Diffuse lung disease in infancy and childhood: expanding the chILD classification.

abstract：AIMS:To examine how accurately immunohistochemical markers discriminate between pancreatobiliary and intestinal-type adenocarcinomas in the pancreatic head and to explore the prognostic importance of these markers among each of these histological types. METHODS AND RESULTS:Histopathological features of 114 consecutive...

journal_title：Histopathology

authors： Westgaard A,Schjølberg AR,Cvancarova M,Eide TJ,Clausen OP,Gladhaug IP

更新日期：2009-02-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is an unusual malignancy in that the tumour cells, the Hodgkin and Reed-Sternberg (HRS) cells, are a minor component of the tumour mass, the bulk of which is a mixed cellular infiltrate. There is compelling evidence that HRS cells are clonal B cells that have lost their B cell phenotype. Mature B...

journal_title：Histopathology

authors： Farrell K,Jarrett RF

更新日期：2011-01-01 00:00:00

abstract：AIMS:To investigate whether localization of beta-catenin is helpful in differentiating primary ovarian mucinous carcinoma and colorectal adenocarcinoma metastatic to the ovary. Extra-ovarian cancers which metastasize to the ovaries, especially from colorectal adenocarcinoma, frequently mimic primary ovarian carcinomas,...

journal_title：Histopathology

authors： Chou YY,Jeng YM,Kao HL,Chen T,Mao TL,Lin MC

更新日期：2003-08-01 00:00:00

abstract：:Three odontogenic cysts, two of dentigerous and one of dental type, are reported in which large numbers of cells containing autofluorescent granules were present, in both the capsule and cyst lining. Histochemical and electron microscopical studies suggest that the granules are composed of lipofuscin. Examination of 3...

journal_title：Histopathology

authors： Browne RM,Rippin JW

更新日期：1984-11-01 00:00:00

abstract：:Nineteen out of 121 consecutive cardiac biopsies from 107 patients were found to contain amyloid deposits on routine Congo red screening. Seventeen were left atrial appendages removed during mitral valvotomy for chronic rheumatic mitral valve disease while the remaining two were right atrial appendages excised during ...

journal_title：Histopathology

authors： Looi LM

更新日期：1981-11-01 00:00:00

abstract：AIMS:Focal nodular hyperplasia-like lesions have rarely been described in cirrhotic livers. We describe five cases of such lesions. METHODS AND RESULTS:Between 1998 and 2001, 146 liver transplants were performed at the Royal Free Hospital for cirrhosis of the liver. Nodular lesions identified in the livers removed at ...

journal_title：Histopathology

authors： Quaglia A,Tibballs J,Grasso A,Prasad N,Nozza P,Davies SE,Burroughs AK,Watkinson A,Dhillon AP

更新日期：2003-01-01 00:00:00

abstract：AIMS:Different methods to substage extraprostatic extension (EPE) were correlated with biochemical recurrence (BCR) after radical prostatectomy (RP). METHODS AND RESULTS:  A total of 157 consecutive RP specimens with EPE were completely embedded. Twenty-three patients with adjuvant therapy or detectable postoperative ...

journal_title：Histopathology

authors： van Veggel BA,van Oort IM,Witjes JA,Kiemeney LA,Hulsbergen-van de Kaa CA

更新日期：2011-10-01 00:00:00

abstract：AIMS:The majority of patients with Down syndrome (DS), trisomy 21, have morphologically abnormal thymuses and present with intrinsic immunological abnormalities affecting mainly the cellular immune response. The aim of this study was to examine whether the expression of functionally important molecules is altered in th...

journal_title：Histopathology

authors： Tomaru U,Tsuji T,Kiuchi S,Ishizu A,Suzuki A,Otsuka N,Ito T,Ikeda H,Fukasawa Y,Kasahara M

更新日期：2015-08-01 00:00:00

abstract：:Fine needle aspiration (FNA) cytology is a valuable aid to diagnosis and tumour staging in patients with non-Hodgkin's lymphoma. These tumours are often multicentric and involve sites such as the liver or the spleen which are not easily accessible to surgical biopsy. Particularly with splenic involvement, there is a d...

journal_title：Histopathology

authors： Johnson A,Akerman M,Cavallin-Ståhl E

更新日期：1987-06-01 00:00:00

abstract：:A total of 144 gastric biopsies colonized by Helicobacter-like organisms were studied under light and differential interference contrast microscopy for the modes of bacterial colonization. Biopsies were also graded for the degree of epithelial damage (epithelial-damage-grade: 0 to 6, in ascending order of severity) an...

journal_title：Histopathology

authors： Chan WY,Hui PK,Leung KM,Thomas TM

更新日期：1992-12-01 00:00:00

abstract：AIMS:Y-box binding protein-1 (YB-1) is known to modulate gene transcription and protein translation, as well as cellular response to drug treatment. The aim of this study is to correlate YB-1 protein expression levels with clinicopathological parameters in intestinal-type gastric cancer tissue samples (as categorized b...

journal_title：Histopathology

authors： Guo T,Yu Y,Yip GW,Baeg GH,Thike AA,Lim TK,Tan PH,Matsumoto K,Bay BH

更新日期：2015-03-01 00:00:00

abstract：AIM:To assess a new HER2 fluorescence in situ hybridization (FISH) test and report on multicentre intrasite and intersite variation. METHODS AND RESULTS:HER2 results were scored from 45 breast cancers in eight laboratories using the Kreatech Poseidon HER2 FISH probe (Kreatech Diagnostics, Amsterdam, the Netherlands). ...

journal_title：Histopathology

authors： Bartlett JM,Campbell FM,Ibrahim M,Thomas J,Wencyk P,Ellis I,Kay E,Connolly Y,O'Grady A,Barnett S,Starczynski J,Cunningham P,Miller K

更新日期：2010-02-01 00:00:00

abstract：AIMS:To assess the interobserver agreement in the reporting of colorectal polyps among histopathologists participating in the Welsh Bowel Cancer Screening (BCS) programme. METHODS AND RESULTS:Twelve benign polyps representative of BCS cases were identified from pathology files and reported by 28 BCS histopathologists ...

journal_title：Histopathology

authors： Turner JK,Williams GT,Morgan M,Wright M,Dolwani S

更新日期：2013-05-01 00:00:00

abstract：:Two patients are described in each of whom metastatic prostatic carcinoma presented as a tumour of the parotid gland. In one, primary prostate cancer had been diagnosed three years prior to the appearance of what was believed clinically to be an unrelated salivary lesion. In the other a neck swelling was the first ind...

journal_title：Histopathology

authors： Simpson RH,Skálová A

更新日期：1997-01-01 00:00:00

abstract：:The inflammatory infiltrate has been characterized in 10 cases of ovarian dysgerminoma using a panel of antisera to T-cells, B-cells and macrophages. The expression of Class II major histocompatibility complex (MHC) antigens and the distribution of interferons alpha and gamma were also examined. T-lymphocytes were pre...

journal_title：Histopathology

authors： Stewart CJ,Farquharson MA,Foulis AK

更新日期：1992-06-01 00:00:00

abstract：:We report a case of oesophageal carcinosarcoma with prominent rhabdomyoblastic differentiation. Immunohistochemically, the rhabdomyblasts were mainly reactive to vimentin, cytokeratin, desmin, muscle-specific actin, myosin, and myoglobin, and were surrounded by laminin and type IV collagen-positive basement membranes....

journal_title：Histopathology

authors： Guarino M,Reale D,Micoli G,Forloni B

更新日期：1993-05-01 00:00:00

abstract：AIMS:Colonic and rectal biopsies, often taken from an endoscopically normal large bowel, form a significant proportion of the histopathology workload. The aim of this study was to determine diagnostic yield from mucosal biopsies in patients with normal colonoscopy or sigmoidoscopy, and whether or not diarrhoea is predi...

journal_title：Histopathology

authors： O'Mahony OH,Burgoyne M,Going JJ

更新日期：2012-12-01 00:00:00

abstract：:Primary intrathoracic sarcomas constitute a rare, heterogeneous group of neoplasms that occur in the lung parenchyma, pleura, and mediastinum. Although pathologically diverse, they frequently show similar clinical and radiological features, and accurate histopathological diagnosis is therefore crucial for correct mana...

journal_title：Histopathology

authors： Thway K,Jordan S,Fisher C,Nicholson AG

更新日期：2015-12-01 00:00:00

abstract：AIMS:The Notch signalling pathway is involved in normal development as well as tumorigenesis. However, it is unclear whether Notch activation is related to diverse clinicopathological factors in papillary thyroid carcinoma (PTC). METHODS AND RESULTS:We examined the relationship between clinicopathological factors and ...

journal_title：Histopathology

authors： Jung CW,Kong JS,Seol H,Park S,Koh JS,Lee SS,Kim MJ,Choi IJ,Myung JK

更新日期：2017-01-01 00:00:00

abstract：:A series of 115 consecutive, non-ulcerous, dyspeptic patients were examined for Helicobacter pylori (H. pylori) colonization in the gastric antral and/or body mucosa using Giemsa staining. Findings were correlated with the presence and degree of activity of superficial gastritis, deep gastritis, atrophic gastritis and...

journal_title：Histopathology

authors： Rugge M,Di Mario F,Cassaro M,Baffa R,Farinati F,Rubio J Jr,Ninfo V

更新日期：1993-01-01 00:00:00

abstract：AIMS:The diagnosis of polymorphous low-grade adenocarcinoma (PLGA) remains difficult for general pathologists, particularly in cases of small biopsy samples. We aimed to characterize the histopathological spectrum and immunohistochemical aspects by using an accessible immunohistochemical panel of cytoskeletal proteins ...

journal_title：Histopathology

authors： Sedassari BT,Dos Santos HT,Pigatti FM,Martins Mussi MC,Tobouti PL,Altemani A,Sousa S

更新日期：2016-06-01 00:00:00

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a member of the lipocalin superfamily. Although its overexpression in various cancers has been reported, little is known about its expression and clinical significance in oral squamous cell carcinoma (OSCC). This study aimed to elucidate the clinical significanc...

journal_title：Histopathology

authors： Shinriki S,Jono H,Ueda M,Obayashi K,Nakamura T,Ota K,Ota T,Sueyoshi T,Guo J,Hayashi M,Hiraki A,Nakayama H,Yamashita S,Shinohara M,Ando Y

更新日期：2014-02-01 00:00:00

abstract：AIMS:Fibroadenomas (FAs) and phyllodes tumours (PTs) are fibroepithelial tumours. Mutations in MED12 exon 2 have been reported in FAs. This study investigated the MED12 mutations in a spectrum of fibroepithelial tumours. METHODS AND RESULTS:Using direct sequencing, we analysed MED12 exon 2 mutations on 121 samples, in...

journal_title：Histopathology

authors： Lien HC,Huang CS,Yang YW,Jeng YM

更新日期：2016-02-01 00:00:00

abstract：AIMS:bcl-2-associated transcription factor 1 (BCLAF1) is a nuclear protein that binds to bcl-related proteins and can induce apoptosis and autophagy. The aim of this study was to investigate the expression of BCLAF1 in a series of rectal cancers following neoadjuvant therapy. METHODS AND RESULTS:Immunohistochemistry w...

journal_title：Histopathology

authors： Brown GT,Cash B,Alnabulsi A,Samuel LM,Murray GI

更新日期：2016-03-01 00:00:00

abstract：AIMS:SMAD4 acts as a tumour suppressor, and the loss of SMAD4 is associated with poor prognosis in colorectal cancer (CRC) patients. Although next-generation sequencing (NGS) enabled us to detect numerous genetic alterations in a single assay, the clinical significance of SMAD4 alteration detected with NGS has not been...

journal_title：Histopathology

authors： Oyanagi H,Shimada Y,Nagahashi M,Ichikawa H,Tajima Y,Abe K,Nakano M,Kameyama H,Takii Y,Kawasaki T,Homma KI,Ling Y,Okuda S,Takabe K,Wakai T

更新日期：2019-05-01 00:00:00

abstract：AIMS:To assess MRP1 protein and MRP1 mRNA levels in gastric carcinomas and in non-neoplastic mucosa remote from the tumours. MRP1 gene expression may play a role in the complex pattern of chemoresistance present in gastric carcinomas. METHODS AND RESULTS:A total of 57 carcinomas and respective gastric tissues were inc...

journal_title：Histopathology

authors： Lacueva J,Perez-Ramos M,Soto JL,Oliver I,Andrada E,Medrano J,Perez-Vazquez T,Arroyo A,Carrato A,Ferragut JA,Calpena R

更新日期：2005-04-01 00:00:00

abstract：:A case is reported of nodular lymphocyte predominant Hodgkin's disease arising 13 years after the removal of a lymph node from the same site which showed marked progressive transformation of germinal centres. The morphological evidence for a histogenetic relationship between the two conditions is presented and discuss...

journal_title：Histopathology

authors： Crossley B,Heryet A,Gatter KC

更新日期：1987-06-01 00:00:00

abstract：:Urothelial carcinoma of the urinary bladder is a heterogeneous disease with multiple possible treatment modalities and a wide spectrum of clinical outcome. Treatment decisions and prognostic expectations hinge on accurate and precise staging, and the recently published American Joint Committee on Cancer (AJCC) Staging...

journal_title：Histopathology

authors： Magers MJ,Lopez-Beltran A,Montironi R,Williamson SR,Kaimakliotis HZ,Cheng L

更新日期：2019-01-01 00:00:00

abstract：AIMS:Colorectal carcinoma (CRC) with micropapillary (MP) features has only been described recently and is still being characterized. METHODS AND RESULTS:We reviewed the clinicopathological and molecular features of 42 CRC with MP features. Twenty-nine cases were also evaluated for immunohistochemical evidence of epith...

journal_title：Histopathology

authors： Gonzalez RS,Huh WJ,Cates JM,Washington K,Beauchamp RD,Coffey RJ,Shi C

更新日期：2017-01-01 00:00:00

abstract：:Valve replacement started in 1960, with the surgeon now having a significant variety of prosthetic heart valves from which to choose. These valves are broadly divided into mechanical heart valves (MHV) and bioprosthetic heart valves (BHV). Improvements in the performance and ease of usage of BHV without the need for a...

journal_title：Histopathology

authors： Siddiqui RF,Abraham JR,Butany J

更新日期：2009-08-01 00:00:00