Abstract:
:Vaccines have had a tremendous impact on public health by reducing morbidity and mortality from a variety of virulent pathogens. However, unintended side effects continue to pose a potential risk that may outweigh the vaccine's protective attributes. In this review, we discuss recent articles and controversies pertaining to vaccine-associated adverse events. Included in the discussion are influenza, hepatitis B, measles-mumps-rubella, diphtheria-tetanus-pertussis, polio, Haemophilus influenzae type b, and rotavirus vaccines. The importance and contribution of vaccine constituents (such as thimerosal) to side effects is also reviewed.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Song BJ,Katial RKdoi
10.1007/s11882-004-0010-8keywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
447-53issue
6eissn
1529-7322issn
1534-6315journal_volume
4pub_type
杂志文章,评审abstract::Exposure to airborne pollen, fungal allergens, and dust mite allergens is associated with the development of allergic rhinitis. Biologic function of allergens is considered to be a key determinant for allergenicity, and many clinically important allergens have been shown to possess enzymatic activity. It is proposed t...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-005-0041-9
更新日期:2005-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Progestogen hypersensitivity (PH) is a rare disorder which usually occurs in women of childbearing age with symptoms ranging from urticaria with or without angioedema, multiple organ involvement consistent with allergic anaphylaxis, to a spectrum of other non-evanescent skin eruptions. In this review,...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-018-0758-x
更新日期:2018-01-19 00:00:00
abstract::Until recently, idiopathic pulmonary fibrosis (IPF) has been a devastating and generally fatal disease with no effective therapeutic. New developments in understanding the biology of the disease include a growing consensus that the lesions are mainly composed of cells that originated from resident fibroblasts. New dev...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0377-5
更新日期:2013-12-01 00:00:00
abstract::Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the upper airways of which two major phenotypes exist, CRS without nasal polyps (CRSsNP) and CRS with nasal polyps (CRSwNP). Some patients with CRS have suboptimal response to current guideline treatments. These patients remain severe and uncontrolled b...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-015-0520-6
更新日期:2015-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The objective of this article is to provide an updated review of the economic burden of chronic rhinosinusitis (CRS) and discuss how both medical and surgical interventions impact direct and indirect costs related to CRS. By understanding the economics of CRS, clinicians may improve the patient-center...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0690-5
更新日期:2017-04-01 00:00:00
abstract::Asthma and chronic obstructive pulmonary disease (COPD) have traditionally been viewed as distinct clinical entities. Recently, however, much attention has been focused on patients with overlapping features of both asthma and COPD: those with asthma COPD overlap syndrome (ACOS). Although no universal definition criter...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-014-0509-6
更新日期:2015-03-01 00:00:00
abstract::The role of distinct CD4(+) T-cell populations in regulating the nature and strength of immune responses is well documented and in the past has principally focused on the cross-regulation of T-helper type 1 (Th1) and Th2 cells, which secrete interferon-gamma and interleukin-4, respectively. However, the identification...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-009-0078-2
更新日期:2010-01-01 00:00:00
abstract:PURPOSE OF REVIEW:An update on new therapies currently approved or potentially useful in the future for the management of patients suffering moderate-to-severe atopic dermatitis. RECENT FINDINGS:New pathogenic mechanisms involved in atopic dermatitis have permitted to propose novel therapeutic approaches devised to co...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0849-3
更新日期:2019-02-28 00:00:00
abstract::The environment is a major contributor to allergic disease, and great effort is being expended to identify the chemical pollutants and allergens that make a significant impact. Exposure to high levels of ozone, sulfur dioxide, nitrogen dioxide, and diesel exhaust particles is known to reduce lung function. Studies con...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-001-0059-6
更新日期:2001-11-01 00:00:00
abstract::Although eustachian tube dysfunction and bacterial infection have been shown to cause otitis media with effusion (OME), other etiologies are possible. One of the most common medical conditions in children is obesity, which can have effects throughout the body. Little is known, however, about the relationship between o...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-009-0069-3
更新日期:2009-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to describe the process of administering a telemedicine program including reviewing telemedicine guidelines; discussing licensing, credentialing, and privileging of providers; outlining scheduling and recruitment of patients; and measuring outcomes of a telemedicine progr...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-018-0812-8
更新日期:2018-09-15 00:00:00
abstract::Asthma is an episodic respiratory syndrome caused by several pathogenic processes. This recurrent syndrome is associated with an accelerated decline in lung function and increase in airway obstruction over time. The reduced lung function is a consequence of tissue restructuring of all the components of the airway wall...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0056-0
更新日期:2008-07-01 00:00:00
abstract::Atopic dermatitis is a chronic inflammatory skin disease that causes significant morbidity in affected individuals. It is characterized by dysregulated immune responses that consist of an increased systemic Th2 response and a combination of Th2 and Th1 responses in the skin lesions. In this article, we review factors ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-996-0008-5
更新日期:2006-09-01 00:00:00
abstract::The role of fungi in chronic rhinosinusitis (CRS) is not clear. Fungi can be detected in the nose and paranasal sinuses of virtually all CRS patients; however, they also appear to be present in healthy controls. Various theories attempt to explain the mechanisms by which fungi can exert an effect on sinus mucosa in su...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-009-0017-2
更新日期:2009-03-01 00:00:00
abstract::Multiple sclerosis (MS) is the most common cause of chronic neurologic disability in young people. Genetic susceptibility and unidentified environmental triggers appear to be necessary in order to result in disease. MS is an extraordinarily complex trait with evidence of heterogeneity at clinical, pathologic, and ther...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-007-0042-y
更新日期:2007-07-01 00:00:00
abstract::Weeds represent a heterogeneous group of plants, usually defined by no commercial or aesthetic value. Important allergenic weeds belong to the plant families Asteraceae, Amaranthaceae, Urticaceae, Euphorbiaceae, and Plantaginaceae. Major allergens from ragweed, mugwort, feverfew, pellitory, goosefoot, Russian thistle,...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-004-0090-5
更新日期:2004-09-01 00:00:00
abstract::Respiratory viruses appear to play a central role in asthma pathogenesis. In addition to a major role in triggering asthma exacerbations, viral infections early in life may play a role in disease development. Although defensins were initially identified as antimicrobial peptides, recent studies have demonstrated that ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-006-0015-6
更新日期:2006-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Food allergy is increasing in prevalence, and management focuses on strict avoidance of known allergens and appropriately treating reactions. Any reaction has the potential to result in anaphylaxis, which can be fatal. Children spend a significant amount of time in the childcare or school setting, and...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00933-5
更新日期:2020-06-06 00:00:00
abstract:PURPOSE OF REVIEW:Told from the viewpoint of rheumatologists, this review tells the story of hydroxychloroquine and its swift ascent to become a household name as a therapeutic strategy against the novel SARS-CoV-2 virus. This review describes the history, mechanisms, pharmacokinetics, therapeutic applications, and saf...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00983-9
更新日期:2021-01-21 00:00:00
abstract::The present review aims to identify and summarize epidemiologic investigations published during 2011 on the environmental risk factors for asthma. Potentially eligible papers were identified by a MEDLINE search. In total, 1,130 items were retrieved. Based on a broad definition of environment, the following topics were...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-012-0254-7
更新日期:2012-06-01 00:00:00
abstract::T cells are major protagonists of immune-mediated adverse drug eruptions. Immunohistochemical observation as well as isolation and functional characterization of T cells infiltrating the affected tissues provided new insights into the pathomechanisms of the diverse clinical manifestations of drug hypersensitivity, and...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-006-0005-8
更新日期:2006-02-01 00:00:00
abstract::The pathology of atopic dermatitis is orchestrated on the cellular level by several different cell types in the characteristic skin lesions. In such lesions, histamine as a mediator of many biological functions is also present in high concentrations. Most of the cells involved in the inflammatory responses express the...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-010-0162-7
更新日期:2011-02-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to update the information available on the prevalence, clinical picture, diagnostic methods, and treatment of urticarias induced by external physical stimuli. RECENT FINDINGS:Physical urticarias are present in up to 5% of the general population, and in 10 to 50% of patients with chro...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0722-1
更新日期:2017-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Focusing on the strict relationship between house dust mites and crustaceans from the allergenic point of view. RECENT FINDINGS:The well-known tropomyosin was considered for years as the cross-reacting allergen between shrimp and house dust mites. In the last few years, several allergens not only in ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-0902-2
更新日期:2020-03-06 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to provide an overview of diagnostic testing in primary immunodeficiency and immune dysregulatory disorders (PIDDs), particularly focusing on flow cytometry and genetic techniques, utilizing specific examples of PIDDs. RECENT FINDINGS:Flow cytometry remains a vital tool ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-018-0770-1
更新日期:2018-02-22 00:00:00
abstract:PURPOSE OF REVIEW:Food allergy is a growing health problem worldwide that impacts millions of individuals. Current treatment options are limited and strict dietary avoidance remains the standard of care. Immunotherapy using whole, native allergens is under active clinical investigation but harbors the risk of severe si...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0846-6
更新日期:2019-02-22 00:00:00
abstract::Aspirin-exacerbated respiratory disease (AERD) is an acquired disease characterized by chronic eosinophilic airway inflammation with underlying dysregulation of arachidonic acid metabolism. The purpose of this paper is to review the latest developments in our understanding of the underlying pathophysiology including t...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0673-6
更新日期:2017-01-01 00:00:00
abstract::Research evidence supports a causative relationship between indoor allergen exposure and the development of asthma. Epidemiologic studies demonstrate that exposure to indoor allergens, particularly house-dust mites and cockroaches and, to a lesser extent, animal allergens and mold, is a risk factor for the development...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-003-0023-8
更新日期:2003-03-01 00:00:00
abstract::Major progress has been made during the past few years in developing a better understanding of the genetic basis of asthma, which has led to the identification of several chromosomal regions and loci showing linkage to and association with asthma and asthma-related phenotypes. Recent positional cloning approaches have...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-006-0048-x
更新日期:2006-03-01 00:00:00
abstract::Urticaria can present acutely and be self-limiting or become chronic and persist for weeks, months, or years. In either case, the condition may have a significant impact on the patient's quality of life. Two major consensus groups, the EAACI/WAO and the AAAAI/ACAAI Joint Task Force, have written guidelines on the diag...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-015-0535-z
更新日期:2015-06-01 00:00:00