Abstract:
PURPOSE OF REVIEW:The prevalence of food allergy is increasing. At the current time, there are no approved treatments for food allergy. Major limitations of immunotherapy are long treatment periods (months or years), frequent clinic visits, high costs, increased risk of adverse events during treatment, and lack of durability of desensitization. Additionally, it is allergen-specific, and in those allergic to multiple allergens, the length and cost of treatment are further increased. In this review, we summarize recent developments in novel non-allergen-specific treatments for food allergy. RECENT FINDINGS:A number of monoclonal antibodies that block IgE or specific pro-allergenic cytokines or their receptors have shown promise in clinical trials for food allergy. The insight we have gained through the use of one drug for the treatment of an atopic disease is quickly being translated to other atopic diseases, including food allergy. The future for food allergy treatment with biologics looks bright.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Long A,Borro M,Sampath V,Chinthrajah RSdoi
10.1007/s11882-020-0897-8subject
Has Abstractpub_date
2020-01-16 00:00:00pages
3issue
1eissn
1529-7322issn
1534-6315pii
10.1007/s11882-020-0897-8journal_volume
20pub_type
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