miRNAs associated with immune response in teleost fish.

abstract：:In this study, we examined the expression of epithelial Na(+) channel (ENaC) subunits in human peripheral blood lymphocytes, human lymph nodes and molluscan immunocytes using non-radioactive in situ hybridization. The results showed that T lymphocytes express the ENaC gamma subunit mRNA, and B lymphocytes the ENaC bet...

journal_title：Developmental and comparative immunology

authors： Ottaviani E,Franchini A,Mandrioli M,Saxena A,Hanukoglu A,Hanukoglu I

更新日期：2002-06-01 00:00:00

abstract：:Thymic non-lymphoid cells have been shown to influence the differentiation of T-lymphocytes. Large numbers of non-lymphoid cells are concentrated in the thymic medullary zone. A morphometric analysis of these cells in the medulla identified little change in their absolute number and volume density during thymic develo...

journal_title：Developmental and comparative immunology

authors： Higley HR,O'Morchoe CC

更新日期：1984-07-01 00:00:00

abstract：:Hemolytic activity in coelomic fluid of Eisenia fetida (ECF) is due to three proteins H1, H2, H3 with molecular weights of 46, 43 and 40 kD, respectively. These proteins were isolated by preparative PAGE. H1 and H2 were shown to be stable in SDS and alpha-2-ME whereas H3 splits into two fragments with molecular weight...

journal_title：Developmental and comparative immunology

authors： Eue I,Kauschke E,Mohrig W,Cooper EL

更新日期：1998-01-01 00:00:00

abstract：:Lysozymes as an important immune factor, play vital roles in innate immune response against pathogen infection. In the present study, one c-type and g-type lysozymes were identified from Chinese giant salamander (Andrias davidianus). They shared highly conserved structural features with lysozymes from other species. S...

journal_title：Developmental and comparative immunology

authors： Yang H,Liu R,Cui D,Liu H,Xiong D,Liu X,Wang L

更新日期：2017-07-01 00:00:00

abstract：:The snail Biomphalaria glabrata kills the blood fluke Schistosoma mansoni by a mechanism involving production of hydrogen peroxide, the enzymatic product of cytosolic Cu/Zn superoxide dismutase (SOD1). This enzyme exhibits higher activity in blood cells (hemocytes) from a predominantly resistant strain of B. glabrata ...

journal_title：Developmental and comparative immunology

authors： Bender RC,Goodall CP,Blouin MS,Bayne CJ

更新日期：2007-01-01 00:00:00

abstract：:Freshwater crayfish is an important commodity as well as a successful model for studies on crustacean immunity. Due to the ease with which they are kept and the available methods for hemocyte separation and culture they have proven to be very useful. Here, recent progress regarding pattern recognition, immune effector...

journal_title：Developmental and comparative immunology

authors： Cerenius L,Söderhäll K

更新日期：2018-03-01 00:00:00

abstract：:To date, many immunoglobulin (Ig) genes have been identified in diverse teleost species, but the contributions of different types of light chain (IgL) to the immune response remain unclear. Screening of a stimulated kidney cDNA library from orange-spotted grouper (Osg, Epinephelus coioides) resulted in the identificat...

journal_title：Developmental and comparative immunology

authors： Wu MS,Cheng CA,Lin CH,Lee CY,Tseng SJ,Tzeng CS,Chang CY

更新日期：2013-03-01 00:00:00

abstract：:The process of myeloid cell development (myelopoiesis) in fish has mainly been studied in three cyprinid species: zebrafish (Danio rerio), ginbuna carp (Carassius auratus langsdorfii) and goldfish (C. auratus, L.). Our studies on goldfish myelopoiesis have utilized in vitro generated primary kidney macrophage (PKM) cu...

journal_title：Developmental and comparative immunology

authors： Katzenback BA,Katakura F,Belosevic M

更新日期：2016-05-01 00:00:00

abstract：:Infectious hematopoietic necrosis virus (IHNV) is a common pathogen that causes severe disease in the salmonid aquaculture industry. Recent work demonstrated that autophagy plays an important role in pathogen invasion by activating innate and adaptive immunity. This study investigated the relationship between IHNV and...

journal_title：Developmental and comparative immunology

authors： Zhao JZ,Xu LM,Liu M,Zhang ZY,Yin JS,Liu HB,Lu TY

更新日期：2017-12-01 00:00:00

abstract：:Studies of the innate immune system have recently shown that, in addition to its role in producing the primary response that slows down pathogens, it may also play an important role in initiating and directing the type of response that the adaptive immune system makes. These discoveries have shown a complex web of con...

journal_title：Developmental and comparative immunology

authors： Dixon B,Stet RJ

更新日期：2001-10-01 00:00:00

abstract：:A range of marine invertebrates were screened for prophenoloxidase (a marker protein of the prophenoloxidase activating system) in the coelomic fluid or hemolymph. The crustaceans and the ascidian, Ciona intestinalis, displayed strongest activity, with low levels found in the starfish, Asterias rubens, the sea urchin,...

journal_title：Developmental and comparative immunology

authors： Smith VJ,Söderhäll K

更新日期：1991-10-01 00:00:00

abstract：:Serine protease inhibitors (SPIs) play a key role in physiological responses by controlling protease activities. In this study, we studied the biochemical functions of serpin-15, an SPI, from Bombyx mori (Bmserpin-15). Recombinant Bmserpin-15 was expressed in Escherichia coli cells and used to raise rabbit anti-Bmserp...

journal_title：Developmental and comparative immunology

authors： Liu D,Wang L,Yang L,Qian C,Wei G,Dai L,Li J,Zhu B,Liu C

更新日期：2015-07-01 00:00:00

abstract：:V(D)J recombination is a somatic gene rearrangement process that assembles antigen receptor genes from individual segments during lymphocyte development. The access of the RAG1/RAG2 recombinase to these gene segments is regulated at the level of chromatin modifications, in particular histone tail modifications. Trimet...

journal_title：Developmental and comparative immunology

authors： Wilson DR,Norton DD,Fugmann SD

更新日期：2008-01-01 00:00:00

abstract：:While genetic evidence points towards an absence of Toll-Like Receptors (TLRs) in Platyhelminthes, the Toll/IL-1 Receptor (TIR)-domains that drive the assembly of signalling complexes downstream TLR are present in these organisms. Here, we undertook the characterisation of the repertoire of TIR-domain containing prote...

journal_title：Developmental and comparative immunology

authors： Tsoumtsa LL,Sougoufara S,Torre C,Lemichez E,Pontarotti P,Ghigo E

更新日期：2018-09-01 00:00:00

abstract：:Toll-like receptor 5 (TLR5) is responsible for the recognition of bacterial flagellin in mammals and play an important role in innate immunity. In the present study, a TLR5M gene was cloned from turbot, Scophthalmus maximus, and its immune responsive expression was subsequently studied in vivo. The Scophthalmus maximu...

journal_title：Developmental and comparative immunology

authors： Liu D,Chen J,Li S,Hu G

更新日期：2018-08-01 00:00:00

abstract：:Surfactant Protein A (SP-A) is a collagenous C-type lectin (collectin) that plays an important role in the early stage of the host immune response. In chicken, SP-A (cSP-A) is expressed as a 26 kDa glycosylated protein in the lung. Using immunohistochemistry, cSP-A protein was detected mainly in the lung lining fluid ...

journal_title：Developmental and comparative immunology

authors： Zhang W,Cuperus T,van Dijk A,Skjødt K,Hansen S,Haagsman HP,Veldhuizen EJ

更新日期：2016-08-01 00:00:00

abstract：:Effects of endogenous Notch ligands Jagged-1 and Delta-1 on maturation markers in adult mouse lymphocytes were checked in vitro on putative thymocyte precursors from bone marrow and on DN3 cells from the thymus. Both populations were cocultured with stromal cells (Small M, Histochem Cell Biol 2005;123:513) naturally e...

journal_title：Developmental and comparative immunology

authors： Small M

更新日期：2006-01-01 00:00:00

abstract：:Spleen cells from rats 2 to 132 days old were cultured with 1-125 micrograms/ml Concanavalin A (Con A). At high doses of Con A, the high spontaneous thymidine uptake of spleen cells from rats 15 to 21 days old was suppressed, whereas spleen cells from younger rats showed no suppression of spontaneous mitogenesis at eq...

journal_title：Developmental and comparative immunology

authors： Middleton PA,Bullock WW

更新日期：1984-10-01 00:00:00

abstract：:In crustaceans, lipopolysaccharide- and β-1,3-glucan-binding protein (LGBP) plays an important role in innate immunity by mediating the recognition of pathogens to host cells. Hereby, LGBP was cloned from Fenneropenaeus merguiensis hepatopancreas. Its full-length cDNA (1280 bp) had an open reading frame of 1101 bp, en...

journal_title：Developmental and comparative immunology

authors： Chaosomboon A,Phupet B,Rattanaporn O,Runsaeng P,Utarabhand P

更新日期：2017-02-01 00:00:00

abstract：:Dual oxidases (DUOXs) were originally identified as NADPH oxidases (NOXs), found to be associated with the reactive oxygen species (ROS) hydrogen peroxide (H2O2) production at the plasma membrane and crucial in host biological processes. In this study, SpDUOX1 and SpDUOX2 of mud crab (Scylla paramamosain) were identif...

journal_title：Developmental and comparative immunology

authors： Sun Z,Hao S,Gong Y,Zhang M,Aweya JJ,Tran NT,Zhang Y,Ma H,Li S

更新日期：2018-12-01 00:00:00

abstract：:The present study was conducted to evaluate the effects of dietary Pediococcus acidilactici (PA) and raffinose (RF) alone or in combination on growth performance, mucosal immune factors and immune related genes expression in common carp (Cyprinus carpio) juveniles. Fish with initial weight of 10.0 ± 2.5 g were fed the...

journal_title：Developmental and comparative immunology

authors： Hoseinifar SH,Hosseini M,Paknejad H,Safari R,Jafar A,Yousefi M,Van Doan H,Torfi Mozanzadeh M

更新日期：2019-05-01 00:00:00

abstract：:Infection of turkeys with the haemorrhagic enteritis virus (HEV), a type II avian adenovirus, results in varying rates of morbidity and mortality. The disease is characterised by splenomegaly, intestinal haemorrhage, sudden death and immunosuppression. The mechanisms of HEV immunopathogenesis and immunosuppression are...

journal_title：Developmental and comparative immunology

authors： Rautenschlein S,Sharma JM

更新日期：2000-03-01 00:00:00

abstract：:Immunity in insects has largely focused on responses towards bacteria and fungi, but recently the study of immune responses against viral infections has also received attention. In Lepidoptera, phagocytosis and encapsulation mediated by hemocytes, and apoptosis are part of the response against virus infection; however...

journal_title：Developmental and comparative immunology

authors： Terenius O

更新日期：2008-01-01 00:00:00

abstract：:Corals form the framework of the world's coral reefs and are under threat from increases in disease and bleaching (symbiotic dysfunction), yet the mechanisms of pathogen and symbiont recognition remain largely unknown. Here we describe the isolation and characterisation of an ancient mannose-binding lectin in the cora...

journal_title：Developmental and comparative immunology

authors： Kvennefors EC,Leggat W,Hoegh-Guldberg O,Degnan BM,Barnes AC

更新日期：2008-01-01 00:00:00

abstract：:In a previous report we described the existence of two structural and antigenic variants of light chains in serum trout Igs, defined by mAbs 2H9 and 2A1. In this report, we analyse the cell distribution, the "in vitro" kinetics of production, and the ontogenic appearance of these two variants. Both variants were alrea...

journal_title：Developmental and comparative immunology

authors： Sánchez C,Alvarez A,Castillo A,Zapata A,Villena A,Domínguez J

更新日期：1995-01-01 00:00:00

abstract：:C-type lectins are a superfamily of Ca(2+) dependent carbohydrate-recognition proteins which play significant diverse roles in nonself-recognition and clearance of invaders. In the present study, a C-type lectin (CfLec-2) from Zhikong scallop Chlamys farreri was selected to investigate its functions in innate immunity...

journal_title：Developmental and comparative immunology

authors： Yang J,Qiu L,Wei X,Wang L,Wang L,Zhou Z,Zhang H,Liu L,Song L

更新日期：2010-12-01 00:00:00

abstract：:Cathepsins belongs to the cysteine protease family, which are activated by an acidic environment. They play essential biological roles in the innate immunity and development of animals. Here, we identified a 62 kDa cathepsin L-like protease from the silkworm Bombyx mori. It contained putative conserved domains, includ...

journal_title：Developmental and comparative immunology

authors： Sun YX,Chen C,Xu WJ,Abbas MN,Mu FF,Ding WJ,Zhang HJ,Li J

更新日期：2021-03-01 00:00:00

abstract：:The phagocytic hemocytes of four snail species were investigated for their ability to generate reactive oxygen metabolites upon stimulation by foreign material. Hemocytes of the pond snail Lymnaea stagnalis and of the garden snail Helix aspersa showed a luminol-dependent chemiluminescence (CL) when they phagocytosed z...

journal_title：Developmental and comparative immunology

authors： Dikkeboom R,van der Knaap WP,van den Bovenkamp W,Tijnagel JM,Bayne CJ

更新日期：1988-07-01 00:00:00

abstract：:A bovine interferon-kappa (BoIFN-κ) gene was amplified, which encodes a protein of 215 amino acids sharing 63% identity with human IFN-κ. BoIFN-κ was demonstrated to have antiviral and antiproliferative activities. Moreover, BoIFN-κ was shown to be highly sensitive to trypsin, however, it remained stable despite chang...

journal_title：Developmental and comparative immunology

authors： Guo Y,An D,Liu Y,Bao J,Luo X,Cheng X,Wang Y,Gao M,Wang J

更新日期：2017-02-01 00:00:00

abstract：:The production of B cells and the primary antibody repertoire in mammalian species other than rodents or man appears to depend on gut-associated lymphoid tissue. Bovine B cells are generated in ileal Peyer's patch from late gestational to juvenile age. However, little is known about where and when the bona fide B lymp...

journal_title：Developmental and comparative immunology

authors： Ekman A,Pessa-Morikawa T,Liljavirta J,Niku M,Iivanainen A

更新日期：2010-08-01 00:00:00