Hairy leukoplakia--a histological study.

abstract：:Four cases of endocrine neoplasia within fibroadenomas of the breast are described. The tumours are identifiable by light microscopic, silver impregnation and ultrastructural studies. Argyrophilia and the presence of dense-core granules establish the identity of this tumour type. The differential diagnosis from, and p...

journal_title：Histopathology

authors： Eusebi V,Azzopardi JG

更新日期：1980-07-01 00:00:00

abstract：AIMS:Helicobacter pylori has been claimed to be an important aetiological factor which raises the risk of mucosa-associated tissue lymphoid (MALT) lymphoma. However, some studies on gastric MALT lymphoma revealed a low rate of H. pylori infection suggesting that not all gastric lymphomas are related to H. pylori infect...

journal_title：Histopathology

authors： Bouzourene H,Haefliger T,Delacretaz F,Saraga E

更新日期：1999-02-01 00:00:00

abstract：AIMS:To clarify the lineage-specific carcinogenesis of gland-forming gastric neoplasms, by characterizing mucin phenotypes and proliferation patterns immunohistochemically using monoclonal antibodies against MUC2, MUC5AC, MUC6, CD10 and Ki67. METHODS AND RESULTS:We analysed 49 gland-forming intramucosal neoplasms, inc...

journal_title：Histopathology

authors： Nishimura R,Mukaisho K,Yamamoto H,Sonoda A,Andoh A,Fujiyama Y,Hattori T,Sugihara H

更新日期：2013-11-01 00:00:00

abstract：AIMS:There is increasing evidence of Gleason score (GS) drift in prostatic core biopsies during the last two decades. The ProtecT study is a randomized controlled study and provides an excellent cohort to study the effect of time, prostate-specific antigen (PSA) level, perineural invasion, tumour length and age on GS. ...

journal_title：Histopathology

authors： Oxley J,Simpkin A,Goepel J,Varma M,Griffiths D,Grigor K,Mayer N,Warren A,Deshmukh N,Bhattarai S,Dormer J,Hounsome L,Adamczyk LA,Metcalfe C,Lane JA,Davis M,Donovan JL,Neal DE,Hamdy FC,Robinson MC,ProtecT Study Grou

更新日期：2015-02-01 00:00:00

abstract：AIMS:Primary pulmonary sarcoma is rare, and frequently creates diagnostic challenges. We describe two cases of primary pulmonary spindle cell sarcoma in which a molecular approach using archival paraffin-embedded tissue was proved to aid diagnosis. METHODS AND RESULTS:Both patients had huge masses replacing the upper ...

journal_title：Histopathology

authors： Hisaoka M,Hashimoto H,Iwamasa T,Ishikawa K,Aoki T

更新日期：1999-03-01 00:00:00

abstract：AIMS:In nodular sclerosing Hodgkin's disease (NSHD), the prognostic relevance of the histopathological grading in two subtypes NSI (low-grade) and NSII (high-grade) remains controversial. Analysis of follicular dendritic cells (FDC) may provide new prognostic parameters. METHODS AND RESULTS:Tumours from 59 patients wi...

journal_title：Histopathology

authors： Baur AS,Meugé-Moraw C,Michel G,Delacrétaz F

更新日期：1998-06-01 00:00:00

abstract：AIMS:Primary sclerosing cholangitis (PSC) is characterized histologically by portal inflammation, bile duct injury and regeneration and concentric periductal fibrosis. Although seen commonly in our experience, the significance of histological thickening of the bile duct basement membrane on periodic acid Schiff (PAS)-p...

journal_title：Histopathology

authors： Colling R,Verrill C,Fryer E,Kartsonaki C,Wang LM,Chapman R,Rajabally N,Fleming K

更新日期：2016-05-01 00:00:00

abstract：AIMS:Prognostic factors affecting survival in cases of leiomyosarcoma of soft parts were investigated in this study. METHODS AND RESULTS:A retrospective study of 267 patients was carried out. This group comprised 142 females (53%) and 125 males (47%), whose ages ranged from 7 to 95 years (median 58 years). One hundred...

journal_title：Histopathology

authors： Miyajima K,Oda Y,Oshiro Y,Tamiya S,Kinukawa N,Masuda K,Tsuneyoshi M

更新日期：2002-04-01 00:00:00

abstract：AIMS:Follicular lymphoma (FL) in situ is defined as strongly bcl-2-positive B cells in germinal centres of morphologically inconspicuous lymph nodes. The prevalence and biological and clinical significance of this lesion are still not clear. Therefore we aimed at the detection of the prevalence of this phenomenon in an...

journal_title：Histopathology

authors： Henopp T,Quintanilla-Martínez L,Fend F,Adam P

更新日期：2011-07-01 00:00:00

abstract：AIMS:Focal nodular hyperplasia-like lesions have rarely been described in cirrhotic livers. We describe five cases of such lesions. METHODS AND RESULTS:Between 1998 and 2001, 146 liver transplants were performed at the Royal Free Hospital for cirrhosis of the liver. Nodular lesions identified in the livers removed at ...

journal_title：Histopathology

authors： Quaglia A,Tibballs J,Grasso A,Prasad N,Nozza P,Davies SE,Burroughs AK,Watkinson A,Dhillon AP

更新日期：2003-01-01 00:00:00

abstract：:Myoepithelioma is a rare neoplasm of the salivary glands which is now recognized as an individual entity in the revised WHO classification. In this study, eleven benign tumours are presented. Most patients gave a history of a slowly enlarging mass, which was cured by surgical excision. However, one case recurred sever...

journal_title：Histopathology

authors： Simpson RH,Jones H,Beasley P

更新日期：1995-07-01 00:00:00

abstract：:The morphology, phenotype, genotype and clinical behaviour of four cases of mantle cell lymphoma (centrocytic lymphoma) presenting primarily in mucosa (two gastric, one in large bowel and one tonsillar) are reviewed. Their relationship with the broader group of mantle cell and mucosa-associated lymphoid tissue (MALT) ...

journal_title：Histopathology

authors： Fraga M,Lloret E,Sanchez-Verde L,Orradre JL,Campo E,Bosch F,Piris MA

更新日期：1995-05-01 00:00:00

abstract：AIMS:Equilibrative nucleoside transporter 1 (ENT1) is the major transporter of the chemotherapeutic drug gemcitabine, the current therapy for advanced gallbladder cancer (GBC). ENT1 expression has been proposed as a predictive marker for gemcitabine-treated pancreatic cancer patients. The aim of study was to explore th...

journal_title：Histopathology

authors： Espinoza JA,García P,Bizama C,Leal JL,Riquelme I,Weber H,Macanas P,Aguayo G,Viñuela E,Roa JC,Nervi B

更新日期：2016-04-01 00:00:00

abstract：AIMS:We evaluated polymerase chain reaction (PCR) amplification of specific immunoglobulin heavy chain (IgH) gene rearrangements as a means of demonstrating monoclonality during follow-up of conservatively treated gastric MALT lymphoma, and compared the reproducibility of PCR on sequential frozen and paraffin-embedded ...

journal_title：Histopathology

authors： Aiello A,Giardini R,Tondini C,Balzarotti M,Diss T,Peng H,Delia D,Pilotti S

更新日期：1999-04-01 00:00:00

abstract：:Acinar carcinoma of the prostate is the third most frequently registered cancer and its incidence is expected to increase as life expectancy increases. Consequently, there have been attempts to introduce possible screening programmes for early detection of prostatic carcinoma. In this context the histopathologist has ...

journal_title：Histopathology

authors： Parkinson MC

更新日期：1995-10-01 00:00:00

abstract：AIMS:Patients with aggressive CD8+ cutaneous T-cell lymphomas (CTCLs) progress rapidly and respond poorly to therapy. Confounding treatment planning, there is clinicopathological overlap between aggressive CD8+ CTCLs and other lymphoproliferative disorders (LPDs). Hence, improved diagnostic methods and therapeutic opti...

journal_title：Histopathology

authors： Geller S,Hollmann TJ,Horwitz SM,Myskowski PL,Pulitzer M

更新日期：2020-01-01 00:00:00

abstract：:The immunohistochemistry of the cell population of the human spleen was studied. As controls, a strictly defined group of five specimens were used. This study stresses the need for the utmost care in this selection procedure. Using enzyme- and immuno-histochemistry the lymphocyte subpopulations were studied as to thei...

journal_title：Histopathology

authors： van Krieken JH,te Velde J

更新日期：1986-03-01 00:00:00

abstract：AIMS:Multidrug resistance (MDR) is a major obstacle in the treatment of lymphoma. The expression of MDR-1 mRNA and P-glycoprotein (MDR-1/P-gp) has been linked to MDR. We aimed to investigate the expression of MDR-1/P-gp in B-cell lymphoma. METHODS AND RESULTS:Samples at diagnosis and relapse from 10 patients with B-ce...

journal_title：Histopathology

authors： Liu Q,Ohshima K,Kikuchi M

更新日期：2001-03-01 00:00:00

abstract：AIMS:To evaluate concordance, upgrades and downgrades from biopsy to prostatectomy, and associated clincopathological parameters, using the recently proposed Gleason grade groups/International Society of Urologic Pathology (ISUP) grades. METHODS AND RESULTS:We evaluated 2529 patients who underwent biopsy and prostatec...

journal_title：Histopathology

authors： Athanazio D,Gotto G,Shea-Budgell M,Yilmaz A,Trpkov K

更新日期：2017-06-01 00:00:00

abstract：AIMS:To investigate the prognostic significance of chromosomal alterations in colorectal cancer patients. Histopathological tumour classification is still considered to be the gold standard for the characterization of solid tumours. However, it is well known that such established parameters do not satisfactorily predic...

journal_title：Histopathology

authors： Knösel T,Schlüns K,Stein U,Schwabe H,Schlag PM,Dietel M,Petersen I

更新日期：2003-10-01 00:00:00

abstract：AIMS:To document the clinical, light microscopic, immunohistochemical and ultrastructural features of four cases of extra-orbital giant cell angiofibromas. METHODS AND RESULTS:Sections of formalin-fixed paraffin-embedded specimens were studied by haematoxylin and eosin, reticulin and immunohistochemical stains. Electr...

journal_title：Histopathology

authors： Thomas R,Banerjee SS,Eyden BP,Shanks JH,Bisset DL,Hunt R,Byers RJ,Oogarah P,Harris M

更新日期：2001-10-01 00:00:00

abstract：:Four cases of primary leiomyosarcoma of bone are presented. The histology of this rare tumour has been studied with a panel of monoclonal antibodies to the intermediate filaments desmin and vimentin, and to other markers including smooth muscle actin, myosin, alpha 1-antitrypsin, alpha 1-antichymotrypsin, lysozyme, S-...

journal_title：Histopathology

authors： Young MP,Freemont AJ

更新日期：1991-09-01 00:00:00

abstract：:The clinical and pathological features of six cases of a hitherto undescribed lesion of the breast are reported for which the term 'microglandular adenosis' has been proposed. This is characterized by a proliferation of small uniform glands lined by epithelial cells without apparent myoepithelial cells and with usuall...

journal_title：Histopathology

authors： Clement PB,Azzopardi JG

更新日期：1983-03-01 00:00:00

abstract：AIMS:To investigate the role of BNIP3, a 19-kDa interacting protein of the Bcl-2 family, alongside Bcl-2 in follicular lymphoma in comparison with reactive lymphoid hyperplasia. The results were compared with those from p53 and caspase-3 (apoptotic markers) and Ki67 (proliferation marker). METHODS AND RESULTS:Immunohi...

journal_title：Histopathology

authors： Sington J,Giatromanolaki A,Campo L,Turley H,Pezzella F,Gatter KC

更新日期：2007-04-01 00:00:00

abstract：AIMS:Sessile serrated adenoma/polyp (SSA/P) is regarded as a genetically homogeneous entity, with most lesions harbouring the BRAF V600E mutation. The present study aimed to reappraise the genetic heterogeneity of SSA/Ps and its clinicopathological significance. METHODS AND RESULTS:We performed next-generation sequenc...

journal_title：Histopathology

authors： Cho H,Hashimoto T,Yoshida H,Taniguchi H,Ogawa R,Mori T,Hiraoka N,Saito Y,Sekine S

更新日期：2018-10-01 00:00:00

abstract：AIMS:In some cases distinction between chromophobe renal cell carcinoma (CRCC), oncocytoma and clear cell (conventional) renal cell carcinoma (eosinophilic variant) using routine light microscopy remains problematic. The present study investigates the level of agreement in the diagnosis of CRCC, as well as the histolog...

journal_title：Histopathology

authors： Abrahams NA,MacLennan GT,Khoury JD,Ormsby AH,Tamboli P,Doglioni C,Schumacher B,Tickoo SK

更新日期：2004-12-01 00:00:00

abstract：:Recently, there has been intense interest in the study of gastrointestinal stromal tumour (GIST); one might call it a virtual GIST revolution. This is due largely to the realization that most GISTs express KIT and harbour activating c-KIT (KIT) or platelet-derived growth factor receptor-alpha (PDGFRA) receptor tyrosin...

journal_title：Histopathology

authors： Rubin BP

更新日期：2006-01-01 00:00:00

abstract：AIMS:The Notch signalling pathway is involved in normal development as well as tumorigenesis. However, it is unclear whether Notch activation is related to diverse clinicopathological factors in papillary thyroid carcinoma (PTC). METHODS AND RESULTS:We examined the relationship between clinicopathological factors and ...

journal_title：Histopathology

authors： Jung CW,Kong JS,Seol H,Park S,Koh JS,Lee SS,Kim MJ,Choi IJ,Myung JK

更新日期：2017-01-01 00:00:00

abstract：:Tylosis is an autosomal dominant inherited defect of keratinization, associated in two Liverpool families with a high risk of developing oesophageal squamous carcinoma. In 29 individuals, followed by regular endoscopy and biopsy, we have noted several morphological abnormalities of the epithelium in this pre-cancerous...

journal_title：Histopathology

authors： Ashworth MT,Nash JR,Ellis A,Day DW

更新日期：1991-10-01 00:00:00

abstract：:Analgesic nephropathy is known to have a high incidence in Australia where, following the experience in Scandinavia, reports have been published for some time recording the association between analgesic nephropathy and urothelial malignancies. The morbid anatomical features of analgesic nephropathy are now sufficientl...

journal_title：Histopathology

authors： Lomax-Smith J,Seymour AE

更新日期：1980-05-01 00:00:00