Abstract:
:Allergic conjunctivitis (AC) can be divided into the primary form (caused by an allergic reaction occurring primarily in the conjunctivae) and the secondary form (induced by allergic reaction originating primarily in the nasal mucosa, where the released mediators can reach conjunctiva through the lacrimal system, the blood, the lymphatic network, or the neurogenic network). Patients with primary AC develop an immediate, late, or delayed conjunctival response (CR) during conjunctival provocation tests. Patients with secondary AC develop an immediate, late, or delayed type of secondary CR, induced by the nasal allergic reaction, due to the nasal allergen challenge. Various hypersensitivity mechanisms may be involved in the particular CR types. The secondarily induced AC and CRs can only be confirmed by nasal provocations tests, performed by rhinomanometry combined with recording of conjunctival signs. The existence of the primary and secondarily induced AC has an impact on treatment of this disorder.
journal_name
Curr Allergy Asthma Repjournal_title
Current allergy and asthma reportsauthors
Pelikan Zdoi
10.1007/s11882-010-0119-xsubject
Has Abstractpub_date
2010-07-01 00:00:00pages
295-302issue
4eissn
1529-7322issn
1534-6315journal_volume
10pub_type
杂志文章abstract:PURPOSE OF REVIEW:The adaptive immune response orchestrated by type 2 T helper (Th2) lymphocytes, strictly cooperates with the innate response of group 2 innate lymphoid cells (ILC2), in the protection from helminths infection, as well as in the pathogenesis of allergic disease. The aim of this review is to explore the...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0735-9
更新日期:2017-09-11 00:00:00
abstract::Omalizumab is a recently developed monoclonal anti-IgE antibody. Clinical trials have demonstrated its efficacy in patients with moderate-to-severe and severe or poorly controlled allergic asthma, in patients with seasonal and perennial allergic disease, and in subjects with concomitant asthma and allergic rhinitis. P...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章
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更新日期:2005-03-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-009-0045-y
更新日期:2009-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The prevalence of food allergy is increasing. At the current time, there are no approved treatments for food allergy. Major limitations of immunotherapy are long treatment periods (months or years), frequent clinic visits, high costs, increased risk of adverse events during treatment, and lack of dura...
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pub_type: 杂志文章,评审
doi:10.1007/s11882-020-0897-8
更新日期:2020-01-16 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-014-0444-6
更新日期:2014-06-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
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更新日期:2015-02-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0690-5
更新日期:2017-04-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0056-0
更新日期:2008-07-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0877-z
更新日期:2019-09-10 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章
doi:10.1007/s11882-009-0003-8
更新日期:2009-01-01 00:00:00
abstract::The dynamic expression of various phenotypic markers during B cell development not only defines the particular stage in ontogeny but also provides the necessary growth, differentiation, maturation and survival signals. When a B cell at any given stage becomes cancerous, these cell surface molecules, intracellular sign...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-012-0327-7
更新日期:2013-02-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0860-8
更新日期:2019-03-26 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-015-0583-4
更新日期:2016-01-01 00:00:00
abstract::Asthma is an increasingly prevalent disease, particularly in industrialized countries. With modern treatment, many patients can expect good asthma control; however, a significant minority continue to have excessive symptoms. Bronchial thermoplasty is a novel approach to treating asthma in which the hypertrophied airwa...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-009-0013-6
更新日期:2009-01-01 00:00:00
abstract::Oral food challenges are the gold-standard diagnostic investigation for diagnosing food allergy. They allow a subject to consume an age-appropriate portion of allergenic food under surveillance to assess whether a reproducible immune-mediated adverse response is demonstrated. The specific design of food challenge must...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-015-0549-6
更新日期:2015-08-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-010-0090-6
更新日期:2010-03-01 00:00:00
abstract::Viral rhinitis is a common, morbid, and costly malady, often complicated by otitis media, sinusitis, and asthma. Current therapies are relatively ineffective and aimed at reducing symptoms rather than moderating underlying mechanisms. Nasal elevations of proinflammatory cytokines track symptom expression during viral ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-001-0009-3
更新日期:2001-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-014-0509-6
更新日期:2015-03-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-006-0036-1
更新日期:2006-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe inherited and acquired genetic variants and clinical entities associated with increased basal serum tryptase (BST), distinguish these levels from those which acutely rise due to mast cell activation, and finally to characterize the association between chronically elevated basal serum trypt...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0887-x
更新日期:2019-11-27 00:00:00
abstract::Weeds represent a heterogeneous group of plants, usually defined by no commercial or aesthetic value. Important allergenic weeds belong to the plant families Asteraceae, Amaranthaceae, Urticaceae, Euphorbiaceae, and Plantaginaceae. Major allergens from ragweed, mugwort, feverfew, pellitory, goosefoot, Russian thistle,...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-004-0090-5
更新日期:2004-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Food allergy is increasing in prevalence, and management focuses on strict avoidance of known allergens and appropriately treating reactions. Any reaction has the potential to result in anaphylaxis, which can be fatal. Children spend a significant amount of time in the childcare or school setting, and...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00933-5
更新日期:2020-06-06 00:00:00
abstract::Glucocorticoid insensitivity presents a profound management problem in patients with asthma because conventional therapies are not effective. Glucocorticoids, acting through the glucocorticoid receptor (GR), are able to selectively repress inflammatory gene expression by utilizing several distinct mechanisms targeting...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-008-0028-4
更新日期:2008-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to provide an overview of diagnostic testing in primary immunodeficiency and immune dysregulatory disorders (PIDDs), particularly focusing on flow cytometry and genetic techniques, utilizing specific examples of PIDDs. RECENT FINDINGS:Flow cytometry remains a vital tool ...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-018-0770-1
更新日期:2018-02-22 00:00:00
abstract:PURPOSE OF REVIEW:Antibiotics are commonly used to treat wheezy lower respiratory tract illnesses in preschoolers, although these infections have been traditionally thought to be predominantly of viral origin. Our purpose is to review recent research pertaining to the role of antibiotics in lower respiratory tract illn...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-017-0701-6
更新日期:2017-05-01 00:00:00
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journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-014-0473-1
更新日期:2014-11-01 00:00:00
abstract::Vaccines have had a tremendous impact on public health by reducing morbidity and mortality from a variety of virulent pathogens. However, unintended side effects continue to pose a potential risk that may outweigh the vaccine's protective attributes. In this review, we discuss recent articles and controversies pertain...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-004-0010-8
更新日期:2004-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Olfactory functioning disturbances are common following traumatic brain injury (TBI) having a significant impact on quality of life. A spontaneous recovery of the olfactory function over time may occur in TBI patients. Although there is no standard treatment for patients with posttraumatic olfactory l...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-020-00949-x
更新日期:2020-07-09 00:00:00
abstract:PURPOSE OF REVIEW:This paper offers a comprehensive review of interactive mobile allergy and asthma smartphone applications available within the USA in 2018, with an emphasis on interactive asthma apps. RECENT FINDINGS:Primary care and specialty clinicians interested in introducing digital health apps into their pract...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-019-0840-z
更新日期:2019-02-02 00:00:00
abstract::The pathology of atopic dermatitis is orchestrated on the cellular level by several different cell types in the characteristic skin lesions. In such lesions, histamine as a mediator of many biological functions is also present in high concentrations. Most of the cells involved in the inflammatory responses express the...
journal_title:Current allergy and asthma reports
pub_type: 杂志文章,评审
doi:10.1007/s11882-010-0162-7
更新日期:2011-02-01 00:00:00