Abstract：
:Current clinically accepted technologies for cancer treatment still have limitations which lead to the exploration of new therapeutic methods. Since the past few decades, the hyperthermia treatment has attracted the attention of investigators owing to its strong biological rationales in applying hyperthermia as a cancer treatment modality. Advancement of nanotechnology offers a potential new heating method for hyperthermia by using nanoparticles which is termed as magnetic fluid hyperthermia (MFH). In MFH, superparamagnetic nanoparticles dissipate heat through Néelian and Brownian relaxation in the presence of an alternating magnetic field. The heating power of these particles is dependent on particle properties and treatment settings. A number of pre-clinical and clinical trials were performed to test the feasibility of this novel treatment modality. There are still issues yet to be solved for the successful transition of this technology from bench to bedside. These issues include the planning, execution, monitoring and optimization of treatment. The modeling and simulation play crucial roles in solving some of these issues. Thus, this review paper provides a basic understanding of the fundamental and rationales of hyperthermia and recent development in the modeling and simulation applied to depict the heat generation and transfer phenomena in the MFH.
journal_name
Biomed Eng Onlinejournal_title
Biomedical engineering onlineauthors
Suriyanto,Ng EY,Kumar SDdoi
10.1186/s12938-017-0327-xsubject
Has Abstractpub_date
2017-03-23 00:00:00pages
36issue
1issn
1475-925Xpii
10.1186/s12938-017-0327-xjournal_volume
16pub_type
杂志文章,评审abstract：INTRODUCTION:The method for measuring intraocular pressure using the Corvis tonometer provides a sequence of images of corneal deformation. Deformations of the cornea are recorded using the ultra-high-speed Scheimpflug camera. This paper presents a new and reproducible method of analysis of corneal deformation images t...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-150
更新日期：2014-11-19 00:00:00
abstract：BACKGROUND:Heart rate can be used to prescribe exercise intensity for development and maintenance of cardiorespiratory fitness. The aim of this study was to identify the dynamics of heart rate response during moderate-to-vigorous treadmill exercise and to explore parameter dependencies with respect to time, intensity l...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0112-7
更新日期：2015-12-21 00:00:00
abstract：BACKGROUND:Advances in transcranial electrical stimulation (tES) are hampered by the conventional rubber electrodes manually attached to the head with rubber bands. This procedure limits montages to a few electrodes, is error prone with respect to electrode configurations and is burdensome for participants and operator...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-020-00792-1
更新日期：2020-06-17 00:00:00
abstract：BACKGROUND:This paper proposes a methodology for helping bridge the gap between the complex waveform information frequently available in an intensive care unit and the simple, lumped values favoured for rapid clinical diagnosis and management. This methodology employs a simple waveform contour analysis approach to comp...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-018-0603-4
更新日期：2018-11-20 00:00:00
abstract：INTRODUCTION:This paper shows the influence of a measurement method of features in the diagnosis of Hashimoto's disease. Sensitivity of the algorithm to changes in the parameters of the ROI, namely shift, resizing and rotation, has been presented. The obtained results were also compared to the methods known from the li...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-11-91
更新日期：2012-11-28 00:00:00
abstract：BACKGROUND:The biomechanical simulation of the human respiratory system is expected to be a useful tool for the diagnosis and treatment of respiratory diseases. Because the deformation of the thorax significantly influences airflow in the lungs, we focused on simulating the thorax deformation by introducing contraction...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0132-y
更新日期：2016-02-06 00:00:00
abstract：:Advances in biomaterials and the need for patient-specific bone scaffolds require modern manufacturing approaches in addition to a design strategy. Hybrid materials such as those with functionally graded properties are highly needed in tissue replacement and repair. However, their constituents, proportions, sizes, con...
journal_title：Biomedical engineering online
pub_type： 杂志文章,评审
doi：10.1186/s12938-020-00810-2
更新日期：2020-09-03 00:00:00
abstract：BACKGROUND:Sleep apnea (OSA) is a common sleep disorder characterized by recurring breathing pauses during sleep caused by a blockage of the upper airway (UA). The altered UA structure or function in OSA speakers has led to hypothesize the automatic analysis of speech for OSA assessment. In this paper we critically rev...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0138-5
更新日期：2016-02-20 00:00:00
abstract：BACKGROUND:Good anatomical compatibility is an important aspect in the development of cardiovascular implants. This work analyzes the interaction of the pump unit of an electrically driven pulsatile Total Artificial Heart (TAH) and the mediastinum. For an adequate compliance, both overall dimensions and alignment of in...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-81
更新日期：2013-08-14 00:00:00
abstract：BACKGROUND:It is generally accepted that cartilage adaptation and degeneration are mechanically mediated. Investigating the swelling behaviour of cartilage is important because the stress and strain state of cartilage is associated with the swelling and deformation behaviour. It is well accepted that the swelling of so...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925x-1-8
更新日期：2002-12-19 00:00:00
abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal tumors and usually presented with locally advanced and distant metastasis disease, which prevent curative resection or treatments. In this regard, we considered identifying molecular subtypes associated with clinicopathological factor as progn...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-S2-S5
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Tortuous arteries are often seen in patients with hypertension and atherosclerosis. While the mechanical stress in atherosclerotic plaque under lumen pressure has been studied extensively, the mechanical stability of atherosclerotic arteries and subsequent effect on the plaque stress remain unknown. To this ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-S1-S4
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:In this study, we have examined local non-viral gene delivery, transfection, and therapeutic efficacy of endothelial nitric oxide synthase (eNOS) encoding plasmid DNA administered using coated stents in a rabbit iliac artery restenosis model. METHODS:Lipopolyplexes (LPPs) with eNOS expressing plasmid DNA we...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-9-56
更新日期：2010-09-27 00:00:00
abstract：BACKGROUND:Atherosclerotic plaque progression and rupture are believed to be associated with mechanical stress conditions. In this paper, patient-specific in vivo intravascular ultrasound (IVUS) coronary plaque image data were used to construct computational models with fluid-structure interaction (FSI) and cyclic bend...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-32
更新日期：2014-03-26 00:00:00
abstract：BACKGROUND:Since the first well-known electrocardiogram (ECG) delineator based on Wavelet Transform (WT) presented by Li et al. in 1995, a significant research effort has been devoted to the exploitation of this promising method. Its ability to reliably delineate the major waveform components (mono- or bi-phasic P wave...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-23
更新日期：2011-04-03 00:00:00
abstract：BACKGROUND:Areas with high frequency activity within the atrium are thought to be 'drivers' of the rhythm in patients with atrial fibrillation (AF) and ablation of these areas seems to be an effective therapy in eliminating DF gradient and restoring sinus rhythm. Clinical groups have applied the traditional FFT-based a...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0143-8
更新日期：2016-03-08 00:00:00
abstract：BACKGROUND:One of the recommended treatments for disorders associated with the lower extremity venous insufficiency is the application of external mechanical compression. Compression stockings and elastic bandages are widely used for the purpose of compression therapy and are usually designed to exert a specified value...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0088-3
更新日期：2015-11-05 00:00:00
abstract：BACKGROUND:The bioluminescent enzyme firefly luciferase (Luc) or variants of green fluorescent protein (GFP) in transformed cells can be effectively used to reveal molecular and cellular features of neoplasia in vivo. Tumor cell growth and regression in response to various therapies can be evaluated by using biolumines...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-3-12
更新日期：2004-05-04 00:00:00
abstract：BACKGROUND:For electroporation-based therapies, accurate modeling of the electric field distribution within the target tissue is important for predicting the treatment volume. In response to conventional, unipolar pulses, the electrical impedance of a tissue varies as a function of the local electric field, leading to ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-S3-S3
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:The main problem of tremor is the damage caused to the quality of the life of patients, especially those at more advanced ages. There is not a consensus yet about the origins of this disorder, but it can be examined in the correlations between the biological signs of aging and the tremor characteristics. ME...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-9-29
更新日期：2010-06-22 00:00:00
abstract：BACKGROUND:Frequency selectivity (FS) of the auditory system is established at the level of the cochlea and it is important for the perception of complex sounds. Although direct measurements of cochlear FS require surgical preparation, it can also be estimated with the measurements of otoacoustic emissions or behaviora...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-016-0167-0
更新日期：2016-05-10 00:00:00
abstract：:Radiofrequency ablation is an interventional technique that in recent years has come to be employed in very different medical fields, such as the elimination of cardiac arrhythmias or the destruction of tumors in different locations. In order to investigate and develop new techniques, and also to improve those current...
journal_title：Biomedical engineering online
pub_type： 杂志文章,评审
doi：10.1186/1475-925X-5-24
更新日期：2006-04-18 00:00:00
abstract：BACKGROUND:Reach-grasp movements are motor components commonly affected after stroke and directly related to the independence of these individuals. Evaluations of these activities can be performed using clinical instruments and assessed by detailed and costly kinematic analyses. The aim of this study was to develop an ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-020-0758-7
更新日期：2020-03-04 00:00:00
abstract：BACKGROUND:Intracranial pressure changes during head impact cause brain injuries such as vasogenic edema and cerebral contusion. However, the influence of impulsive pressure on endothelial function has not yet been fully studied in vitro. In this study, we developed a pressure loading device that produced positive and ...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-13-44
更新日期：2014-04-16 00:00:00
abstract：BACKGROUND:A specific problem using the public access defibrillators (PADs) arises at the railway stations. Some countries as Germany, Austria, Switzerland, Norway and Sweden are using AC railroad net power-supply system with rated 16.7 Hz frequency modulated from 15.69 Hz to 17.36 Hz. The power supply frequency contam...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-4-16
更新日期：2005-03-15 00:00:00
abstract：BACKGROUND:Rotational osteotomy is frequently indicated to correct excessive femoral anteversion in cerebral palsy patients. Angled blade plate is the standard fixation device used when performed in the proximal femur, but extensile exposure is required for plate accommodation. The authors developed a short locked intr...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-10-57
更新日期：2011-06-28 00:00:00
abstract：BACKGROUND:Stroke is one of the major causes of morbidity and mortality. Its recovery and treatment depends on close clinical monitoring by a clinician especially during the first few hours after the onset of stroke. Patients who do not exhibit early motor recovery post thrombolysis may benefit from more aggressive tre...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-12-33
更新日期：2013-04-16 00:00:00
abstract：BACKGROUND:This work deals with copyright protection of digital images, an issue that needs protection of intellectual property rights. It is an important issue with a large number of medical images interchanged on the Internet every day. So, it is a challenging task to ensure the integrity of received images as well a...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-015-0101-x
更新日期：2015-11-25 00:00:00
abstract：BACKGROUND:In literature, the effect of the inflow boundary condition was investigated by examining the impact of the waveform and the shape of the spatial profile of the inlet velocity on the cardiac hemodynamics. However, not much work has been reported on comparing the effect of the different combinations of the inl...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/1475-925X-14-S1-S6
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Nonnegative matrix factorization (NMF) has been successfully used for electroencephalography (EEG) spectral analysis. Since NMF was proposed in the 1990s, many adaptive algorithms have been developed. However, the performance of their use in EEG data analysis has not been fully compared. Here, we provide a c...
journal_title：Biomedical engineering online
pub_type： 杂志文章
doi：10.1186/s12938-020-00796-x
更新日期：2020-07-31 00:00:00
