Abstract:
:The present review aims to identify and summarize epidemiologic investigations published during 2011 on the environmental risk factors for asthma. Potentially eligible papers were identified by a MEDLINE search. In total, 1,130 items were retrieved. Based on a broad definition of environment, the following topics were included: obesity, diet, vitamin D, air pollution, farming environment, and social factors. Some of the more relevant contributions included evidence that 1) obesity precedes asthma, 2) fruit consumption is longitudinally associated with a lower risk of asthma and atopy, 3) a comprehensive statewide smoking ban was followed by a reduction in hospital admissions for asthma, 4) asthma is one of the diseases showing the largest burdens due to environmental tobacco smoke, 5) traffic-related urban air pollution is associated with bronchial inflammation as measured by fractional exhaled nitric oxide and uncontrolled asthma, 6) aeroallergens and desert dust may contribute to the short-term effects of air pollution and asthma, and 7) maternal exposure to air pollution before and during pregnancy may alter the immune competence in offspring.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Antó JMdoi
10.1007/s11882-012-0254-7subject
Has Abstractpub_date
2012-06-01 00:00:00pages
192-200issue
3eissn
1529-7322issn
1534-6315journal_volume
12pub_type
杂志文章,评审abstract::Many fungi are capable of causing IgE-mediated hypersensitivity in humans. However, the most predominant fungi implicated in allergy belong to the genera Aspergillus, Alternaria, Cladosporium, and Penicillium. Pure and relevant allergens are essential for diagnosis as well as for understanding the immunopathogenesis o...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-003-0078-6
更新日期:2003-09-01 00:00:00
abstract::Adverse reactions to contrast material are a concern because iodinated contrast materials are commonly used drugs. The risk for adverse reaction is 4% to 12% with ionic contrast materials and 1% to 3% with nonionic contrast materials. The risk for severe adverse reaction is 0.16% with ionic contrast materials and 0.03...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-005-0051-7
更新日期:2005-01-01 00:00:00
abstract::Asthma is an increasingly prevalent disease, particularly in industrialized countries. With modern treatment, many patients can expect good asthma control; however, a significant minority continue to have excessive symptoms. Bronchial thermoplasty is a novel approach to treating asthma in which the hypertrophied airwa...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-009-0013-6
更新日期:2009-01-01 00:00:00
abstract::The environment is a major contributor to allergic disease, and great effort is being expended to identify the chemical pollutants and allergens that make a significant impact. Exposure to high levels of ozone, sulfur dioxide, nitrogen dioxide, and diesel exhaust particles is known to reduce lung function. Studies con...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-001-0059-6
更新日期:2001-11-01 00:00:00
abstract::Research evidence supports a causative relationship between indoor allergen exposure and the development of asthma. Epidemiologic studies demonstrate that exposure to indoor allergens, particularly house-dust mites and cockroaches and, to a lesser extent, animal allergens and mold, is a risk factor for the development...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-003-0023-8
更新日期:2003-03-01 00:00:00
abstract:PURPOSE OF REVIESW:Local respiratory allergy (LRA) is an eosinophilic phenotype of chronic airway disease. Three entities have been described within the LRA spectrum: local allergic rhinitis (LAR) and local allergic asthma (LAA) in non-atopic patients, and dual allergic rhinitis (DAR) in atopic patients (coexistence of...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00920-w
更新日期:2020-05-19 00:00:00
abstract:PURPOSE OF REVIEW:B cell disorders result in decreased levels or function of immunoglobulins in an individual. Genetic mutations have been reported in a variety of B cell disorders. This review, in follow-up to a previous review, describes some rare B cell disorders as well as their known underlying genetic etiologies....
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00963-z
更新日期:2020-08-21 00:00:00
abstract:PURPOSE OF REVIEW:The objective of this article is to provide an updated review of the economic burden of chronic rhinosinusitis (CRS) and discuss how both medical and surgical interventions impact direct and indirect costs related to CRS. By understanding the economics of CRS, clinicians may improve the patient-center...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0690-5
更新日期:2017-04-01 00:00:00
abstract::The buildup of greenhouse gases in the atmosphere has resulted in global climate change that is having a significant effect on many allergenic plants through increases in plant productivity and pollen allergenicity and shifts in plant phenology. Based on experimental studies, increased atmospheric levels of carbon dio...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0081-z
更新日期:2008-09-01 00:00:00
abstract::Asthma is an episodic respiratory syndrome caused by several pathogenic processes. This recurrent syndrome is associated with an accelerated decline in lung function and increase in airway obstruction over time. The reduced lung function is a consequence of tissue restructuring of all the components of the airway wall...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0056-0
更新日期:2008-07-01 00:00:00
abstract::Since rhinosinusitis is an inflammatory disease, cytokines as key regulators of inflammation play a central role in its pathophysiology. In acute rhinosinusitis, several proinflammatory cytokines of different types have been identified. Initial information about the involvement of the inflammasome in rhinosinusitis ha...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-015-0583-4
更新日期:2016-01-01 00:00:00
abstract::Glucocorticoid insensitivity presents a profound management problem in patients with asthma because conventional therapies are not effective. Glucocorticoids, acting through the glucocorticoid receptor (GR), are able to selectively repress inflammatory gene expression by utilizing several distinct mechanisms targeting...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0028-4
更新日期:2008-04-01 00:00:00
abstract::The use of saline nasal irrigation (SNI) in the treatment of nasal and sinus disorders has its roots in the yoga tradition and homeopathic medicine. In recent years, SNI has been increasingly observed as concomitant therapy for acute (ARS) and chronic rhinosinusitis (CRS). Various devices are employed, such as nasal d...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0339-y
更新日期:2013-04-01 00:00:00
abstract::Guillain-Barré syndrome (GBS) is a classic failure of the immune system with a life-threatening attack upon a critical self-component. The active phase of the disease is short, concordant with the latency of a primary adaptive immune response. Triggers for GBS include infection and (rarely) vaccination; cross-reactivi...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-011-0190-y
更新日期:2011-06-01 00:00:00
abstract::Sublingual immunotherapy (SLIT) is a well-established allergen-specific immunotherapy and a safe and effective strategy to reorient inappropriate immune responses in allergic patients. SLIT takes advantage of the tolerogenic environment of the oral mucosa to promote tolerance to the allergen. Several clinical studies ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-014-0473-1
更新日期:2014-11-01 00:00:00
abstract::The physical urticarias are a heterogeneous subgroup of chronic urticarias in which wheals can be reproducibly induced by different specific physical stimuli such as cold, heat, pressure, vibration, or sunlight. Physical urticarias comprise up to 25 % of chronic urticarias and occur more frequently in young adults. Sy...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-012-0269-0
更新日期:2012-08-01 00:00:00
abstract::Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory condition with a multifactorial basis. Infectious triggers of CRS have been proposed, but demonstration remains elusive. Evolving research suggests that abnormal host mucosal immune responses, rather than specific pathogens themselves, may underlie the chron...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-009-0030-5
更新日期:2009-05-01 00:00:00
abstract::The main goals of this review are to help the reader to recognize the common symptoms and signs of exercise-induced asthma and the common objective tests used to confirm or rule out the diagnosis and to understand that different forms and intensities of exercise have different asthmagenicity. The review also aims to h...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0091-x
更新日期:2008-11-01 00:00:00
abstract::DiGeorge syndrome is characterized by conotruncal cardiac defects, hypocalcemia, and a hypoplastic thymus. Many, but not all, patients have a heterozygous deletion of chromosome 22q11.2. In its most severe form, it represents a devastating syndrome with high mortality. Patients with severe immunodeficiency are candida...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-001-0029-z
更新日期:2001-09-01 00:00:00
abstract::Health-related quality of life (HRQL) has become an emerging focus of interest in food allergy. Food allergy is a disease characterized by low mortality and symptoms which only occur during an allergic reaction. However, food-allergic patients continuously need to be alert when eating in order to prevent potentially s...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0391-7
更新日期:2013-12-01 00:00:00
abstract::Expanding knowledge about an interaction of the bacterial colonization with pathogenic and non-pathogenic bacteria and the human immune system leads to speculation on potential effects on health and disease. Recent advances in sequencing technologies and new bioinformatic possibilities now allow investigating the micr...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0382-8
更新日期:2013-10-01 00:00:00
abstract::Given the increased recognition of pediatric allergic contact dermatitis and lack of patch testing consensus in children, we present a minimum basic 20-allergen North American pediatric series, for screening children ages 6-12 with suspected contact allergy. ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-014-0444-6
更新日期:2014-06-01 00:00:00
abstract::Pain and itch sensations are induced by depolarization of distinct populations of unmyelinated type C, and possibly other, neurons. Both sets of neurons and sensations serve critical protective mechanisms that maintain the integrity and patency of the upper airways. When noxious or pruritic stimuli are applied on the ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-003-0042-5
更新日期:2003-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Olfactory functioning disturbances are common following traumatic brain injury (TBI) having a significant impact on quality of life. A spontaneous recovery of the olfactory function over time may occur in TBI patients. Although there is no standard treatment for patients with posttraumatic olfactory l...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00949-x
更新日期:2020-07-09 00:00:00
abstract::Weeds represent a heterogeneous group of plants, usually defined by no commercial or aesthetic value. Important allergenic weeds belong to the plant families Asteraceae, Amaranthaceae, Urticaceae, Euphorbiaceae, and Plantaginaceae. Major allergens from ragweed, mugwort, feverfew, pellitory, goosefoot, Russian thistle,...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-004-0090-5
更新日期:2004-09-01 00:00:00
abstract::Until recently, idiopathic pulmonary fibrosis (IPF) has been a devastating and generally fatal disease with no effective therapeutic. New developments in understanding the biology of the disease include a growing consensus that the lesions are mainly composed of cells that originated from resident fibroblasts. New dev...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0377-5
更新日期:2013-12-01 00:00:00
abstract::Recognition of asthma as a heterogeneous disease revealed different potential molecular targets and urged the development of targeted, customized treatment modalities. Evidence was provided for different inflammatory subsets of asthma and more recently, further refined to T helper (Th)2-high and Th2-low subphenotypes ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-013-0376-6
更新日期:2013-10-01 00:00:00
abstract::Atopic dermatitis (AD) is a complex disease that manifests immunologic abnormalities in the skin. The immunologic changes of AD are characterized by a T helper cell type 2 (Th2)-dominated immune response in its acute phase and a Th1/Th2 mixed immune response in its chronic phase. Although the clinical presentation and...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-005-0069-x
更新日期:2005-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The prevalence of food allergy is increasing. At the current time, there are no approved treatments for food allergy. Major limitations of immunotherapy are long treatment periods (months or years), frequent clinic visits, high costs, increased risk of adverse events during treatment, and lack of dura...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-0897-8
更新日期:2020-01-16 00:00:00
abstract::Respiratory viruses appear to play a central role in asthma pathogenesis. In addition to a major role in triggering asthma exacerbations, viral infections early in life may play a role in disease development. Although defensins were initially identified as antimicrobial peptides, recent studies have demonstrated that ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-006-0015-6
更新日期:2006-02-01 00:00:00