Differences in genetic instability and cellular phenotype among Barrett's, cardiac, and gastric intestinal metaplasia in a Japanese population with Helicobacter pylori.

abstract：:The clinical and pathological features of three adnexal tumours of probable Wolffian origin are reported. One case was an incidental finding in a patient who died from ovarian carcinoma; in the other two cases the patients presented with lower abdominal pain. The three tumours were well-circumscribed, solid masses ari...

journal_title：Histopathology

authors： Rahilly MA,Williams AR,Krausz T,al Nafussi A

更新日期：1995-01-01 00:00:00

abstract：:Thirty-two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries ...

journal_title：Histopathology

authors： Miller N,Bédard YC,Cooter NB,Shaul DL

更新日期：1986-07-01 00:00:00

abstract：:Two series of cutaneous malignant melanoma (CMM), one from a low incidence area (the Oxford Region) and one from a high incidence area (Western Australia), were compared by one pathologist using the same histological criteria. The findings included similarities in the distributions of histogenetic type of CMM, predomi...

journal_title：Histopathology

authors： Heenan PJ,Holman CD

更新日期：1982-11-01 00:00:00

abstract：AIMS:An increased risk of adenocarcinoma of the oesophagus has been demonstrated in patients with long segments of Barrett's mucosa. The risk of cancer associated with short segments of metaplasia of the oesophagogastric junction is not known. METHODS AND RESULTS:We report a case of early adenocarcinoma of the oesopha...

journal_title：Histopathology

authors： Santacroce CM,Fléjou JF

更新日期：1997-07-01 00:00:00

abstract：AIMS:SMAD4 acts as a tumour suppressor, and the loss of SMAD4 is associated with poor prognosis in colorectal cancer (CRC) patients. Although next-generation sequencing (NGS) enabled us to detect numerous genetic alterations in a single assay, the clinical significance of SMAD4 alteration detected with NGS has not been...

journal_title：Histopathology

authors： Oyanagi H,Shimada Y,Nagahashi M,Ichikawa H,Tajima Y,Abe K,Nakano M,Kameyama H,Takii Y,Kawasaki T,Homma KI,Ling Y,Okuda S,Takabe K,Wakai T

更新日期：2019-05-01 00:00:00

abstract：AIMS:To assess cytokeratin (CK) and thyroid transcription factor (TTF)-1 expression in primary epithelial lung tumours by comparison with non-pulmonary carcinomas and to correlate it with their histological type and grade. METHODS AND RESULTS:Immunohistochemistry using antibodies against CKs 5/6, 7, 19, 20 and TTF-1 w...

journal_title：Histopathology

authors： Jerome Marson V,Mazieres J,Groussard O,Garcia O,Berjaud J,Dahan M,Carles P,Daste G

更新日期：2004-08-01 00:00:00

abstract：AIMS:To look for FOXL2 mutation in rare ovarian epithelial lesions showing stromal components with morphological features of adult granulosa cell tumour (AGCT). METHODS AND RESULTS:We report the 402C→G FOXL2 mutation status in five epithelial ovarian lesions in women aged 45-77 years showing stromal proliferations tha...

journal_title：Histopathology

authors： Singh N,Gilks CB,Huntsman DG,Smith JH,Coutts M,Ganesan R,McCluggage WG

更新日期：2014-04-01 00:00:00

abstract：AIMS:The 2009 International Society of Urological Pathology consensus conference recommended reporting the extent of extraprostatic extension (EPE) for the prediction of outcome in prostate cancer. Our aim was to stratify EPE into prognostic groups. METHODS AND RESULTS:We reviewed 1051 radical prostatectomy (RP) speci...

journal_title：Histopathology

authors： Danneman D,Wiklund F,Wiklund NP,Egevad L

更新日期：2013-10-01 00:00:00

abstract：AIMS:p16, a tumour suppressor gene located at 9p21 chromosome and involved in cell cycle regulation, is often inactivated in lung carcinoma. Inactivation is also supported by the loss of p16 protein, a strong inhibitor of cyclin-dependent kinase (CDK) 4 and 6. The aim of this study was to examine alterations of p16 bot...

journal_title：Histopathology

authors： Dessy E,Rossi E,Berenzi A,Tironi A,Benetti A,Grigolato P

更新日期：2008-03-01 00:00:00

abstract：AIMS:We sought to delineate and describe three cases of a distinctive mesenchymal neoplasm of the vulva showing adipocytic differentiation and affecting young patients. METHODS AND RESULTS:In three patients between 13 and 38 years of age, the vulvar tumours had well-circumscribed borders and ranged in size from 35 to ...

journal_title：Histopathology

authors： Lae ME,Pereira PF,Keeney GL,Nascimento AG

更新日期：2002-06-01 00:00:00

abstract：:Immunohistochemical studies on renal biopsies from eight patients with various types of glomerulonephritis showed that the interstitial foam cells belonged to the monocyte-macrophage lineage. There was a strong association between hypercholesterolaemia and the presence of renal interstitial foam cells. ...

journal_title：Histopathology

authors： Franco M,Schmitt F,Rejaili WA,Viero RM,Bacchi CE

更新日期：1992-02-01 00:00:00

abstract：:Hairy leukoplakia is a recently described oral mucosal condition seen in immunosuppressed individuals, usually in association with HIV infection, when it is thought to be a sign of decreasing immunocompetence. It probably results from reactivation of infection by Epstein-Barr virus (EBV) and usually presents as bilate...

journal_title：Histopathology

authors： Southam JC,Felix DH,Wray D,Cubie HA

更新日期：1991-07-01 00:00:00

abstract：AIMS:To investigate redox-regulating enzymes that may have a special role in melanoma pathogenesis due to continuous exposure to microenvironment-produced and ultraviolet radiation-induced oxidative stress. METHODS AND RESULTS:We assessed immunohistochemically the expression of antioxidant enzymes peroxiredoxins (Prxs...

journal_title：Histopathology

authors： Hintsala HR,Soini Y,Haapasaari KM,Karihtala P

更新日期：2015-09-01 00:00:00

abstract：:The generic term aggressive B-cell lymphoma includes a variety of entities, each with particular diagnostic and therapeutic issues. To define these entities better and to help confront such issues, a workshop was organized by the European Association of Haematopathology (EAHP) and the Society of Haematology during the...

journal_title：Histopathology

authors： Leoncini L,Delsol G,Gascoyne RD,Harris NL,Pileri SA,Piris MA,Stein H

更新日期：2005-03-01 00:00:00

abstract：AIMS:Endometrial stromal sarcoma (ESS) has traditionally been divided into low and high grade, but the World Health Organization (WHO, 2003) has changed the definition. Since 2003, many studies have used the old criteria, and few have focused on WHO 2003-defined ESS low grade (ESS-LG). The aim of this study was to inve...

journal_title：Histopathology

authors： Feng W,Hua K,Gudlaugsson E,Yu Y,Zhou X,Baak JP

更新日期：2013-04-01 00:00:00

abstract：:Thirty-two cases of mucoepidermoid carcinoma of the salivary glands were studied in order to characterize the expression of simple mucin-type carbohydrate antigens T, Tn and sialosyl-Tn and to evaluate its implication for tumour histogenesis. Monoclonal antibodies of known specificity were used on formalin-fixed, para...

journal_title：Histopathology

authors： Fonseca I,Costa Rosa J,Félix A,Therkildsen MH,Mandel U,Soares J

更新日期：1994-12-01 00:00:00

abstract：AIMS:Neoadjuvant chemotherapy followed by surgery is the standard of care for patients with gastro-oesophageal adenocarcinoma. The aims were to validate the utility of the tumour regression grade (TRG) in patients who have received chemotherapy and to investigate if (i) TRG correlates with tumour downstaging and (ii) T...

journal_title：Histopathology

authors： Fareed KR,Ilyas M,Kaye PV,Soomro IN,Lobo DN,Parsons SL,Madhusudan S

更新日期：2009-10-01 00:00:00

abstract：AIMS:Restrictive allograft syndrome (RAS) and idiopathic pleuroparenchymal fibroelastosis (IPPFE) are two different diseases reported to share the same histology. RAS relates to chronic allograft dysfunction in lung transplantation, with IPPFE being a rare condition in native lungs. Our aim is to compare their histolog...

journal_title：Histopathology

authors： Montero MA,Osadolor T,Khiroya R,Salcedo MT,Robertus JL,Rice A,Nicholson AG,Roman A,Monforte V

更新日期：2017-06-01 00:00:00

abstract：AIMS:To analyse the expression of alphavbeta6, an epithelial integrin involved in wound healing and tumorigenesis, in various human carcinoma types. METHODS AND RESULTS:A new monoclonal antibody to the human beta6 subunit, 5C4, was used to locate alphavbeta6 in 157 cancers of gastroenteropancreatic and 21 of lung orig...

journal_title：Histopathology

authors： Sipos B,Hahn D,Carceller A,Piulats J,Hedderich J,Kalthoff H,Goodman SL,Kosmahl M,Klöppel G

更新日期：2004-09-01 00:00:00

abstract：AIMS:Immune check-point inhibitors are known to cause immune-mediated adverse liver injury, but our knowledge is mainly based on cases treated with ipilimumab or nivolumab. METHODS AND RESULTS:Clinicopathological features of 10 patients with hepatobiliary adverse reactions caused by second-generation drugs, pembrolizu...

journal_title：Histopathology

authors： Zen Y,Chen YY,Jeng YM,Tsai HW,Yeh MM

更新日期：2020-02-01 00:00:00

abstract：AIMS:Primary sclerosing cholangitis (PSC) is characterized histologically by portal inflammation, bile duct injury and regeneration and concentric periductal fibrosis. Although seen commonly in our experience, the significance of histological thickening of the bile duct basement membrane on periodic acid Schiff (PAS)-p...

journal_title：Histopathology

authors： Colling R,Verrill C,Fryer E,Kartsonaki C,Wang LM,Chapman R,Rajabally N,Fleming K

更新日期：2016-05-01 00:00:00

abstract：:An immunohistochemical study of non-small cell lung carcinoma using PC10, a monoclonal antibody against PCNA, was performed on tissues routinely processed with formalin fixation and paraffin embedding. The PCNA labelling index and mitotic index were determined from sections of these tissues. Tumours showed a high mean...

journal_title：Histopathology

authors： Theunissen PH,Leers MP,Bollen EC

更新日期：1992-03-01 00:00:00

abstract：:A case of visceral botryomycosis of the liver in a 50-year-old man is reported. The clinical diagnosis was hepatocellular carcinoma. Pathological examination of the surgically resected specimen demonstrated microabscesses containing gram- positive microorganisms with surrounding fibrosis replacing liver parenchyma. An...

journal_title：Histopathology

authors： Omar T,Cooper K

更新日期：1995-07-01 00:00:00

abstract：AIMS:Segmental atrophy (SA) of the liver is a recently described pseudotumour that can show a broad spectrum of histological changes. The previously described histological differential diagnosis of SA has included cystic disease of the liver, amyloid, cancer-associated elastosis, and epithelioid haemangioendothelioma. ...

journal_title：Histopathology

authors： Findeis-Hosey JJ,Zhou Z,Gonzalez RS

更新日期：2019-12-01 00:00:00

abstract：AIMS:Matrix metalloproteases (MMPs) and their inhibitors (TIMPs) play an essential role in the degradation of stromal connective tissue and basement membrane components. The aim of this study was to determine whether the dynamic analysis of these components can help to predict tumour aggressiveness. METHODS AND RESULT...

journal_title：Histopathology

authors： González LO,González-Reyes S,Marín L,González L,González JM,Lamelas ML,Merino AM,Rodríguez E,Pidal I,del Casar JM,Andicoechea A,Vizoso F

更新日期：2010-12-01 00:00:00

abstract：:Adhesion molecules are considered to have an important role in inflammatory reactions. We investigated the kinetics of ICAM-1 expression on keratinocytes and correlated this with the numbers of lymphocytes expressing LFA-1 in the dermis and epidermis of evolving allergic contact dermatitis reactions. In nickel-sensiti...

journal_title：Histopathology

authors： Garioch JJ,Mackie RM,Campbell I,Forsyth A

更新日期：1991-10-01 00:00:00

abstract：:We report a primary non-Hodgkin's B-cell lymphoma of the urethra in a 78-year-old female. Serum antibodies for Epstein-Barr virus (EBV) were negative, but there was a 40-fold increase in antibodies to EBV-associated nuclear antigen. Using PCR and in situ hybridization techniques, EBV genome was found in the tumour cel...

journal_title：Histopathology

authors： Ohsawa M,Mishima K,Suzuki A,Hagino K,Doi J,Aozasa K

更新日期：1994-06-01 00:00:00

abstract：:This article considers the issues of image manipulation within the context of electronic/digital images. The possibility for such alterations has occurred with the increasing availability of simple and cheap computer software, permitting modification of digitized images as a whole, or in part. The concepts of acceptab...

journal_title：Histopathology

authors： Suvarna SK,Ansary MA

更新日期：2001-11-01 00:00:00

abstract：:Prolongation of ovarian epithelial cancer survival depends on early detection or improved responses to chemotherapy. Gains in either have been modest at best. Understanding the diverse pathogenesis of this disease is critical to early intervention or prevention. This review addresses six important variables, including...

journal_title：Histopathology

authors： Jarboe EA,Folkins AK,Drapkin R,Ince TA,Agoston ES,Crum CP

更新日期：2008-08-01 00:00:00

abstract：:Clinicopathological and immunohistological features of three cases of large cell lymphoma of bone are reported. On histological grounds, all the cases were diagnosed as histiocytic lymphomas (Rappaport) or primary centroblastic lymphomas, polymorphic subtype (Kiel). On immunophenotyping, malignant cells strongly react...

journal_title：Histopathology

authors： Falini B,Binazzi R,Pileri S,Mori A,Bertoni F,Canino S,Fagioli M,Minelli O,Ciani C,Pellicioli P

更新日期：1988-02-01 00:00:00