Abstract:
:Exposure to airborne pollen, fungal allergens, and dust mite allergens is associated with the development of allergic rhinitis. Biologic function of allergens is considered to be a key determinant for allergenicity, and many clinically important allergens have been shown to possess enzymatic activity. It is proposed that by enabling allergens to breach the integrity of the airway epithelial barrier, proteolytic activity plays an adjuvant pro-allergic role influencing immunogenicity. In this review, current evidence regarding enzymatic activity of aeroallergens is described, and the potential role of aeroallergens in allergic rhinitis is discussed.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Sehgal N,Custovic A,Woodcock Adoi
10.1007/s11882-005-0041-9keywords:
subject
Has Abstractpub_date
2005-05-01 00:00:00pages
221-6issue
3eissn
1529-7322issn
1534-6315journal_volume
5pub_type
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2015-08-01 00:00:00
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更新日期:2003-01-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2018-06-14 00:00:00
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更新日期:2006-07-01 00:00:00