Abstract:
PURPOSE OF REVIEW:The objective of this article is to provide an updated review of the economic burden of chronic rhinosinusitis (CRS) and discuss how both medical and surgical interventions impact direct and indirect costs related to CRS. By understanding the economics of CRS, clinicians may improve the patient-centeredness of their care and help distinguish between low and high value interventions. RECENT FINDINGS:Direct costs related to CRS are primarily driven by outpatient physician visits, prescription medical therapy, and endoscopic sinus surgery (ESS). CRS produces large indirect costs and these costs often vary based on the severity of the patients CRS-specific QoL impairment. The overall direct cost related to CRS is estimated to range between $10 and $13 billion per year in the USA. The overall indirect cost related to CRS-related losses in work productivity is estimated to be in excess of $20 billion per year. In the appropriate patients with refractory CRS, ESS provides significant reductions in both direct and indirect costs; however, continued medical therapy alone may be a high value intervention in select patients who have lower severity in their baseline QoL and work productivity.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Rudmik Ldoi
10.1007/s11882-017-0690-5subject
Has Abstractpub_date
2017-04-01 00:00:00pages
20issue
4eissn
1529-7322issn
1534-6315pii
10.1007/s11882-017-0690-5journal_volume
17pub_type
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-018-0773-y
更新日期:2018-02-22 00:00:00
abstract::Exposure to airborne pollen, fungal allergens, and dust mite allergens is associated with the development of allergic rhinitis. Biologic function of allergens is considered to be a key determinant for allergenicity, and many clinically important allergens have been shown to possess enzymatic activity. It is proposed t...
journal_title:Current allergy and asthma reports
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abstract::Vaccines have had a tremendous impact on public health by reducing morbidity and mortality from a variety of virulent pathogens. However, unintended side effects continue to pose a potential risk that may outweigh the vaccine's protective attributes. In this review, we discuss recent articles and controversies pertain...
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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abstract::Research evidence supports a causative relationship between indoor allergen exposure and the development of asthma. Epidemiologic studies demonstrate that exposure to indoor allergens, particularly house-dust mites and cockroaches and, to a lesser extent, animal allergens and mold, is a risk factor for the development...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-003-0023-8
更新日期:2003-03-01 00:00:00
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journal_title:Current allergy and asthma reports
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2002-09-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0391-7
更新日期:2013-12-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-016-0630-9
更新日期:2016-07-01 00:00:00
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更新日期:2019-03-26 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2005-01-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-015-0522-4
更新日期:2015-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0377-5
更新日期:2013-12-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe inherited and acquired genetic variants and clinical entities associated with increased basal serum tryptase (BST), distinguish these levels from those which acutely rise due to mast cell activation, and finally to characterize the association between chronically elevated basal serum trypt...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0887-x
更新日期:2019-11-27 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-002-0005-2
更新日期:2002-03-01 00:00:00
abstract::The pathology of atopic dermatitis is orchestrated on the cellular level by several different cell types in the characteristic skin lesions. In such lesions, histamine as a mediator of many biological functions is also present in high concentrations. Most of the cells involved in the inflammatory responses express the...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-010-0162-7
更新日期:2011-02-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-0902-2
更新日期:2020-03-06 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-006-0061-0
更新日期:2006-07-01 00:00:00
abstract::Otitis media is one of the most common childhood infections leading to doctor's visits and a leading cause of antibiotic prescriptions in children. Twin and family studies have confirmed that the predisposition of developing a bacterial middle ear infection is genetically determined. Several case-control studies have ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-012-0292-1
更新日期:2012-12-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0673-6
更新日期:2017-01-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2013-02-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-0896-9
更新日期:2020-01-10 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-005-0083-z
更新日期:2005-03-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-014-0444-6
更新日期:2014-06-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-014-0468-y
更新日期:2014-10-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2016-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2007-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11882-018-0762-1
更新日期:2018-02-16 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-001-0009-3
更新日期:2001-05-01 00:00:00