Glypican 3 has a higher sensitivity than alpha-fetoprotein for testicular and ovarian yolk sac tumour: immunohistochemical investigation with analysis of histological growth patterns.

abstract：AIMS:Cyclin D1 overexpression was examined in early gastric carcinomas and precursor lesions with the following aims; (1) to assess the chronology of cyclin D1 overexpression in various stages of gastric carcinogenesis, (2) to correlate cyclin D1 overexpression with the Lauren type, the grade of differentiation and the...

journal_title：Histopathology

authors： Blok P,Craanen ME,van Diest PJ,Dekker W,Tytgat GN

更新日期：2000-02-01 00:00:00

abstract：AIMS:Colorectal cancers deficient in DNA mismatch repair (MMR) are often characterized by the presence of numerous intraepithelial lymphocytes (IELs). These CD8+ T cells selectively express CD103, which is upregulated locally by transforming growth factor (TGF)-beta, and adhere to E-cadherin expressed by mucosal epithe...

journal_title：Histopathology

authors： Baker K,Chong G,Foulkes WD,Jass JR

更新日期：2006-10-01 00:00:00

abstract：:The clinical and pathological features of three adnexal tumours of probable Wolffian origin are reported. One case was an incidental finding in a patient who died from ovarian carcinoma; in the other two cases the patients presented with lower abdominal pain. The three tumours were well-circumscribed, solid masses ari...

journal_title：Histopathology

authors： Rahilly MA,Williams AR,Krausz T,al Nafussi A

更新日期：1995-01-01 00:00:00

abstract：:The use of percutaneous renal tumour biopsy (RTB) as a diagnostic tool for the histological characterization of renal masses has increased dramatically within the last 30 years. This increased utilization has paralleled advances in imaging techniques and an evolving knowledge of the clinical value of nephron sparing s...

journal_title：Histopathology

authors： Delahunt B,Samaratunga H,Martignoni G,Srigley JR,Evans AJ,Brunelli M

更新日期：2014-09-01 00:00:00

abstract：:We have investigated the immunohistochemical expression of p53 protein in 96 cases of non-Hodgkin's lymphoma using a panel of five antibodies. Positive neoplastic cells were found in 30 (31.2%) cases, which could be divided into two groups according to their patterns of reactivity with the different antibodies; i.e. t...

journal_title：Histopathology

authors： Pezzella F,Morrison H,Jones M,Gatter KC,Lane D,Harris AL,Mason DY

更新日期：1993-01-01 00:00:00

abstract：:Nineteen out of 121 consecutive cardiac biopsies from 107 patients were found to contain amyloid deposits on routine Congo red screening. Seventeen were left atrial appendages removed during mitral valvotomy for chronic rheumatic mitral valve disease while the remaining two were right atrial appendages excised during ...

journal_title：Histopathology

authors： Looi LM

更新日期：1981-11-01 00:00:00

abstract：AIMS:The aim of this study was to examine clinicopathological features of patients with core biopsy diagnoses of ductal carcinoma in situ (DCIS) that may predict invasion on subsequent excision, as upstaging has significant implications regarding the need for axillary staging via sentinel lymph node biopsy (SLNB). MET...

journal_title：Histopathology

authors： Walters LL,Pang JC,Zhao L,Jorns JM

更新日期：2015-03-01 00:00:00

abstract：AIMS:To study three atypical glioneuronal tumours (GNTs), in order to shed light on the clinical and pathological features of this diverse tumour group. METHODS AND RESULTS:Clinical and neuropathological data for each case were retrospectively reviewed. Case 1 involved a 17-year-old boy with left leg movement difficul...

journal_title：Histopathology

authors： Chen SY,Wang W,Wang LM,Lin QT,Zhao GG,Xu G,Lu DH,Piao YS

更新日期：2016-02-01 00:00:00

abstract：:Pancreatic acinar metaplasia of the gastric mucosa is a newly recognized entity. Its physiological relevance and association with other pathological conditions in the stomach remain to be elucidated. We studied by immunohistochemistry the expression of growth markers in the gastric mucosa in biopsies from 15 patients ...

journal_title：Histopathology

authors： Stachura J,Konturek J,Urbańczyk K,Bogdal J,Domschke W

更新日期：1995-12-01 00:00:00

abstract：AIM:We describe the unusual association of fallopian tubal prolapse and herpetic infection, an occurrence not previously reported to our knowledge. METHODS AND RESULTS:A 37-year-old woman presented with a small polypoid mass of the vaginal vault, 3 months after abdominal hysterectomy and abdominoplasty. The vaginal ma...

journal_title：Histopathology

authors： Lefrancq T,Orain I,Michalak S,Hourseau M,Fetissof F

更新日期：1999-06-01 00:00:00

abstract：AIMS:Development of effective immune-based therapies for patients with non-small-cell lung carcinoma (NSCLC) depends on an accurate characterization of complex interactions that occur between immune cells and the tumour environment. METHODS AND RESULTS:Innate and adaptive immune responses were evaluated in relation to...

journal_title：Histopathology

authors： da Costa Souza P,Parra ER,Atanazio MJ,da Silva OB,Noleto GS,Ab'Saber AM,de Morais Fernezlian S,Takagaki T,Capelozzi VL

更新日期：2012-10-01 00:00:00

abstract：AIMS:Diffuse large B-cell lymphoma (DLBCL) usually proliferates effacing lymph follicles. In occasional cases, tumour cells show an interfollicular pattern of proliferation preserving lymph follicles. The aim was to analyse clinicopathological findings in DLBCL showing an interfollicular pattern of proliferation to det...

journal_title：Histopathology

authors： Yamauchi A,Ikeda J,Nakamichi I,Kohara M,Fukuhara S,Hino M,Kanakura Y,Ogawa H,Sugiyama H,Kanamaru A,Aozasa K,Osaka Lymphoma Study Group.

更新日期：2008-05-01 00:00:00

abstract：:Three cases are reported in which an initial diagnosis of the plasma cell variant of Castleman's disease was made, but in which a second lymph node biopsy within a year showed evidence of Hodgkin's disease. Review of the initial biopsy indicated that atypical CD15 and CD30 positive cells were present in the initial bi...

journal_title：Histopathology

authors： Maheswaran PR,Ramsay AD,Norton AJ,Roche WR

更新日期：1991-03-01 00:00:00

abstract：:Forty cases of the distinctive but poorly recognized aneurysmal variant of cutaneous fibrous histiocytoma are described. These tumours presented most commonly in middle-age adults, with a slight predilection for females. Anatomical distribution was wide with most cases occurring in the lower limb/limb girdle (50%), up...

journal_title：Histopathology

authors： Calonje E,Fletcher CD

更新日期：1995-04-01 00:00:00

abstract：AIMS:Fibroadenomas (FAs) and phyllodes tumours (PTs) are fibroepithelial tumours. Mutations in MED12 exon 2 have been reported in FAs. This study investigated the MED12 mutations in a spectrum of fibroepithelial tumours. METHODS AND RESULTS:Using direct sequencing, we analysed MED12 exon 2 mutations on 121 samples, in...

journal_title：Histopathology

authors： Lien HC,Huang CS,Yang YW,Jeng YM

更新日期：2016-02-01 00:00:00

abstract：AIM:To clarify the prognosis of melanotic schwannoma. This is a rare tumour which is generally considered as a benign lesion, reported in many cases with a short follow-up only. METHODS AND RESULTS:Five cases of spinal melanotic schwannoma were retrospectively studied. The tumours were examined using standard histolog...

journal_title：Histopathology

authors： Vallat-Decouvelaere AV,Wassef M,Lot G,Catala M,Moussalam M,Caruel N,Mikol J

更新日期：1999-12-01 00:00:00

abstract：:Delta hepatitis (HDV) infection can only occur in the presence of hepatitis B (HBV) infection, as HDV requires a coat of HBV surface antigen (HBsAg) for assembly of complete virus. A number of studies have examined the variation of HBV markers in serum and liver during establishment of HDV infection, but none has syst...

journal_title：Histopathology

authors： Ryley NG,Heryet AR,Goldin R,Monjardino J,Saldanha J,Fleming KA

更新日期：1992-04-01 00:00:00

abstract：AIMS:p53 immunostaining in Barrett's oesophagus (BO) has been shown to be predictive of progression, but data regarding its generalizability to routine practice are lacking. This study compared the reliability of p53 and dysplasia interpretation and grading. METHODS AND RESULTS:Seventy-two cases encompassing the full ...

journal_title：Histopathology

authors： Kaye PV,Ilyas M,Soomro I,Haider SA,Atwal G,Menon S,Gill S,Richards C,Harrison R,West K,Ragunath K

更新日期：2016-09-01 00:00:00

abstract：AIMS:Endometrial stromal sarcoma (ESS) has traditionally been divided into low and high grade, but the World Health Organization (WHO, 2003) has changed the definition. Since 2003, many studies have used the old criteria, and few have focused on WHO 2003-defined ESS low grade (ESS-LG). The aim of this study was to inve...

journal_title：Histopathology

authors： Feng W,Hua K,Gudlaugsson E,Yu Y,Zhou X,Baak JP

更新日期：2013-04-01 00:00:00

abstract：:Signet ring cell differentiation in adenocarcinoma of the prostate is uncommon. In a review of 200 cases of prostatic carcinoma, we identified five cases with this change, all in moderately to poorly differentiated prostatic carcinomas. The signet ring cells in prostatic carcinoma contain an intracytoplasmic lumen, sh...

journal_title：Histopathology

authors： Guerin D,Hasan N,Keen CE

更新日期：1993-04-01 00:00:00

abstract：AIMS:Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) is a downstream effector of Ras signalling, and is overexpressed in several types of human malignancy. However, its role in gastric cancer remains unclear. The aim of this study was to investigate the prognostic significance of G3BP1 in gastric can...

journal_title：Histopathology

authors： Min L,Ruan Y,Shen Z,Jia D,Wang X,Zhao J,Sun Y,Gu J

更新日期：2015-11-01 00:00:00

abstract：AIMS:This study has compared the tissue expression of the p53 tumour suppressor protein and DNA repair proteins APE1, hMSH2 and ERCC1 in normal, dysplastic and malignant lip epithelium. METHODS AND RESULTS:Morphological analysis and immunohistochemistry were performed on archived specimens of normal lip mucosa (n=15),...

journal_title：Histopathology

authors： Souza LR,Fonseca-Silva T,Pereira CS,Santos EP,Lima LC,Carvalho HA,Gomez RS,Guimarães AL,De Paula AM

更新日期：2011-02-01 00:00:00

abstract：:Muciphages (mucin-containing macrophages), first described in 1966 by Azzopardi & Evans, are a common feature of biopsies of large intestinal mucosa, even in the absence of other abnormalities such as active inflammation or evidence of chronic inflammatory bowel disease. Should they be mentioned in diagnostic reports?...

journal_title：Histopathology

authors： Shepherd NA

更新日期：2000-06-01 00:00:00

abstract：AIMS:To look for FOXL2 mutation in rare ovarian epithelial lesions showing stromal components with morphological features of adult granulosa cell tumour (AGCT). METHODS AND RESULTS:We report the 402C→G FOXL2 mutation status in five epithelial ovarian lesions in women aged 45-77 years showing stromal proliferations tha...

journal_title：Histopathology

authors： Singh N,Gilks CB,Huntsman DG,Smith JH,Coutts M,Ganesan R,McCluggage WG

更新日期：2014-04-01 00:00:00

abstract：AIMS:The recent recognition that ovarian carcinoma is composed of five distinct disease entities has served to increase the value of accurate histotyping. Reliable identification of histotypes is essential for the success of studies testing novel therapies, as well as for biomarker discovery research. The aim of this s...

journal_title：Histopathology

authors： Kommoss S,Gilks CB,Kommoss F,Chow C,Hilpert F,du Bois A,Köbel M,Huntsman DG,Anglesio M,Kalloger SE,Pfisterer J

更新日期：2013-11-01 00:00:00

abstract：AIMS:Primary clear cell carcinoma of the pancreas resembling metastatic renal carcinoma has only rarely been described. To date it has been poorly characterized as a distinct tumour entity. METHODS AND RESULTS:We report a case of clear cell carcinoma in a 53-year-old man involving the head of the pancreas and which ha...

journal_title：Histopathology

authors： Lüttges J,Vogel I,Menke M,Henne-Bruns D,Kremer B,Klöppel G

更新日期：1998-05-01 00:00:00

abstract：:While the histological grade of a renal cell carcinoma is of prognostic significance there is poor concordance amongst pathologists in the use of these grading systems. Many grading systems have been described, but none has achieved widespread acceptance. The objective of this study was to assess the degree of interob...

journal_title：Histopathology

authors： Lanigan D,Conroy R,Barry-Walsh C,Loftus B,Royston D,Leader M

更新日期：1994-05-01 00:00:00

abstract：AIMS:Rare gastric lesions composed of a combined proliferation of chief and oxyntic cells have been variably called adenocarcinoma of fundic gland type and oxyntic gland polyp/adenoma. Herein, we present a series of cases that show a morphological spectrum of chief and oxyntic cell proliferations. METHODS AND RESULTS:...

journal_title：Histopathology

authors： Chan K,Brown IS,Kyle T,Lauwers GY,Kumarasinghe MP

更新日期：2016-05-01 00:00:00

abstract：AIMS:Early recognition and accurate diagnosis underpins melanoma survival. Identifying early melanomas arising in association with pre-existing lesions is often challenging. Clinically suspicious foci, however small, must be identified and examined histologically. This study assessed the accuracy of punch biopsy 'scori...

journal_title：Histopathology

authors： Grogan J,Cooper CL,Dodds TJ,Guitera P,Menzies SW,Scolyer RA

更新日期：2018-01-01 00:00:00

abstract：AIMS:To document the clinical, light microscopic, immunohistochemical and ultrastructural features of four cases of extra-orbital giant cell angiofibromas. METHODS AND RESULTS:Sections of formalin-fixed paraffin-embedded specimens were studied by haematoxylin and eosin, reticulin and immunohistochemical stains. Electr...

journal_title：Histopathology

authors： Thomas R,Banerjee SS,Eyden BP,Shanks JH,Bisset DL,Hunt R,Byers RJ,Oogarah P,Harris M

更新日期：2001-10-01 00:00:00