Abstract:
:Thymic non-lymphoid cells have been shown to influence the differentiation of T-lymphocytes. Large numbers of non-lymphoid cells are concentrated in the thymic medullary zone. A morphometric analysis of these cells in the medulla identified little change in their absolute number and volume density during thymic development in the rat. Expansion of thymic medullary volume with age was documented by planimetry. Several subtypes of medullary non-lymphoid cell were identified by electron microscopy, including both squamous and cystic epithelial cells, interdigitating cells and macrophages. Changes in their relative proportion during development were determined with the percentage of squamous epithelial cells declining, interdigitating cells increasing and the other cell types exhibiting little change. Subcellular evidence of secretory activity was sought by analysis of changes in the volume density of organelles in each of the non-lymphoid classes. Cystic enlargement in epithelial cells and a decrease in the volume density of macrophage inclusion bodies were noted but no clear morphometric trend could be correlated with increased secretory activity expected in the developing endocrine thymus.
journal_name
Dev Comp Immunoljournal_title
Developmental and comparative immunologyauthors
Higley HR,O'Morchoe CCdoi
10.1016/0145-305x(84)90102-2subject
Has Abstractpub_date
1984-07-01 00:00:00pages
711-9issue
3eissn
0145-305Xissn
1879-0089pii
0145-305X(84)90102-2journal_volume
8pub_type
杂志文章abstract::The ileal Peyer's patch (IPP) of young sheep is a site of diversification of the primary antibody repertoire and where involution takes place at young age. Tissue samples from the ileum were collected in 134 animals aged from 1 month to 6 years, and IPP follicle phenotypes were characterised. We describe a new type of...
journal_title:Developmental and comparative immunology
pub_type: 杂志文章
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journal_title:Developmental and comparative immunology
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
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更新日期:2019-09-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2005.02.005
更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2010.12.002
更新日期:2011-09-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
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更新日期:2016-09-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2008.03.008
更新日期:2008-01-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2018.03.005
更新日期:2018-07-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/0145-305x(84)90044-2
更新日期:1984-04-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2007.11.008
更新日期:2008-01-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2007.06.006
更新日期:2008-01-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/s0145-305x(00)00041-0
更新日期:2001-01-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/s0145-305x(00)00023-9
更新日期:2000-09-01 00:00:00
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pub_type: 杂志文章
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journal_title:Developmental and comparative immunology
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journal_title:Developmental and comparative immunology
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更新日期:1998-07-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2005.01.004
更新日期:2005-01-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2017.01.006
更新日期:2017-05-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/s0145-305x(97)00023-2
更新日期:1997-09-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章,评审
doi:10.1016/j.dci.2014.01.022
更新日期:2014-07-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2016.05.003
更新日期:2016-09-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章,评审
doi:10.1016/0145-305x(85)90002-3
更新日期:1985-07-01 00:00:00
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journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2014.10.006
更新日期:2015-01-01 00:00:00
abstract::γδ T cells are highly abundant in the blood and spleen of pigs but little is known about their functional differentiation. In this study the potential of the type-1 polarizing cytokines IL-12 and IL-18 in combination with IL-2 and Concanavalin A (ConA) to stimulate porcine γδ T cells was investigated. Stimulation of p...
journal_title:Developmental and comparative immunology
pub_type: 杂志文章
doi:10.1016/j.dci.2014.07.007
更新日期:2014-11-01 00:00:00
abstract::Age-equivalence shows that certain differentiative events and the onset of various types of immunocompetence follow the same sequence in all species as lymphocytes emerge during development. ...
journal_title:Developmental and comparative immunology
pub_type: 杂志文章,评审
doi:10.1016/s0145-305x(78)80003-2
更新日期:1978-07-01 00:00:00