Activity-dependent synapse to nucleus signaling.

abstract：:Rodents exhibit neophobia for novel tastes, demonstrated by an initial reluctance to drink novel-tasting, potentially-aversive solutions. Taste neophobia attenuates across days if the solution is not aversive, demonstrated by increased consumption as the solution becomes familiar. This attenuation of taste neophobia i...

journal_title：Neurobiology of learning and memory

authors： Grau-Perales AB,Levy ERJ,Fenton AA,Gallo M

更新日期：2019-01-01 00:00:00

abstract：:Mitogen-activated protein kinase (MAPK) is abundantly expressed in postmitotic neurons of the developed nervous system. MAPK is activated and required for induction of long-term potentiation (LTP) in the CA1 area of the hippocampus, which is blocked by the specific inhibitor of the MAPK kinase, PD 098059. Recently it ...

journal_title：Neurobiology of learning and memory

authors： Walz R,Roesler R,Quevedo J,Sant'Anna MK,Madruga M,Rodrigues C,Gottfried C,Medina JH,Izquierdo I

更新日期：2000-01-01 00:00:00

abstract：:Renewal, or reinstatement, of responding to food cues after extinction may explain the inability to resist palatable foods and change maladaptive eating habits. Previously, we found sex differences in context-dependent renewal of extinguished Pavlovian conditioned responding to food cues. Context-induced renewal invol...

journal_title：Neurobiology of learning and memory

authors： Anderson LC,Petrovich GD

更新日期：2017-03-01 00:00:00

abstract：:Male songbirds learn to produce song within a limited phase early in life; however they continue to learn to recognize songs in adulthood. Studies looking at Zenk activation after exposure to songs learned early in life for song production and songs learned in adulthood show opposite patterns of activation, suggesting...

journal_title：Neurobiology of learning and memory

authors： McKenzie TL,Hernandez AM,MacDougall-Shackleton SA

更新日期：2006-11-01 00:00:00

abstract：:The present study investigated whether the selective nociceptin opioid peptide (NOP) receptor agonist, Ro64-6198, impairs acquisition of fear conditioning through glutamatergic mechanisms. Systemic administration of Ro64-6198 (0.3 and 1mg/kg) or the non-competitive NMDA receptor antagonist, MK-801 (0.03 and 0.1mg/kg) ...

journal_title：Neurobiology of learning and memory

authors： Goeldner C,Reiss D,Wichmann J,Kieffer BL,Ouagazzal AM

更新日期：2009-05-01 00:00:00

abstract：:Several studies using inhibitory avoidance models have demonstrated the importance of limbic structures, such as the amygdala, dorsal hippocampus and medial prefrontal cortex, in the consolidation of emotional memory. However, we aimed to investigate the role of the amygdala (AMG), dorsal hippocampus (DH) and medial p...

journal_title：Neurobiology of learning and memory

authors： Canto-de-Souza L,Mattioli R

更新日期：2016-04-01 00:00:00

abstract：:The specific sigma-receptor agonist (+)-SKF 10047 and antagonist BD 1047 were used to investigate whether this receptor was involved in passive-avoidance training in the day-old chick. We found 300 microM (+)-SKF 10047 to be amnesic when injected into the lobus parolfactorius 5 h after training (p < .01). Higher or lo...

journal_title：Neurobiology of learning and memory

authors： Freeman FM,Young IG

更新日期：2001-05-01 00:00:00

abstract：:Research on how steroid hormones mediate mnemonic processes have focused on effects of 17beta-estradiol (E(2)); yet, progesterone (P(4)) co-varies with E(2) across endogenous hormonal milieu, and itself may influence cognitive processes. We investigated the hypothesis that acute P(4) treatment enhances cognitive perfo...

journal_title：Neurobiology of learning and memory

authors： Frye CA,Walf AA

更新日期：2008-07-01 00:00:00

abstract：:Every learning event is embedded in a context, but not always does the context become an integral part of the memory; however, for extinction learning it usually does, resulting in context-specific conditioned responding. The neuronal mechanisms underlying contextual control have been mainly investigated for Pavlovian...

journal_title：Neurobiology of learning and memory

authors： Starosta S,Bartetzko I,Stüttgen MC,Güntürkün O

更新日期：2017-10-01 00:00:00

abstract：:Spatial working memory and the ability of a cholinesterase inhibitor to enhance memory were assessed at 4, 10, and 16 months of ages in control and Ts65Dn mice, a partial trisomy model of Down syndrome, with possibly significant relationships to Alzheimer's disease as well. In addition, ACh release during memory testi...

journal_title：Neurobiology of learning and memory

authors： Chang Q,Gold PE

更新日期：2008-02-01 00:00:00

abstract：:Extensive evidence indicates that benzodiazepine receptors in the amygdala are involved in regulating memory consolidation. Recent findings indicate that many other drugs and hormones influence memory through selective activation of the basolateral amygdala nucleus (BLA). This experiment examined whether the memory-mo...

journal_title：Neurobiology of learning and memory

authors： Da Cunha C,Roozendaal B,Vazdarjanova A,McGaugh JL

更新日期：1999-07-01 00:00:00

abstract：:The authors evaluate a mapping of Rescorla and Wagner's (1972) behavioral model of classical conditioning onto the cerebellar substrates for motor reflex learning and illustrate how the limitations of the Rescorla-Wagner model are just as useful as its successes for guiding the development of new psychobiological theo...

journal_title：Neurobiology of learning and memory

authors： Gluck MA,Allen MT,Myers CE,Thompson RF

更新日期：2001-11-01 00:00:00

abstract：:Several lines of evidence indicate that gamma-aminobutyric acid (GABA) type A (GABA(A)) receptors regulate memory consolidation. Here we studied the effect on consolidation of the selective antagonist of GABA(A) receptors, bicuculline, given into several regions of the cortex at different times after one-trial step-do...

journal_title：Neurobiology of learning and memory

authors： Luft T,Pereira GS,Cammarota M,Izquierdo I

更新日期：2004-07-01 00:00:00

abstract：:The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) affects numerous behavioral and physiological processes. Drugs that alter 5-HT signaling treat several major psychiatric disorders and may lead to widespread abuse. The dorsal raphe nucleus (DRN) in the midbrain provides a majority of 5-HT for the forebrain. T...

journal_title：Neurobiology of learning and memory

authors： Luo M,Li Y,Zhong W

更新日期：2016-11-01 00:00:00

abstract：:Most models of human and animal learning assume that learning is proportional to the discrepancy between a delivered outcome and the outcome predicted by all cues present during that trial (i.e., total error across a stimulus compound). This total error reduction (TER) view has been implemented in connectionist and ar...

journal_title：Neurobiology of learning and memory

authors： Witnauer JE,Urcelay GP,Miller RR

更新日期：2014-02-01 00:00:00

abstract：:Electrolytic lesions centered on the amygdaloid central nucleus (ACe) resulted in the inability of rats to acquire a Pavlovian conditional vocalization response. Conditioning consisted of pairing a light conditional stimulus with a tailshock unconditional stimulus (US). The thresholds of three unconditional responses ...

journal_title：Neurobiology of learning and memory

authors： Borszcz GS,Leaton RN

更新日期：2003-05-01 00:00:00

abstract：:Adult Aplysia exhibit both short-term and long-term memory for sensitization in the gill and siphon withdrawal reflex. Previous developmental studies showed that short-term memory for sensitization emerges late in juvenile development (stage 12; Rankin and Carew, 1988; Wright et al., 1991). In the present study, we ex...

journal_title：Neurobiology of learning and memory

authors： Wright WG,McCance EF,Carew TJ

更新日期：1996-05-01 00:00:00

abstract：:In a previous study, we found that in contrast to healthy controls, hydrocortisone administration had enhancing effects on memory in patients with borderline personality disorder (BPD). Because hydrocortisone acts on glucocorticoid receptors (GR) and mineralocorticoid receptors (MR), it is unclear which receptor media...

journal_title：Neurobiology of learning and memory

authors： Wingenfeld K,Kuehl LK,Janke K,Hinkelmann K,Eckert FC,Roepke S,Otte C

更新日期：2015-04-01 00:00:00

abstract：:The prefrontal cortex is known to be involved in the acquisition of trace conditioning, a higher-cognitive form of Pavlovian conditioning in which a conditioned stimulus and an unconditioned stimulus are separated by a time gap. We have recently reported that medial prefrontal (mPFC) extracellular-signal regulated kin...

journal_title：Neurobiology of learning and memory

authors： Runyan JD,Dash PK

更新日期：2004-09-01 00:00:00

abstract：:Neuroplastin 65 (NP65) is a brain-specific glycoprotein component of synaptic membrane, which is predominantly located in the forebrain such as the cortex, amygdala and striatum and hippocampus. Previous studies have shown that NP65 is implicated in synaptic plasticity, so it was hypothesized to play roles in cognitiv...

journal_title：Neurobiology of learning and memory

authors： Amuti S,Tang Y,Wu S,Liu L,Huang L,Zhang H,Li H,Jiang F,Wang G,Liu X,Yuan Q

更新日期：2016-01-01 00:00:00

abstract：:Memories for daily events require that individuals integrate initial fragile traces of events over time. Recent evidence suggests that reward anticipation enhances memory performance and amplifies frontal theta activity for remembered items vs. forgotten items. However, little is known about how incidental rewards aft...

journal_title：Neurobiology of learning and memory

authors： Pu M,Yu R

更新日期：2019-02-01 00:00:00

abstract：:The impact of past history on behavior across the life span is largely unknown. This is why the role of previous experience in subsequent memory performances has been studied in a combined longitudinal (animals repeatedly tested) and cross-sectional (animals tested once at various ages) study, in male Sprague-Dawley r...

journal_title：Neurobiology of learning and memory

authors： Dellu F,Mayo W,Vallee M,Le Moal M,Simon H

更新日期：1997-03-01 00:00:00

abstract：:It is currently well established that the synthesis of new proteins (mRNA translation) is required for long-lasting synaptic plasticity and memory formation. Translation in the brain is regulated primarily at the initiation stage by general as well as by gene-specific mechanisms. Stored memories can become sensitive t...

journal_title：Neurobiology of learning and memory

authors： Roesler R

更新日期：2017-07-01 00:00:00

abstract：:Synaptic plasticity is subject to activity-dependent long-term modification (metaplasticity). We have recently described a novel form of heterosynaptic metaplasticity in hippocampal CA1, whereby 'priming' activity at one set of synapses confers a metaplastic state that inhibits subsequent LTP both within and between d...

journal_title：Neurobiology of learning and memory

authors： Jones OD,Hulme SR,Abraham WC

更新日期：2013-10-01 00:00:00

abstract：:Appetitive trace conditioning (TC) was examined over 6 months in younger-adult (2-8 months) and middle-aged (12-18 months) male Wistar RccHan rats, to test for early age-related impairment in working memory. Novel object recognition (NOR) was included as a comparison task, to provide a positive control in the event th...

journal_title：Neurobiology of learning and memory

authors： Marshall HJ,Pezze MA,Fone KCF,Cassaday HJ

更新日期：2019-10-01 00:00:00

abstract：:New neurons are continually produced in the adult mammalian brain from progenitor cells located in specific brain regions, including the subgranular zone (SGZ) of the dentate gyrus of the hippocampus. We hypothesized that neurogenesis occurs in the canine brain and is reduced with age. We examined neurogenesis in the ...

journal_title：Neurobiology of learning and memory

authors： Siwak-Tapp CT,Head E,Muggenburg BA,Milgram NW,Cotman CW

更新日期：2007-09-01 00:00:00

abstract：:Both the acquisition and the extinction of memories leave short- and long-term mnemonic traces. Here, we show that in male Wistar rats, the short-term memory for a step-down inhibitory avoidance task (IA) is resistant to extinction, and that its expression does not influence retrieval or extinction of long-term memory...

journal_title：Neurobiology of learning and memory

authors： Cammarota M,Bevilaqua LR,Rossato JI,Ramirez M,Medina JH,Izquierdo I

更新日期：2005-07-01 00:00:00

abstract：:Addiction is increasingly discussed asa disorder of associative learning processes, with both operant and classical conditioning contributing to the development of maladaptive habits. Stress has long been known to promote drug taking and relapse and has further been shown to shift behavior from goal-directed actions t...

journal_title：Neurobiology of learning and memory

authors： Ehlers MR,Todd RM

更新日期：2017-11-01 00:00:00

abstract：:Based on computational models of the hippocampus, it has been suggested that a possible mechanism for memory retrieval is pattern completion, wherein an autoassociative network recalls previous patterns of activity given noisy or degraded cues. However, there are few behavioral data examining pattern completion per se...

journal_title：Neurobiology of learning and memory

authors： Kirwan CB,Gilbert PE,Kesner RP

更新日期：2005-01-01 00:00:00

abstract：:While sleep's role in emotional memory processing is gaining increasing support, its effect on emotion regulation remains equivocal. Moreover, little is known about the link between emotional reactivity at the time of encoding and subsequent sleep-based emotional memory consolidation. This study examined whether sleep...

journal_title：Neurobiology of learning and memory

authors： Cunningham TJ,Crowell CR,Alger SE,Kensinger EA,Villano MA,Mattingly SM,Payne JD

更新日期：2014-10-01 00:00:00