The effect of amygdala lesions on conditional and unconditional vocalizations in rats.

abstract：:Animals tend to repeat actions that are associated with reward delivery, whereas they tend to shift responses to alternate choices following reward omission. These so-called win-stay and lose-shift responses are employed by a wide range of animals in a variety of decision-making scenarios, and depend on dissociated re...

journal_title：Neurobiology of learning and memory

authors： Thapa R,Gruber AJ

更新日期：2018-11-01 00:00:00

abstract：:Differences in cytoarchitectural organization and connectivity distinguishes granular (or area 29, A29) and dysgranular (or area 30, A30) subdivisions of the retrosplenial cortex (RSC). Although increasing evidence supports the participation of RSC in contextual fear learning and memory, the contribution of each RSC s...

journal_title：Neurobiology of learning and memory

authors： Sigwald EL,de Olmos S,Lorenzo A

更新日期：2020-05-01 00:00:00

abstract：:In insects, cholinergic neurons are thought to transmit olfactory conditioned stimulus (CS) to the sites for associating the CS with unconditioned stimulus (US), but the types of acetylcholine (ACh) receptor used by neurons participating in the association have not been determined. In cockroaches, a type of nicotinic ...

journal_title：Neurobiology of learning and memory

authors： Watanabe H,Matsumoto CS,Nishino H,Mizunami M

更新日期：2011-01-01 00:00:00

abstract：:The effects of selective cholinergic cell loss within the basal forebrain (BF) were determined using a task that requires shifting of attention between two visual stimuli. Discriminability between two stimuli and response bias were determined in young and old F-344 rats given BF injections of IgG-192 saporin (100 ng)....

journal_title：Neurobiology of learning and memory

authors： Stoehr JD,Mobley SL,Roice D,Brooks R,Baker LM,Wiley RG,Wenk GL

更新日期：1997-05-01 00:00:00

abstract：:Individual differences in regulation of fear and extinction memory play significant roles in the aetiology development of post-traumatic stress disorder (PTSD). Previous animal based studies showed that the activity of β-adrenergic receptors (β-ARs) are involved in memory modulation. However in humans it is not clear ...

journal_title：Neurobiology of learning and memory

authors： Shi L,Chen SJ,Deng JH,Que JY,Lin X,Sun Y,Bao YP,Shi J,Lu L

更新日期：2018-12-01 00:00:00

abstract：:Although everyone would agree that successful translation of therapeutic candidates for central nervous disorders should involve non-human primate (nhp) models of cognitive disorders, we are left with the paucity of publications reporting either the target validation or the actual preclinical testing in heuristic nhp ...

journal_title：Neurobiology of learning and memory

authors： Camus S,Ko WK,Pioli E,Bezard E

更新日期：2015-10-01 00:00:00

abstract：:The article reviews our studies of contextual fear conditioning (CFC) in rats during a period of development---Postnatal Day (PND) 17-33---that represents the late-infant, juvenile, and early-adolescent stages. These studies seek to acquire 'systems level' knowledge of brain and memory development and apply it to a ro...

journal_title：Neurobiology of learning and memory

authors： Stanton ME,Murawski NJ,Jablonski SA,Robinson-Drummer PA,Heroux NA

更新日期：2021-01-19 00:00:00

abstract：:Drug addiction can be understood as a pathological subversion of normal brain learning and memory processes strengthened by the motivational impact of drug-associated stimuli, leading to the establishment of compulsive drug-seeking habits. Such habits evolve through a cascade of complex associative processes with Pavl...

journal_title：Neurobiology of learning and memory

authors： Robbins TW,Everitt BJ

更新日期：2002-11-01 00:00:00

abstract：:It has been known for a long time that cholinergic basal forebrain neurons which project to the cerebral cortex play a role in learning and memory. Behavioral studies following lesions, for example, repeatedly have suggested multiple learning-related roles for these neurons. Apart from behavioral studies, cholinergic ...

journal_title：Neurobiology of learning and memory

authors： Woolf NJ

更新日期：1996-11-01 00:00:00

abstract：:Accumulating evidence indicates that homeostatic plasticity mechanisms dynamically adjust synaptic strength to promote stability that is crucial for memory storage. Our previous studies have shown that prior training in conditioned taste aversion (CTA) prevents the subsequent induction of long-term potentiation (LTP) ...

journal_title：Neurobiology of learning and memory

authors： Rivera-Olvera A,Nelson-Mora J,Gonsebatt ME,Escobar ML

更新日期：2018-10-01 00:00:00

abstract：:Primary sensory cortical fields develop highly specific associative representational plasticity, notably enlarged area of representation of reinforced signal stimuli within their topographic maps. However, overtraining subjects after they have solved an instrumental task can reduce or eliminate the expansion while the...

journal_title：Neurobiology of learning and memory

authors： Elias GA,Bieszczad KM,Weinberger NM

更新日期：2015-12-01 00:00:00

abstract：:The objective of the present study was to observe the effects of pre-training or post-training administration of dicyclomine, a M1 muscarinic antagonist, on inhibitory avoidance (IA) and contextual fear conditioning (CFC) and to investigate if the effects observed with the pre-training administration of dicyclomine ar...

journal_title：Neurobiology of learning and memory

authors： Soares JC,Fornari RV,Oliveira MG

更新日期：2006-09-01 00:00:00

abstract：:Environmental stimuli during neonatal periods play an important role in the development of cognitive function. In this study, we examined the long-term effects of neonatal tactile stimulation (TS) on spatial working memory (SWM) and related mechanisms. We also investigated whether TS-induced effects could be counterac...

journal_title：Neurobiology of learning and memory

authors： Zhang M,Cai JX

更新日期：2008-05-01 00:00:00

abstract：:Traditional learning theory has developed models that can accurately predict and describe the course of learned behavior. These "psychological process" models rely on hypothetical constructs that are usually thought to be not directly measurable or manipulable. Recently, and mostly in parallel, the neural mechanisms u...

journal_title：Neurobiology of learning and memory

authors： Fanselow MS,Zelikowsky M,Perusini J,Barrera VR,Hersman S

更新日期：2014-02-01 00:00:00

abstract：:Phosphodiesterase inhibitors (PDE-Is) enhance cAMP and/or cGMP signaling via reducing the degradation of these cyclic nucleotides. Both cAMP and cGMP signaling are essential for a variety of cellular functions and exert their effects both pre- and post-synaptically. Either of these second messengers relays and amplifi...

journal_title：Neurobiology of learning and memory

authors： Heckman PR,Blokland A,Ramaekers J,Prickaerts J

更新日期：2015-03-01 00:00:00

abstract：:The impact of past history on behavior across the life span is largely unknown. This is why the role of previous experience in subsequent memory performances has been studied in a combined longitudinal (animals repeatedly tested) and cross-sectional (animals tested once at various ages) study, in male Sprague-Dawley r...

journal_title：Neurobiology of learning and memory

authors： Dellu F,Mayo W,Vallee M,Le Moal M,Simon H

更新日期：1997-03-01 00:00:00

abstract：:The therapeutic efficacy of the synthetic β-adrenergic receptor blocker, propranolol, for the treatment of post-traumatic stress disorder (PTSD) is currently being debated. Mixed results have been published regarding propranolol's ability to disrupt the consolidation and reconsolidation of memories. Here, we use the i...

journal_title：Neurobiology of learning and memory

authors： Shymansky T,Hughes E,Rothwell CM,Lukowiak K

更新日期：2018-03-01 00:00:00

abstract：:It has been well established that moderate physiological or emotional arousal modulates memory. However, there is some controversy about whether the source of arousal must be semantically related to the information to be remembered. To test this idea, 35 healthy young adult participants learned a list of common nouns ...

journal_title：Neurobiology of learning and memory

authors： Nielson KA,Yee D,Erickson KI

更新日期：2005-07-01 00:00:00

abstract：:Mitogen-activated protein kinase (MAPK) is abundantly expressed in postmitotic neurons of the developed nervous system. MAPK is activated and required for induction of long-term potentiation (LTP) in the CA1 area of the hippocampus, which is blocked by the specific inhibitor of the MAPK kinase, PD 098059. Recently it ...

journal_title：Neurobiology of learning and memory

authors： Walz R,Roesler R,Quevedo J,Sant'Anna MK,Madruga M,Rodrigues C,Gottfried C,Medina JH,Izquierdo I

更新日期：2000-01-01 00:00:00

abstract：:Activation of N-methyl-d-aspartate (NMDA) receptors has been hypothesized to mediate certain forms of learning and memory. This hypothesis is based on the ability of competitive and uncompetitive NMDA receptor antagonists to disrupt learning. We investigated the effects of glycine site antagonists and partial agonists...

journal_title：Neurobiology of learning and memory

authors： Viu E,Zapata A,Capdevila J,Skolnick P,Trullas R

更新日期：2000-09-01 00:00:00

abstract：:Neuronal plasticity and neurogenesis occur in the adult hippocampus and in other brain structures such as the olfactory bulb and often involve the neural cell adhesion molecule NCAM. During an olfactory associative discrimination learning task, NCAM polysialylation triggers neuronal plasticity in the adult hippocampus...

journal_title：Neurobiology of learning and memory

authors： Mione J,Manrique C,Duhoo Y,Roman FS,Guiraudie-Capraz G

更新日期：2016-04-01 00:00:00

abstract：:The dynamics of learning in the Active Avoidance test was analyzed at the trials level as well as at the level of daily sessions, each comprising numerous trials. The two scales (large scale for the sessions and small scale for the trials) were demonstrated to be mutually independent. The intermediate derived scales (...

journal_title：Neurobiology of learning and memory

authors： Giuliani A,Mancini AM,Ghirardi O,Ramacci MT,Voronina T,Sirabella P,Colosimo A

更新日期：1996-01-01 00:00:00

abstract：:Conditioning-specific reflex modification (CRM) of the rabbit's nictitating membrane response (NMR) involves changes in responding to an unconditioned stimulus (US) when the US is tested in the absence of the conditioned stimulus. Previous experiments have shown that CRM is a function of the type and intensity of the ...

journal_title：Neurobiology of learning and memory

authors： Schreurs BG,Smith-Bell CA

更新日期：2005-09-01 00:00:00

abstract：:The efficacy of synaptic transmission between two neurons changes as a function of the history of previous activations of the synaptic connection. This history dependence can be characterized by examining the dependence of transmission on the frequency of stimulation. In this framework synaptic plasticity can also be ...

journal_title：Neurobiology of learning and memory

authors： Markram H,Gupta A,Uziel A,Wang Y,Tsodyks M

更新日期：1998-07-01 00:00:00

abstract：:It is well established that D-cycloserine (DCS), a partial agonist of the NMDA receptor glycine site, enhances learning and memory processes. Although the effects of DCS have been especially elucidated in the extinction and reconsolidation of aversive behavioral paradigms or drug-related behaviors, they have not been ...

journal_title：Neurobiology of learning and memory

authors： Portero-Tresserra M,Martí-Nicolovius M,Guillazo-Blanch G,Boadas-Vaello P,Vale-Martínez A

更新日期：2013-02-01 00:00:00

abstract：:The amygdala, medial hypothalamus, dorsal periaqueductal gray (dPAG), superior and inferior colliculus together constitutes the encephalic aversion system which has been considered the main neural substrate for the integration of unconditioned aversive behavioral states. Within the amygdala the basolateral nucleus (BL...

journal_title：Neurobiology of learning and memory

authors： Carvalho MC,Santos JM,Bassi GS,Brandão ML

更新日期：2013-05-01 00:00:00

abstract：:Cerebellar damage occurs during developmental stages in three mutant mice (staggerer, hot-foot, and lurcher), causing disturbances in posture and equilibrium. During three tests of motor coordination, the performances of staggerer mutants was inferior to that of normal mice and did not improve with extended practice f...

journal_title：Neurobiology of learning and memory

authors： Lalonde R,Filali M,Bensoula AN,Lestienne F

更新日期：1996-03-01 00:00:00

abstract：:In this study, we evaluated the effects of NMDA-induced lesions in different sites of the insular cortex of the rat on the acquisition of conditioned taste aversion and spatial learning in the Morris water maze. The lesions were produced by bilateral microinjections of NMDA in the insular cortex at +3.7 mm (Anterior g...

journal_title：Neurobiology of learning and memory

authors： Nerad L,Ramírez-Amaya V,Ormsby CE,Bermúdez-Rattoni F

更新日期：1996-07-01 00:00:00

abstract：:Although no single widely accepted animal model of PTSD has been established to date, the single prolonged stress (SPS) animal model has been partially validated as a model for PTSD. SPS rats mimic the pathophysiological abnormalities and behavioral characteristics of PTSD, such as enhanced fear response to the trauma...

journal_title：Neurobiology of learning and memory

authors： Mirshekar M,Abrari K,Goudarzi I,Rashidy-Pour A

更新日期：2013-05-01 00:00:00

abstract：:Human studies of sleep and cognition have established thatdifferent sleep stages contribute to distinct aspects of cognitive and emotional processing. However, since the majority of these findings are based on single-night studies, it is difficult to determine whether such effects arise due to individual, between-subj...

journal_title：Neurobiology of learning and memory

authors： Lerner I,Lupkin SM,Corter JE,Peters SE,Cannella LA,Gluck MA

更新日期：2016-10-01 00:00:00