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Bulk, surface and blood-contacting properties of polyether polyurethanes modified with polydimethylsiloxane macroglycols.

Abstract：

:The bulk, surface and blood-contacting properties of a series of polyether polyurethanes, modified with three different polydimethylsiloxane (PDMS) macroglycol segments, were evaluated. The PDMS oligomers were terminated with hydroxy-tipped end groups of varying polarity. The effect of substituting the polytetramethylene oxide (PTMO) soft segment of a base polyurethane with 5 and 15 wt% of these PDMS-containing polyols was investigated. The ultimate tensile strength and elongation at break appeared to be the bulk properties most significantly affected by the addition of the PDMS-containing polyols. Underwater contact angle data indicate that the block copolymer surface became more hydrophilic with increasing PDMS content. In a vacuum, as determined from the ESCA data, the relatively non-polar PDMS soft segments preferentially oriented at the surface with increasing PDMS incorporation. Despite the variation in the surface properties, the blood compatibility of these polymers was not significantly affected by the addition of the PDMS-containing polyols.

journal_name

Biomaterials

journal_title

Biomaterials

authors

Okkema AZ,Fabrizius DJ,Grasel TG,Cooper SL,Zdrahala RJ

doi

10.1016/0142-9612(89)90005-7

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

23-32

issue

1

eissn

0142-9612

issn

1878-5905

pii

0142-9612(89)90005-7

journal_volume

10

pub_type

杂志文章

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