Ocular Blood Flow in Rabbits under Deep Anesthesia: A Real-Time Measurement Technique and Its Application in Characterizing Retinal Ischemia.

abstract：:Biological validation of new radiotherapy modalities is essential to understand their therapeutic potential. Antiprotons have been proposed for cancer therapy due to enhanced dose deposition provided by antiproton-nucleon annihilation. We assessed cellular DNA damage and relative biological effectiveness (RBE) of a cl...

journal_title：Scientific reports

authors： Kavanagh JN,Currell FJ,Timson DJ,Savage KI,Richard DJ,McMahon SJ,Hartley O,Cirrone GA,Romano F,Prise KM,Bassler N,Holzscheiter MH,Schettino G

更新日期：2013-01-01 00:00:00

abstract：:In order to foster animal welfare as well as high quality of research, many countries regulate by law that the severity of animal experiments must be evaluated and considered when performing biomedical research. It is well accepted that multiple parameters rather than a single readout parameter should be applied to de...

journal_title：Scientific reports

authors： Tang G,Seume N,Häger C,Kumstel S,Abshagen K,Bleich A,Vollmar B,Talbot SR,Zhang X,Zechner D

更新日期：2020-11-13 00:00:00

abstract：:High mobility channel thin-film-transistor (TFT) is crucial for both display and future generation integrated circuit. We report a new metal-oxide TFT that has an ultra-thin 4.5 nm SnO2 thickness for both active channel and source-drain regions, very high 147 cm(2)/Vs field-effect mobility, high ION/IOFF of 2.3 × 10(7...

journal_title：Scientific reports

authors： Shih CW,Chin A,Lu CF,Su WF

更新日期：2016-01-08 00:00:00

abstract：:Microorganisms in vertebrate guts have been recognized as important symbionts influencing host life. However, it remains unclear about the gut microbiota in long-distance migratory Anseriformes herbivores, which could be functionally important for these wetland-dependent animals. We collected faeces of the greater whi...

journal_title：Scientific reports

authors： Yang Y,Deng Y,Cao L

更新日期：2016-09-07 00:00:00

abstract：:C-phycocyanin (C-PC) pigment, as a natural blue dye, has particular applications in various fields. It is a water-soluble protein which has anticancer, antioxidant and anti-inflammatory properties. Here, we introduce an efficient procedure for the purification of C-PC pigment, followed by conducting a comprehensive in...

journal_title：Scientific reports

authors： Safaei M,Maleki H,Soleimanpour H,Norouzy A,Zahiri HS,Vali H,Noghabi KA

更新日期：2019-07-01 00:00:00

abstract：:Diatoms are among the most diverse eukaryotic microorganisms on Earth, they are responsible for a large fraction of primary production in the oceans and can be found in different habitats. Pseudo-nitzschia are marine planktonic diatoms responsible for blooms in coastal and oceanic waters. We analyzed the transcriptome...

journal_title：Scientific reports

authors： Di Dato V,Musacchia F,Petrosino G,Patil S,Montresor M,Sanges R,Ferrante MI

更新日期：2015-07-20 00:00:00

abstract：:Er(3+) doped oxyfluoride tellurite glasses have been prepared. Three Judd-Ofelt parameters Ωt (t=2, 4, 6) and radiative properties are calculated for prepared glasses. Emission characteristics are analyzed and it is found that prepared glasses possess larger calculated predicted spontaneous transition probability (39....

journal_title：Scientific reports

authors： Chen F,Wei T,Jing X,Tian Y,Zhang J,Xu S

更新日期：2015-06-02 00:00:00

abstract：:We investigate the impact of borders on the topology of spatially embedded networks. Indeed territorial subdivisions and geographical borders significantly hamper the geographical span of networks thus playing a key role in the formation of network communities. This is especially important in scientific and technologi...

journal_title：Scientific reports

authors： Cerina F,Chessa A,Pammolli F,Riccaboni M

更新日期：2014-04-01 00:00:00

abstract：:X-ray diffraction, Amorphous silicon, Multi-objective optimization, Monte Carlo methods. This paper addresses a difficult inverse problem that involves the reconstruction of a three-dimensional model of tetrahedral amorphous semiconductors via inversion of diffraction data. By posing the material-structure determinati...

journal_title：Scientific reports

authors： Limbu DK,Elliott SR,Atta-Fynn R,Biswas P

更新日期：2020-05-08 00:00:00

abstract：:Genetic alterations identified in adjacent normal appearing tissue in bladder cancer patients are indicative of a field disease. Here we assessed normal urothelium transformation and intra-tumour heterogeneity (ITH) in four patients with bladder cancer. Exome sequencing identified private acquired mutations in a lymph...

journal_title：Scientific reports

authors： Thomsen MBH,Nordentoft I,Lamy P,Vang S,Reinert L,Mapendano CK,Høyer S,Ørntoft TF,Jensen JB,Dyrskjøt L

更新日期：2017-09-15 00:00:00

abstract：:In this study, we aimed to investigate the protective effects and underlying mechanism of Lycium barbarum polysaccharide (LBP) on high-fat-induced nonalcoholic fatty liver disease (NAFLD). Recently, sirtuin 1 (SIRT1) has been shown to play an important role in the regulation of hepatocellular lipid metabolism. Here, w...

journal_title：Scientific reports

authors： Jia L,Li W,Li J,Li Y,Song H,Luan Y,Qi H,Ma L,Lu X,Yang Y

更新日期：2016-11-08 00:00:00

abstract：:Spirometry is required to confirm a chronic obstructive pulmonary disease (COPD) diagnosis, but it is difficult to perform in resource-limited settings. This study aimed to evaluate symptom-based questions for screening of individuals with COPD among Chinese populations. We recruited 3969 adult subjects from the First...

journal_title：Scientific reports

authors： Zhang Q,Wang M,Li X,Wang H,Wang J

更新日期：2016-07-26 00:00:00

abstract：:Extranodal NK/T-cell lymphoma, nasal type (NKTL) is an aggressive type of non-Hodgkin lymphoma closely associated with Epstein-Barr virus and characterized by varying degrees of systemic inflammation. We aim to examine the prognostic significance of peripheral blood neutrophil-lymphocyte ratio (NLR) in patients with N...

journal_title：Scientific reports

authors： Tan KM,Chia B,Lim JQ,Khoo LP,Cheng CL,Tan L,Poon E,Somasundaram N,Farid M,Tang TPL,Tao M,Cheah DMZ,Laurensia Y,Pang JWL,Song T,Tan J,Huang D,Kim SJ,Kim WS,Ong CK,Lim ST,Chan JY

更新日期：2019-10-18 00:00:00

abstract：:The Pannexin 1 (Panx1) ion and metabolite channel is expressed in a wide variety of cells where it regulates a number of cell behaviours including proliferation and differentiation. Panx1 is expressed on the cell surface as well as intracellular membranes. Previous work suggests that a region within the proximal Panx1...

journal_title：Scientific reports

authors： Epp AL,Ebert SN,Sanchez-Arias JC,Wicki-Stordeur LE,Boyce AKJ,Swayne LA

更新日期：2019-07-05 00:00:00

abstract：:Human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) is biologically distinct from HPV-negative HNSCC. Outside of HPV-status, few tumor-intrinsic variables have been identified that correlate to improved survival. As part of exploratory analysis into the trace elemental composition of orop...

journal_title：Scientific reports

authors： Poropatich K,Paunesku T,Zander A,Wray B,Schipma M,Dalal P,Agulnik M,Chen S,Lai B,Antipova O,Maxey E,Brown K,Wanzer MB,Gursel D,Fan H,Rademaker A,Woloschak GE,Mittal BB

更新日期：2019-11-18 00:00:00

abstract：:A novel ignition hohlraum for indirect-drive inertial confinement fusion is proposed, which is named three-axis cylindrical hohlraum (TACH). TACH is a kind of 6 laser entrance holes (LEHs) hohlraum, which is orthogonally jointed of three cylindrical hohlraums. Laser beams are injected through every entrance hole with ...

journal_title：Scientific reports

authors： Kuang L,Li H,Jing L,Lin Z,Zhang L,Li L,Ding Y,Jiang S,Liu J,Zheng J

更新日期：2016-10-05 00:00:00

abstract：:Autonomic dysfunction as a partial contributing factor to cardiovascular instability in jaundiced patients is often associated with increased serum bilirubin levels. Whether increased serum bilirubin levels could directly inhibit sympathetic ganglion transmission by blocking neuronal nicotinic acetylcholine receptors ...

journal_title：Scientific reports

authors： Zhang C,Wang Z,Dong J,Pan R,Qiu H,Zhang J,Zhang P,Zheng J,Yu W

更新日期：2014-12-15 00:00:00

abstract：:Abnormal expression of microRNAs (miRNAs) contributes to glioma initiation. However, the expression of miRNAs in tumour tissue or blood of spinal cord glioma (SCG) patients, particularly in high-grade spinal gliomas (Grade IV) known as glioblastoma (GBM), remains largely unknown. In this study we aimed to determine di...

journal_title：Scientific reports

authors： An T,Fan T,Zhang XQ,Liu YF,Huang J,Liang C,Lv BH,Wang YQ,Zhao XG,Liu JX,Fu YH,Jiang GJ

更新日期：2019-06-24 00:00:00

abstract：:The influenza virus neuraminidase (NA) is essential for the virus life cycle. The rise of resistance mutations against current antiviral therapies has increased the need for the development of novel inhibitors. Recent efforts have targeted a cavity adjacent to the catalytic site (the 150-cavity) in addition to the pri...

journal_title：Scientific reports

authors： Kerry PS,Mohan S,Russell RJ,Bance N,Niikura M,Pinto BM

更新日期：2013-10-16 00:00:00

abstract：:Quantum Hall ferromagnetic transitions are typically achieved by increasing the Zeeman energy through in-situ sample rotation, while transitions in systems with pseudo-spin indices can be induced by gate control. We report here a gate-controlled quantum Hall ferromagnetic transition between two real spin states in a c...

journal_title：Scientific reports

authors： Lu TM,Tracy LA,Laroche D,Huang SH,Chuang Y,Su YH,Li JY,Liu CW

更新日期：2017-06-01 00:00:00

abstract：:Periodontal (gum) disease is a highly prevalent infection and inflammation accounting for the majority of tooth loss in adult population worldwide. Porphyromonas gingivalis is a keystone periodontal pathogen and its lipopolysaccharide (PgLPS) acts as a major virulence attribute to the disease. Herein, we deciphered th...

journal_title：Scientific reports

authors： Herath TDK,Darveau RP,Seneviratne CJ,Wang CY,Wang Y,Jin L

更新日期：2016-08-19 00:00:00

abstract：:MicroRNA-200 (miR-200) family is highly expressed in ovarian cancer. We evaluated the levels of family members relative to the internal control miR-103a in ovarian cancer and control blood specimens collected from American and Hong Kong Chinese institutions, as well as from a laying hen spontaneous ovarian cancer mode...

journal_title：Scientific reports

authors： Choi PW,Bahrampour A,Ng SK,Liu SK,Qiu W,Xie F,Kuo WP,Kwong J,Hales KH,Hales DB,Wong KK,Norwitz ER,Chow CK,Berkowitz RS,Ng SW

更新日期：2020-11-18 00:00:00

abstract：:We report localised-surface-plasmon (LSP) enhanced deep-ultraviolet light-emitting diodes (deep-UV LEDs) using Al nanoparticles for LSP coupling. Polygonal Al nanoparticles were fabricated on the top surfaces of the deep-UV LEDs using the oblique-angle deposition method. Both the top- and bottom-emission electrolumine...

journal_title：Scientific reports

authors： Huang K,Gao N,Wang C,Chen X,Li J,Li S,Yang X,Kang J

更新日期：2014-03-14 00:00:00

abstract：:Conventional effluent trading systems (ETSs) between point sources (PSs) and nonpoint sources (NPSs) are often unreliable because of the uncertain characteristics of NPSs. In this study, a new framework was established for PS-NPS ETSs, and a comprehensive analysis was conducted by quantifying the impacts of the uncert...

journal_title：Scientific reports

authors： Chen L,Han Z,Wang G,Shen Z

更新日期：2016-07-11 00:00:00

abstract：:Early fMRI studies suggested that brain areas processing self-related and other-related information were highly overlapping. Hypothesising functional localisation of the cortex, researchers have tried to locate "self-specific" and "other-specific" regions within these overlapping areas by subtracting suspected confoun...

journal_title：Scientific reports

authors： Chen YA,Huang TR

更新日期：2017-03-03 00:00:00

abstract：:Deleterious mutations in patchd1 domain containing 1 (PTCHD1) gene have been identified in patients with intellectual disability and/or autism spectrum disorder (ASD). To clarify the causal relationship between Ptchd1 deficiency and behavioral defects relevant to neurodevelopmental disorders, we generated global Ptchd...

journal_title：Scientific reports

authors： Murakami Y,Imamura Y,Saito K,Sakai D,Motoyama J

更新日期：2019-09-12 00:00:00

abstract：:Plant extracts contain many active compounds, which are tremendously fruitful for plant defence against several insect pests. The prime objectives of the present study were to calculate the extraction yield and to evaluate the leaf extracts of Citrullus colocynthis (L.), Cannabis indica (L.) and Artemisia argyi (L.) a...

journal_title：Scientific reports

authors： Ahmed M,Peiwen Q,Gu Z,Liu Y,Sikandar A,Hussain D,Javeed A,Shafi J,Iqbal MF,An R,Guo H,Du Y,Wang W,Zhang Y,Ji M

更新日期：2020-01-16 00:00:00

abstract：:The 2,5-Diketopiperazines (DKPs) constitute a large family of natural products with important biological activities. Bicyclomycin is a clinically-relevant DKP antibiotic that is the first and only member in a class known to target the bacterial transcription termination factor Rho. It derives from cyclo-(L-isoleucyl-L...

journal_title：Scientific reports

authors： Witwinowski J,Moutiez M,Coupet M,Correia I,Belin P,Ruzzini A,Saulnier C,Caraty L,Favry E,Seguin J,Lautru S,Lequin O,Gondry M,Pernodet JL,Darbon E

更新日期：2019-12-27 00:00:00

abstract：:Colors of crystals, pigments, metals, salt solutions and bioluminescence occur in nature due to the optical properties of electrons in atoms and molecules. However, colors can also result from interference effects on nanostructures. In contrast to artificial coloration, which are caused by well-defined regular structu...

journal_title：Scientific reports

authors： Zyla G,Kovalev A,Grafen M,Gurevich EL,Esen C,Ostendorf A,Gorb S

更新日期：2017-12-15 00:00:00

abstract：:The application of nitrogen (N) fertilizer deep in soil at the same time as mechanical transplanting of rice seedlings is an effective alternative to conventional broadcasting of fertilizer, but its effects on yields and profitability have not been analysed in detail. Here, we analysed the effects of a side deep appli...

journal_title：Scientific reports

authors： Zhu C,Xiang J,Zhang Y,Zhang Y,Zhu D,Chen H

更新日期：2019-04-04 00:00:00