Abstract：
:Following the fate of antigen-specific memory B cells has been difficult. In this issue of Immunity, Krishnamurty et al. (2016) use a novel B cell tetramer to define Plasmodium-specific memory B cells in parasite-infected mice and demonstrate that after re-infection, somatically mutated IgM(+) memory B cells function as first responders by rapidly differentiating into T-cell-dependent plasmablasts and T-cell-independent plasma cells.
journal_name
Immunityjournal_title
Immunityauthors
Stone SL,Lund FEdoi
10.1016/j.immuni.2016.08.005subject
Has Abstractpub_date
2016-08-16 00:00:00pages
235-7issue
2eissn
1074-7613issn
1097-4180pii
S1074-7613(16)30306-5journal_volume
45pub_type
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