The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails.

abstract：:Dicer (Dcr) is the key protein of the RNA interference (RNAi) pathway. To investigate the role of the RNAi pathway in shrimp anti-viral immunity, Litopenaeus vannamei Dcr2 (designated as LvDcr2) was identified and characterized. The full-length cDNA of LvDcr2 was 5513bp long, with an open reading frame encoding a puta...

journal_title：Developmental and comparative immunology

authors： Chen YH,Jia XT,Zhao L,Li CZ,Zhang S,Chen YG,Weng SP,He JG

更新日期：2011-06-01 00:00:00

abstract：:C-type lectins (CTLs) are involved in cell-cell adhesion, recognition, and innate immunity in higher vertebrates, but little is known about CTLs in basal metazoans. The recent sequencing of the cnidarian Nematostella vectensis genome allowed us to explore the CTL-like gene family at the base of metazoan evolution. Six...

journal_title：Developmental and comparative immunology

authors： Wood-Charlson EM,Weis VM

更新日期：2009-08-01 00:00:00

abstract：:The different allelic forms of nine non-Mhc alloantigen systems of the chicken were examined for developmental expression on erythrocytes isolated from embryos and young chicks. Polyclonal alloantisera raised against the different antigens were used to detect these antigens on the cell surface by hemagglutination as w...

journal_title：Developmental and comparative immunology

authors： Kopti F,Stevens SL,Briles WE

更新日期：1999-10-01 00:00:00

abstract：:Toll-like receptors (TLRs)are pattern recognition receptors (PRRs) that are important in invertebrate innate immunity for the recognition and elimination of pathogens. Although they were reported in many fishes, Toll-like receptors subfamily contain a large number of members with different functions that need to resea...

journal_title：Developmental and comparative immunology

authors： Wu M,Zhu KC,Guo HY,Guo L,Liu B,Jiang SG,Zhang DC

更新日期：2021-04-01 00:00:00

abstract：:Insects are able to effectively recognize parasitoid eggs or larvae and to eliminate them by formation of a hemocytic capsule. Although the cellular process is now well documented, the genetic aspects of recognition of foreignness and the encapsulation process are still poorly understood. Experiments using the isofema...

journal_title：Developmental and comparative immunology

authors： Carton Y,Boulétreau M

更新日期：1985-04-01 00:00:00

abstract：:Freshwater crayfish is an important commodity as well as a successful model for studies on crustacean immunity. Due to the ease with which they are kept and the available methods for hemocyte separation and culture they have proven to be very useful. Here, recent progress regarding pattern recognition, immune effector...

journal_title：Developmental and comparative immunology

authors： Cerenius L,Söderhäll K

更新日期：2018-03-01 00:00:00

abstract：:This study was aimed at the identification of variations in humoral immunity parameters during the lactation period in macaque females, a recognized model in reproductive physiology and pathology. The importance of such evaluation is evidenced in particular by the central role played by the maternally transferred immu...

journal_title：Developmental and comparative immunology

authors： D'Ovidio MC,Pace M,Via F,Iale E,Turillazzi PG,Strom R

更新日期：1996-03-01 00:00:00

abstract：:Interaction between interleukin (IL)-5 and its receptor (IL-5R) is important for the regulation of immunity against worm infections, allergic reactions and B cell response in mammals. In this study, we identified a full-length cDNA encoding chicken IL-5R α-chain (chIL-5Rα). The deduced amino acid sequence showed 41-43...

journal_title：Developmental and comparative immunology

authors： Fukushima Y,Miyai T,Kumagae M,Horiuchi H,Furusawa S

更新日期：2012-07-01 00:00:00

abstract：:The RIG-I like helicases, RIG-I, mda5 and LGP2 are an evolutionarily conserved family of cytosolic pattern recognition receptors important in the recognition of viral RNA, and responsible for the innate induction of interferons and proinflammatory cytokines upon viral infection. Bats are natural reservoir hosts to a v...

journal_title：Developmental and comparative immunology

authors： Cowled C,Baker ML,Zhou P,Tachedjian M,Wang LF

更新日期：2012-04-01 00:00:00

abstract：:We have purified five types of lectins, named tachylectins, from circulating hemocytes and hemolymph plasma of the Japanese horseshoe crab, Tachypleus tridentatus. Tachylectin-1 interacts with Gram-negative bacteria probably through 2-keto-3-deoxyoctonate, one of the constituents of lipopolysaccharides (LPS). Tachylec...

journal_title：Developmental and comparative immunology

authors： Kawabata S,Iwanaga S

更新日期：1999-06-01 00:00:00

abstract：:The rainbow trout caspase 6 gene has been cloned and sequenced. The open reading frame consisted of 906bp, which translated into a protein of 302 amino acids, containing the caspase active site pentapeptide (QACRG) and the caspase family signature (HADADCFVCVFLSHG). Amino acids involved in catalysis and those known to...

journal_title：Developmental and comparative immunology

authors： Laing KJ,Holland J,Bonilla S,Cunningham C,Secombes CJ

更新日期：2001-05-01 00:00:00

abstract：:Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and plays multifunctional roles in the immune system. In the present study, a homolog of TRAIL from the Mongolian horse (named ecTRAIL) was identified and characterized. The 870-bp open reading frame encodes a poly...

journal_title：Developmental and comparative immunology

authors： Ma L,Sang M,Zhang J,Zhang S

更新日期：2017-02-01 00:00:00

abstract：:Since the 1990s White Spot Syndrome Virus (WSSV) has severely affected shrimp aquaculture worldwide causing a global pandemic of White Spot Disease (WSD) in penaeid culture. However, not all decapod species that can be infected by WSSV show the same susceptibility to the virus, thus raising interesting questions regar...

journal_title：Developmental and comparative immunology

authors： Peruzza L,Thamizhvanan S,Vimal S,Vinaya Kumar K,Shekhar MS,Smith VJ,Hauton C,Vijayan KK,Sahul Hameed AS

更新日期：2020-03-01 00:00:00

abstract：:MicroRNAs (miRNAs) have been identified as important post transcriptional regulators of gene expression. In higher vertebrates, a subset of miRNAs has been identified as important regulators of a number of key genes in immune system gene networks, and this paper review recent studies on miRNAs associated with immune r...

journal_title：Developmental and comparative immunology

authors： Andreassen R,Høyheim B

更新日期：2017-10-01 00:00:00

abstract：:Ascorbate is an essential nutrient commonly regarded as an antioxidant. In this study, using axenic brine shrimp and pathogenic strain Vibrio harveyi as the host-pathogen model, we confirmed that pretreatment of sodium ascorbate (NaAs), at an optimum concentration, was a prooxidant by generation of hydrogen peroxide, ...

journal_title：Developmental and comparative immunology

authors： Han B,Kaur VI,Baruah K,Nguyen VD,Bossier P

更新日期：2019-03-01 00:00:00

abstract：:The production of B cells and the primary antibody repertoire in mammalian species other than rodents or man appears to depend on gut-associated lymphoid tissue. Bovine B cells are generated in ileal Peyer's patch from late gestational to juvenile age. However, little is known about where and when the bona fide B lymp...

journal_title：Developmental and comparative immunology

authors： Ekman A,Pessa-Morikawa T,Liljavirta J,Niku M,Iivanainen A

更新日期：2010-08-01 00:00:00

abstract：:As physical barriers that separate teleost fish from the external environment, mucosae are also active immunological sites that protect them against exposure to microbes and stressors. In mammals, the sites where antigens are sampled from mucosal surfaces and where stimulation of naïve T and B lymphocytes occurs are k...

journal_title：Developmental and comparative immunology

authors： Salinas I,Zhang YA,Sunyer JO

更新日期：2011-12-01 00:00:00

abstract：:This study compared hemocyte responses of eastern and Pacific oysters to Perkinsus marinus, in vitro. Except for the percentage of hemocytes associated with P. marinus there was little or no significant difference between eastern and Pacific oysters with regard to their hemocytic response to P. marinus. In phagocytosi...

journal_title：Developmental and comparative immunology

authors： La Peyre JF,Chu FL,Vogelbein WK

更新日期：1995-07-01 00:00:00

abstract：:Much is now known about the vertebrate mechanisms involved in mucosal immunity, and the requirement of commensal microbiota at mucosal surfaces for the proper functioning of the immune system. In comparison, very little is known about the mechanisms of immunity at the barrier epithelia of non-vertebrate organisms. The...

journal_title：Developmental and comparative immunology

authors： Garcia-Garcia E,Galindo-Villegas J,Mulero V

更新日期：2013-07-01 00:00:00

abstract：:We have studied the chicken's pineal gland by light and electron microscopy at 3 and 4 weeks of age. The results indicated that lymphocytes, plasma cells, secretory cells, basophil and eosinophil granulocytes enter the parenchyma and a new histologically defined tissue is formed which we call lymphopineal tissue. Insi...

journal_title：Developmental and comparative immunology

authors： Olah I,Glick B

更新日期：1984-10-01 00:00:00

abstract：:A five-domain Kazal-type serine proteinase inhibitor, SPIPm2, from Penaeus monodon has recently been implicated in antiviral responses for it is up-regulated upon viral infection and needs further studies. The SPIPm2 genomic gene was composed of seven exons and six introns. The genomic DNA segments coding for each Kaz...

journal_title：Developmental and comparative immunology

authors： Donpudsa S,Ponprateep S,Prapavorarat A,Visetnan S,Tassanakajon A,Rimphanitchayakit V

更新日期：2010-10-01 00:00:00

abstract：:The chemokine RANTES plays an essential role in inflammation and immune response. In this study, we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription. Analyses of a series of 5' deletion constructs demons...

journal_title：Developmental and comparative immunology

authors： Wang D,Fang L,Li P,Chen Q,Luo R,Chen H,Xiao S

更新日期：2011-03-01 00:00:00

abstract：:As pattern recognition receptors, C-type lectins (CTLs) play important roles in immune system of crustaceans through identifying and binding to the conservative pathogen-associated molecular patterns (PAMPs) on pathogen surfaces. In this study, a new CTL, SpCTL-B, was identified from the hemocytes of mud crab Scylla p...

journal_title：Developmental and comparative immunology

authors： Wei X,Wang L,Sun W,Zhang M,Ma H,Zhang Y,Zhang X,Li S

更新日期：2018-07-01 00:00:00

abstract：:In this study, an IL-8 homologue has been cloned and identified from South African clawed frog Xenopus laevis (designated XlIL-8). The open reading frame (ORF) of XlIL-8 consists of 312 bases encoding a protein of 103 amino acids. The chemokine CXC domain, which contained Glu-Leu-Arg (ELR) motif and four cysteine resi...

journal_title：Developmental and comparative immunology

authors： Cui X,Han Y,Pan Y,Xu X,Ren W,Zhang S

更新日期：2011-11-01 00:00:00

abstract：:In order to find the immune-relevant factors responsible for the virus resistance in the WSSV-resistant shrimp, a suppression subtractive hybridization method was employed to identify differentially expressed genes and their expression profile in the hepatopancreas of the virus-resistant penaeid shrimp. Thirty five ge...

journal_title：Developmental and comparative immunology

authors： Pan D,He N,Yang Z,Liu H,Xu X

更新日期：2005-01-01 00:00:00

abstract：:The ontogeny of the rat thymus micro-environment and in particular the development of the interdigitating cell (IDC) and macrophage (M phi) populations has been studied. At day 15 of fetal life the thymus consisted of an epithelial primordium in which some Thy-1 positive thymocytes were present around local capillarie...

journal_title：Developmental and comparative immunology

authors： Duijvestijn AM,Sminia T,Köhler YG,Janse EM,Hoefsmit EC

更新日期：1984-10-01 00:00:00

abstract：:Avidin is well known for its high affinity to biotin and has been found in many egg-laying vertebrate species. However, little is known about avidin in invertebrate species to date. Here we clearly showed the presence of two avidin genes, Bjavidin1 and Bjavidin2, in the amphioxus Branchiostoma japonicum, the first one...

journal_title：Developmental and comparative immunology

authors： Guo X,Xin J,Wang P,Du X,Ji G,Gao Z,Zhang S

更新日期：2017-05-01 00:00:00

abstract：:Diverse immunoglobulin (Ig) domain-containing protein (DICP) family is a novel bony fish-specific multi-gene family encoding diversified immune receptors. However, their function and the implication of binding partners remain unknown. In this study, we first identified 28 DICPs from three gibel carp gynogenetic clones...

journal_title：Developmental and comparative immunology

authors： Gao FX,Lu WJ,Wang Y,Zhang QY,Zhang YB,Mou CY,Li Z,Zhang XJ,Liu CW,Zhou L,Gui JF

更新日期：2018-07-01 00:00:00

abstract：:Studies were undertaken to determine whether previously described reductions in splenic DC-SIGN expression in simian acquired immune deficiency syndrome (AIDS) are limited to pathogenic simian immunodeficiency virus (SIV) infection. DC-SIGN expression was evaluated by immunohistochemistry in lymphoid tissues from AIDS...

journal_title：Developmental and comparative immunology

authors： Yearley JH,Kanagy S,Anderson DC,Dalecki K,Pauley DR,Suwyn C,Donahoe RM,McClure HM,O'Neil SP

更新日期：2008-01-01 00:00:00

abstract：:Trypanosoma carassii is an extracellular parasite of economically important fish species that has evolved several strategies to circumvent host immune responses. Proteomic analysis of the excreted/secreted (ES) and surface molecules of the parasite has revealed a number of proteins that may be involved in host-parasit...

journal_title：Developmental and comparative immunology

authors： Oladiran A,Belosevic M

更新日期：2010-04-01 00:00:00