Invited commentary: recommendation for a north american pediatric patch test series.

abstract：:Mast cell activation syndrome (MCAS) can be diagnosed in patients with recurrent, severe symptoms from mast cell (MC)-derived mediators, which are transiently increased in serum and are attenuated by mediator-targeting drugs. When KIT-mutated, clonal MC are detected in these patients, a diagnosis of primary MCAS can b...

journal_title：Current allergy and asthma reports

authors： Bonadonna P,Bonifacio M,Lombardo C,Zanotti R

更新日期：2016-01-01 00:00:00

abstract：:Many fungi are capable of causing IgE-mediated hypersensitivity in humans. However, the most predominant fungi implicated in allergy belong to the genera Aspergillus, Alternaria, Cladosporium, and Penicillium. Pure and relevant allergens are essential for diagnosis as well as for understanding the immunopathogenesis o...

journal_title：Current allergy and asthma reports

authors： Kurup VP

更新日期：2003-09-01 00:00:00

abstract：:Asthma is a chronic inflammatory disease of the airways characterized by structural airway changes, which are known as airway remodeling, including smooth muscle hypertrophy, goblet cell hyperplasia, subepithelial fibrosis, and angiogenesis. Vascular remodeling in asthmatic lungs results from increased angiogenesis, w...

journal_title：Current allergy and asthma reports

authors： Meyer N,Akdis CA

更新日期：2013-02-01 00:00:00

abstract：:Adverse reactions to contrast material are a concern because iodinated contrast materials are commonly used drugs. The risk for adverse reaction is 4% to 12% with ionic contrast materials and 1% to 3% with nonionic contrast materials. The risk for severe adverse reaction is 0.16% with ionic contrast materials and 0.03...

journal_title：Current allergy and asthma reports

authors： Cochran ST

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Agriculture remains a major economic sector globally, and workers experience high rates of chronic inflammatory lung and musculoskeletal diseases. Whereas obstructive pulmonary diseases are known risk factors for bone loss, the underlying relationship between lung inflammation and bone health is not w...

journal_title：Current allergy and asthma reports

authors： Carrington JM,Poole JA

更新日期：2018-02-22 00:00:00

abstract：:Respiratory viruses appear to play a central role in asthma pathogenesis. In addition to a major role in triggering asthma exacerbations, viral infections early in life may play a role in disease development. Although defensins were initially identified as antimicrobial peptides, recent studies have demonstrated that ...

journal_title：Current allergy and asthma reports

authors： Proud D

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been an explosion in the number of published systematic reviews on chronic rhinosinusitis in the last decade. RECENT FINDINGS:While the aim of these reviews in facilitating evidence-based practice is laudable, poor quality reviews may contain significant bias that can mislead a non-discerni...

journal_title：Current allergy and asthma reports

authors： Walker A,Hopkins C

更新日期：2018-02-16 00:00:00

abstract：:Patients with specific food allergies are commonly sensitized to related foods, for example, shrimp with other shellfish and peanut with other legumes. In some instances, this represents a true allergy to the related food, defined as cross-reactivity, while in other instances, it represents a positive skin or IgE test...

journal_title：Current allergy and asthma reports

authors： Kazatsky AM,Wood RA

更新日期：2016-03-01 00:00:00

abstract：:Allergic conjunctivitis (AC) can be divided into the primary form (caused by an allergic reaction occurring primarily in the conjunctivae) and the secondary form (induced by allergic reaction originating primarily in the nasal mucosa, where the released mediators can reach conjunctiva through the lacrimal system, the ...

journal_title：Current allergy and asthma reports

authors： Pelikan Z

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an overview of diagnostic testing in primary immunodeficiency and immune dysregulatory disorders (PIDDs), particularly focusing on flow cytometry and genetic techniques, utilizing specific examples of PIDDs. RECENT FINDINGS:Flow cytometry remains a vital tool ...

journal_title：Current allergy and asthma reports

authors： Richardson AM,Moyer AM,Hasadsri L,Abraham RS

更新日期：2018-02-22 00:00:00

abstract：:Exposure to airborne pollen, fungal allergens, and dust mite allergens is associated with the development of allergic rhinitis. Biologic function of allergens is considered to be a key determinant for allergenicity, and many clinically important allergens have been shown to possess enzymatic activity. It is proposed t...

journal_title：Current allergy and asthma reports

authors： Sehgal N,Custovic A,Woodcock A

更新日期：2005-05-01 00:00:00

abstract：:Asthma affects 5% to 10% of the population of the United States. In asthmatics, oxidative stress occurs not only as a result of inflammation but also from environmental exposure to air pollution. The specific localization of antioxidants in the lung and the adaptive changes during asthma underscore the importance of o...

journal_title：Current allergy and asthma reports

authors： Bowler RP

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aimed to review important hidden causes of anaphylaxis in ingestants, non-ingestants, and uncommon settings. RECENT FINDINGS:Multiple new and elusive causes of anaphylaxis have been described over the past 35 years. Further research is required to identify the epidemiology, pathophysiology...

journal_title：Current allergy and asthma reports

authors： Nanagas VC,Baldwin JL,Karamched KR

更新日期：2017-07-01 00:00:00

abstract：:Recent advances in our understanding of mast cell biology and disease resulted in identification of important differences in expression of mast cell surface antigens in normal and neoplastic mast cells. Most notably, detection of aberrant expression of CD25 and CD2 on the surface of neoplastic mast cells but not on th...

journal_title：Current allergy and asthma reports

authors： Akin C,Valent P,Escribano L

更新日期：2006-07-01 00:00:00

abstract：:Otitis media is currently the most common diagnosis made by clinicians, which has a major impact on managed care. The emergence of resistant bacterial pathogens has caused controversy over the use of antibiotics when acute otitis media (AOM) is diagnosed. All infants with AOM and all older children with severe AOM sho...

journal_title：Current allergy and asthma reports

authors： Gungor A,Bluestone CD

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:B cell disorders result in decreased levels or function of immunoglobulins in an individual. Genetic mutations have been reported in a variety of B cell disorders. This review, in follow-up to a previous review, describes some rare B cell disorders as well as their known underlying genetic etiologies....

journal_title：Current allergy and asthma reports

authors： Griffin DD,Dolen WK

更新日期：2020-08-21 00:00:00

abstract：:Atopic dermatitis is a chronic inflammatory skin disease that causes significant morbidity in affected individuals. It is characterized by dysregulated immune responses that consist of an increased systemic Th2 response and a combination of Th2 and Th1 responses in the skin lesions. In this article, we review factors ...

journal_title：Current allergy and asthma reports

authors： Ong PY,Leung DY

更新日期：2006-09-01 00:00:00

abstract：:Otitis media (OM) imposes significant morbidity on the pediatric age group and a large financial burden on the general population. Because standard medical treatments are not highly efficacious in resolving the accompanying middle ear (ME) inflammation, a goal of current research is OM prevention. Past studies show th...

journal_title：Current allergy and asthma reports

authors： Doyle WJ,Alper CM

更新日期：2003-07-01 00:00:00

abstract：:Specific allergen immunotherapy (SIT) is the only disease-modifying treatment for allergic rhinitis and asthma. Subcutaneous immunotherapy (SCIT) is the only method with a US Food and Drug Administration (FDA)-approved formulation, but safety concerns limit administration to medical facilities. Sublingual immunotherap...

journal_title：Current allergy and asthma reports

authors： Cox L

更新日期：2007-11-01 00:00:00

abstract：:Occupational asthma (OA) is a complex disease that is often hard to diagnose due to difficulties in detecting relevant exposure, along with inherent differences in disease susceptibility. Numerous studies have attempted to identify relevant biological and genetic markers for OA and to devise tools capable of detecting...

journal_title：Current allergy and asthma reports

authors： Hur GY,Park HS

更新日期：2015-01-01 00:00:00

abstract：:In this review, we examine the critical periods of immune development and how these might be modified to prevent food allergy. The relevant dietary intervention studies, roles of microorganisms and their products, and other strategies are critically analyzed. Additionally, we highlight the potential importance of diff...

journal_title：Current allergy and asthma reports

authors： Khakoo A,Lack G

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to provide an update of recent advances in the epidemiology, clinical features and diagnosis, and management of food-induced anaphylaxis (FIA). RECENT FINDINGS:Food allergy prevalence and FIA rates continue to rise, but FIA fatalities are stable. Basophil and mast cell activation tes...

journal_title：Current allergy and asthma reports

authors： Parrish CP,Kim H

更新日期：2018-06-14 00:00:00

abstract：:Orbital myositis is an inflammatory process that primarily involves the extraocular muscles and most commonly affects young adults in the third decade of life, with a female predilection. Clinical characteristics of orbital myositis include orbital and periorbital pain, ocular movement impairment, diplopia, proptosis,...

journal_title：Current allergy and asthma reports

authors： Costa RM,Dumitrascu OM,Gordon LK

更新日期：2009-07-01 00:00:00

abstract：:Mouse allergen has long been recognized as an important cause of occupational allergy and asthma, but only recently has it been implicated in asthma and allergic diseases in community settings. Recent studies have established that mouse allergen is detectable in most US homes, with strikingly high levels in some inner...

journal_title：Current allergy and asthma reports

authors： Matsui EC

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevalence of food allergy is increasing. At the current time, there are no approved treatments for food allergy. Major limitations of immunotherapy are long treatment periods (months or years), frequent clinic visits, high costs, increased risk of adverse events during treatment, and lack of dura...

journal_title：Current allergy and asthma reports

authors： Long A,Borro M,Sampath V,Chinthrajah RS

更新日期：2020-01-16 00:00:00

abstract：PURPOSE OF REVIEW:Told from the viewpoint of rheumatologists, this review tells the story of hydroxychloroquine and its swift ascent to become a household name as a therapeutic strategy against the novel SARS-CoV-2 virus. This review describes the history, mechanisms, pharmacokinetics, therapeutic applications, and saf...

journal_title：Current allergy and asthma reports

authors： Udupa A,Leverenz D,Balevic SJ,Sadun RE,Tarrant TK,Rogers JL

更新日期：2021-01-21 00:00:00

abstract：:Traditionally, symptoms are important patient-oriented outcomes in asthma treatment, and assessment of symptoms is an essential component of assessing asthma control. However, variable airways obstruction, airways hyperresponsiveness and chronic inflammation are key components of the asthma syndrome, and correlations ...

journal_title：Current allergy and asthma reports

authors： Nuijsink M,De Jongste JC,Pijnenburg MW

更新日期：2013-10-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is an inflammatory disorder affecting the nose and paranasal sinuses. Although bacteria have long been implicated as pathogens in most forms of CRS, fungi may be responsible for some forms. Several recent studies demonstrated that, under optimal conditions, fungi can be identified in the n...

journal_title：Current allergy and asthma reports

authors： Ebbens FA,Fokkens WJ

更新日期：2008-04-01 00:00:00

abstract：:Natural oils include mineral oil with emollient, occlusive, and humectant properties and the plant-derived essential, coconut, and other vegetable oils, composed of triglycerides that microbiota lipases hydrolyze into glycerin, a potent humectant, and fatty acids (FAs) with varying physico-chemical properties. Unsatur...

journal_title：Current allergy and asthma reports

authors： Verallo-Rowell VM,Katalbas SS,Pangasinan JP

更新日期：2016-07-01 00:00:00

abstract：PURPOSES OF REVIEW:Th9 cells are recognized as a novel subset of effector T helper cells that preferentially produce IL-9. Here, we provide a current update on the reports related to the function of Th9 cells in allergic inflammatory diseases. RECENT FINDINGS:The effector Th9 cells differentiating from naïve T helper ...

journal_title：Current allergy and asthma reports

authors： Angkasekwinai P

更新日期：2019-03-26 00:00:00