First profiling of lysine crotonylation of myofilament proteins and ribosomal proteins in zebrafish embryos.

abstract：:Childhood and adolescent overweight and obesity are increasing in China, but limited information is available on its secular trends in Guangzhou. In this cross-sectional study, ten-wave successive data were obtained from the physical fitness surveillance for students in Guangzhou from 2003 to 2012. A total of 2,619,15...

journal_title：Scientific reports

authors： Zong Y,Xie R,Deng N,Liu L,Tan W,Gao Y,Yang J,Yang Y

更新日期：2017-09-21 00:00:00

abstract：:In this paper, we investigate the relationship between the quantum speedup, non-Markovianity and formation of a system-environment bound state. Previous results show a monotonic relation between these three such that providing bound states with more negative energy can lead to a higher degree of non-Markovianity, and ...

journal_title：Scientific reports

authors： Ahansaz B,Ektesabi A

更新日期：2019-10-18 00:00:00

abstract：:The chloride gradient plays an important role in regulating cell volume, membrane potential, pH, secretion, and the reversal potential of inhibitory glycine and GABAA receptors. Measurement of intracellular chloride activity, [Formula: see text], using liquid membrane ion-selective microelectrodes (ISM), however, has ...

journal_title：Scientific reports

authors： DiFranco M,Quinonez M,Dziedzic RM,Spokoyny AM,Cannon SC

更新日期：2019-12-11 00:00:00

abstract：:Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified as the umami (savory) taste receptor. Amino acids and 5'-ribonucleotides are well known to be natural ligands for human...

journal_title：Scientific reports

authors： Toda Y,Nakagita T,Hirokawa T,Yamashita Y,Nakajima A,Narukawa M,Ishimaru Y,Uchida R,Misaka T

更新日期：2018-08-07 00:00:00

abstract：:Acute heart failure (AHF) emerges either de novo or from worsening of chronic heart failure (CHF). The aim of the present study was to evaluate the association between worsening of CHF and mortality in AHF patients. Out of 152 included AHF patients, 47 (30.9%) were de novo AHF patients and 105 (69%) were AHF patients ...

journal_title：Scientific reports

authors： Degoricija V,Trbušić M,Potočnjak I,Radulović B,Terešak SD,Pregartner G,Berghold A,Tiran B,Frank S

更新日期：2018-06-25 00:00:00

abstract：:Experimental evidence has shown that some of the human endogenous hormones significantly affect drug efficacy. Since hormone status varies with individual physiological states, it is essential to understand the interplay of hormones and drugs for precision medicine. Here, we developed an in silico method to predict in...

journal_title：Scientific reports

authors： Kwon M,Jung J,Yu H,Lee D

更新日期：2017-11-30 00:00:00

abstract：:Climate influences vegetation directly and through climate-mediated disturbance processes, such as wildfire. Temperature and area burned are positively associated, conditional on availability of vegetation to burn. Fire is a self-limiting process that is influenced by productivity. Yet, many fire projections assume su...

journal_title：Scientific reports

authors： Hurteau MD,Liang S,Westerling AL,Wiedinmyer C

更新日期：2019-02-26 00:00:00

abstract：:Chronic pulmonary inflammation (CPI) gives rise to serious lung injuries in rheumatoid arthritis (RA) patients. However, the molecular mechanism underlying the pathogenesis of RA-associated CPI remains little understood. Here we established a novel tree shrew-based collagen-induced arthritis (TsCIA) model to study RA-...

journal_title：Scientific reports

authors： Gao B,Lin J,Jiang Z,Yang Z,Yu H,Ding L,Yu M,Cui Q,Dunavin N,Zhang M,Li M

更新日期：2018-07-03 00:00:00

abstract：:It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 twin cohorts in 15 countries derived from the COllaborative project of Development of Anthropometri...

journal_title：Scientific reports

authors： Jelenkovic A,Sund R,Yokoyama Y,Hur YM,Ullemar V,Almqvist C,Magnusson PK,Willemsen G,Bartels M,Beijsterveldt CEV,Bogl LH,Pietiläinen KH,Vuoksimaa E,Ji F,Ning F,Pang Z,Nelson TL,Whitfield KE,Rebato E,Llewellyn CH,Fi

更新日期：2018-04-19 00:00:00

abstract：:The moist savanna zone covers 0.5 × 106 km2 in West Africa and is characterized by very low soil N levels limiting primary production, but the ecology of nitrifiers in these (agro)ecosystems is largely unknown. We compared the effects of six agricultural practices on nitrifier activity, abundance and diversity at nine...

journal_title：Scientific reports

authors： Assémien FL,Pommier T,Gonnety JT,Gervaix J,Le Roux X

更新日期：2017-08-31 00:00:00

abstract：:Traumatic brain injury (TBI) is a risk factor for Alzheimer's disease (AD), although the mechanisms contributing to this increased risk are unknown. Insulin resistance is an additional risk factor for AD whereby decreased insulin signaling increases synaptic sensitivity to amyloid beta (Aβ) and tau. Considering this, ...

journal_title：Scientific reports

authors： Franklin W,Krishnan B,Taglialatela G

更新日期：2019-06-03 00:00:00

abstract：:Gyroviruses (GyVs) are small, single-stranded, circular DNA viruses in the genus Gyrovirus, which consists of the chicken anemia virus (CAV) prototype and nine other viral species. These different GyV species have been reported in chickens, humans, mice, and companion animals. To date, CAV has been identified in the f...

journal_title：Scientific reports

authors： Niu JT,Yi SS,Dong GY,Guo YB,Zhao YL,Huang HL,Wang K,Hu GX,Dong H

更新日期：2019-09-16 00:00:00

abstract：:Here we present spatio-temporal localization of Kremen1, a transmembrane receptor, in the mammalian cochlea, and investigate its role in the formation of sensory organs in mammal and fish model organisms. We show that Kremen1 is expressed in prosensory cells during cochlear development and in supporting cells of the a...

journal_title：Scientific reports

authors： Mulvaney JF,Thompkins C,Noda T,Nishimura K,Sun WW,Lin SY,Coffin A,Dabdoub A

更新日期：2016-08-23 00:00:00

abstract：:As any cognitive task, visual search involves a number of underlying processes that cannot be directly observed and measured. In this way, the movement of the eyes certainly represents the most explicit and closest connection we can get to the inner mechanisms governing this cognitive activity. Here we show that the p...

journal_title：Scientific reports

authors： Amor TA,Reis SD,Campos D,Herrmann HJ,Andrade JS Jr

更新日期：2016-02-11 00:00:00

abstract：:Modic change (MC) is considered an independent risk factor for low back pain (LBP) but its aetiology remains unclear. In this cross-sectional, large-scale population-based study we sought to characterise associations between endplate defect (ED) and MC in a population sample of broad age range. The study population co...

journal_title：Scientific reports

authors： Määttä JH,Rade M,Freidin MB,Airaksinen O,Karppinen J,Williams FMK

更新日期：2018-11-09 00:00:00

abstract：:Proteasome inhibition represents an important anticancer strategy. Here, we studied the mechanisms at the basis of the pro-apoptotic activity of the standardized decoction of Hemidesmus indicus, a plant evoking a complex anticancer activity, and explored its inhibition of proteasome activity in human leukemia cells. A...

journal_title：Scientific reports

authors： Turrini E,Catanzaro E,Ferruzzi L,Guerrini A,Tacchini M,Sacchetti G,Paganetto G,Maffei F,Pellicioni V,Poli F,Hrelia P,Mandrone M,Sestili P,Brigotti M,Fimognari C

更新日期：2019-05-10 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Thomas D,Bagiya MS,Sunil PS,Rolland L,Sunil AS,Mikesell TD,Nayak S,Mangalampalli S,Ramesh DS

更新日期：2018-11-01 00:00:00

abstract：:Increasing evidence suggest that the glucose-lowering drug metformin exerts a valuable anti-senescence role. The ability of metformin to affect the biogenesis of selected microRNAs (miRNAs) was recently suggested. MicroRNA isoforms (isomiRs) are distinct variations of miRNA sequences, harboring addition or deletion of...

journal_title：Scientific reports

authors： Giuliani A,Londin E,Ferracin M,Mensà E,Prattichizzo F,Ramini D,Marcheselli F,Recchioni R,Rippo MR,Bonafè M,Rigoutsos I,Olivieri F,Sabbatinelli J

更新日期：2020-12-11 00:00:00

abstract：:Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructive role in attachin...

journal_title：Scientific reports

authors： Siu GK,Zhou F,Yu MK,Zhang L,Wang T,Liang Y,Chen Y,Chan HC,Yu S

更新日期：2016-03-24 00:00:00

abstract：:This paper portrays the dynamics of pine wilt disease. The specific formula for reproduction number is accomplished. Global behavior is completely demonstrated on the basis of the basic reproduction number [Formula: see text]. The disease-free equilibrium is globally asymptotically stable for [Formula: see text] and i...

journal_title：Scientific reports

authors： Ozair M,Hussain T,Awan AU,Aslam A,Khan RA,Ali F,Tasneem F

更新日期：2020-02-26 00:00:00

abstract：:Head and neck cancer is the sixth most common malignancy worldwide, predominantly developing from squamous cell epithelia (HNSCC). The main HNSCC risk factors are tobacco, excessive alcohol use, and the presence of human papillomavirus (HPV). HPV positive (+) cancers are etiologically different from other HNSCC and of...

journal_title：Scientific reports

authors： Božinović K,Sabol I,Dediol E,Milutin Gašperov N,Manojlović S,Vojtechova Z,Tachezy R,Grce M

更新日期：2019-02-19 00:00:00

abstract：:Irreversible electroporation (IRE) as a non-thermal tumor ablation technology has been studied for the treatment of pancreatic carcinoma and has shown a significant survival benefit. We discovered that moderate heating (MH) at 43 °C for 1-2 minutes significantly enhanced ex vivo IRE tumor ablation of Pan02 cells by 5....

journal_title：Scientific reports

authors： Edelblute CM,Hornef J,Burcus NI,Norman T,Beebe SJ,Schoenbach K,Heller R,Jiang C,Guo S

更新日期：2017-09-18 00:00:00

abstract：:We investigated the metabolic outcome of different coping strategies in 129S6/SvEvTac (129Sv) and C57BL/6Ntac (Bl6) strains. Two different batches of male 129Sv and Bl6 mice were used. One batch was not subjected to any behavioral manipulations (home cage control; HCC), whereas the other batch was treated with saline ...

journal_title：Scientific reports

authors： Narvik J,Vanaveski T,Innos J,Philips MA,Ottas A,Haring L,Zilmer M,Vasar E

更新日期：2018-02-21 00:00:00

abstract：:Up to 30% of all breast cancer cases may be inherited and up to 85% of those may be due to segregation of susceptibility genes with low and moderate risk [odds ratios (OR) ≤ 3] for (mostly peri- and post-menopausal) breast cancer. The majority of low/moderate-risk genes, particularly those with minor allele frequencie...

journal_title：Scientific reports

authors： Moslehi R,Tsao HS,Zeinomar N,Stagnar C,Fitzpatrick S,Dzutsev A

更新日期：2020-12-04 00:00:00

abstract：:Myocardial infarction (MI) can result in sympathetic nerve loss in the infarct region. However, the contribution of hypo-innervation to electrophysiological remodeling, independent from MI-induced ischemia and fibrosis, has not been comprehensively investigated. We present a novel mouse model of regional cardiac sympa...

journal_title：Scientific reports

authors： Tapa S,Wang L,Francis Stuart SD,Wang Z,Jiang Y,Habecker BA,Ripplinger CM

更新日期：2020-11-02 00:00:00

abstract：:Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to muscle hypertrophy or double-muscled (DM) phenotype in cattle, sheep, dog and human. However, there has not been reported significant muscle phenotypes in pigs in association with MSTN mutations. Pigs...

journal_title：Scientific reports

authors： Qian L,Tang M,Yang J,Wang Q,Cai C,Jiang S,Li H,Jiang K,Gao P,Ma D,Chen Y,An X,Li K,Cui W

更新日期：2015-09-24 00:00:00

abstract：:Three carbapenem-resistant Escherichia coli were recovered from rectal swabs of different patients in a tertiary hospital and were found carrying bla NDM-4, an uncommon bla NDM variant. Genome sequences of the isolates were obtained using Illumina technology and the long-read MinION sequencer. The isolates belonged to...

journal_title：Scientific reports

authors： Zhang X,Feng Y,Zhou W,McNally A,Zong Z

更新日期：2018-01-10 00:00:00

abstract：:This article reports preparation of a crosslinked polydimethylsiloxane (PDMS) network via dynamic transesterification reaction between PDMS-diglycidyl ether and pripol 1017 with Zn(OAc)2 as the catalyst. The thermal dynamic nature of the network was investigated by the creep-recovery and stress-relaxation tests. The s...

journal_title：Scientific reports

authors： Zhang H,Cai C,Liu W,Li D,Zhang J,Zhao N,Xu J

更新日期：2017-09-19 00:00:00

abstract：:Little-Parks effect names the oscillations in the superconducting critical temperature as a function of the magnetic field. This effect is related to the geometry of the sample. In this work, we show that this effect can be enhanced and manipulated by the inclusion of magnetic nanostructures with perpendicular magneti...

journal_title：Scientific reports

authors： de Ory MC,Rollano V,Gomez A,Menghini M,Muñoz-Noval A,Gonzalez EM,Vicent JL

更新日期：2020-06-25 00:00:00

abstract：:The increasing demands in security and reliability of infrastructures call for the optimal design of their embedded complex networks topologies. The following question then arises: what is the optimal layout to fulfill best all the demands? Here we present a general solution for this problem with scale-free networks, ...

journal_title：Scientific reports

authors： Sampaio Filho CI,Moreira AA,Andrade RF,Herrmann HJ,Andrade JS Jr

更新日期：2015-03-13 00:00:00