Abstract：
:There have been significant developments in Ebola virus therapeutics. While the efficacy of several products was evaluated in the recent West Africa outbreak, a licensed treatment for EBOV disease remains elusive. Factors that negatively impacted the execution of clinical trials included an overall lack of world readiness to conduct clinical trials in an outbreak setting, ethical concerns limiting implementation of the randomized controlled trials in an outbreak setting, and a decline in case numbers by the time resources were mobilized to conduct clinical trials. We summarize relevant therapeutics that underwent clinical trials during the West Africa outbreak and highlight promising candidates under advanced development.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Cardile AP,Downey LG,Wiseman PD,Warren TK,Bavari Sdoi
10.1016/j.coph.2016.08.016subject
Has Abstractpub_date
2016-10-01 00:00:00pages
138-143eissn
1471-4892issn
1471-4973pii
S1471-4892(16)30105-9journal_volume
30pub_type
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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journal_title：Current opinion in pharmacology
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