Motor recovery monitoring using acceleration measurements in post acute stroke patients.

Abstract:

BACKGROUND:Stroke is one of the major causes of morbidity and mortality. Its recovery and treatment depends on close clinical monitoring by a clinician especially during the first few hours after the onset of stroke. Patients who do not exhibit early motor recovery post thrombolysis may benefit from more aggressive treatment. METHOD:A novel approach for monitoring stroke during the first few hours after the onset of stroke using a wireless accelerometer based motor activity monitoring system is developed. It monitors the motor activity by measuring the acceleration of the arms in three axes. In the presented proof of concept study, the measured acceleration data is transferred wirelessly using iMote2 platform to the base station that is equipped with an online algorithm capable of calculating an index equivalent to the National Institute of Health Stroke Score (NIHSS) motor index. The system is developed by collecting data from 15 patients. RESULTS:We have successfully demonstrated an end-to-end stroke monitoring system reporting an accuracy of calculating stroke index of more than 80%, highest Cohen's overall agreement of 0.91 (with excellent κ coefficient of 0.76). CONCLUSION:A wireless accelerometer based 'hot stroke' monitoring system is developed to monitor the motor recovery in acute-stroke patients. It has been shown to monitor stroke patients continuously, which has not been possible so far with high reliability.

journal_name

Biomed Eng Online

authors

Gubbi J,Rao AS,Fang K,Yan B,Palaniswami M

doi

10.1186/1475-925X-12-33

subject

Has Abstract

pub_date

2013-04-16 00:00:00

pages

33

issn

1475-925X

pii

1475-925X-12-33

journal_volume

12

pub_type

杂志文章
  • Data-guide for brain deformation in surgery: comparison of linear and nonlinear models.

    abstract:BACKGROUND:Pre-operative imaging devices generate high-resolution images but intra-operative imaging devices generate low-resolution images. To use high-resolution pre-operative images during surgery, they must be deformed to reflect intra-operative geometry of brain. METHODS:We employ biomechanical models, guided by ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-9-51

    authors: Hamidian H,Soltanian-Zadeh H,Faraji-Dana R,Gity M

    更新日期:2010-09-15 00:00:00

  • Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: an IVUS-based fluid-structure interaction multi-patient study.

    abstract:BACKGROUND:Atherosclerotic plaque progression and rupture are believed to be associated with mechanical stress conditions. In this paper, patient-specific in vivo intravascular ultrasound (IVUS) coronary plaque image data were used to construct computational models with fluid-structure interaction (FSI) and cyclic bend...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-32

    authors: Fan R,Tang D,Yang C,Zheng J,Bach R,Wang L,Muccigrosso D,Billiar K,Zhu J,Ma G,Maehara A,Mintz GS

    更新日期:2014-03-26 00:00:00

  • Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism.

    abstract:BACKGROUND:A computational model of myocardial energy metabolism was used to assess the metabolic responses to normal and reduced myocardial blood flow. The goal was to examine to what extent glycolysis and lactate formation are controlled by the supply of glycolytic substrate and/or the cellular redox (NADH/NAD+) and ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-3-15

    authors: Salem JE,Stanley WC,Cabrera ME

    更新日期:2004-06-02 00:00:00

  • On the viability of implantable electrodes for the natural control of artificial limbs: review and discussion.

    abstract::The control of robotic prostheses based on pattern recognition algorithms is a widely studied subject that has shown promising results in acute experiments. The long-term implementation of this technology, however, has not yet been achieved due to practical issues that can be mainly attributed to the use of surface el...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章,评审

    doi:10.1186/1475-925X-11-33

    authors: Ortiz-Catalan M,Brånemark R,Håkansson B,Delbeke J

    更新日期:2012-06-20 00:00:00

  • Feature extraction for the analysis of colon status from the endoscopic images.

    abstract:BACKGROUND:Extracting features from the colonoscopic images is essential for getting the features, which characterizes the properties of the colon. The features are employed in the computer-assisted diagnosis of colonoscopic images to assist the physician in detecting the colon status. METHODS:Endoscopic images contai...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925x-2-9

    authors: Tjoa MP,Krishnan SM

    更新日期:2003-04-08 00:00:00

  • Identification of dental root canals and their medial line from micro-CT and cone-beam CT records.

    abstract:BACKGROUND:Shape of the dental root canal is highly patient specific. Automated identification methods of the medial line of dental root canals and the reproduction of their 3D shape can be beneficial for planning endodontic interventions as severely curved root canals or multi-rooted teeth may pose treatment challenge...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-11-81

    authors: Benyó B

    更新日期:2012-10-29 00:00:00

  • Neonatal non-contact respiratory monitoring based on real-time infrared thermography.

    abstract:BACKGROUND:Monitoring of vital parameters is an important topic in neonatal daily care. Progress in computational intelligence and medical sensors has facilitated the development of smart bedside monitors that can integrate multiple parameters into a single monitoring system. This paper describes non-contact monitoring...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-93

    authors: Abbas AK,Heimann K,Jergus K,Orlikowsky T,Leonhardt S

    更新日期:2011-10-20 00:00:00

  • A perceptual map for gait symmetry quantification and pathology detection.

    abstract:BACKGROUND:The gait movement is an essential process of the human activity and the result of collaborative interactions between the neurological, articular and musculoskeletal systems, working efficiently together. This explains why gait analysis is important and increasingly used nowadays for the diagnosis of many dif...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-015-0097-2

    authors: Moevus A,Mignotte M,de Guise JA,Meunier J

    更新日期:2015-10-29 00:00:00

  • Performance evaluation of a motor-imagery-based EEG-Brain computer interface using a combined cue with heterogeneous training data in BCI-Naive subjects.

    abstract:BACKGROUND:The subjects in EEG-Brain computer interface (BCI) system experience difficulties when attempting to obtain the consistent performance of the actual movement by motor imagery alone. It is necessary to find the optimal conditions and stimuli combinations that affect the performance factors of the EEG-BCI syst...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-91

    authors: Choi D,Ryu Y,Lee Y,Lee M

    更新日期:2011-10-12 00:00:00

  • A reference dataset for verifying numerical electrophysiological heart models.

    abstract:BACKGROUND:The evaluation, verification and comparison of different numerical heart models are difficult without a commonly available database that could be utilized as a reference. Our aim was to compile an exemplary dataset. METHODS:The following methods were employed: Magnetic Resonance Imaging (MRI) of heart and t...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-11

    authors: Koch H,Bousseljot RD,Kosch O,Jahnke C,Paetsch I,Fleck E,Schnackenburg B

    更新日期:2011-01-27 00:00:00

  • Real-time feature extraction of P300 component using adaptive nonlinear principal component analysis.

    abstract:BACKGROUND:The electroencephalography (EEG) signals are known to involve the firings of neurons in the brain. The P300 wave is a high potential caused by an event-related stimulus. The detection of P300s included in the measured EEG signals is widely investigated. The difficulties in detecting them are that they are mi...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-10-83

    authors: Turnip A,Hong KS,Jeong MY

    更新日期:2011-09-23 00:00:00

  • Correction to: Effects of astrocyte on neuronal outgrowth in a layered 3D structure.

    abstract::It was highlighted that the original article [1] contained an error in the Acknowledgments section. ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12938-019-0707-5

    authors: Fang A,Li D,Hao Z,Wang L,Pan B,Gao L,Qu X,He J

    更新日期:2019-08-08 00:00:00

  • Automated identification of reference genes based on RNA-seq data.

    abstract:BACKGROUND:Gene expression analyses demand appropriate reference genes (RGs) for normalization, in order to obtain reliable assessments. Ideally, RG expression levels should remain constant in all cells, tissues or experimental conditions under study. Housekeeping genes traditionally fulfilled this requirement, but the...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-017-0356-5

    authors: Carmona R,Arroyo M,Jiménez-Quesada MJ,Seoane P,Zafra A,Larrosa R,Alché JD,Claros MG

    更新日期:2017-08-18 00:00:00

  • Development of a mathematical model to estimate intra-tumor oxygen concentrations through multi-parametric imaging.

    abstract:BACKGROUND:Tumor hypoxia is involved in every stage of solid tumor development: formation, progression, metastasis, and apoptosis. Two types of hypoxia exist in tumors-chronic hypoxia and acute hypoxia. Recent studies indicate that the regional hypoxia kinetics is closely linked to metastasis and therapeutic responses,...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0235-5

    authors: Lee CW,Stantz KM

    更新日期:2016-10-12 00:00:00

  • A development of assistant surgical robot system based on surgical-operation-by-wire and hands-on-throttle-and-stick.

    abstract:BACKGROUND:Robot-assisted laparoscopic surgery offers several advantages compared with open surgery and conventional minimally invasive surgery. However, one issue that needs to be resolved is a collision between the robot arm and the assistant instrument. This is mostly caused by miscommunication between the surgeon a...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0189-7

    authors: Kim M,Lee C,Park WJ,Suh YS,Yang HK,Kim HJ,Kim S

    更新日期:2016-05-20 00:00:00

  • The use of chilled condensers for the recovery of perfluorocarbon liquid in an experimental model of perfluorocarbon vapour loss during neonatal partial liquid ventilation.

    abstract:BACKGROUND:Perfluorocarbon (PFC) vapour in the expired gases during partial liquid ventilation should be prevented from entering the atmosphere and recovered for potential reuse. This study aimed to determine how much PFC liquid could be recovered using a conventional humidified neonatal ventilator with chilled condens...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-6-19

    authors: Dunster KR,Davies MW,Fraser JF

    更新日期:2007-05-31 00:00:00

  • Evaluation of three force-position hybrid control methods for a robot-based biological joint-testing system.

    abstract:BACKGROUND:Robot-based joint-testing systems (RJTS) can be used to perform unconstrained laxity tests, measuring the stiffness of a degree of freedom (DOF) of the joint at a fixed flexion angle while allowing the other DOFs unconstrained movement. Previous studies using the force-position hybrid (FPH) control method pr...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0195-9

    authors: Hsieh HJ,Hu CC,Lu TW,Lu HL,Kuo MY,Kuo CC,Hsu HC

    更新日期:2016-06-07 00:00:00

  • Prospects of implant with locking plate in fixation of subtrochanteric fracture: experimental demonstration of its potential benefits on synthetic femur model with supportive hierarchical nonlinear hyperelastic finite element analysis.

    abstract:BACKGROUND:Effective fixation of fracture requires careful selection of a suitable implant to provide stability and durability. Implant with a feature of locking plate (LP) has been used widely for treating distal fractures in femur because of its favourable clinical outcome, but its potential in fixing proximal fractu...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-11-23

    authors: Latifi MH,Ganthel K,Rukmanikanthan S,Mansor A,Kamarul T,Bilgen M

    更新日期:2012-04-30 00:00:00

  • A multivariate relationship between the kinematic and clinical parameters of knee osteoarthritis population.

    abstract:BACKGROUND:Biomechanical and clinical parameters contribute very closely to functional evaluations of the knee joint. To better understand knee osteoarthritis joint function, the association between a set of knee biomechanical data and a set of clinical parameters of an osteoarthritis population (OA) is investigated in...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-019-0676-8

    authors: Bensalma F,Mezghani N,Ouakrim Y,Fuentes A,Choinière M,Bureau NJ,Durand M,Hagemeister N

    更新日期:2019-05-15 00:00:00

  • Two-hierarchical nonnegative matrix factorization distinguishing the fluorescent targets from autofluorescence for fluorescence imaging.

    abstract:BACKGROUND:Nonnegative matrix factorization (NMF) has been used in blind fluorescence unmixing for multispectral in-vivo fluorescence imaging, which decomposes a mixed source data into a set of constituent fluorescence spectra and corresponding concentrations. However, most classical NMF algorithms have ill convergence...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-015-0107-4

    authors: Huang S,Zhao Y,Qin B

    更新日期:2015-12-15 00:00:00

  • Three-dimensional dominant frequency mapping using autoregressive spectral analysis of atrial electrograms of patients in persistent atrial fibrillation.

    abstract:BACKGROUND:Areas with high frequency activity within the atrium are thought to be 'drivers' of the rhythm in patients with atrial fibrillation (AF) and ablation of these areas seems to be an effective therapy in eliminating DF gradient and restoring sinus rhythm. Clinical groups have applied the traditional FFT-based a...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0143-8

    authors: Salinet JL,Masca N,Stafford PJ,Ng GA,Schlindwein FS

    更新日期:2016-03-08 00:00:00

  • Effects of 8-week swimming training on carotid arterial stiffness and hemodynamics in young overweight adults.

    abstract:BACKGROUND:Exercise has been found to either reduce or increase arterial stiffness. Land-based exercise modalities have been documented as effective physical therapies to decrease arterial stiffness. However, these land-based exercise modalities may not be suitable for overweight individuals, in terms of risks of joint...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-016-0274-y

    authors: Yuan WX,Liu HB,Gao FS,Wang YX,Qin KR

    更新日期:2016-12-28 00:00:00

  • Investigation of red blood cell mechanical properties using AFM indentation and coarse-grained particle method.

    abstract:BACKGROUND:Red blood cells (RBCs) deform significantly and repeatedly when passing through narrow capillaries and delivering dioxygen throughout the body. Deformability of RBCs is a key characteristic, largely governed by the mechanical properties of the cell membrane. This study investigated RBC mechanical properties ...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-017-0429-5

    authors: Barns S,Balanant MA,Sauret E,Flower R,Saha S,Gu Y

    更新日期:2017-12-19 00:00:00

  • An inverse method to determine the mechanical properties of the iris in vivo.

    abstract:BACKGROUND:Understanding the mechanical properties of the iris can help to have an insight into the eye diseases with abnormalities of the iris morphology. Material parameters of the iris were simply calculated relying on the ex vivo experiment. However, the mechanical response of the iris in vivo is different from tha...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-66

    authors: Zhang K,Qian X,Mei X,Liu Z

    更新日期:2014-05-30 00:00:00

  • Fine-grain recordings of the electrically evoked compound action potential amplitude growth function in cochlear implant recipients.

    abstract:BACKGROUND:In cochlear implants (CI) measuring the electrically evoked compound action potential (ECAP) has become an important tool for verifying the electrode-nerve interface as well as establishing a basis for a map to program the speech processor. In a standard clinical setup recordings are averaged over 25-100 rep...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-018-0588-z

    authors: Gärtner L,Lenarz T,Büchner A

    更新日期:2018-10-19 00:00:00

  • EZ Entropy: a software application for the entropy analysis of physiological time-series.

    abstract:BACKGROUND:Entropy analysis has been attracting increasing attentions in the recent two or three decades. It assesses complexity, or irregularity, of time-series which is extraordinarily relevant to physiology and diseases as demonstrated by tremendous studies. However, the complexity can hardly be appreciated by tradi...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/s12938-019-0650-5

    authors: Li P

    更新日期:2019-03-20 00:00:00

  • Extraction of average neck flexion angle during swallowing in neutral and chin-tuck positions.

    abstract:BACKGROUND:A common but debated technique in the management of swallowing difficulties is the chin tuck swallow, where the neck is flexed forward prior to swallowing. Natural variations in chin tuck angles across individuals may contribute to the differential effectiveness of the technique. METHODOLOGY:To facilitate t...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-8-25

    authors: Hung D,Sejdić E,Steele CM,Chau T

    更新日期:2009-10-07 00:00:00

  • Using stochastic modelling to identify unusual continuous glucose monitor measurements and behaviour, in newborn infants.

    abstract:BACKGROUND:Abnormal blood glucose (BG) concentrations have been associated with increased morbidity and mortality in both critically ill adults and infants. Furthermore, hypoglycaemia and glycaemic variability have both been independently linked to mortality in these patients. Continuous Glucose Monitoring (CGM) device...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-11-45

    authors: Signal M,Le Compte A,Harris DL,Weston PJ,Harding JE,Chase JG,CHYLD Study Group.

    更新日期:2012-08-06 00:00:00

  • The effect of baseline pressure errors on an intracranial pressure-derived index: results of a prospective observational study.

    abstract:BACKGROUND:In order to characterize the intracranial pressure-volume reserve capacity, the correlation coefficient (R) between the ICP wave amplitude (A) and the mean ICP level (P), the RAP index, has been used to improve the diagnostic value of ICP monitoring. Baseline pressure errors (BPEs), caused by spontaneous shi...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-13-99

    authors: Eide PK,Sorteberg A,Meling TR,Sorteberg W

    更新日期:2014-07-23 00:00:00

  • Monitoring and analysis of dynamic growth of human embryonic stem cells: comparison of automated instrumentation and conventional culturing methods.

    abstract:BACKGROUND:Human embryonic stem cells (hESCs) are a potential source of cells for use in regenerative medicine. Automation of culturing, monitoring and analysis is crucial for fast and reliable optimization of hESC culturing methods. Continuous monitoring of living cell cultures can reveal more information and is faste...

    journal_title:Biomedical engineering online

    pub_type: 杂志文章

    doi:10.1186/1475-925X-6-11

    authors: Narkilahti S,Rajala K,Pihlajamäki H,Suuronen R,Hovatta O,Skottman H

    更新日期:2007-04-12 00:00:00