Abstract:
:Diapause, a programmed developmental arrest, is common in insects, enabling them to survive adverse seasons. It is well established that pupal diapause is regulated by ecdysteroids secreted by the prothoracic glands (PGs), with cessation of ecdysteroid secretion after pupal ecdysis leading to pupal diapause. A major factor regulating the gland activity is prothoracicotropic hormone (PTTH) secreted from the brain. In our previous study, we demonstrated that the cessation of PTTH release after pupal ecdysis resulted in the inactivation of the PGs, leading to pupal diapause in the cabbage army moth Mamestra brassicae. Here we show that a neuropeptide myosuppressin also contributes to the inactivation of PGs at the initiation of diapause. Myosuppressin suppresses PTTH-stimulated activation of the PGs in vitro. Concentrations of myosuppressin in the hemolymph after pupal ecdysis are higher in diapause pupae than in nondiapause pupae.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yamada N,Kataoka H,Mizoguchi Adoi
10.1038/srep41651subject
Has Abstractpub_date
2017-01-31 00:00:00pages
41651issn
2045-2322pii
srep41651journal_volume
7pub_type
杂志文章abstract::Autophagy is a cellular homeostatic mechanism where proteins and organelles are digested and recycled to provide an alternative source of building blocks and energy to cells. The role of autophagy in cancer microenvironment is still poorly understood. Here, we present a microfluidic system allowing monitoring of the c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02172-7
更新日期:2017-05-17 00:00:00
abstract::The efficacy and safety of misoprostol alone for missed abortion varied with different regimens. To evaluate existing evidence for the medical management of missed abortion using misoprostol, we undertook a comprehensive review and meta-analysis. The electronic literature search was conducted using PubMed, the Cochran...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-017-01892-0
更新日期:2017-05-10 00:00:00
abstract::A panel of 32 candidate reference genes was used to identify the most stable genes for gene normalisation in quantitative RT-PCR studies using endometrial biopsies obtained from women with endometrial cancer (type 1 or type 2) and without cancer (controls). RNA from the biopsies was isolated, examined for purity and q...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64663-4
更新日期:2020-05-21 00:00:00
abstract:ABSTARCT:We demonstrate a novel route to control the filtering of spoof localized surface plasmons (LSPs) on the corrugated metal-insulator-metal (MIM) ring resonator. The spoof LSPs resonance modes can be effectively tuned to achieve broad passband (covering the quadrupole mode and the hexapole mode) by selecting prop...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14708-y
更新日期:2017-10-27 00:00:00
abstract::Spinal cord injury (SCI) is frequently accompanied by a degree of spontaneous functional recovery. The underlying mechanisms through which such recovery is generated remain elusive. In this study, we observed a significant spontaneous motor function recovery 14 to 28 days after spinal cord transection (SCT) in rats. U...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16911
更新日期:2015-11-23 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular matrix (ECM) genera...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/s41598-019-56268-3
更新日期:2019-12-24 00:00:00
abstract::In this study, we reported a new technique based on laser speckle flowgraphy to record the ocular blood flow in rabbits under deep anesthesia, and proposed parameters to characterize retinal ischemia. We applied the proposed technique to study the correlation of blood flow between the eyes of normal non-anesthetized a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24141-4
更新日期:2018-04-09 00:00:00
abstract::We present a novel, non-invasive magnetic resonance imaging (MRI) technique to assess real-time dynamic vasomodulation of the microvascular bed. Unlike existing perfusion imaging techniques, our method is sensitive only to blood volume and not flow velocity. Using graded gas challenges and a long-life, blood-pool T 1-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06983-6
更新日期:2017-08-07 00:00:00
abstract::Temperature-modulated space-charge-limited-current spectroscopy (TMSCLC) is applied to quantitatively evaluate the density of trap states in the band-gap with high energy resolution of semiconducting hybrid lead halide perovskite single crystals. Interestingly multicomponent deep trap states were observed in the pure ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40139-y
更新日期:2019-03-04 00:00:00
abstract::Aging is a highly controlled biological process characterized by a progressive deterioration of various cellular activities. One of several hallmarks of aging describes a link to transcriptional alteration, suggesting that it may impact the steady-state mRNA levels. We analyzed the mRNA steady-state levels of polyCAG-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10692
更新日期:2015-06-02 00:00:00
abstract::To improve the understanding of the complex biological processes underlying the development of non-alcoholic steatohepatitis (NASH), a multi-omics approach combining bulk RNA-sequencing based transcriptomics, quantitative proteomics and single-cell RNA-sequencing was used to characterize tissue biopsies from histologi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58059-7
更新日期:2020-01-24 00:00:00
abstract::Retinal diseases generally are vision-threatening conditions that warrant appropriate clinical decision-making which currently solely dependents upon extensive clinical screening by specialized ophthalmologists. In the era where molecular assessment has improved dramatically, we aimed at the identification of biomarke...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41595
更新日期:2017-01-27 00:00:00
abstract::Glucagon is a pancreatic hormone and increases the blood glucose levels. It may be incorporated in a dual hormone artificial pancreas, a device to automatically and continuously control blood glucose levels of individuals with diabetes. Artificial pancreas systems have been developed for use in the subcutaneous tissue...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70813-5
更新日期:2020-08-13 00:00:00
abstract::Tissue engineering scaffolds are used in conjunction with stem cells for the treatment of various diseases. A number of factors provided by the scaffolds affect the differentiation of stem cells. Mechanical cues that are part of the natural cellular microenvironment can both accelerate the differentiation toward parti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23214-8
更新日期:2018-03-22 00:00:00
abstract::A novel and convenient copper (II) bromide and 1,8-diazabicyclo[5.4.1]undec-7-ene (DBU) or 1,10-phenanthroline catalysis protocol for the construction of α-alkyl-β-keto sulfones via C(sp(3))-H bond functionalization followed by C(sp(3))-S bond formation between aryl ketones and sodium sulfinates at room temperature ha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18391
更新日期:2015-12-18 00:00:00
abstract::CLE peptide hormones are critical regulators of many cell proliferation and differentiation mechanisms in plants. These 12-13 amino acid glycosylated peptides play vital roles in a diverse range of plant tissues, including the shoot, root and vasculature. CLE peptides are also involved in controlling legume nodulation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09296-w
更新日期:2017-08-24 00:00:00
abstract::Intrasynovial tendon injuries are among the most challenging in orthopedics. Despite significant improvements in operative and rehabilitation methods, functional outcomes continue to be limited by adhesions, gap formation, and rupture. Adhesions result from excessive inflammation, whereas tendon gapping and rupture re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29474-8
更新日期:2018-07-23 00:00:00
abstract::Finding strategies to preserve quantum resources in open systems is nowadays a main requirement for reliable quantum-enhanced technologies. We address this issue by considering structured cavities embedding qubits driven by a control technique known as frequency modulation. We first study a single qubit in a lossy cav...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32661-2
更新日期:2018-09-24 00:00:00
abstract::Daphnia are important to understanding the biogeochemistry of aquatic ecosystems, mainly because of their ability to filter bacteria, algae and inorganic particles as well. Although there are many studies on the general effects that biotic and abiotic stressors, increased temperature and hypoxia, salinity, metals, pha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40777-2
更新日期:2019-03-07 00:00:00
abstract::Large classes of electronic, photonic, and acoustic crystals and quasi-crystals have been predicted to support topological wave-modes. Some of these modes are stabilized by certain symmetries but others occur as pure wave phenomena, hence they can be observed in many other media that support wave propagation. Surface ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21462-2
更新日期:2018-02-20 00:00:00
abstract::Zebrafish embryos are translucent and develop rapidly in individual eggs ex utero; they are widely used as models for embryogenesis and organ development for human diseases and drug discovery. Lysine crotonylation (Kcr) is a type of histone post-translational modifications discovered in 2011. Kcr dynamics are involved...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22069-3
更新日期:2018-02-26 00:00:00
abstract::Voice disorder such as vocal fatigue is a common and complex multifaceted clinical problem that presents a significant impact on quality of life. In this study, the functional near-infrared diffuse optical technique (fNIRS-DOT) was proposed as a novel approach for human vocal cords oxidative metabolism detection and a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16807-2
更新日期:2017-12-05 00:00:00
abstract::Pressure therapy has been proved to be an effective treatment for hypertrophic scars in a clinical setting. However, evidence-based data are controversial and the precise mechanism of action of this technique remains unknown. The aim of this study was to investigate the potential molecular mechanisms of pressure thera...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29840-6
更新日期:2018-08-07 00:00:00
abstract::Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype-specific effects on obesity...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04946-5
更新日期:2017-07-05 00:00:00
abstract::A cobalt sulfide/PVDF(Polyvinylidene Fluoride) composite was prepared by a simple blending method, and the microstructure of the composite was investigated through X-ray diffraction, scanning electron microscopy, and field emission scanning electron microscopy. Increased absorption properties at frequencies ranging fr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47037-3
更新日期:2019-07-19 00:00:00
abstract::Although biophysical yield responses to local warming have been studied, we know little about how crop yield growth-a function of climate and technology-responds to global temperature and socioeconomic changes. Here, we present the yield growth of major crops under warming conditions from preindustrial levels as simul...
journal_title:Scientific reports
pub_type: 历史文章,杂志文章
doi:10.1038/s41598-017-08214-4
更新日期:2017-08-10 00:00:00
abstract::Metallic nanostructures are of immense scientific interest owing to unexpectedly strong interaction with light in deep subwavelength scales. Resonant excitations of surface and cavity plasmonic modes mediate strong light localization in nanoscale objects. Nevertheless, the role of surface plasmon-polaritons (SPP) in l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05683
更新日期:2014-07-14 00:00:00
abstract::We experimentally perform the simulation of open quantum dynamics in single-qudit systems. Using a spatial light modulator as a dissipative optical device, we implement dissipative-dynamical maps onto qudits encoded in the transverse momentum of spontaneous parametric down-converted photon pairs. We show a well-contro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16049
更新日期:2015-11-03 00:00:00
abstract::Autism is a common and often severe neurodevelopmental disorder for which diverse pathophysiological processes have been proposed. Recent gene expression data comparing autistic and control brains suggest that the normal differential gene expression between frontal and temporal cortex is attenuated in autistic brains....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01831
更新日期:2013-01-01 00:00:00
abstract::Multiple infections of avian influenza viruses (AIVs) in poultry or wild birds contribute to the continued evolution of H5 subtype viruses in nature and provide potential recombination of AIVs of different origins. In this study, we carried out surveillance of AIVs in ducks, geese and the environment of a community in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25549
更新日期:2016-05-06 00:00:00