genetically defined undifferentiated malignancy with Ewing sarcoma (ES)-like round cells, and preferentially affects the bones of male adolescents. Sarcomas harbouring BCOR-CCNB3 rarely arise from soft tissues; therefore, we aimed to report four cases to expand the clinicopathological spect...

journal_title：Histopathology

authors： Li WS,Liao IC,Wen MC,Lan HH,Yu SC,Huang HY

更新日期：2016-11-01 00:00:00

abstract：:We report three cases of an unusual primary carcinoma of the liver composed of small cells. The patients were adult males (56 to 89 years) who presented with jaundice, weight loss and abdominal discomfort. Surgery was attempted in one case. Clinical evolution was rapid, with death ensuing between 1 and 5 months after ...

journal_title：Histopathology

authors： Zanconati F,Falconieri G,Lamovec J,Zidar A

更新日期：1996-11-01 00:00:00

abstract：AIMS:Colonic and rectal biopsies, often taken from an endoscopically normal large bowel, form a significant proportion of the histopathology workload. The aim of this study was to determine diagnostic yield from mucosal biopsies in patients with normal colonoscopy or sigmoidoscopy, and whether or not diarrhoea is predi...

journal_title：Histopathology

authors： O'Mahony OH,Burgoyne M,Going JJ

更新日期：2012-12-01 00:00:00

abstract：AIMS:To assess MRP1 protein and MRP1 mRNA levels in gastric carcinomas and in non-neoplastic mucosa remote from the tumours. MRP1 gene expression may play a role in the complex pattern of chemoresistance present in gastric carcinomas. METHODS AND RESULTS:A total of 57 carcinomas and respective gastric tissues were inc...

journal_title：Histopathology

authors： Lacueva J,Perez-Ramos M,Soto JL,Oliver I,Andrada E,Medrano J,Perez-Vazquez T,Arroyo A,Carrato A,Ferragut JA,Calpena R

更新日期：2005-04-01 00:00:00

abstract：AIMS:Pulmonary fibrosis in acute and chronic lung disease has been much investigated, but little attention has been directed at the elastic tissue in these situations. Our aim was to verify whether elastic deposition accompanies collagen deposition in the repairing process of acute and chronic lung injury. METHODS AND...

journal_title：Histopathology

authors： Negri EM,Montes GS,Saldiva PH,Capelozzi VL

更新日期：2000-11-01 00:00:00

abstract：:An immunocytochemical and cytophotometrical analysis of 30 renal cell carcinomas was carried out in order to investigate the expression of cytokeratin and vimentin in relation to the ploidy and mitotic index. Thirty renal cell carcinomas were studied using monoclonal antibodies CAM 5.2 and anti-vimentin in a biotin-st...

journal_title：Histopathology

authors： Dierick AM,Praet M,Roels H,Verbeeck P,Robyns C,Oosterlinck W

更新日期：1991-04-01 00:00:00

abstract：AIMS:Angiogenesis is essential for tumour growth and metastasis and tumour necrosis factor (TNF)-alpha is a potent angiogenic factor. Invasive micropapillary carcinoma of the breast (IMPC), a rare subtype of breast cancer, possesses a lymphotropic nature with a high incidence of lymph node metastasis and poor prognosis...

journal_title：Histopathology

authors： Cui LF,Guo XJ,Wei J,Liu FF,Fan Y,Lang RG,Gu F,Zhang XM,Fu L

更新日期：2008-10-01 00:00:00

abstract：AIMS:Although delayed hypopituitarism is a common complication of conventional radiotherapy of sellar tumours, histological changes that may account for it have been rarely reported. To elucidate the changes, hypofunctional pituitary glands following irradiation were studied. METHODS AND RESULTS:Two pituitary glands o...

journal_title：Histopathology

authors： Nishioka H,Ito H,Haraoka J,Hirano A

更新日期：2001-06-01 00:00:00

abstract：AIMS:This study has compared the tissue expression of the p53 tumour suppressor protein and DNA repair proteins APE1, hMSH2 and ERCC1 in normal, dysplastic and malignant lip epithelium. METHODS AND RESULTS:Morphological analysis and immunohistochemistry were performed on archived specimens of normal lip mucosa (n=15),...

journal_title：Histopathology

authors： Souza LR,Fonseca-Silva T,Pereira CS,Santos EP,Lima LC,Carvalho HA,Gomez RS,Guimarães AL,De Paula AM

更新日期：2011-02-01 00:00:00

abstract：AIMS:Endometrial stromal sarcoma (ESS) has traditionally been divided into low and high grade, but the World Health Organization (WHO, 2003) has changed the definition. Since 2003, many studies have used the old criteria, and few have focused on WHO 2003-defined ESS low grade (ESS-LG). The aim of this study was to inve...

journal_title：Histopathology

authors： Feng W,Hua K,Gudlaugsson E,Yu Y,Zhou X,Baak JP

更新日期：2013-04-01 00:00:00

abstract：AIMS:To determine the frequency of point mutation in c-kit in CD117+ small cell lung cancer (SCLC). A significant proportion of SCLCs have been documented to be CD117+, thereby signifying they express the c-kit gene product. This finding suggests this tumour may be a potential target for tyrosine kinase inhibitor (TKI)...

journal_title：Histopathology

authors： Mojica WD,Saxena R,Starostik P,Cheney RT

更新日期：2005-11-01 00:00:00

abstract：AIMS:The morphological criteria for identification of intercalated duct lesions (IDLs) of salivary glands have been defined recently. It has been hypothesised that IDL could be a precursor of basal cell adenoma (BCA). BCAs show a variety of histological patterns, and the tubular variant is the one that presents the str...

journal_title：Histopathology

authors： Montalli VA,Martinez E,Tincani A,Martins A,Abreu Mdo C,Neves C,Costa AF,Araújo VC,Altemani A

更新日期：2014-05-01 00:00:00

abstract：AIMS:Outcomes of colorectal cancer (CRC) treatment and survival have steadily improved during the past decades, accompanied by an increased risk of developing second primary tumours and metastatic tumours at unusual sites. Metastatic CRC can show mucosal colonisation, thereby mimicking a second primary tumour. This pot...

journal_title：Histopathology

authors： de Bitter TJJ,van der Linden RLA,van Vliet S,Weren F,Sie D,Ylstra B,van der Linden HC,Knijn N,Ligtenberg MJL,van der Post RS,Simmer F,Nagtegaal ID

更新日期：2019-09-01 00:00:00

abstract：AIMS:The recent recognition that ovarian carcinoma is composed of five distinct disease entities has served to increase the value of accurate histotyping. Reliable identification of histotypes is essential for the success of studies testing novel therapies, as well as for biomarker discovery research. The aim of this s...

journal_title：Histopathology

authors： Kommoss S,Gilks CB,Kommoss F,Chow C,Hilpert F,du Bois A,Köbel M,Huntsman DG,Anglesio M,Kalloger SE,Pfisterer J

更新日期：2013-11-01 00:00:00